Skin science article
Allies of Skin Peptides & Antioxidants Advanced Firming Daily Treatment Versus Drunk Elephant Protini Polypeptide Cream
Allies of Skin Peptides & Antioxidants Advanced Firming Daily Treatment Versus Drunk Elephant Protini Polypeptide Cream This anti-aging moisturizer is formulated around Ferulic Acid and Ceramide NP to soften the look of wrinkles and strengthen the skin barrier
Allies of Skin Peptides & Antioxidants Advanced Firming Daily Treatment Versus Drunk Elephant Protini Polypeptide Cream
This anti-aging moisturizer is formulated around Ferulic Acid and Ceramide NP to soften the look of wrinkles and strengthen the skin barrier.
This anti-aging moisturizer is formulated around Sclerocarya Birrea Seed Oil and Sh-Oligopeptide-1 to soften the look of wrinkles and hydrate skin.
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Caprylic/Capric Triglyceride
Isononyl Isononanoate
Glycerin
C12-15 Alkyl Benzoate
Polysorbate 60
Pentaerythrityl Tetraisostearate
Cetearyl Olivate
Mannitol
Polyacrylate Crosspolymer-6
Polyglyceryl-10 Oleate
Euterpe Oleracea Fruit Oil
Rubus Idaeus Seed Oil
Ascorbyl Palmitate
Lactobacillus Ferment
Saccharomyces/Xylinum/Black Tea Ferment
Camellia Sinensis Leaf Extract
Ferulic Acid
Ceramide NP
Caffeine
Honey
Phospholipids
Sphingolipids
Hyaluronic Acid
Bisabolol
Allantoin
Epigallocatechin Gallate
Glutathione
Ergothioneine
Dunaliella Salina Extract
Waltheria Indica Leaf Extract
Lecithin
Astaxanthin
Tocopherol
Biotin
Benzimidazole Diamond Amidoethyl Urea Carbamoyl Propyl Polymethylsilsesquioxane
Teprenone
Sorbitan Olivate
Lonicera Caprifolium Flower Extract
Palmitoyl Tripeptide-5
Palmitoyl Dipeptide-5 Diaminobutyroyl Hydroxythreonine
Palmitoyl Dipeptide-5 Diaminohydroxybutyrate
Palmitoyl Tripeptide-38
Dimethyl Isosorbide
Tetrahydrodiferuloylmethane
Palmitoyl Tripeptide-8
Acetyl Tetrapeptide-40
Tetrahydrodemethoxydiferuloylmethane
Tetrahydrobisdemethoxydiferuloylmethane
Dextrin
Hydroxypropyl Cyclodextrin
Dextran
Lonicera Japonica Flower Extract
Leuconostoc/Radish Root Ferment Filtrate
Sodium Gluconate
Hydroxyethylcellulose
Citric Acid
Potassium Sorbate
Sodium Hydroxide
Sodium Citrate
Caprylyl Glycol
Sodium Benzoate
Sodium Dehydroacetate
Hydrogenated Palm Glycerides Citrate
T-Butyl Alcohol
Polysorbate 20
Butylene Glycol
Phenoxyethanol
Water, Caprylic/Capric Triglyceride, Isononyl Isononanoate, Glycerin, C12-15 Alkyl Benzoate, Polysorbate 60, Pentaerythrityl Tetraisostearate, Cetearyl Olivate, Mannitol, Polyacrylate Crosspolymer-6, Polyglyceryl-10 Oleate, Euterpe Oleracea Fruit Oil, Rubus Idaeus Seed Oil, Ascorbyl Palmitate, Lactobacillus Ferment, Saccharomyces/Xylinum/Black Tea Ferment, Camellia Sinensis Leaf Extract, Ferulic Acid, Ceramide NP, Caffeine, Honey, Phospholipids, Sphingolipids, Hyaluronic Acid, Bisabolol, Allantoin, Epigallocatechin Gallate, Glutathione, Ergothioneine, Dunaliella Salina Extract, Waltheria Indica Leaf Extract, Lecithin, Astaxanthin, Tocopherol, Biotin, Benzimidazole Diamond Amidoethyl Urea Carbamoyl Propyl Polymethylsilsesquioxane, Teprenone, Sorbitan Olivate, Lonicera Caprifolium Flower Extract, Palmitoyl Tripeptide-5, Palmitoyl Dipeptide-5 Diaminobutyroyl Hydroxythreonine, Palmitoyl Dipeptide-5 Diaminohydroxybutyrate, Palmitoyl Tripeptide-38, Dimethyl Isosorbide, Tetrahydrodiferuloylmethane, Palmitoyl Tripeptide-8, Acetyl Tetrapeptide-40, Tetrahydrodemethoxydiferuloylmethane, Tetrahydrobisdemethoxydiferuloylmethane, Dextrin, Hydroxypropyl Cyclodextrin, Dextran, Lonicera Japonica Flower Extract, Leuconostoc/Radish Root Ferment Filtrate, Sodium Gluconate, Hydroxyethylcellulose, Citric Acid, Potassium Sorbate, Sodium Hydroxide, Sodium Citrate, Caprylyl Glycol, Sodium Benzoate, Sodium Dehydroacetate, Hydrogenated Palm Glycerides Citrate, T-Butyl Alcohol, Polysorbate 20, Butylene Glycol, Phenoxyethanol
