DRMTLGY Peptide Night Cream Versus Paula's Choice Clinical Ultra-Rich Moisturizer

DRMTLGY Peptide Night Cream Versus Paula's Choice Clinical Ultra-Rich Moisturizer Detailed comparison of DRMTLGY Peptide Night Cream versus Paula's Choice Clinical Ultra-Rich Moisturizer. This anti-aging night moisturizer is formulated around Palmitoyl Tripeptide-1 and Palmitoyl Tripeptide-5 to soften the look of wrinkles. This barrier-repair moisturizer is formulated around Butyrospermum Parkii Butter Unsaponifiables and Ceramide NP to strengthen the skin barrier and hydrate skin. Water Glyceryl Stearate Propanediol C12-15 Alkyl Benzoate Glycerin Isopropyl Palmitate Undecane Butyrospermum Parkii Butter Caprylic/Capric Triglyceride Cetyl Alcohol Dimethicone PEG-100 Stearate Palmitoyl Dipeptide-5 Diaminobutyroyl Hydroxythreonine Palmitoyl Tripeptide-1 Palmitoyl Tripeptide-5 Palmitoyl Tetrapeptide-7 Trifluoroacetyl Tripeptide-2 Tetradecyl Aminobutyroylvalylaminobutyric Urea Trifluoroacetate Ceramide NP Ceramide AP Ceramide EOP Phytosphingosine Cholesterol Tridecane Allantoin Tocopherol Glycol Distearate Potassium Cetyl Phosphate Butylene Glycol Ethylhexylglycerin Acrylates/C10-30 Alkyl Acrylate Crosspolymer Carbomer Polysorbate 20 Dextran Magnesium Chloride Phenoxyethanol Disodium EDTA Sodium Hydroxide Sodium Lauroyl Lactylate Xanthan Gum Water, Glyceryl Stearate, Propanediol, C12-15 Alkyl Benzoate, Glycerin, Isopropyl Palmitate, Undecane, Butyrospermum Parkii Butter, Caprylic/Capric Triglyceride, Cetyl Alcohol, Dimethicone, PEG-100 Stearate, Palmitoyl Dipeptide-5 Diaminobutyroyl Hydroxythreonine, Palmitoyl Tripeptide-1, Palmitoyl Tripeptide-5, Palmitoyl Tetrapeptide-7, Trifluoroacetyl Tripeptide-2, Tetradecyl Aminobutyroylvalylaminobutyric Urea Trifluoroacetate, Ceramide NP, Ceramide AP, Ceramide EOP, Phytosphingosine, Cholesterol, Tridecane, Allantoin, Tocopherol, Glycol Distearate, Potassium Cetyl Phosphate, Butylene Glycol, Ethylhexylglycerin, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Carbomer, Polysorbate 20, Dextran, Magnesium Chloride, Phenoxyethanol, Disodium EDTA, Sodium Hydroxide, Sodium Lauroyl Lactylate, Xanthan Gum Butyrospermum Parkii Butter Unsaponifiables Glyceryl Stearate Se Olea Europaea Fruit Oil Stearic Acid Mangifera Indica Seed Butter Cocos Nucifera Fruit Extract Sphingolipids Phospholipids Squalene Simmondsia Chinensis Seed Oil Persea Gratissima Oil Glycine Soja Oil Oryza Sativa Bran Extract Avena Sativa Kernel Extract Panthenol Ascorbyl Palmitate Beta-Sitosterol Hydrogenated Vegetable Glycerides Citrate Propylene Glycol Water, Butyrospermum Parkii Butter Unsaponifiables, Caprylic/Capric Triglyceride, Glyceryl Stearate Se, Olea Europaea Fruit Oil, Dimethicone, Stearic Acid, Glyceryl Stearate, Mangifera Indica Seed Butter, Cetyl Alcohol, Cocos Nucifera Fruit Extract, Ceramide NP, Ceramide AP, Ceramide EOP, Sphingolipids, Phospholipids, Phytosphingosine, Squalene, Cholesterol, Tocopherol, Simmondsia Chinensis Seed Oil, Persea Gratissima Oil, Glycine Soja Oil, Oryza Sativa Bran Extract, Avena Sativa Kernel Extract, Glycerin, Panthenol, Ascorbyl Palmitate, Beta-Sitosterol, Hydrogenated Vegetable Glycerides Citrate, Propylene Glycol, Sodium Lauroyl Lactylate, Xanthan Gum, Carbomer, Disodium EDTA, Ethylhexylglycerin, Phenoxyethanol Be the first to review These ingredients are found in both products. Ingredients higher up in an ingredient list are typically present in a larger amount. Caprylic/Capric Triglyceride (aka MCT Oil) is a lightweight emollient, solvent, and texture enhancer. It is considered a skin-softener by helping to prevent moisture loss. Though it behaves like an oil, it is not technically one due to its chemical composition. One perk of this ingredient is that it is very stable, resistant to oxidation, and unlikely to go rancid. In practice, that translates to a long shelf life and a consistently elegant skin feel. While there is an assumption Caprylic Triglyceride can clog pores due to it being derived from coconut oil, there is no research supporting this. Just patch test if you have concerns. Fractionated coconut oil and MCT Oil are both listed as Caprylic/Capric Triglyceride according to INCI. This is because INCI names are based on the ingredient’s final chemical composition and not its marketing name or source. This ingredient is treated as the gold standard fungal acne safe oil. Even though it is coconut derived, the problematic lauric acid is stripped out. This leaves just caprylic (C8) and capric (C10) acid. These chain lengths actually trend antifungal; a 2020 study found caprylic acid was enough to disrupt Malassezia furfur cell membrane, with a caprylic acid derivative damaging membrane structures at concentrations as low as 0.2%. Carbomer is a synthetic thickening and gelling agent. It's basically the ingredient that gives a lot of serums, gels, creams, and sunscreens their smooth, non-sticky texture. Although legally permitted at very high levels, carbomers are normally used at concentrations below 1%. It also needs to be neutralized to actually thicken, and because it is a large molecule, it doesn't really penetrate the skin barrier. Allergy-wise, the risk is very low. Clinical studies show carbomers have low potential for skin irritation/sensitization even at concentrations up to 100%. A 2024 UK study patch-tested 1,302 patients and found true allergy to the parent group of carbomer to be rare with no confirmed relevant reactions. Ceramide AP is is a skin-identical lipid that mimics what your skin already makes naturally. Ceramides help maintain epidermal integrity and barrier function. You'll often see this ingredient paired with other ceramides (like ceramide NP), cholesterol, or fatty acids because this combination best mimics the natural lipid mix your skin already has. The skin's ability to produce ceramides gets disrupted in skin conditions like eczema. This in turn weakens the skin barrier and applying ceramides topically has been shown to replenish what's been lost to restore barrier function. Most of the studies with Ceramide AP test it as part of a multi-ceramide complex; studies reinforce ceramide AP's role in rebalancing ceramides in skin and improving skin hydration. Ceramide EOP is formally known as Ceramide 1. It is naturally found in skin and part o