Skin science article
Dr. Emi Arpa Barrier Boost Versus Allies of Skin Peptides & Antioxidants Advanced Firming Daily Treatment
Dr. Emi Arpa Barrier Boost Versus Allies of Skin Peptides & Antioxidants Advanced Firming Daily Treatment This barrier-repair moisturizer is formulated around Azelaic Acid and Bifida Ferment Lysate to strengthen the skin barrier and calm redness. This anti-agi
Dr. Emi Arpa Barrier Boost Versus Allies of Skin Peptides & Antioxidants Advanced Firming Daily Treatment
This barrier-repair moisturizer is formulated around Azelaic Acid and Bifida Ferment Lysate to strengthen the skin barrier and calm redness.
This anti-aging moisturizer is formulated around Ferulic Acid and Ceramide NP to soften the look of wrinkles and strengthen the skin barrier.
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Azelaic Acid
Bifida Ferment Lysate
C15-19 Alkane
Glycerin
Squalane
Lactococcus Ferment Lysate
Sodium Acrylates Copolymer
Inulin
Propanediol
Butylene Glycol
Prunus Amygdalus Dulcis Oil
Myristyl Myristate
Phytosphingosine
Cholesterol
Ceramide AP
Ceramide NP
Ceramide EOP
Alpha-Glucan Oligosaccharide
Carnosine
Copper Tripeptide-1
Acetyl Dipeptide-1 Cetyl Ester
Baicalin
Ectoin
Tremella Fuciformis Sporocarp Extract
Hydrolyzed Jojoba Esters
Aloe Barbadensis Leaf Juice
Tocopherol
Lecithin
Arginine
Lactic Acid
Acetic Acid
Helianthus Annuus Seed Oil
Xanthan Gum
Hydroxyethylcellulose
Carbomer
Sodium Lauroyl Lactylate
Sodium Chloride
Sorbitan Laurate
Caprylyl Glycol
Glyceryl Caprylate
Ethylhexylglycerin
Sodium Phytate
Phenylpropanol
Levulinic Acid
Sodium Levulinate
Sodium Benzoate
Phenoxyethanol
Water, Azelaic Acid, Bifida Ferment Lysate, C15-19 Alkane, Glycerin, Squalane, Lactococcus Ferment Lysate, Sodium Acrylates Copolymer, Inulin, Propanediol, Butylene Glycol, Prunus Amygdalus Dulcis Oil, Myristyl Myristate, Phytosphingosine, Cholesterol, Ceramide AP, Ceramide NP, Ceramide EOP, Alpha-Glucan Oligosaccharide, Carnosine, Copper Tripeptide-1, Acetyl Dipeptide-1 Cetyl Ester, Baicalin, Ectoin, Tremella Fuciformis Sporocarp Extract, Hydrolyzed Jojoba Esters, Aloe Barbadensis Leaf Juice, Tocopherol, Lecithin, Arginine, Lactic Acid, Acetic Acid, Helianthus Annuus Seed Oil, Xanthan Gum, Hydroxyethylcellulose, Carbomer, Sodium Lauroyl Lactylate, Sodium Chloride, Sorbitan Laurate, Caprylyl Glycol, Glyceryl Caprylate, Ethylhexylglycerin, Sodium Phytate, Phenylpropanol, Levulinic Acid, Sodium Levulinate, Sodium Benzoate, Phenoxyethanol
Caprylic/Capric Triglyceride
Isononyl Isononanoate
C12-15 Alkyl Benzoate
Polysorbate 60
Pentaerythrityl Tetraisostearate
Cetearyl Olivate
Mannitol
Polyacrylate Crosspolymer-6
Polyglyceryl-10 Oleate
Euterpe Oleracea Fruit Oil
Rubus Idaeus Seed Oil
Ascorbyl Palmitate
Lactobacillus Ferment
Saccharomyces/Xylinum/Black Tea Ferment
Camellia Sinensis Leaf Extract
Ferulic Acid
Caffeine
Honey
Phospholipids
Sphingolipids
Hyaluronic Acid
Bisabolol
Allantoin
Epigallocatechin Gallate
Glutathione
Ergothioneine
Dunaliella Salina Extract
Waltheria Indica Leaf Extract
Astaxanthin
Biotin
Benzimidazole Diamond Amidoethyl Urea Carbamoyl Propyl Polymethylsilsesquioxane
Teprenone
Sorbitan Olivate
Lonicera Caprifolium Flower Extract
Palmitoyl Tripeptide-5
Palmitoyl Dipeptide-5 Diaminobutyroyl Hydroxythreonine
Palmitoyl Dipeptide-5 Diaminohydroxybutyrate
Palmitoyl Tripeptide-38
Dimethyl Isosorbide
Tetrahydrodiferuloylmethane
Palmitoyl Tripeptide-8
Acetyl Tetrapeptide-40
Tetrahydrodemethoxydiferuloylmethane
Tetrahydrobisdemethoxydiferuloylmethane
Dextrin
Hydroxypropyl Cyclodextrin
Dextran
Lonicera Japonica Flower Extract
Leuconostoc/Radish Root Ferment Filtrate
Sodium Gluconate
Citric Acid
Potassium Sorbate
Sodium Hydroxide
Sodium Citrate
Sodium Dehydroacetate
Hydrogenated Palm Glycerides Citrate
T-Butyl Alcohol
Polysorbate 20
Water, Caprylic/Capric Triglyceride, Isononyl Isononanoate, Glycerin, C12-15 Alkyl Benzoate, Polysorbate 60, Pentaerythrityl Tetraisostearate, Cetearyl Olivate, Mannitol, Polyacrylate Crosspolymer-6, Polyglyceryl-10 Oleate, Euterpe Oleracea Fruit Oil, Rubus Idaeus Seed Oil, Ascorbyl Palmitate, Lactobacillus Ferment, Saccharomyces/Xylinum/Black Tea Ferment, Camellia Sinensis Leaf Extract, Ferulic Acid, Ceramide NP, Caffeine, Honey, Phospholipids, Sphingolipids, Hyaluronic Acid, Bisabolol, Allantoin, Epigallocatechin Gallate, Glutathione, Ergothioneine, Dunaliella Salina Extract, Waltheria Indica Leaf Extract, Lecithin, Astaxanthin, Tocopherol, Biotin, Benzimidazole Diamond Amidoethyl Urea Carbamoyl Propyl Polymethylsilsesquioxane, Teprenone, Sorbitan Olivate, Lonicera Caprifolium Flower Extract, Palmitoyl Tripeptide-5, Palmitoyl Dipeptide-5 Diaminobutyroyl Hydroxythreonine, Palmitoyl Dipeptide-5 Diaminohydroxybutyrate, Palmitoyl Tripeptide-38, Dimethyl Isosorbide, Tetrahydrodiferuloylmethane, Palmitoyl Tripeptide-8, Acetyl Tetrapeptide-40, Tetrahydrodemethoxydiferuloylmethane, Tetrahydrobisdemethoxydiferuloylmethane, Dextrin, Hydroxypropyl Cyclodextrin, Dextran, Lonicera Japonica Flower Extract, Leuconostoc/Radish Root Ferment Filtrate, Sodium Gluconate, Hydroxyethylcellulose, Citric Acid, Potassium Sorbate, Sodium Hydroxide, Sodium Citrate, Caprylyl Glycol, Sodium Benzoate, Sodium Dehydroacetate, Hydrogenated Palm Glycerides Citrate, T-Butyl Alcohol, Polysorbate 20, Butylene Glycol, Phenoxyethanol
