Skin science article
Top Stem Cell Serums for Hair Growth Results
Act and Acre, Hairprint, and Vegamour offer stem cell hair growth serums to address thinning hair and hair loss. With its ability to provide deep hydration, stimulate hair growth, and target signs of premature aging follicles, we found that Act and Acre’s seru
Act and Acre, Hairprint, and Vegamour offer stem cell hair growth serums to address thinning hair and hair loss. With its ability to provide deep hydration, stimulate hair growth, and target signs of premature aging follicles, we found that Act and Acre’s serum is the best option overall. Hairprint’s serum is the most affordable option and can improve the scalp microbiome, while Vegamour is ideal for improving hair density and thickness.
Stem cells can regenerate into other cells with specialized functions, making them a valuable tool in tissue regeneration. Stem cell culture preserves stem cells outside of their normal environment and may benefit hair growth by stimulating inactive or damaged hair follicles. Act and Acre, Hairprint, and Vegamour use plant stem cells from apple or curcumin (turmeric). Though plant stem cells are a relatively new ingredient and aren’t yet FDA-approved, they’re unlikely to cause side effects
Read on for our complete review of the best stem cell serums for hair growth, including a detailed overview of each brand. In addition, we spoke with Dr. Jonathan Rick, a board-certified dermatologist, so we could better understand the causes of hair thinning and hair loss.
Act+Acre vs. Hairprint vs. Vegamour | Act+Acre | Hairprint | Vegamour |
|---|---|---|---|
| Price | $86 | $55 | $64 |
| Quantity | 2.2 oz | 1.7 oz | 1 oz |
| Stem cell culture | Swiss Apple Stem Cells (2%) | Apple Fruit Cell Extract | Curcumin Stem Cell Extract |
| Other active ingredients | Bamboo & Pea sprout blend Aloe vera Hyaluronic acid | Radish root culture Coconut milk culture | Red clover Mung bean |
| Blocks DHT? | ❌ | ❌ | ✅ |
| Vegan | ✅ | ✅ | ✅ |
| Hormone free? | ✅ | ✅ | ✅ |
| Clinically tested? | ✅ | ✅ | ✅ |
| Free shipping | 🟡 On orders above $75 | ✅ | 🟡 With subscription |
| Website |
Act and Acre vs. Hairprint
Act and Acre and Hairprint both utilize apple stem cells for hair growth. However, Act and Acre also provides deep scalp hydration and addresses signs of premature aging in hair follicles with bamboo, pea sprout, aloe vera, and hyaluronic acid. Hairprint, on the other hand, encourages a healthy scalp microbiome with radish root and coconut milk culture. Act and Acre is more expensive at $86 for a 2.2-ounce bottle, compared to $55 for a 1.7-ounce bottle of Hairprint’s serum.
Act and Acre vs. Vegamour
Act and Acre’s stem cell serum with Swiss apple stem cell extract supports hair follicle health and hydrates the scalp to promote hair growth. Vegamour, on the other hand, uses curcumin stem cell extract to help naturally block DHT, an androgen that contributes to hair loss. Act and Acre is the more affordable option at $39 per ounce, compared to $64 for a one-ounce bottle of Vegamour.
Hairprint vs. Vegamour
Vegamour’s GRO Hair Serum may help block DHT to prevent hair loss. While Hairprint’s formula with apple fruit cell extract isn’t known to block DHT, it can promote a healthy scalp microbiome with radish root culture and coconut milk culture. Additionally, Hairprint is roughly half the price of Vegamour at $32.35 per ounce (Vegamour costs $64 per ounce).
Act + Acre Stem Cell Serum Review
4.7/5
Rated 4.7 out of 5
- Price/quantity: $86 for 2.2 ounces
- Key ingredients: Swiss apple stem cells (2%), bamboo & pea sprout blend, aloe vera, hyaluronic acid
- Manufacturing method: Cold-processed
- Works best for: Scalp health and premature hair follicle aging
- Begins working in: One month
Act and Acre offers cutting-edge scalp care, addressing concerns like itchiness, oiliness, buildup, and hair thinning. It prioritizes scalp care in hair loss treatments, as a healthy scalp is essential for stronger, thicker, and healthier hair. Additionally, Act and Acre was founded by a board-certified trichologist and offers a two-minute online quiz that will recommend a personalized hair and scalp care system.
Act and Acre Stem Cell Serum Pros & Cons
Pros
- Vegan, plant-based formula that’s free of toxic chemicals
- Promotes scalp health and rejuvenation to support healthy hair growth
- Developed by a trichologist, or a human hair and scalp specialist
Cons
- The 2-ounce bottle may not last for 30 days of use
Does Act and Acre Stem Cell Serum Work?
