Dr. Sheth's Centella & Niacinamide Sunscreen SPF50 Versus The Derma Co Skin Renew Barrier Repair Peptide Moisturizer

Dr. Sheth's Centella & Niacinamide Sunscreen SPF50 Versus The Derma Co Skin Renew Barrier Repair Peptide Moisturizer Detailed comparison of Dr. Sheth's Centella & Niacinamide Sunscreen SPF50 versus The Derma Co Skin Renew Barrier Repair Peptide Moisturizer. This hybrid sunscreen covers the full UV range and blocks ~98% of UVB at SPF 50. This barrier-repair moisturizer is formulated around Niacinamide and Ceramide NP to strengthen the skin barrier and soften the look of wrinkles. Cyclopentasiloxane Dimethicone/Vinyl Dimethicone Crosspolymer Ethylhexyl Methoxycinnamate Caprylyl Methicone PEG-12 Dimethicone/PPG-20 Crosspolymer C12-15 Alkyl Benzoate Zinc Oxide Triethoxycaprylylsilane Diethylhexyl Butamido Triazone Diethylamino Hydroxybenzoyl Hexyl Benzoate Niacinamide Tapioca Starch Polymethylsilsesquioxane Titanium Dioxide Alumina Simethicone Bis-Ethylhexyloxyphenol Methoxyphenyl Triazine Dicaprylyl Carbonate Centella Asiatica Extract Diethylhexyl Syringylidenemalonate Caprylic/Capric Triglyceride Cyclopentasiloxane, Dimethicone/Vinyl Dimethicone Crosspolymer, Ethylhexyl Methoxycinnamate, Caprylyl Methicone, PEG-12 Dimethicone/PPG-20 Crosspolymer, C12-15 Alkyl Benzoate, Zinc Oxide, Triethoxycaprylylsilane, Diethylhexyl Butamido Triazone, Diethylamino Hydroxybenzoyl Hexyl Benzoate, Niacinamide, Tapioca Starch, Polymethylsilsesquioxane, Titanium Dioxide, Alumina, Simethicone, Bis-Ethylhexyloxyphenol Methoxyphenyl Triazine, Dicaprylyl Carbonate, Centella Asiatica Extract, Diethylhexyl Syringylidenemalonate, Caprylic/Capric Triglyceride Water Propanediol Coco-Caprylate/Caprate Cetearyl Alcohol Betaine Neopentyl Glycol Diheptanoate Isododecane Squalane 3-O-Ethyl Ascorbic Acid Ceramide NP PEG-7 Glyceryl Cocoate Phenoxyethanol Ethylhexylglycerin Glyceryl Stearate Palmitoyl Tripeptide-5 Polyacrylate-13 Polyisobutene Polysorbate 20 Glyceryl Stearate Citrate Xylitylglucoside Anhydroxylitol Xylitol Sodium Hyaluronate Allantoin Acrylates/C10-30 Alkyl Acrylate Crosspolymer Triethanolamine Sodium Gluconate Water, Propanediol, Coco-Caprylate/Caprate, Cetearyl Alcohol, Niacinamide, Betaine, Cyclopentasiloxane, Neopentyl Glycol Diheptanoate, Isododecane, Squalane, 3-O-Ethyl Ascorbic Acid, Ceramide NP, PEG-7 Glyceryl Cocoate, Phenoxyethanol, Ethylhexylglycerin, Glyceryl Stearate, Palmitoyl Tripeptide-5, Polyacrylate-13, Polyisobutene, Polysorbate 20, Glyceryl Stearate Citrate, Centella Asiatica Extract, Xylitylglucoside, Anhydroxylitol, Xylitol, Sodium Hyaluronate, Allantoin, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Triethanolamine, Sodium Gluconate Be the first to review These ingredients are found in both products. Ingredients higher up in an ingredient list are typically present in a larger amount. Centella Asiatica Extract (Centella) is one of the most researched botanical extracts in skincare with decades of studies backing its effects on inflammation, collagen, and the skin barrier. That research keeps pointing back to the same four triterpenoid saponins: Asiaticoside, Madecassoside, Asiatic Acid, and Madecassic Acid. These compounds allow centella to dial back inflammation, encourage the skin to build and hold onto collagen, support the barrier and hydration, and bring solid antioxidant activity to protect against signs of aging. Centella also carries a nice supporting cast of Vitamin A, vitamin C, several B vitamins, and amino acids. Put it all together and you get an ingredient that soothes, hydrates, and protects, all at once. Most of centella's magic comes from the four big compounds (Asiaticoside, Madecassoside, Asiatic Acid, and Madecassic Acid). These are the actives doing the heavy lifting in almost every centella study. Here is the short version of what they do in the skin: So it is not just soothing for the sake of soothing. Centella calms the skin AND helps it rebuild. Just FYI, not all centella on an ingredient list is the same. What you are getting actually depends on the extract: Fun fact on the ratios: the leaves tend to be richest in Madecassoside and Asiaticoside, and lower in the two acids. The exact amounts shift with where the plant is grown and how it is processed. This means purity really does vary brand to brand. Centella is one of the most easygoing actives out there. It layers well with basically everything: niacinamide, hyaluronic acid, peptides, and vitamin C, and also pairs nicely with stronger actives like retinoids and exfoliating acids where it can help take the edge off irritation. On the safety side, centella and its triterpenes are classified as weak sensitizers, meaning allergic reactions are possible but uncommon. Patch tests at 1% and 5% came back negative in test panels, and creams at typical use levels did not cause allergic reactions across large groups of people. But as with any new active, a patch test is still a smart move for very reactive skin. Centella is widely used because it is effective at low percentages. For context, human safety testing found no meaningful irritation from creams containing centella extract at everyday use levels (the tested amounts were well under 1%). The irritancy threshold in animal testing was also above 30% (so real-world formulas sit far below anything concerning). In collagen lab studies, higher concentrations drove more collagen synthesis, so serums built around centella tend to feature it more prominently. Bottom line: you will find centella working nicely anywhere from a fraction of a percent up to hero-ingredient levels depending on whether it is a supporting soother or the main event. Fun fact: Centella has been used as a medi