Alternatives
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:
Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.
Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.
Caprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created.
Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin.
Because it is not a free-fatty acid, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on).
Ceramide NP (formerly known as Ceramide 3) is one of the skin's naturally occurring lipids.
Since ceramides are the major lipid components of the skin, they are crucial for maintaining skin barrier and hydration. Ceramide NP most closely mirrors the dominant kind in human skin amongst ceramide subtypes.
This ceramide works by slotting into gaps within the stratum corneum's lipid matrix to limit trans-epidermal water loss (TEWL) and shield the skin against external irritants.
A study with 312 patients found that using a ceramide-containing routine for 4 weeks reduced the severity of atopic dermatitis by over 61%.
Another clinical study in subjects aged 60 and older found that a ceramide body wash and moisturizer improved skin dryness and itchy skin in 15 days.
Overall, ceramides are considered non-irritating and safety tests have found little to no observable adverse effects from using this ingredient.
Ceramide NP is usually sourced from plants (like soybean or rice bran), or produced synthetically.
Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Hydroxyethylcellulose is used to improve the texture of products. It is created from a chemical reaction involving ethylene oxide and alkali-cellulose. Cellulose is a sugar found in plant cell walls and help give plants structure.
This ingredient helps stabilize products by preventing ingredients from separating. It can also help thicken the texture of a product.
This ingredient can also be found in pill medicines to help our bodies digest other ingredients.
Lecithin is a term for a group of substances found in the cell membranes of plants, animals, and humans. They are made up of phospholipids.
Thanks to its amphiphilic structure (water-loving head and oil-loving tail), it is a true multitasker:
It plays well with most ingredients and is typically used at 0.1-1%. However, concentrations up to 50% have been reported in moisturizers.
Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).
It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.
On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.
Another perk of this ingredient is that it stays functional across a wide pH range (3-10).
You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.
Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.
Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.
Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.
Sodium Benzoate is a preservative. It's used in both cosmetic and food products to inhibit the growth of mold and bacteria. It is typically produced synthetically.
Both the US FDA and EU Health Committee have approved the use of sodium benzoate. In the US, levels of 0.1% (of the total product) are allowed.
Sodium benzoate works as a preservative by inhibiting the growth of bacteria inside of cells. It prevents the cell from fermenting a type of sugar using an enzyme called phosphofructokinase.
It is the salt of benzoic acid. Foods containing sodium benzoate include soda, salad dressings, condiments, fruit juices, wines, and snack foods.
Studies for using ascorbic acid and sodium benzoate in cosmetics are lacking, especially in skincare routines with multiple steps.
We always recommend speaking with a professional, such as a dermatologist, if you have any concerns.
Tocopherol is a fat-soluble antioxidant known as Vitamin E.
You'll find this ingredient in the vast majority of skincare (for good reason). It works to neutralize free radicals, or unstable molecules generated by UV exposure, pollution, and other environmental stressors, before they can cause oxidative damage to your skin cells.
Topically applied tocopherol has been shown to protect against UV damage by ramping up the skin's own natural defense enzymes.
It also acts as a skin conditioning agent; some studies show that regular topical use can improve the skin's water-binding capacity over 2-4 weeks.
This ingredient is especially loved for being a team player. When combined with Vitamin C, the photoprotective effect of both ingredients roughly doubles and the combo also helps reduce UV-induced DNA damage.
This ingredient has some brightening potential but it's more of a prevention ingredient than spot-fader. Cell studies show it can slow down melanin production but it's worth noting that it's not the most powerful brightener out there.
In formulations, it also serves as a stabilizer that helps protect other oxidation-prone ingredients from degrading.
Concentrations usually range from 0.1-1% in most leave-on products.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!