Act and Acre Stem Cell Serum uses the brand’s H2-Grow Complex™ to address hair loss, hair thinning, and scalp irritation. It includes:
- Swiss Apple Stem Cells (2%) Extract promotes hair follicle health. Apple extract has been found to increase hair length, weight, thickness, and density in animal studies. Further research is required to confirm these results in humans.
- Bamboo and Pea Sprout Blend promotes scalp elasticity and hydration, which may facilitate hair growth. Clinical research has found that topical pea sprout extract improves hair density.
- Aloe Vera soothes the scalp and supports scalp hydration. While the healing benefits of aloe vera are well-documented, there’s no research directly linking it to hair growth.
- Hyaluronic Acid deeply hydrates the scalp, reducing dryness and itchiness.
Act and Acre Reviews
In general, customers love that Act and Acre is a lightweight, fast-absorbing serum that improves scalp health and hair quality. However, some customers didn’t experience a noticeable improvement in hair regrowth after using the serum.
Scalp health☆☆☆☆☆
Gaby“The serum doesn't feel sticky or greasy when applied. It is easily absorbed into the scalp. It hydrates the scalp and helps reduce itchiness.”
Obsessed with this☆☆☆☆☆
Zoe Dawson“I usually don't like to use serums in my hair as it's prone to making it greasy but this one doesn't at all. Have been using it for a month now and loving the results! Will definitely continue to use. Love all their products!!”
Hairprint Stem Cell Regenerator Review
Hairprint Stem Cell Regenerator Review
4.3/5
Rated 4.3 out of 5
- Price: $55 for 1.7 ounces
- Key ingredients: Apple fruit cell extract, radish root culture, coconut milk culture
- Manufacturing method: Unknown
- Works best for: Aging hair follicles, scalp microbiome
- Begins working in: One month
Hairprint offers haircare products with natural ingredients that are safe for all hair types. Along with its gentle washes for gray hair, this brand offers hair regrowth treatments like the Stem Cell Regenerator for the scalp and skin, which features plant-based ingredients. Based out of California, the brand also supports education for girls in developing countries and works to reduce environmental pollutants from hair care products.
Hairprint Stem Cell Serum Pros & Cons
Pros
- More affordable at just over $32 per ounce
- Nourishes the scalp microbiome with probiotic plant cultures
- Promotes cell longevity with plant-based growth and epigenetic factors
Cons
- May also be used on skin, so it may not provide the targeted treatment for hair growth available from other brands
Does Hairprint Stem Cell Serum Work?
Hairprint Stem Cell Serum is formulated to slow hair follicle aging with stem cells from rare alpine apples and encourage a healthy scalp microbiome with plant-based cultures.
- Apple Fruit Cell Culture Extract increased hair length, weight, thickness, and density in animal studies. Further research is required to confirm these results in humans.
- Radish Root Culture (leuconostoc ferment) encourages a healthy scalp microbiome. Additionally, radish root contains significant amounts of sulfur, which promotes keratin production. Keratin is an essential protein for hair growth. Radish root extract has also been found to support hair growth and development in mice, though further research in humans is needed.
- Coconut Milk Culture contains lactobacillus and cocos nucifera ferment to nourish hair and balance the scalp microbiome.
While Hairprint boasts a 4.1-star rating on Amazon, unfortunately, the brand’s stem cell serum doesn’t yet have many other public customer reviews. We’ll update this review as that changes.
Vegamour GRO Hair Serum Review
4.5/5
Rated 5 out of 5
- Price: $64 for one ounce
- Key ingredients: Curcumin stem cell extract, red clover, & mung bean
- Manufacturing method: Unknown
- Works best for: Hair thinning and poor hair density
- Begins working in: 3 months
Vegamour offers 100% vegan and cruelty-free products for hair loss, thinning, and shedding. It uses plant-based, clinically tested ingredients, including curcumin stem cell extract, which naturally blocks DHT. The brand’s holistic approach to hair health is particularly helpful for individuals who want to address the key causes of hair loss without harsh, medicated ingredients.
Vegamour GRO Hair Serum Pros & Cons
Pros
- 100% vegan and cruelty-free, making it a potential good option for many individuals
- Promotes hair density and thickness with natural ingredients
- Naturally blocks DHT with Curcumin Stem Cell Extract
Cons
- Significantly more expensive than other brands
Does Vegamour GRO Hair Serum Work?
Vegamour’s GRO Hair Serum helps thicken, strengthen, and volumize hair with:
- Curcumin Stem Cell Extract is thought to prevent hair loss by acting as a natural DHT inhibitor and supporting IGF-1 and BMP4 production. DHT is a hormone that can shrink hair follicles; IGF-1 is a hormone that promotes hair follicle growth; and BMP4 is a polypeptide that plays an important role in hair regeneration.
