Peptide Skincare & BeautySkin science and ingredient guides

Ingredient or product comparison

One Thing Peptide Retinal Serum Versus MediCube Retinol-Some 1.9% NMN Boosting Serum

One Thing Peptide Retinal Serum Versus MediCube Retinol-Some 1.9% NMN Boosting Serum Detailed comparison of One Thing Peptide Retinal Serum versus MediCube Retinol-Some 1.9% NMN Boosting Serum. This anti-aging serum is formulated around Niacinamide and Palmito

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One Thing Peptide Retinal Serum Versus MediCube Retinol-Some 1.9% NMN Boosting Serum Detailed comparison of One Thing Peptide Retinal Serum versus MediCube Retinol-Some 1.9% NMN Boosting Serum. This anti-aging serum is formulated around Niacinamide and Palmitoyl Tripeptide-5 to soften the look of wrinkles and refine skin texture. This anti-aging serum is formulated around Niacinamide and Retinol to soften the look of wrinkles and refine skin texture. Water Butylene Glycol Niacinamide Caprylic/Capric Triglyceride Dipropylene Glycol Cetyl Ethylhexanoate Propanediol Vinyldimethicone Glycerin Glyceryl Polymethacrylate 1,2-Hexanediol Betaine C14-22 Alcohols Cetearyl Olivate Glyceryl Stearate Hydroxyacetophenone Propylene Glycol Sorbitan Olivate Acrylates/C10-30 Alkyl Acrylate Crosspolymer Tromethamine C12-20 Alkyl Glucoside Ethylhexylglycerin Polyacrylate Crosspolymer-6 Adenosine Hydrolyzed Gardenia Florida Extract Hydrolyzed Malt Extract Hydrolyzed Viola Tricolor Extract Sodium Polyacrylate Dextrin Disodium EDTA Sodium Polyacryloyldimethyl Taurate Gardenia Florida Fruit Extract Hyaluronic Acid Hydrolyzed Hyaluronic Acid Sodium Hyaluronate Hydrogenated Polydecene Carbomer Hydrogenated Lecithin Polyglyceryl-10 Oleate Sodium Lactate Trideceth-10 Palmitoyl Tripeptide-5 Polysorbate 20 Sodium Ascorbyl Phosphate Palmitoyl Tripeptide-1 Palmitoyl Tetrapeptide-7 Copper Tripeptide-1 Palmitoyl Pentapeptide-4 Acetyl Hexapeptide-8 Macadamia Ternifolia Seed Oil Phosphatidylcholine Cholesterol Phytosteryl/Behenyl/Octyldodecyl Lauroyl Glutamate Aluminum/Magnesium Hydroxide Stearate Brassica Campestris Sterols Retinal Potassium Cetyl Phosphate Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate Water, Butylene Glycol, Niacinamide, Caprylic/Capric Triglyceride, Dipropylene Glycol, Cetyl Ethylhexanoate, Propanediol, Vinyldimethicone, Glycerin, Glyceryl Polymethacrylate, 1,2-Hexanediol, Betaine, C14-22 Alcohols, Cetearyl Olivate, Glyceryl Stearate, Hydroxyacetophenone, Propylene Glycol, Sorbitan Olivate, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Tromethamine, C12-20 Alkyl Glucoside, Ethylhexylglycerin, Polyacrylate Crosspolymer-6, Adenosine, Hydrolyzed Gardenia Florida Extract, Hydrolyzed Malt Extract, Hydrolyzed Viola Tricolor Extract, Sodium Polyacrylate, Dextrin, Disodium EDTA, Sodium Polyacryloyldimethyl Taurate, Gardenia Florida Fruit Extract, Hyaluronic Acid, Hydrolyzed Hyaluronic Acid, Sodium Hyaluronate, Hydrogenated Polydecene, Carbomer, Hydrogenated Lecithin, Polyglyceryl-10 Oleate, Sodium Lactate, Trideceth-10, Palmitoyl Tripeptide-5, Polysorbate 20, Sodium Ascorbyl Phosphate, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Copper Tripeptide-1, Palmitoyl Pentapeptide-4, Acetyl Hexapeptide-8, Macadamia Ternifolia Seed Oil, Phosphatidylcholine, Cholesterol, Phytosteryl/Behenyl/Octyldodecyl Lauroyl Glutamate, Aluminum/Magnesium Hydroxide Stearate, Brassica Campestris Sterols, Retinal, Potassium Cetyl Phosphate, Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate Glycereth-26 Retinol Polyglyceryl-10 Laurate Tris(Tetramethylhydroxypiperidinol)Citrate Glyceryl Citrate/Lactate/Linoleate/Oleate Elaeis Guineensis Oil Ammonium Acryloyldimethyltaurate/Vp Copolymer Aluminum Starch Octenylsuccinate Squalane Polyquaternium-51 Tocopherol Panthenol Allantoin Bifida Ferment Lysate Lactobacillus Ferment Lysate Lactococcus Ferment Lysate Centella Asiatica Leaf Extract Asiaticoside Asiatic Acid Madecassic Acid Bet These ingredients are found in both products. Ingredients higher up in an ingredient list are typically present in a larger amount. 1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse. It is a: Humectant, drawing moisture into the skin Emollient, helping to soften skin Solvent, dispersing and stabilizing formulas Preservative booster, enhancing the antimicrobial activity of other preservatives Acetyl Hexapeptide-8 (also known as Argireline) is a synthetic hexapeptide that is often called a "topical Botox alternative". It works by mimicking how Botox relaxes muscles; it interferes with the signaling process that tells your facial muscles to contract. This can help soften expression lines like forehead wrinkles or crow's feet over time. The comparison to Botox does have limits because the molecule is water-loving and relatively large. Acetyl Hexapeptide-8 has a hard time absorbing deeply enough through the skin's outer barrier to actually reach the muscles. So whether it truly works the way Botox does at a biological level is still up for debate, but early clinical outcomes are fairly encouraging. A 12 week human study of a multi-ingredient regimen containing this ingredient saw: While some studies have observed improvements in wrinkle appearance, it is important to note that more consistent results are seen in multi-ingredient formulations (vs just Acetyl Hexapeptide-8 alone). Some research studies also used higher concentrations (up to 10%) while this ingredient is usually found in concentrations up to 0.005% in leave-on formulations. Adenosine is a purine nucleoside that your body already makes in every cell. In skincare, it acts mainly as a skin conditioning and anti-aging agent. The way it works is fairly well mapped out: Your skin has cells called fibroblasts that build collagen (the stuff that keeps skin firm and smooth). Adenosine basically flips a switch on these cells that tells them to get to work making more collagen and other proteins. These cells slow down on their own as skin ages, so Adenosine helps give them a little nudge to keep going. The clinical backing is pretty solid too. A blind, randomized, placebo-controlled trial of 126 women aged 45-65 tested a 0.1% cream twice daily and found real improvements in crow's feet and frown lines using a precise 3D skin-mapping technique; these changes showed up by week 3 and held at 2 months. A later study using Adenosine-loaded dissolving microneedle patches reported gains in wrinkle depth, dermal density, elasticity, and hydration. On concentrations, South Korea's Ministry of Food and Drug Safety has set 0.04% as the approved functional anti-wrinkle level. You'll typically see this ingredient used somewhere in the 0.04-0.1% range since it works at low doses. This ingredient has been found safe for cosmetics with the data showing no irritation or sensitization. Overall, this is a great ingredient for any anti-aging routine and has no photosensitizing effect, so it