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Skin science article

Transparent Lab Bakuchiol Firming Cream Versus The INKEY List Bakuchiol Moisturizer

Transparent Lab Bakuchiol Firming Cream Versus The INKEY List Bakuchiol Moisturizer This anti-aging treatment is formulated around Bakuchiol and Palmitoyl Tripeptide-1 to soften the look of wrinkles and refine skin texture. This anti-aging moisturizer is formu

Transparent Lab Bakuchiol Firming Cream Versus The INKEY List Bakuchiol Moisturizer

This anti-aging treatment is formulated around Bakuchiol and Palmitoyl Tripeptide-1 to soften the look of wrinkles and refine skin texture.

This anti-aging moisturizer is formulated around Bakuchiol and Squalane to soften the look of wrinkles and refine skin texture.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Glycerin

Caprylic/Capric Triglyceride

Tribehenin PEG-20 Esters

Dimethicone

Squalane

Propanediol

Coco-Caprylate

C10-18 Triglycerides

Tricaprylin

Bakuchiol

Cetearyl Alcohol

Ceramide Ng

Hydrolyzed Hyaluronic Acid

Palmitoyl Tripeptide-1

Palmitoyl Tetrapeptide-7

Centella Asiatica Callus Conditioned Media

Lactococcus Ferment Lysate

Dimethicone/Vinyl Dimethicone Crosspolymer

Xanthan Gum

Acrylates/C10-30 Alkyl Acrylate Crosspolymer

Butylene Glycol

Carbomer

Sodium Lactate

Lactic Acid

Polysorbate 20

Tocopherol

Caprylyl Glycol

Citric Acid

Sodium Chloride

Sodium Benzoate

Tocopheryl Acetate

Ethylhexylglycerin

Phenoxyethanol

Water, Glycerin, Caprylic/Capric Triglyceride, Tribehenin PEG-20 Esters, Dimethicone, Squalane, Propanediol, Coco-Caprylate, C10-18 Triglycerides, Tricaprylin, Bakuchiol, Cetearyl Alcohol, Ceramide Ng, Hydrolyzed Hyaluronic Acid, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Centella Asiatica Callus Conditioned Media, Lactococcus Ferment Lysate, Dimethicone/Vinyl Dimethicone Crosspolymer, Xanthan Gum, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Butylene Glycol, Carbomer, Sodium Lactate, Lactic Acid, Polysorbate 20, Tocopherol, Caprylyl Glycol, Citric Acid, Sodium Chloride, Sodium Benzoate, Tocopheryl Acetate, Ethylhexylglycerin, Phenoxyethanol

Plukenetia Volubilis Seed Oil

Dicaprylyl Carbonate

Sodium Caproyl Prolinate

Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer

Sodium Hydroxide

Sodium Stearoyl Glutamate

Polysorbate 60

Phytic Acid

Glyceryl Polyacrylate

Sorbitan Isostearate

Water, Squalane, Glycerin, Propanediol, Plukenetia Volubilis Seed Oil, Dicaprylyl Carbonate, Bakuchiol, Phenoxyethanol, Sodium Caproyl Prolinate, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Carbomer, Sodium Hydroxide, Ethylhexylglycerin, Sodium Stearoyl Glutamate, Polysorbate 60, Phytic Acid, Glyceryl Polyacrylate, Sorbitan Isostearate, Tocopherol

Reviews

Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Bakuchiol is a plant-derived antioxidant from the seeds of the Psoralea corylifolia plant. It has antimicrobial, emollient, skin conditioning, and antioxidant properties.

You'll likely see it called a "retinol replacement" but the two are technically not related. This is because bakuchiol is able to flip many of the same switches in your skin cells to tell them to:

1) produce more collagen (type I, III, and IV) 2) activate the same genes retinoids do

Unlike retinoids, this ingredient will not increase photosensitivity and is safe to use during pregnancy (but please still check in with your doctor!).

The flagship clinical trial from Dhaliwal et al. 2019 found 0.5% bakuchiol (twice daily) and 0.5% retinol (once daily) reduced wrinkles and hyperpigmentation equally, but bakuchiol had significantly less irritation.

Systematic reviews also back this up:

Bakuchiol is comparable to retinol for photoaging but with better tolerability. It also has mild antibacterial properties against Cutibacterium acnes and antifungal activity in vitro against Candida and dermatophytes.

The reason bakuchiol works well is due to its structure; it is a meroterpene phenol, or a hybrid molecule. The phenol half acts as an antioxidant while the terpene half is fat-loving. This helps the molecule slip through the skin barrier.

This ingredient is usually used between 0.5-2%. Only one case of contact dermatitis has ever been reported for this ingredient.

Carbomer is a synthetic thickening and gelling agent. It's basically the ingredient that gives a lot of serums, gels, creams, and sunscreens their smooth, non-sticky texture.

Although legally permitted at very high levels, carbomers are normally used at concentrations below 1%.

It also needs to be neutralized to actually thicken, and because it is a large molecule, it doesn't really penetrate the skin barrier.