Dicaprylyl Carbonate
Cetearyl Alcohol
Sclerocarya Birrea Seed Oil
Bacillus/Folic Acid Ferment Filtrate Extract
Nymphaea Alba Root Extract
Sh-Oligopeptide-1
Sh-Oligopeptide-2
Sh-Polypeptide-1
Sh-Polypeptide-9
Sh-Polypeptide-11
Copper Palmitoyl Heptapeptide-14
Heptapeptide-15 Palmitate
Palmitoyl Tetrapeptide-7
Palmitoyl Tripeptide-1
Alanine
Arginine
Glycine
Histidine
Isoleucine
Phenylalanine
Proline
Serine
Threonine
Valine
Acetyl Glutamine
Coconut Alkanes
Coco-Caprylate/Caprate
Sodium Hyaluronate
Aspartic Acid
Linoleic Acid
Linolenic Acid
Polyvinyl Alcohol
Sodium Lactate
Sodium PCA
PCA
Sorbitan Isostearate
Carbomer
Lactic Acid/Glycolic Acid Copolymer
Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer
Xanthan Gum
Isomalt
1,2-Hexanediol
Chlorphenesin
Phenylpropanol
Glyceryl Caprylate
Symphytum Officinale Callus Culture Extract
Water, Dicaprylyl Carbonate, Glycerin, Cetearyl Alcohol, Cetearyl Olivate, Sorbitan Olivate, Sclerocarya Birrea Seed Oil, Bacillus/Folic Acid Ferment Filtrate Extract, Nymphaea Alba Root Extract, Sh-Oligopeptide-1, Sh-Oligopeptide-2, Sh-Polypeptide-1, Sh-Polypeptide-9, Sh-Polypeptide-11, Copper Palmitoyl Heptapeptide-14, Heptapeptide-15 Palmitate, Palmitoyl Tetrapeptide-7, Palmitoyl Tripeptide-1, Alanine, Arginine, Glycine, Histidine, Isoleucine, Phenylalanine, Proline, Serine, Threonine, Valine, Acetyl Glutamine, Coconut Alkanes, Coco-Caprylate/Caprate, Sodium Hyaluronate, Aspartic Acid, Linoleic Acid, Linolenic Acid, Lecithin, Butylene Glycol, Polyvinyl Alcohol, Sodium Lactate, Sodium PCA, PCA, Sorbitan Isostearate, Carbomer, Polysorbate 20, Polysorbate 60, Lactic Acid/Glycolic Acid Copolymer, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Xanthan Gum, Isomalt, 1,2-Hexanediol, Caprylyl Glycol, Chlorphenesin, Phenoxyethanol, Tocopherol, Sodium Benzoate, Phenylpropanol, Glyceryl Caprylate, Symphytum Officinale Callus Culture Extract
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Alternatives
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:
Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.
Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.
Caprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created.
Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin.
Because it is not a free-fatty acid, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on).
Cetearyl Olivate is a plant-derived emulsifier and texture enhancer. It helps keep the oil and water phases from separating so your formulas stay stable.
You'll likely see it combined with Sorbitan Olivate (together sold as the trade name Olivem 1000). This combination generates a liquid crystal structure that closely resemble the lipid organization of the stratum corneum.
These "skin-like" liquid crystals improve skin barrier integrity and promote the delivery of actives into the skin.
This ingredient is well-tolerated and has no significant sensitization data.
Because it is derived from the fatty acids in olive oil, this ingredient may not be fungal acne safe.
Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Lecithin is a term for a group of substances found in the cell membranes of plants, animals, and humans. They are made up of phospholipids.
Thanks to its amphiphilic structure (water-loving head and oil-loving tail), it is a true multitasker:
It plays well with most ingredients and is typically used at 0.1-1%. However, concentrations up to 50% have been reported in moisturizers.
Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).
It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.
On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.
Another perk of this ingredient is that it stays functional across a wide pH range (3-10).
You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.
Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.
Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.
Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.
Polysorbate 20 is a gentle, water-soluble emulsifier and mild surfactant. It stops oil and water from separating to keep your formulas blended and stable.
It also acts as a mild penetration enhancer by helping active ingredients absorb slightly better.
The common safety discussion around this ingredient involves a manufacturing byproduct called 1,4-dioxane.
Trace amounts can form during production but the EU's Scientific Committee on Consumer Safety has concluded that levels at/below 10 ppm in finished products are safe (commercial products consistently fall within acceptable margins).
True allergic reactions are uncommon and the CIR Expert Panel has confirmed this ingredient to be safe as used in cosmetics.
Because it is derived from lauric acid, it may not be fungal acne safe.
Polysorbate 60 is used to help stabilize products. It is a surfactant and emulsifier. These properties help keep ingredients together in a product. Surfactants help reduce surface tension between ingredients with different states, such as liquids and solids. Emulsifiers help prevent oils and waters from separating.
Polysorbate 60 is sorbitol-based and created from the ethoxylation of sorbitan. Ethoxylation is a chemical reaction used to add ethylene oxide. Sorbitan is a the dehydrated version of sorbitol, a sugar found in fruits.
In this case, the 60 comes from reacting 60 units of ethylene oxide with sorbitan.
Polysorbates are commonly used in medicine and foods.
Sodium Benzoate is a preservative. It's used in both cosmetic and food products to inhibit the growth of mold and bacteria. It is typically produced synthetically.
Both the US FDA and EU Health Committee have approved the use of sodium benzoate. In the US, levels of 0.1% (of the total product) are allowed.
Sodium benzoate works as a preservative by inhibiting the growth of bacteria inside of cells. It prevents the cell from fermenting a type of sugar using an enzyme called phosphofructokinase.
It is the salt of benzoic acid. Foods containing sodium benzoate include soda, salad dressings, condiments, fruit juices, wines, and snack foods.
Studies for using ascorbic acid and sodium benzoate in cosmetics are lacking, especially in skincare routines with multiple steps.
We always recommend speaking with a professional, such as a dermatologist, if you have any concerns.
Sorbitan Olivate is created from the fatty acids in olive oil and sorbitol.
This ingredient is an oil in water emulsifier. It helps stabilize a product by preventing oils and waters from separating. Sorbitan Olivate also helps hydrate the skin.
This ingredient is also known as part of Olivem 1000, with Cetearyl Olivate being the other part.
According to a manufacturer, this ingredient helps preserve the natural microbiome of skin. Having a healthy microbiome helps keep our skin healthy and protects against harmful bacteria.
Please note, having a healthy microbiome is different from fungal acne; a healthy microbiome includes small amounts of yeast that normally live on your skin without causing problems.
Fungal acne happens when one type of yeast (Malassezia) grows out of control. This is usually because it's feeding on certain oils or fatty acids. Due to the olive oil base, this ingredient may not be fungal acne safe.
Tocopherol is a fat-soluble antioxidant known as Vitamin E.
You'll find this ingredient in the vast majority of skincare (for good reason). It works to neutralize free radicals, or unstable molecules generated by UV exposure, pollution, and other environmental stressors, before they can cause oxidative damage to your skin cells.
Topically applied tocopherol has been shown to protect against UV damage by ramping up the skin's own natural defense enzymes.
It also acts as a skin conditioning agent; some studies show that regular topical use can improve the skin's water-binding capacity over 2-4 weeks.
This ingredient is especially loved for being a team player. When combined with Vitamin C, the photoprotective effect of both ingredients roughly doubles and the combo also helps reduce UV-induced DNA damage.
This ingredient has some brightening potential but it's more of a prevention ingredient than spot-fader. Cell studies show it can slow down melanin production but it's worth noting that it's not the most powerful brightener out there.
In formulations, it also serves as a stabilizer that helps protect other oxidation-prone ingredients from degrading.
Concentrations usually range from 0.1-1% in most leave-on products.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!