Peptide Skincare & BeautySkin science and ingredient guides

Ingredient or product comparison

One Thing Peptide Retinal Serum Versus Theramid A-Retinoate

One Thing Peptide Retinal Serum Versus Theramid A-Retinoate Detailed comparison of One Thing Peptide Retinal Serum versus Theramid A-Retinoate. This anti-aging serum is formulated around Niacinamide and Palmitoyl Tripeptide-5 to soften the look of wrinkles and

This source-based comparison does not add ratings or recommend a winner.

One Thing Peptide Retinal Serum Versus Theramid A-Retinoate Detailed comparison of One Thing Peptide Retinal Serum versus Theramid A-Retinoate. This anti-aging serum is formulated around Niacinamide and Palmitoyl Tripeptide-5 to soften the look of wrinkles and refine skin texture. This anti-aging serum is formulated around Retinal and Retinyl Retinoate to soften the look of wrinkles and refine skin texture. Water Butylene Glycol Niacinamide Caprylic/Capric Triglyceride Dipropylene Glycol Cetyl Ethylhexanoate Propanediol Vinyldimethicone Glycerin Glyceryl Polymethacrylate 1,2-Hexanediol Betaine C14-22 Alcohols Cetearyl Olivate Glyceryl Stearate Hydroxyacetophenone Propylene Glycol Sorbitan Olivate Acrylates/C10-30 Alkyl Acrylate Crosspolymer Tromethamine C12-20 Alkyl Glucoside Ethylhexylglycerin Polyacrylate Crosspolymer-6 Adenosine Hydrolyzed Gardenia Florida Extract Hydrolyzed Malt Extract Hydrolyzed Viola Tricolor Extract Sodium Polyacrylate Dextrin Disodium EDTA Sodium Polyacryloyldimethyl Taurate Gardenia Florida Fruit Extract Hyaluronic Acid Hydrolyzed Hyaluronic Acid Sodium Hyaluronate Hydrogenated Polydecene Carbomer Hydrogenated Lecithin Polyglyceryl-10 Oleate Sodium Lactate Trideceth-10 Palmitoyl Tripeptide-5 Polysorbate 20 Sodium Ascorbyl Phosphate Palmitoyl Tripeptide-1 Palmitoyl Tetrapeptide-7 Copper Tripeptide-1 Palmitoyl Pentapeptide-4 Acetyl Hexapeptide-8 Macadamia Ternifolia Seed Oil Phosphatidylcholine Cholesterol Phytosteryl/Behenyl/Octyldodecyl Lauroyl Glutamate Aluminum/Magnesium Hydroxide Stearate Brassica Campestris Sterols Retinal Potassium Cetyl Phosphate Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate Water, Butylene Glycol, Niacinamide, Caprylic/Capric Triglyceride, Dipropylene Glycol, Cetyl Ethylhexanoate, Propanediol, Vinyldimethicone, Glycerin, Glyceryl Polymethacrylate, 1,2-Hexanediol, Betaine, C14-22 Alcohols, Cetearyl Olivate, Glyceryl Stearate, Hydroxyacetophenone, Propylene Glycol, Sorbitan Olivate, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Tromethamine, C12-20 Alkyl Glucoside, Ethylhexylglycerin, Polyacrylate Crosspolymer-6, Adenosine, Hydrolyzed Gardenia Florida Extract, Hydrolyzed Malt Extract, Hydrolyzed Viola Tricolor Extract, Sodium Polyacrylate, Dextrin, Disodium EDTA, Sodium Polyacryloyldimethyl Taurate, Gardenia Florida Fruit Extract, Hyaluronic Acid, Hydrolyzed Hyaluronic Acid, Sodium Hyaluronate, Hydrogenated Polydecene, Carbomer, Hydrogenated Lecithin, Polyglyceryl-10 Oleate, Sodium Lactate, Trideceth-10, Palmitoyl Tripeptide-5, Polysorbate 20, Sodium Ascorbyl Phosphate, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Copper Tripeptide-1, Palmitoyl Pentapeptide-4, Acetyl Hexapeptide-8, Macadamia Ternifolia Seed Oil, Phosphatidylcholine, Cholesterol, Phytosteryl/Behenyl/Octyldodecyl Lauroyl Glutamate, Aluminum/Magnesium Hydroxide Stearate, Brassica Campestris Sterols, Retinal, Potassium Cetyl Phosphate, Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate Coco-Caprylate Dimethicone Tribehenin PEG-20 Esters Silica Coco-Caprylate/Caprate Panthenol Cetearyl Alcohol PPG-13-Decyltetradeceth-24 Retinyl Retinoate Sodium Retinoyl Hyaluronate Jojoba Esters Helianthus Annuus Seed Wax Dimethicone/Vinyl Dimethicone Crosspolymer Mannitol Isopropyl Lauroyl Sarcosinate Cetyl Alcohol Acacia Decurrens Flower Wax Polyglycerin-3 Diethylhexyl Syringylidenemalonate Benzotriazolyl Dodecyl P-Cresol Xanthan Gum To Be the first to review These ingredients are found in both products. Ingredients higher up in an ingredient list are typically present in a larger amount. Betaine is a humectant. Like hyaluronic acid, it helps attract and retain moisture in the skin. It’s known for being gentle and for helping the skin maintain balanced hydration. Betaine is mainly used to improve hydration and support calmer skin. It helps skin cells regulate water balance because it functions as an osmolyte. Some studies suggest betaine may support making skin tone more even. Fun fact: Betaine naturally exists in the skin and the body. In cosmetic products, it can be either plant-derived (most commonly from sugar beets) or synthetically produced for consistency and stability. Betaine is also known as trimethylglycine. Butylene Glycol (or BG) is used within cosmetic products for a few different reasons: Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients. Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness. Caprylic/Capric Triglyceride (aka MCT Oil) is a lightweight emollient, solvent, and texture enhancer. It is considered a skin-softener by helping to prevent moisture loss. Though it behaves like an oil, it is not technically one due to its chemical composition. One perk of this ingredient is that it is very stable, resistant to oxidation, and unlikely to go rancid. In practice, that translates to a long shelf life and a consistently elegant skin feel. While there is an assumption Caprylic Triglyceride can clog pores due to it being derived from coconut oil, there is no research supporting this. Just patch test if you have concerns. Fractionated coconut oil and MCT Oil are both listed as Caprylic/Capric Triglyceride according to INCI. This is because INCI names are based on the ingredient’s final chemical composition and not its marketing name or source. This ingredient is treated as the gold standard fungal acne safe oil. Even though it is coconut derived, the problematic lauric acid is stripped out. This leaves just caprylic (C8) and capric (C10) acid. These chain lengths actually trend antifungal; a 2020 study found caprylic acid was enough to disrupt Malassezia furfur cell membrane, with a caprylic acid derivative damaging membrane structures at concentrations as low as 0.2%. Carbomer is a synthetic thickening and gelling agent. It's basically the ingredient that gives a lot of serums, gels, creams, and sunscreens their smooth, non-sticky texture. Although legally permitted at very high levels, carbomers are normally used at concentrations below 1%. It also needs to be neutralized to actually thicken, and because it is a large molecule, it doesn't really penetrate the skin barrier. Allergy-wise, the risk is very low. Clinical studies show carbomers have low potential for skin irritation/sensitization even at concentrations up to 1