Allergy-wise, the risk is very low. Clinical studies show carbomers have low potential for skin irritation/sensitization even at concentrations up to 100%.

A 2024 UK study patch-tested 1,302 patients and found true allergy to the parent group of carbomer to be rare with no confirmed relevant reactions.

Ethylhexylglycerin is created from glycerin. It is a multitasker ingredient that:

The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.

Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).

It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.

On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.

Another perk of this ingredient is that it stays functional across a wide pH range (3-10).

You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.

Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.

Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.

Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.

Propanediol is an all-star ingredient. It softens, hydrates, and smooths the skin.

It’s often used to:

Propanediol is not likely to cause sensitivity and considered safe to use. It is derived from corn or petroleum with a clear color and no scent.

Squalane is the hydrogenated and shelf-stable form of squalene (a lipid that naturally occurs in human sebum).

It is an emollient and skin conditioning agent that is able to integrate seamlessly into the skin's lipid barrier without clogging pores.

This is due to how structurally similar it is to what your skin already produces.

Though it is mostly an emollient that helps soften and hydrate skin, it also has some humectant and occlusive action. Humectants help the skin retain moisture while occlusives seal it in, making squalane a triple-threat moisturizer.

Research shows it has antioxidant capabilities that help protect against stressors like UV exposure, specifically UVA induced oxidative stress. This study also found that it supports collagen biosynthesis in human dermal fibroblasts.

No clinical study has reported significant adverse effects and irritation reactions are very rare from this ingredient (even at 100% concentration).

Overall, it's a fantastic ingredient for hydration and is suitable for all skin types.

This depends on the source. Squalane can be derived from both plants and animals. Most squalane used in skincare comes from plants.

Please note: the source of squalane is only known if disclosed by the brand. We recommend reaching out to the brand if you have any questions about their squalane.

Read more about squalene with an "e".

Though squalane is often called an oil, it’s technically not one. It is a hydrocarbon, meaning it is only made of carbon and hydrogen. True oils are triglycerides and made of fatty acids and glycerol.

The term “oil-free” isn’t regulated so companies can define it however they want. Some exclude all oils, while others just avoid mineral oil or comedogenic oils.

Squalane has a comedogenic rating of 1 from the original 1972 study that tested raw ingredients under occlusion on rabbit ears. This system is not standardized or peer-reviewed, and using the raw ingredients is very different from how diluted cosmetic formulations are used on human skin.

A comedogenic rating of 1 means it is "unlikely to clog pores" according to the original rating system.

The overall formula of a product matters more than the individual ingredients on whether or not it will cause clogged pores.

Tocopherol is a fat-soluble antioxidant known as Vitamin E.

You'll find this ingredient in the vast majority of skincare (for good reason). It works to neutralize free radicals, or unstable molecules generated by UV exposure, pollution, and other environmental stressors, before they can cause oxidative damage to your skin cells.

Topically applied tocopherol has been shown to protect against UV damage by ramping up the skin's own natural defense enzymes.

It also acts as a skin conditioning agent; some studies show that regular topical use can improve the skin's water-binding capacity over 2-4 weeks.

This ingredient is especially loved for being a team player. When combined with Vitamin C, the photoprotective effect of both ingredients roughly doubles and the combo also helps reduce UV-induced DNA damage.

This ingredient has some brightening potential but it's more of a prevention ingredient than spot-fader. Cell studies show it can slow down melanin production but it's worth noting that it's not the most powerful brightener out there.

In formulations, it also serves as a stabilizer that helps protect other oxidation-prone ingredients from degrading.

Concentrations usually range from 0.1-1% in most leave-on products.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

Similar Comparisons

The reference edit

Ingredients, questions
& further reading.

Connected source records selected through this article’s public topic index.

01

Formula cabinet

Ingredients & structured notes

Ingredient index

Ingredients Side-by-side

  1. 01Water
  2. 02Propanediol
  3. 03Sodium Hyaluronate
  4. 04Glycerin
  5. 05Butylene Glycol
  6. 06Phenoxyethanol
  7. 07Ammonium Acryloyldimethyltaurate/Vp Copolymer
  8. 08Leuconostoc/Radish Root Ferment Filtrate
  9. 09Hyaluronic Acid
  10. 10Carbomer
  11. 11Sodium Lactate
  12. 12Polysorbate 20
  13. 13Palmitoyl Tetrapeptide-7
  14. 14Palmitoyl Tripeptide-1
  15. 15Water, Propanediol, Sodium Hyaluronate, Glycerin, Butylene Glycol, Phenoxyethanol, Ammonium Acryloyldimethyltaurate/Vp Copolymer, Leuconostoc/Radish Root Ferment Filtrate, Hyaluronic Acid, Carbomer, Sodium Lactate, Polysorbate 20, Palmitoyl Tetrapep…
  16. 16Pentylene Glycol
  17. 17Dipropylene Glycol
  18. 18Hydrolyzed Hyaluronic Acid
  19. 19Sodium Acetylated Hyaluronate
  20. 20Diglycerin
Source · skinsort.com
02

Product index

Related product references

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03

Comparison edit

Read side by side