Tosowoong Copper Peptide 12 Cream Versus Theramid Copper Peptide

Tosowoong Copper Peptide 12 Cream Versus Theramid Copper Peptide

This anti-aging moisturizer is formulated around Collagen Water and Niacinamide to soften the look of wrinkles.

This anti-aging serum is formulated around Copper Tripeptide-1 and Bifida Ferment Lysate to soften the look of wrinkles and strengthen the skin barrier.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Collagen Water

Butylene Glycol

Glycerin

Ethylhexyl Palmitate

Isopropyl Palmitate

Niacinamide

1,2-Hexanediol

Caprylic/Capric Triglyceride

Cetearyl Alcohol

Vinyldimethicone

Polyglyceryl-2 Stearate

Hydroxyacetophenone

Glyceryl Stearate

Stearyl Alcohol

Ammonium Acryloyldimethyltaurate/Vp Copolymer

Arginine

Carbomer

Castor Oil/Ipdi Copolymer

Copper Tripeptide-1

Panthenol

Sodium Hyaluronate

Allantoin

Adenosine

Disodium EDTA

Gellan Gum

Agar

Alcohol

Tris(Tetramethylhydroxypiperidinol)Citrate

Melia Azadirachta Leaf Extract

Melia Azadirachta Flower Extract

Coccinia Indica Fruit Extract

Xanthan Gum

Solanum Melongena Fruit Extract

Eclipta Prostrata Extract

Ocimum Sanctum Leaf Extract

Simmondsia Chinensis Seed Oil

Corallina Officinalis Extract

Curcuma Longa Root Extract

Ethylhexylglycerin

Lecithin

Polysorbate 20

Moringa Oleifera Seed Oil

Atelocollagen

Desamido Collagen

Hydrolyzed Collagen

Dimethylsilanol Hyaluronate

Hydrolyzed Hyaluronic Acid

Hydrolyzed Sodium Hyaluronate

Soluble Collagen

Hyaluronic Acid

Potassium Hyaluronate

Sodium Hyaluronate Crosspolymer

Collagen

Collagen Amino Acids

Sodium Hyaluronate Dimethylsilanol

Sodium Acetylated Hyaluronate

Sodium Ascorbyl Phosphate

Procollagen

Tripeptide-1

Tripeptide-29

Hexapeptide-12

Nicotinoyl Tripeptide-35

Palmitoyl Tripeptide-1

Acetyl Hexapeptide-8

Hexapeptide-9

Nonapeptide-7

Palmitoyl Pentapeptide-4

Palmitoyl Tetrapeptide-7

Palmitoyl Tripeptide-29

Water, Collagen Water, Butylene Glycol, Glycerin, Ethylhexyl Palmitate, Isopropyl Palmitate, Niacinamide, 1,2-Hexanediol, Caprylic/Capric Triglyceride, Cetearyl Alcohol, Vinyldimethicone, Polyglyceryl-2 Stearate, Hydroxyacetophenone, Glyceryl Stearate, Stearyl Alcohol, Ammonium Acryloyldimethyltaurate/Vp Copolymer, Arginine, Carbomer, Castor Oil/Ipdi Copolymer, Copper Tripeptide-1, Panthenol, Sodium Hyaluronate, Allantoin, Adenosine, Disodium EDTA, Gellan Gum, Agar, Alcohol, Tris(Tetramethylhydroxypiperidinol)Citrate, Melia Azadirachta Leaf Extract, Melia Azadirachta Flower Extract, Coccinia Indica Fruit Extract, Xanthan Gum, Solanum Melongena Fruit Extract, Eclipta Prostrata Extract, Ocimum Sanctum Leaf Extract, Simmondsia Chinensis Seed Oil, Corallina Officinalis Extract, Curcuma Longa Root Extract, Ethylhexylglycerin, Lecithin, Polysorbate 20, Moringa Oleifera Seed Oil, Atelocollagen, Desamido Collagen, Hydrolyzed Collagen, Dimethylsilanol Hyaluronate, Hydrolyzed Hyaluronic Acid, Hydrolyzed Sodium Hyaluronate, Soluble Collagen, Hyaluronic Acid, Potassium Hyaluronate, Sodium Hyaluronate Crosspolymer, Collagen, Collagen Amino Acids, Sodium Hyaluronate Dimethylsilanol, Sodium Acetylated Hyaluronate, Sodium Ascorbyl Phosphate, Procollagen, Tripeptide-1, Tripeptide-29, Hexapeptide-12, Nicotinoyl Tripeptide-35, Palmitoyl Tripeptide-1, Acetyl Hexapeptide-8, Hexapeptide-9, Nonapeptide-7, Palmitoyl Pentapeptide-4, Palmitoyl Tetrapeptide-7, Palmitoyl Tripeptide-29

