Paula's Choice Barrier Repair Advanced Moisturizer Versus DRMTLGY Peptide Night Cream

Paula's Choice Barrier Repair Advanced Moisturizer Versus DRMTLGY Peptide Night Cream Detailed comparison of Paula's Choice Barrier Repair Advanced Moisturizer US versus DRMTLGY Peptide Night Cream. This barrier-repair moisturizer is formulated around Squalane and Ceramide NP to strengthen the skin barrier and hydrate skin. This anti-aging night moisturizer is formulated around Palmitoyl Tripeptide-1 and Palmitoyl Tripeptide-5 to soften the look of wrinkles. Water Dicaprylyl Carbonate Ethylhexyl Stearate Glycerin Cocoglycerides Squalane Sodium Polyacrylate Butyrospermum Parkii Butter Ceramide NP Ceramide AP Ceramide As Ceramide Ns Ceramide EOP Sodium Hyaluronate Adenosine Palmitoyl Tripeptide-5 Citrullus Lanatus Seed Oil Glyceryl Stearate Caprylyl Glycol Hydroxyacetophenone Sodium Stearoyl Glutamate Hexylene Glycol Tocopherol 2,3-Butanediol Xanthan Gum Ethylhexylglycerin Sodium Phytate Sodium PCA Urea Hydrogenated Lecithin Trehalose Polyquaternium-51 Triacetin Cholesterol Phenoxyethanol Water, Dicaprylyl Carbonate, Ethylhexyl Stearate, Glycerin, Cocoglycerides, Squalane, Sodium Polyacrylate, Butyrospermum Parkii Butter, Ceramide NP, Ceramide AP, Ceramide As, Ceramide Ns, Ceramide EOP, Sodium Hyaluronate, Adenosine, Palmitoyl Tripeptide-5, Citrullus Lanatus Seed Oil, Glyceryl Stearate, Caprylyl Glycol, Hydroxyacetophenone, Sodium Stearoyl Glutamate, Hexylene Glycol, Tocopherol, 2,3-Butanediol, Xanthan Gum, Ethylhexylglycerin, Sodium Phytate, Sodium PCA, Urea, Hydrogenated Lecithin, Trehalose, Polyquaternium-51, Triacetin, Cholesterol, Phenoxyethanol Propanediol C12-15 Alkyl Benzoate Isopropyl Palmitate Undecane Caprylic/Capric Triglyceride Cetyl Alcohol Dimethicone PEG-100 Stearate Palmitoyl Dipeptide-5 Diaminobutyroyl Hydroxythreonine Palmitoyl Tripeptide-1 Palmitoyl Tetrapeptide-7 Trifluoroacetyl Tripeptide-2 Tetradecyl Aminobutyroylvalylaminobutyric Urea Trifluoroacetate Phytosphingosine Tridecane Allantoin Glycol Distearate Potassium Cetyl Phosphate Butylene Glycol Acrylates/C10-30 Alkyl Acrylate Crosspolymer Carbomer Polysorbate 20 Dextran Magnesium Chloride Disodium EDTA Sodium Hydroxide Sodium Lauroyl Lactylate Water, Glyceryl Stearate, Propanediol, C12-15 Alkyl Benzoate, Glycerin, Isopropyl Palmitate, Undecane, Butyrospermum Parkii Butter, Caprylic/Capric Triglyceride, Cetyl Alcohol, Dimethicone, PEG-100 Stearate, Palmitoyl Dipeptide-5 Diaminobutyroyl Hydroxythreonine, Palmitoyl Tripeptide-1, Palmitoyl Tripeptide-5, Palmitoyl Tetrapeptide-7, Trifluoroacetyl Tripeptide-2, Tetradecyl Aminobutyroylvalylaminobutyric Urea Trifluoroacetate, Ceramide NP, Ceramide AP, Ceramide EOP, Phytosphingosine, Cholesterol, Tridecane, Allantoin, Tocopherol, Glycol Distearate, Potassium Cetyl Phosphate, Butylene Glycol, Ethylhexylglycerin, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Carbomer, Polysorbate 20, Dextran, Magnesium Chloride, Phenoxyethanol, Disodium EDTA, Sodium Hydroxide, Sodium Lauroyl Lactylate, Xanthan Gum Be the first to review These ingredients are found in both products. Ingredients higher up in an ingredient list are typically present in a larger amount. This ingredient is also known as shea butter. It is a plant-derived extract from the nuts of the Africa shea tree and one of the most well-studied emollients. Because it has a high concentration of fatty acids (primarily oleic, stearic, and linoleic) it is able to form a protective barrier on the skin's surface. This helps seal in moisture and prevents transepidermal water loss (TEWL). In vitro research found an increase in skin hydration by 58% and a decrease in TEWL by 37.8% after 24 hours of applying this ingredient (pretty impressive for a single ingredient!). Besides hydration, shea butter also contains triterpenes that have anti-inflammatory potential. In particule, lupeol cinnamate has shown the highest anti-inflammatory activity in vivo. Shea butter also contains vitamins A and E which may contribute to antioxidant activity. While Shea Butter has an SPF rating of about 3-4, it is not a sunscreen replacement. This ingredient may not be fungal acne safe because its fatty acids fall within the C11-C24 range that the Malassezia yeast can metabolize. Ceramide AP is is a skin-identical lipid that mimics what your skin already makes naturally. Ceramides help maintain epidermal integrity and barrier function. You'll often see this ingredient paired with other ceramides (like ceramide NP), cholesterol, or fatty acids because this combination best mimics the natural lipid mix your skin already has. The skin's ability to produce ceramides gets disrupted in skin conditions like eczema. This in turn weakens the skin barrier and applying ceramides topically has been shown to replenish what's been lost to restore barrier function. Most of the studies with Ceramide AP test it as part of a multi-ceramide complex; studies reinforce ceramide AP's role in rebalancing ceramides in skin and improving skin hydration. Ceramide EOP is formally known as Ceramide 1. It is naturally found in skin and part of the intercellular "mortar" holding everything together in your outermost layer. EOP stands for a linked Ester fatty acid, a linked Omega hydroxy fatty acid, and the Phytosphingosine base. What makes Ceramide EOP special is its ultra-long fatty acid chain; this unique structure allows it to bridge the lipid layers in your skin barrier to prevent water loss (something no other ceramide can do). Low levels of Ceramide EOP have been found in people with eczema and psoriasis. Using it together with other ceramides, cholesterol, and linoleic acid have been shown to meaningfully improve hydration and reduce water loss. In one clinical study, a regimen using Ceramide EOP, NP, and AP led to significant symptom improvements in patients with eczema, psoriasis, and dry skin in just 4 weeks. You'll usually see concentrations between 0.1-0.5% in formulations. Overall, this is a well-tolerated and safe ingredient for cosmetic use. Ceramide NP (for