Skin science article
Tula Skincare A+ Renewal Advanced Retinal & Peptides Serum Versus Rodan + Fields Redefine Intensive Renewing Serum
Tula Skincare A+ Renewal Advanced Retinal & Peptides Serum Versus Rodan + Fields Redefine Intensive Renewing Serum This anti-aging serum is formulated around Retinal and Lactococcus Ferment Lysate to soften the look of wrinkles and refine skin texture. This an
Tula Skincare A+ Renewal Advanced Retinal & Peptides Serum Versus Rodan + Fields Redefine Intensive Renewing Serum
This anti-aging serum is formulated around Retinal and Lactococcus Ferment Lysate to soften the look of wrinkles and refine skin texture.
This anti-aging serum is formulated around Retinal to soften the look of wrinkles and refine skin texture.
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Propanediol
C15-19 Alkane
Glycerin
1,2-Hexanediol
Lactococcus Ferment Lysate
Pentylene Glycol
Cetyl Alcohol
Chlorella Vulgaris Extract
Vaccinium Macrocarpon Fruit Extract
Tridecapeptide-1
Ceramide AP
Ceramide As
Ceramide Ns
Ceramide EOP
Ceramide NP
Sodium Hyaluronate
Hydrolyzed Sodium Hyaluronate
Sodium Acetylated Hyaluronate
Sodium Hyaluronate Crosspolymer
Aloe Barbadensis Leaf Juice
Lactobacillus
Curcuma Longa Root Extract
Lactobacillus Ferment
Beta Vulgaris Root Extract
Retinal
Arginine
Diisostearyl Malate
Alpha-Glucan Oligosaccharide
Bisabolol
Inulin
Arachidyl Alcohol
Lactic Acid
Sclerotium Gum
Citric Acid
Behenyl Alcohol
Malic Acid
Polymnia Sonchifolia Root Juice
Arachidyl Glucoside
Hydrogenated Lecithin
Polyacrylate Crosspolymer-6
Cellulose Gum
Glucose
Calcium Chloride
Fructose
Cholesterol
Sodium Phytate
2,3-Butanediol
Calcium Alginate
Glyceryl Stearate
Lecithin
Cellulose
Sodium Hydroxide
Ethylhexylglycerin
Caprylyl Glycol
Maltodextrin
Xanthan Gum
Sodium Benzoate
Butylene Glycol
Sodium Chloride
Potassium Sorbate
Water, Propanediol, C15-19 Alkane, Glycerin, 1,2-Hexanediol, Lactococcus Ferment Lysate, Pentylene Glycol, Cetyl Alcohol, Chlorella Vulgaris Extract, Vaccinium Macrocarpon Fruit Extract, Tridecapeptide-1, Ceramide AP, Ceramide As, Ceramide Ns, Ceramide EOP, Ceramide NP, Sodium Hyaluronate, Hydrolyzed Sodium Hyaluronate, Sodium Acetylated Hyaluronate, Sodium Hyaluronate Crosspolymer, Aloe Barbadensis Leaf Juice, Lactobacillus, Curcuma Longa Root Extract, Lactobacillus Ferment, Beta Vulgaris Root Extract, Retinal, Arginine, Diisostearyl Malate, Alpha-Glucan Oligosaccharide, Bisabolol, Inulin, Arachidyl Alcohol, Lactic Acid, Sclerotium Gum, Citric Acid, Behenyl Alcohol, Malic Acid, Polymnia Sonchifolia Root Juice, Arachidyl Glucoside, Hydrogenated Lecithin, Polyacrylate Crosspolymer-6, Cellulose Gum, Glucose, Calcium Chloride, Fructose, Cholesterol, Sodium Phytate, 2,3-Butanediol, Calcium Alginate, Glyceryl Stearate, Lecithin, Cellulose, Sodium Hydroxide, Ethylhexylglycerin, Caprylyl Glycol, Maltodextrin, Xanthan Gum, Sodium Benzoate, Butylene Glycol, Sodium Chloride, Potassium Sorbate
Cyclopentasiloxane
Dimethicone
Polysilicone-11
Ethylhexyl Hydroxystearate
C12-15 Alkyl Benzoate
Palmitoyl Hexapeptide-14
Retinyl Palmitate
Hydroxyapatite
Bis-Ethylhexyl Hydroxydimethoxy Benzylmalonate
Ethoxydiglycol
Cyclopentasiloxane, Dimethicone, Polysilicone-11, Ethylhexyl Hydroxystearate, C12-15 Alkyl Benzoate, Retinal, Palmitoyl Hexapeptide-14, Retinyl Palmitate, Hydroxyapatite, Bis-Ethylhexyl Hydroxydimethoxy Benzylmalonate, Ethoxydiglycol
Alternatives
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Retinal (aka retinaldehyde) is a form of retinoid that formulators use mainly as an antiaging and skin-renewing active.
What makes it special is its position in the retinoid family; skin converts it to retinoic acid (the prescription gold standard) in just one step.
Because retinal only requires 1 conversion step to become retinoic acid, it's the strongest over-the-counter retinoid. It also works at lower concentrations than retinol, since retinal is about 10x more bioavailable.
Studies back up its efficacy in skin:
A foundational trial showed that applying 0.05-0.5% retinal for 1-3 months produced a dose-dependent and significant increase in epidermal thickness + cell turnover markers.
And a head-to-head comparison of 0.05% retinal against a 0.05% retinoid acid found both formulations were effective for the basis of wrinkle/skin roughness features, but retinoic acid caused more local irritation.
More recent controlled trials confirm it improves wrinkles, dermal density, and firmness over 12-24 weeks, with significant improvements in skin texture and firmness (particularly with the higher 0.1% concentration).
Retinal also has one trick the other retinoids do not: it directly fights against acne bacteria since a clinical study showed retinaldehyde-treated areas displayed a significant decrease in counts of viable P. acnes.
This makes it a great pick for people who want to treat aging and breakouts.
Typical cosmetic use sits in the 0.05-0.1% range with 0.05% being the gentle starting point and 0.1% giving stronger results.
Like all retinoids, retinal works best with nightly use, a good moisturizer, and daytime sunscreen. It can cause some irritation so ease into it slowly rather than going all in.
The "ramp up" method works well: start with Retinal once a week to give your skin time to adjust, which keeps irritation low.
Slowly add more nights until you reach your goal frequency once your skin feels comfortable.
Retinoids also make your skin more sensitive to the sun in the first few weeks, so wear sunscreen every morning and protect your skin from direct sun while you build up tolerance.