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ZAPZYT Acne Treatment Gel Versus Paula's Choice Regular Strength Daily Skin Clearing Treatment with 2.5% Benzoyl Peroxide

ZAPZYT Acne Treatment Gel Versus Paula's Choice Regular Strength Daily Skin Clearing Treatment with 2.5% Benzoyl Peroxide This acne treatment is formulated around Benzoyl Peroxide to clear breakouts. This acne treatment is formulated around Benzoyl Peroxide an

ZAPZYT Acne Treatment Gel Versus Paula's Choice Regular Strength Daily Skin Clearing Treatment with 2.5% Benzoyl Peroxide

This acne treatment is formulated around Benzoyl Peroxide to clear breakouts.

This acne treatment is formulated around Benzoyl Peroxide and Bisabolol to clear breakouts and calm redness.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Benzoyl Peroxide 10%

Laureth-4

Carbomer

EDTA

Dimethyl Isopropanolamine

Water

Benzoyl Peroxide 10%, Laureth-4, Carbomer, EDTA, Dimethyl Isopropanolamine, Water

Propylene Glycol

Benzoyl Peroxide

Bisabolol

Allantoin

Acrylates/C10-30 Alkyl Acrylate Crosspolymer

Hydroxyethylcellulose

Sodium Citrate

Caprylyl Glycol

Sodium Hydroxide

Disodium EDTA

Hexylene Glycol

Phenoxyethanol

Water, Propylene Glycol, Benzoyl Peroxide, Bisabolol, Allantoin, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Hydroxyethylcellulose, Sodium Citrate, Laureth-4, Caprylyl Glycol, Sodium Hydroxide, Disodium EDTA, Hexylene Glycol, Phenoxyethanol

Reviews

Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Benzoyl Peroxide (BPO) is one of the most studied and widely used acne-fighting ingredients on the market for over five decades.

It works by releasing oxygen into your pores to kill Cutibacterium acne, or the bacteria closely linked to acne breakouts. This bacteria has a hard time surviving in an oxygen-rich environment.

On top of that, BPO has keratolytic properties to help shed dead skin cells and keep pores from getting clogged.

One of the coolest things about BPO is that bacteria do not develop resistance to it the way they can with antibiotics. That's why dermatologists recommend pairing it with topical antibiotics to keep resistance at bay.

BPO is usually available in 2.5%, 5%, and 10% concentrations. Research has shown that 2.5% tends to be just as effective as the higher strengths while being more gentle on the skin.

The FDA has classified BPO as a safe and effective acne treatment. You'll be able to find this ingredient in over-the-counter products in many countries.

Just so you know, BPO is a known mild irritant. It's common to see dryness, peeling, and some redness when you first start using it. This usually goes away as your skin adjusts.

A very small number of people might develop allergic contact dermatitis from it as patch test studies show positive reactions in about 1-5% of patients.

Once BPO is absorbed into the skin, our bodies turn it into benzoic acid and quickly exits in urine. It's also worth noting that BPO will bleach fabrics and hair, so watch your towels and pillowcases!

Laureth-4 is created by reacting ethylene oxide with Lauryl Alcohol. It is a surfactant and emulsifier.

Surfactants reduce the surface tension of ingredients so they can mix better. Emulsifiers prevent ingredients such as oil and water from separating.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

Similar Comparisons

The reference edit

Ingredients, questions
& further reading.

Connected source records selected through this article’s public topic index.

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Formula cabinet

Ingredients & structured notes

Ingredient index

Ingredients Explained

  1. 01These ingredients are found in both products.
  2. 02Ingredients higher up in an ingredient list are typically present in a larger amount.
  3. 03Adenosine is a purine nucleoside that your body already makes in every cell. In skincare, it acts mainly as a skin conditioning and anti-aging agent.
  4. 04The way it works is fairly well mapped out:
  5. 05Your skin has cells called fibroblasts that build collagen (the stuff that keeps skin firm and smooth). Adenosine basically flips a switch on these cells that tells them to get to work making more collagen and other proteins. These cells slow down o…
  6. 06The clinical backing is pretty solid too.
  7. 07A blind, randomized, placebo-controlled trial of 126 women aged 45-65 tested a 0.1% cream twice daily and found real improvements in crow's feet and frown lines using a precise 3D skin-mapping technique; these changes showed up by week 3 and held at…
  8. 08A later study using Adenosine-loaded dissolving microneedle patches reported gains in wrinkle depth, dermal density, elasticity, and hydration.
  9. 09On concentrations, South Korea's Ministry of Food and Drug Safety has set 0.04% as the approved functional anti-wrinkle level. You'll typically see this ingredient used somewhere in the 0.04-0.1% range since it works at low doses.
  10. 10This ingredient has been found safe for cosmetics with the data showing no irritation or sensitization.
  11. 11Overall, this is a great ingredient for any anti-aging routine and has no photosensitizing effect, so it suits both AM and PM use.
  12. 12Allantoin is a soothing ingredient known for its protective and moisturizing properties; it's basically a quiet workhorse ingredient you can find in a huge range of cosmetics.
  13. 13Though it can be derived from the comfrey plant, allantoin is produced synthetically for cosmetic products to ensure purity.
  14. 14Research shows it can encourage your skin cells to turn over and renew by stimulating keratinocyte and fibroblast proliferation.
  15. 15It also has mild keratolytic properties to help loosen and shed dead skin cells without being harsh.
  16. 16Studies also suggest allantoin can help calm inflammation by dialing down some of the chemical signals your skin sends out when it is irritated.
  17. 17This ingredient is typically used in the 0.1-0.5% range, and the FDA recognizes it as a skin protectant in OTC products up to 2%.
  18. 18Overall, allantoin is a wonderful addition to most routines; it is stable across a wide pH range (~4-8), works well with other ingredients, and is considered non-sensitizing/non-irritating.
  19. 19Fun fact: Allantoin is naturally occurring in comfrey root, beets, chamomile, and wheat sprouts. Our bodies even produce it as a byproduct of uric acid metabolism.
  20. 20Aminomethyl Propanol is used to adjust the pH of products. It is also used as a base to create other organic compounds. Having a balanced pH is important for protecting your skin.
Source · skinsort.com
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Product index

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Comparison edit

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