Peptide Skincare & BeautySkin science and ingredient guides

Ingredient or product comparison

Versed On The Rise Firming Serum Versus Peter Thomas Roth Peptide 21 Wrinkle Resist Serum

Versed On The Rise Firming Serum Versus Peter Thomas Roth Peptide 21 Wrinkle Resist Serum Detailed comparison of Versed On The Rise Firming Serum versus Peter Thomas Roth Peptide 21 Wrinkle Resist Serum. This anti-aging serum is formulated around Resveratrol a

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Versed On The Rise Firming Serum Versus Peter Thomas Roth Peptide 21 Wrinkle Resist Serum Detailed comparison of Versed On The Rise Firming Serum versus Peter Thomas Roth Peptide 21 Wrinkle Resist Serum. This anti-aging serum is formulated around Resveratrol and Palmitoyl Tripeptide-1 to soften the look of wrinkles and refine skin texture. This anti-aging serum is formulated around Tripeptide-10 Citrulline and Acetyl Octapeptide-3 to soften the look of wrinkles. Water Propylene Glycol Glycerin Propanediol Butylene Glycol Resveratrol Palmitoyl Tripeptide-1 Palmitoyl Tetrapeptide-7 Retinyl Palmitate Tocopheryl Acetate Tocopherol Sodium Hyaluronate Citric Acid Phenoxyethanol PEG-40 Hydrogenated Castor Oil Polyacrylate Crosspolymer-6 Sodium Ascorbyl Phosphate Xanthan Gum Trisodium Ethylenediamine Disuccinate Ceramide AP 1,2-Hexanediol Carbomer Sodium Metabisulfite Polysorbate 20 Sodium Lactate Water, Propylene Glycol, Glycerin, Propanediol, Butylene Glycol, Resveratrol, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Retinyl Palmitate, Tocopheryl Acetate, Tocopherol, Sodium Hyaluronate, Citric Acid, Phenoxyethanol, PEG-40 Hydrogenated Castor Oil, Polyacrylate Crosspolymer-6, Sodium Ascorbyl Phosphate, Xanthan Gum, Trisodium Ethylenediamine Disuccinate, Ceramide AP, 1,2-Hexanediol, Carbomer, Sodium Metabisulfite, Polysorbate 20, Sodium Lactate Rosa Centifolia Flower Water Isopropyl Myristate Squalane Mannitol Natto Gum Tripeptide-10 Citrulline Acetyl Octapeptide-3 Palmitoyl Hexapeptide-12 Acetyl Tetrapeptide-11 Acetyl Hexapeptide-8 Acetyl Hexapeptide-1 Palmitoyl Oligopeptide Acetyl Tetrapeptide-9 Acetyl Tetrapeptide-2 Tripeptide-1 Hexapeptide-11 Dipeptide Diaminobutyroyl Benzylamide Diacetate Palmitoyl Tripeptide-5 Trifluoroacetyl Tripeptide-2 Sodium Polyglutamate Ascorbic Acid Hydrolyzed Soy Protein Hydrolyzed Wheat Protein Lecithin Pseudoalteromonas Ferment Extract Acrylates Copolymer Magnesium Chloride Dimethyl Isosorbide Acrylates/C10-30 Alkyl Acrylate Crosspolymer Leuconostoc/Radish Root Ferment Filtrate PEG-8 Dimethicone Disodium Phosphate Dextran Tetradecyl Aminobutyroylvalylaminobutyric Urea Trifluoroacetate Triethanolamine Sodium Phosphate Octyldodecanol Silica Sodium Propoxyhydroxypropyl Thiosulfate Silica Sodium Hydroxide Caprylyl Glycol Potassium Sorbate Sodium Benzoate Water, Glycerin, Rosa Centifolia Flower Water, Isopropyl Myristate, Squalane, Mannitol, Butylene Glycol, Natto Gum, Tripeptide-10 Citrulline, Acetyl Octapeptide-3, Palmitoyl Hexapeptide-12, Acetyl Tetrapeptide-11, Acetyl Hexapeptide-8, Acetyl Hexapeptide-1, Palmitoyl Oligopeptide, Acetyl Tetrapeptide-9, Acetyl Tetrapeptide-2, Tripeptide-1, Palmitoyl Tetrapeptide-7, Hexapeptide-11, Dipeptide Diaminobutyroyl Benzylamide Diacetate, Palmitoyl Tripeptide-5, Trifluoroacetyl Tripeptide-2, Palmitoyl Tripeptide-1, Sodium Polyglutamate, Sodium Hyaluronate, Tocopheryl Acetate, Retinyl Palmitate, Ascorbic Acid, Hydrolyzed Soy Protein, Hydrolyzed Wheat Protein, Lecithin, Pseudoalteromonas Ferment Extract, Acrylates Copolymer, Magnesium Chloride, Polysorbate 20, Dimethyl Isosorbide, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Leuconostoc/Radish Root Ferment Filtrate, PEG-8 Dimethicone, Disodium Phosphate, Carbomer, Dextran, Sodium Lactate, Tetradecyl Aminobutyroylvalylaminobutyric Urea Trifluoroacetate, Xanthan Gum, Triethanolamine, Sodium Phosphate, Octyldodecanol, Silica, Sodium Propoxyhydroxypropyl Thiosulfate Silica, Sodium Hydroxide, Ca These ingredients are found in both products. Ingredients higher up in an ingredient list are typically present in a larger amount. Butylene Glycol (or BG) is used within cosmetic products for a few different reasons: Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients. Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness. Carbomer is a synthetic thickening and gelling agent. It's basically the ingredient that gives a lot of serums, gels, creams, and sunscreens their smooth, non-sticky texture. Although legally permitted at very high levels, carbomers are normally used at concentrations below 1%. It also needs to be neutralized to actually thicken, and because it is a large molecule, it doesn't really penetrate the skin barrier. Allergy-wise, the risk is very low. Clinical studies show carbomers have low potential for skin irritation/sensitization even at concentrations up to 100%. A 2024 UK study patch-tested 1,302 patients and found true allergy to the parent group of carbomer to be rare with no confirmed relevant reactions. Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum. Topically, glycerin does several things at once: Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3. Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin. This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products. Just know very high concentrations (>40%) can feel tacky in low humidity. Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine. Palmitoyl Tetrapeptide-7 (formerly Palmitoyl Tetrapeptide-3) is a synthetic peptide. Its main job is to fight what researchers call "inflammaging". "Inflammaging" is the slow, low-grade chronic inflammation that quietly breaks down collagen as we age. This ingredient calms down a specific inflammation signal in your skin cells (called IL-6). When left unchecked, this signal triggers enzymes that break down collagen and elastin. Clinical testing showed statistically significant improvements in: Studies also found the more of this ingredient used, the more your skin produces Collagen I, fibronectin, and hyaluronic acid. You'll likely see this ingredient paired with Palmitoyl Tripeptide-1 in the well-known Matrixyl 3000 complex for enhanced anti-aging effects. A 3% concentration applied twice daily for two months showed meaningful skin rejuvenation result