Peptide Skincare & BeautySkin science and ingredient guides

Ingredient or product comparison

AHK-Cu GHK-Cu Protocol Hair Research: Treatment Comparison

GHK-Cu + Microneedling 1.5mm needle depth, monthly 2% GHK-Cu topical 28.4 hairs/cm² +19% mean diameter Most robust clinical evidence. Ideal for vertex thinning and early-stage AGA AHK-Cu + GHK-Cu Combination 1.0mm needle depth, biweekly 1% AHK-Cu / 1% GHK-Cu t

This source-based comparison does not add ratings or recommend a winner.

  • GHK-Cu + Microneedling
  • 1.5mm needle depth, monthly
  • 2% GHK-Cu topical
  • 28.4 hairs/cm²
  • +19% mean diameter
  • Most robust clinical evidence. Ideal for vertex thinning and early-stage AGA
  • AHK-Cu + GHK-Cu Combination
  • 1.0mm needle depth, biweekly
  • 1% AHK-Cu / 1% GHK-Cu topical
  • 18–22 hairs/cm² (estimated from pilot data)
  • +15–17% mean diameter
  • Synergistic mechanism. Preferred when targeting both keratinocyte proliferation and angiogenesis
  • Topical GHK-Cu Alone (No Needling)
  • Twice-daily application
  • 3% GHK-Cu topical
  • 4–7 hairs/cm²
  • +5–8% mean diameter
  • Poor bioavailability without penetration enhancement. Not recommended as standalone
  • Oral Copper Supplementation
  • Oral tablet (2mg elemental copper)
  • N/A
  • No measurable follicular effect
  • No change
  • Systemically absorbed copper does not concentrate in follicular tissue. Ineffective for hair regrowth