Propanediol

Dimethicone

Hydrogenated Ethylhexyl Olivate

Betaine

Isododecane

PEG-10 Dimethicone

Bifida Ferment Lysate

PEG/PPG-18/18 Dimethicone

Magnesium Sulfate

Hydrogenated Castor Oil/Sebacic Acid Copolymer

Acetyl Hexapeptide-1

Acetyl Tetrapeptide-2

Trifluoroacetyl Tripeptide-2

Sh-Oligopeptide-1

Sh-Oligopeptide-2

Sh-Polypeptide-1

Sh-Polypeptide-9

Sh-Polypeptide-11

Bacillus/Folic Acid Ferment Filtrate Extract

Acetyl Glutamine

Disteardimonium Hectorite

Hydrogenated Olive Oil Unsaponifiables

Propylene Carbonate

Caprylyl Glycol

Dextran

Tocopherol

Acetic Acid

Lactic Acid

Sodium Benzoate

Phenoxyethanol

Water, Propanediol, Dimethicone, Hydrogenated Ethylhexyl Olivate, Betaine, Isododecane, PEG-10 Dimethicone, Copper Tripeptide-1, Bifida Ferment Lysate, Glycerin, PEG/PPG-18/18 Dimethicone, Magnesium Sulfate, Hydrogenated Castor Oil/Sebacic Acid Copolymer, Sodium Hyaluronate, Acetyl Hexapeptide-1, Acetyl Tetrapeptide-2, Trifluoroacetyl Tripeptide-2, Sh-Oligopeptide-1, Sh-Oligopeptide-2, Sh-Polypeptide-1, Sh-Polypeptide-9, Sh-Polypeptide-11, Bacillus/Folic Acid Ferment Filtrate Extract, Acetyl Glutamine, Disteardimonium Hectorite, Hydrogenated Olive Oil Unsaponifiables, Propylene Carbonate, Lecithin, Caprylyl Glycol, Butylene Glycol, Dextran, Tocopherol, Acetic Acid, Lactic Acid, Disodium EDTA, Sodium Benzoate, 1,2-Hexanediol, Ethylhexylglycerin, Phenoxyethanol

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Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse.

It is a:

Humectant, drawing moisture into the skin

Emollient, helping to soften skin

Solvent, dispersing and stabilizing formulas

Preservative booster, enhancing the antimicrobial activity of other preservatives

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.

Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.

Copper Tripeptide-1 (GHK-Cu) is a skin repairing ingredient known for its ability to boost collagen, improve firmness, and support skin regeneration.

It is a complex made up of a naturally occurring peptide (glycine-histidine-lysine) and copper, an essential trace element.

While studying wound healing, researchers noticed GHK-Cu stimulated hair follicle enlargement and growth by keeping hair in its active growth phase longer. This has made it a promising ingredient for hair regrowth treatments.

Some people have reported increased facial hair. While GHK-Cu can make your hair follicles bigger, it usually doesn’t turn soft, barely-visible facial hairs into thick, dark ones.

Anecdotal reports suggest that overusing copper peptides might lead to premature aging due to excess free copper or enzyme imbalances. This claim isn’t backed by large-scale studies.

Unfortunately, there are limited human studies for this ingredient. While early results are promising, many studies are either small, in-vitro, or not rigorously controlled.

For example, there is a 1998 study that explored the effects of copper tripeptide, vitamin C, tretinoin, and melatonin on skin repair and collagen synthesis.

After one month, increased procollagen production was seen in 7 out of 10 participants using copper tripeptide (more than those using vitamin C, melatonin, or tretinoin.

While the study was exploratory, it offers early evidence that copper tripeptide may support collagen production. Larger, well-designed trials are still needed to confirm its potential and understand individual responses.

Read more about other common types of peptides here:

Disodium EDTA is a chelating agent. It grabs onto and deactivates metal ions that sneak into your products from water, packaging, or air.

This ingredient mainly works behind the scenes and helps with:

On top of that, this ingredient can counteract the effects of hard water by binding to the minerals in it.

One thing worth knowing is that Disodium EDTA has been shown to be a mild penetration enhancer. It can help other ingredients absorb into skin more effectively which can be a double-edged sword (great for actives, but can also make the active too strong if you have sensitive skin).

Clinical patch testing showed no significant skin irritation at typical use concentrations and minimal dermal absorption.

You'll most likely see this ingredient near the end of an ingredient list. It's typically found in concentrations less than 1%.

Ethylhexylglycerin is created from glycerin. It is a multitasker ingredient that:

The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.

Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Lecithin is a term for a group of substances found in the cell membranes of plants, animals, and humans. They are made up of phospholipids.

Thanks to its amphiphilic structure (water-loving head and oil-loving tail), it is a true multitasker:

It plays well with most ingredients and is typically used at 0.1-1%. However, concentrations up to 50% have been reported in moisturizers.

Sodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity.

In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface.

Interestingly, the size of the molecule affects its behavior:

Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.

Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.

You'll typically see concentrations between 0.1-2% for this ingredient.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

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