ZO Skin Health Brightalive® Versus Paula's Choice Discoloration Repair Serum

ZO Skin Health Brightalive® Versus Paula's Choice Discoloration Repair Serum

This brightening serum is formulated around Niacinamide and Aminopropyl Ascorbyl Phosphate to brighten dull-looking skin and fade the look of dark spots.

This brightening serum is formulated around Niacinamide and Tranexamic Acid to fade the look of dark spots and brighten dull-looking skin.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Glycerin

Dimethicone

Niacinamide

Caprylyl Methicone

C12-15 Alkyl Benzoate

Glyceryl Stearate

PEG-100 Stearate

Acrylamide/Ammonium Acrylate Copolymer

Aminopropyl Ascorbyl Phosphate

Cetyl Alcohol

PEG-12 Dimethicone/PPG-20 Crosspolymer

Tranexamic Acid

Acetyl Glucosamine

Dipotassium Glycyrrhizate

Diglucosyl Gallic Acid

Beta-Glucan

Papain

Lactic Acid/Glycolic Acid Copolymer

Palmitoyl Sh-Octapeptide-24 Amide

Palmitoyl Sh-Tripeptide-5 Norisoleucyl Sh-Nonapeptide-1

Elaeis Guineensis Oil

Gossypium Herbaceum Seed Oil

Linum Usitatissimum Seed Oil

Bidens Pilosa Extract

Tocopherol

Sodium Bisulfite

Tocopheryl Acetate

Ascorbic Acid

Retinyl Palmitate

Xanthan Gum

Polyisobutene

Polymethyl Methacrylate

Polyvinyl Alcohol

Polysorbate 20

Disodium EDTA

1,2-Hexanediol

Carbomer

Algin

Sodium Hydroxide

Parfum

Phenoxyethanol

Caprylyl Glycol

Chlorphenesin

Pentylene Glycol

Water, Glycerin, Dimethicone, Niacinamide, Caprylyl Methicone, C12-15 Alkyl Benzoate, Glyceryl Stearate, PEG-100 Stearate, Acrylamide/Ammonium Acrylate Copolymer, Aminopropyl Ascorbyl Phosphate, Cetyl Alcohol, PEG-12 Dimethicone/PPG-20 Crosspolymer, Tranexamic Acid, Acetyl Glucosamine, Dipotassium Glycyrrhizate, Diglucosyl Gallic Acid, Beta-Glucan, Papain, Lactic Acid/Glycolic Acid Copolymer, Palmitoyl Sh-Octapeptide-24 Amide, Palmitoyl Sh-Tripeptide-5 Norisoleucyl Sh-Nonapeptide-1, Elaeis Guineensis Oil, Gossypium Herbaceum Seed Oil, Linum Usitatissimum Seed Oil, Bidens Pilosa Extract, Tocopherol, Sodium Bisulfite, Tocopheryl Acetate, Ascorbic Acid, Retinyl Palmitate, Xanthan Gum, Polyisobutene, Polymethyl Methacrylate, Polyvinyl Alcohol, Polysorbate 20, Disodium EDTA, 1,2-Hexanediol, Carbomer, Algin, Sodium Hydroxide, Parfum, Phenoxyethanol, Caprylyl Glycol, Chlorphenesin, Pentylene Glycol

C13-15 Alkane

Caprylic/Capric Triglyceride

Dicaprylyl Carbonate

Ethyl Macadamiate

Behenyl Alcohol

Butylene Glycol

Silybum Marianum Seed Oil

Lactobacillus/Coconut Fruit Juice Ferment Filtrate

Lecithin

Bakuchiol

Hydrogenated Lecithin

Allantoin

Glycine Soja Oil

Hexylene Glycol

Boerhavia Diffusa Root Extract

Glycine Soja Sterols

Citric Acid

Sodium Phytate

Malic Acid

Ethylhexylglycerin

Water, Niacinamide, Glycerin, Tranexamic Acid, C13-15 Alkane, Caprylic/Capric Triglyceride, Dicaprylyl Carbonate, Ethyl Macadamiate, Behenyl Alcohol, Glyceryl Stearate, Butylene Glycol, Silybum Marianum Seed Oil, Tocopherol, Lactobacillus/Coconut Fruit Juice Ferment Filtrate, Lecithin, Bakuchiol, Xanthan Gum, Caprylyl Glycol, Hydrogenated Lecithin, Allantoin, Glycine Soja Oil, Hexylene Glycol, Boerhavia Diffusa Root Extract, Glycine Soja Sterols, Citric Acid, Sodium Phytate, Malic Acid, Phenoxyethanol, Ethylhexylglycerin

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Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Caprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created.

Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin.