- Red Clover may provide natural DHT-inhibiting properties and has been found to boost scalp health in people in the postmenopausal stage of life.
- Mung Bean is rich in copper, a mineral that encourages hair health, and is thought to prevent premature shedding.
Vegamour Reviews
Generally, Vegamour’s customers are satisfied with the serum’s results for hair loss and hair density. Many customers also note that it hydrates and conditions their hair. However, a few customers noted that they had trouble with the bottle dropper design and that the product is expensive.
So far so good!☆☆☆☆☆
Mickey“I am suffering from thinning hair in the front, I believe due to age...60+.....heard good reviews...wanted to give this a try...I have been using it for 3 weeks now and do see less hair loss as well as the serum does help give the appearance of MORE body, almost like a mousse. It is a tad bit oily, but again..acts like a conditioning hair product. Using a full dropper a day, I have only used half the bottle, so it is cost effective and I will continue to use it. Hope to see some more emprovement by the 2nd or 3rd month.”
It works, but you must use it daily and consistently. Not an overnight fix.☆☆☆☆☆
“I have been using this for 6 months now and it continues to work. I'm also using the shampoo and conditioner. The first 4 months I used it twice a day (morning and evening). Once I had a good amount of regrowth, I started using it once a day, and I haven't noticed any loss so far. I will continue to use it once a day for maintenance and we'll see how it goes. My only criticism is the dropper bottle design. It is impossible to fill the dropper adequately and can be difficult to portion out how much product one should use. A redesign would be useful.”
What Are The Side Effects Of Stem Cell Serums?
Stem cell therapy derived from animal or human sources can lead to side effects including infection and unwanted immune response. Topical plant stem cell serums pose a far lower risk of side effects, as they’re derived from natural sources. However, scalp irritation and changes in hair texture are possible.
Before trying a stem cell serum, it’s best to speak with your healthcare provider to ensure it is safe for you to do so. In some cases, there may be an underlying cause that will need to be addressed.
A Word From Our Expert
— Dr. Jonathan Rick
There are many types of hair loss, many of which require evaluation by an experienced physician to adequately diagnose. However, androgenic alopecia is very common and treatable. This type of hair loss is caused by the interaction of hormones on hair receptors. Some people have hair that is very sensitive to hormones and notice more hair loss than others their age.”
When to Seek Emergency Medical Care
Seek emergency medical care while using stem cell serums if you experience symptoms of a severe allergic reaction, including:
- Skin rash, hives, or severe itching
- Swelling of the lips, throat, or tongue
- Shortness of breath
- Difficulty breathing
- Dizziness
- Fainting
The Verdict: Which Is the Best Stem Cell Hair Serum?
Act and Acre, Hairprint, and Vegamour all offer hair serums with plant stem cells to promote hair growth.
Act and Acre is the best overall.
Act and Acre is our pick for the best overall, as it uses a trichologist-formulated blend of plant-based ingredients, including Swiss apple stem cell extract, to promote scalp health, provide deep hydration, and target signs of prematurely aging hair follicles. The cold-processed formula starts working within just one month.
Hairprint is the most affordable.
Hairprint is the most affordable formula at $55 for 1.7 ounces. The formula contains apple fruit cell extract to promote cell longevity, as well as probiotic plant cultures to nourish the scalp microbiome. However, it may be used on skin and therefore doesn’t offer as many targeted active ingredients for hair growth as other formulas.
Vegamour works best for boosting hair density.
Vegamour is the best option for hair density and thinning. It’s the only formula that can naturally block DHT with curcumin stem cell extract. However, it’s significantly more expensive than Act and Acre and Hairprint at $64 for one ounce.
Frequently Asked Questions (FAQs)
Methodology
To compile this list, we looked at hair growth stem cell serums that have a minimum rating of 4 stars. Only serums that offer science-backed ingredients and proven results were considered. We then narrowed the list down to a few stem cell serums and poured through customer reviews and validated their claims with relevant and up-to-date research to complete our evaluation. We preferred serums with research-backed ingredients, expert credentials, and good customer service. In the end, we selected Act and Acre as the best overall because of its broad range of benefits for hair loss and thinning.
| Review Process | Key Metrics | Weighting |
|---|---|---|
| Purchase online | - ease to complete intake form - affordability - upfront commitment or subscription required? - money back guarantee or refund policy? | 1 |
| Shipping + unboxing | - shipping cost - time from order to treatment delivery - sustainable packaging | 1 |
| Testing + journal for 1-3 months | - ease of use - transition into habitual use - taste / smell / feel / pain | 1.5 |
| Results after 3 months of use | - efficacy / results - ease of forming a health habit - requires additional purchae? - responsive customer support - willingness to recommend to a friend | 1.5 |
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