Peptide Skincare & BeautySkin science and ingredient guides

Ingredient or product comparison

Principia Sérum Facial PM-10 Versus The Ordinary "Buffet"

Principia Sérum Facial PM-10 Versus The Ordinary "Buffet" Detailed comparison of Principia Sérum Facial PM-10 versus The Ordinary "Buffet". This anti-aging serum is formulated around Palmitoyl Tripeptide-1 and Palmitoyl Tetrapeptide-7 to soften the look of wri

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Principia Sérum Facial PM-10 Versus The Ordinary "Buffet" Detailed comparison of Principia Sérum Facial PM-10 versus The Ordinary "Buffet". This anti-aging serum is formulated around Palmitoyl Tripeptide-1 and Palmitoyl Tetrapeptide-7 to soften the look of wrinkles and refine skin texture. This anti-aging serum is formulated around Lactococcus Ferment Lysate and Acetyl Hexapeptide-8 to soften the look of wrinkles. Water Glycerin Sodium Hyaluronate Butylene Glycol Carbomer Polysorbate 20 Palmitoyl Tripeptide-1 Palmitoyl Tetrapeptide-7 Hydroxypropyl Cyclodextrin Palmitoyl Tripeptide-38 Propylene Glycol Phenoxyethanol Caprylyl Glycol Xanthan Gum Disodium EDTA Sodium Hydroxide Water, Glycerin, Sodium Hyaluronate, Butylene Glycol, Carbomer, Polysorbate 20, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Hydroxypropyl Cyclodextrin, Palmitoyl Tripeptide-38, Propylene Glycol, Phenoxyethanol, Caprylyl Glycol, Xanthan Gum, Disodium EDTA, Sodium Hydroxide Lactococcus Ferment Lysate Acetyl Hexapeptide-8 Pentapeptide-18 Dipeptide Diaminobutyroyl Benzylamide Diacetate Acetylarginyltryptophyl Diphenylglycine Sodium Hyaluronate Crosspolymer Allantoin Glycine Alanine Serine Valine Isoleucine Proline Threonine Histidine Phenylalanine Arginine Aspartic Acid Trehalose Fructose Glucose Maltose Urea Sodium PCA PCA Sodium Lactate Citric Acid Sodium Chloride Pentylene Glycol Acacia Senegal Gum PPG-26-Buteth-26 PEG-40 Hydrogenated Castor Oil Trisodium Ethylenediamine Disuccinate Ethoxydiglycol Sodium Benzoate Ethylhexylglycerin Chlorphenesin Water, Glycerin, Lactococcus Ferment Lysate, Acetyl Hexapeptide-8, Pentapeptide-18, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Palmitoyl Tripeptide-38, Dipeptide Diaminobutyroyl Benzylamide Diacetate, Acetylarginyltryptophyl Diphenylglycine, Sodium Hyaluronate Crosspolymer, Sodium Hyaluronate, Allantoin, Glycine, Alanine, Serine, Valine, Isoleucine, Proline, Threonine, Histidine, Phenylalanine, Arginine, Aspartic Acid, Trehalose, Fructose, Glucose, Maltose, Urea, Sodium PCA, PCA, Sodium Lactate, Citric Acid, Hydroxypropyl Cyclodextrin, Sodium Chloride, Sodium Hydroxide, Butylene Glycol, Pentylene Glycol, Acacia Senegal Gum, Xanthan Gum, Carbomer, Polysorbate 20, PPG-26-Buteth-26, PEG-40 Hydrogenated Castor Oil, Trisodium Ethylenediamine Disuccinate, Ethoxydiglycol, Sodium Benzoate, Caprylyl Glycol, Ethylhexylglycerin, Phenoxyethanol, Chlorphenesin These ingredients are found in both products. Ingredients higher up in an ingredient list are typically present in a larger amount. Butylene Glycol (or BG) is used within cosmetic products for a few different reasons: Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients. Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness. Caprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created. Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin. Because it is not a free-fatty acid, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on). Carbomer is a synthetic thickening and gelling agent. It's basically the ingredient that gives a lot of serums, gels, creams, and sunscreens their smooth, non-sticky texture. Although legally permitted at very high levels, carbomers are normally used at concentrations below 1%. It also needs to be neutralized to actually thicken, and because it is a large molecule, it doesn't really penetrate the skin barrier. Allergy-wise, the risk is very low. Clinical studies show carbomers have low potential for skin irritation/sensitization even at concentrations up to 100%. A 2024 UK study patch-tested 1,302 patients and found true allergy to the parent group of carbomer to be rare with no confirmed relevant reactions. Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum. Topically, glycerin does several things at once: Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3. Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin. This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products. Just know very high concentrations (>40%) can feel tacky in low humidity. Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine. This ingredient is used in skincare as a delivery system. It works by "encapsulating" active ingredients with its unique ring shape that is water-loving on the outside and oil-loving on the inside. This improves the stability and absorption of the product into the skin. According to a manufacturer, it also offer some moisturizing effects. Palmitoyl Tetrapeptide-7 (formerly Palmitoyl Tetrapeptide-3) is a synthetic peptide. Its main job is to fight what researchers call "inflammaging". "Inflammaging"