Because it is not a free-fatty acid, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on).

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Glyceryl Stearate is made by reacting glycerin with stearic acid (typically sourced from plant oils like palm or coconut). It's an emulsifier, emollient, and mild occlusive.

Emulsifiers help ingredients like oil and water stay mixed so your formula stays nicely blended and uniform in texture.

This ingredient is typically used in concentrations between 1-10%. Studies have found it to be non-sensitizing, non-phototoxic, and non-photoallergenic.

A close cousin of this ingredient is Glyceryl Stearate SE ("self-emulsifying"). This just has a small amount of sodium or potassium stearate added so it can emulsify without a co-emulsifier.

Since this ingredient is an ester of a C18 fatty acid, it may not be fungal acne safe. The Malassezia yeast can potentially metabolize within the C11-C24 range.

Fun fact: The human body also creates Glyceryl Stearate naturally.

Niacinamide is a multitasking form of vitamin B3 that strengthens the skin barrier, reduces pores and dark spots, regulates oil, and improves signs of aging.

And the best part? It's gentle and well-tolerated by most skin types, including sensitive and reactive skin.

You might have heard of "niacin flush", or the reddening of skin that causes itchiness. Niacinamide has not been found to cause this.

In very rare cases, some individuals may not be able to tolerate niacinamide at all or experience an allergic reaction to it.

If you are experiencing flaking, irritation, and dryness with this ingredient, be sure to double check all your products as this ingredient can be found in all categories of skincare.

When incorporating niacinamide into your routine, look out for concentration amounts. Typically, 5% niacinamide provides benefits such as fading dark spots. However, if you have sensitive skin, it is better to begin with a smaller concentration.

When you apply niacinamide to your skin, your body converts it into nicotinamide adenine dinucleotide (NAD). NAD is an essential coenzyme that is already found in your cells as "fuel" and powers countless biological processes.

In your skin, NAD helps repair cell damage, produce new healthy cells, support collagen production, strengthen the skin barrier, and fight environmental stressors (like UV and pollution).

Our natural NAD levels start to decline with age, leading to slower skin repair, visible aging, and a weaker skin barrier. By providing your skin niacinamide, you're recharging your skin's NAD levels. This leads to stronger, healthier, and younger looking skin.

Another name for vitamin B3 is nicotinamide. This vitamin is water-soluble and our bodies don't store it. We obtain Vitamin B3 from either food or skincare. Meat, fish, wheat, yeast, and leafy greens contain vitamin B3.

The type of niacinamide used in skincare is synthetically created.

Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).

It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.

On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.

Another perk of this ingredient is that it stays functional across a wide pH range (3-10).

You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.

Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.

Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.

Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.

Tocopherol is a fat-soluble antioxidant known as Vitamin E.

You'll find this ingredient in the vast majority of skincare (for good reason). It works to neutralize free radicals, or unstable molecules generated by UV exposure, pollution, and other environmental stressors, before they can cause oxidative damage to your skin cells.

Topically applied tocopherol has been shown to protect against UV damage by ramping up the skin's own natural defense enzymes.

It also acts as a skin conditioning agent; some studies show that regular topical use can improve the skin's water-binding capacity over 2-4 weeks.

This ingredient is especially loved for being a team player. When combined with Vitamin C, the photoprotective effect of both ingredients roughly doubles and the combo also helps reduce UV-induced DNA damage.

This ingredient has some brightening potential but it's more of a prevention ingredient than spot-fader. Cell studies show it can slow down melanin production but it's worth noting that it's not the most powerful brightener out there.

In formulations, it also serves as a stabilizer that helps protect other oxidation-prone ingredients from degrading.

Concentrations usually range from 0.1-1% in most leave-on products.

Tranexamic Acid (TXA) is a synthetic lysine derivative that is becoming one of the most exciting brightening ingredients in skincare.

Originally used in medicine as an anti-hemorrhagic agent, its skin brightening potential was discovered by accident; patients taking it orally started noticing their melasma was fading.

Unlike most brighteners that target tyrosinase (the enzyme that synthesizes melanin), TXA works further upstream. It basically blocks your cells from receiving the signal to produce pigment.

This makes it one of the rare actives that works on three pathways at once:

This makes it effective for treating melasma, post-inflammatory hyperpigmentation (PIH), and sun-induced dark spots.

The most effective cosmetic concentration sits between 2-5% and going higher doesn't boost results.

Side effects are generally mild; occasional irritation, flaking, or dryness have been reported at the start of use. Overall, this ingredient is pretty well tolerated, even by sensitive skin types.

Another perk of this ingredient is that it does not cause photosensitivity, so it's safe to use in the AM and PM.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.

On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.

Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.

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