Peptide Skincare & BeautySkin science and ingredient guides

Skin science article

C’est Moi Clarify Blemish Cleansing Wipes for Acne Versus First Aid Beauty Pure Skin Face Cleanser

C’est Moi Clarify Blemish Cleansing Wipes for Acne Versus First Aid Beauty Pure Skin Face Cleanser This acne treatment pad uses a pre-saturated pad with Salicylic Acid and Azelaic Acid to clear breakouts and balance excess oil. This mild cream cleanser is made

C’est Moi Clarify Blemish Cleansing Wipes for Acne Versus First Aid Beauty Pure Skin Face Cleanser

This acne treatment pad uses a pre-saturated pad with Salicylic Acid and Azelaic Acid to clear breakouts and balance excess oil.

This mild cream cleanser is made to cleanse while calming and soothing your skin.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Salicylic Acid 1%

Alcohol

Allantoin

Aloe Barbadensis Leaf Juice

Azelaic Acid

Calendula Officinalis Flower Extract

Camellia Sinensis Leaf Extract

Coco-Glucoside

Cucumis Sativus Fruit Extract

Decyl Glucoside

Dipotassium Glycyrrhizate

Ethylhexylglycerin

Glycerin

Glyceryl Oleate

Glycyrrhiza Glabra Root Extract

Lactic Acid

Phenoxyethanol

Polyglyceryl-10 Caprylate/Caprate

Polyglyceryl-4 Caprate

Potassium Sorbate

Propanediol

Pyrus Malus Fruit Extract

Salix Alba Bark Extract

Sodium Benzoate

Sodium Hydroxide

Tetrasodium Glutamate Diacetate

Vinegar

Water

Salicylic Acid 1%, Alcohol, Allantoin, Aloe Barbadensis Leaf Juice, Azelaic Acid, Calendula Officinalis Flower Extract, Camellia Sinensis Leaf Extract, Coco-Glucoside, Cucumis Sativus Fruit Extract, Decyl Glucoside, Dipotassium Glycyrrhizate, Ethylhexylglycerin, Glycerin, Glyceryl Oleate, Glycyrrhiza Glabra Root Extract, Lactic Acid, Phenoxyethanol, Polyglyceryl-10 Caprylate/Caprate, Polyglyceryl-4 Caprate, Potassium Sorbate, Propanediol, Pyrus Malus Fruit Extract, Salix Alba Bark Extract, Sodium Benzoate, Sodium Hydroxide, Tetrasodium Glutamate Diacetate, Vinegar, Water

Sodium Cocoyl Isethionate

Stearic Acid

Hydrogenated Coconut Acid

Sodium Isethionate

Stearyl Alcohol

Chrysanthemum Parthenium Extract

Tocopherol

Hydrogenated Palm Glycerides Citrate

Disodium Cocoamphodiacetate

Sodium PCA

Hydroxypropyl Methylcellulose

Sodium Chloride

Disodium EDTA

Citric Acid

Maltodextrin

Tetrasodium EDTA

Water, Sodium Cocoyl Isethionate, Glycerin, Stearic Acid, Hydrogenated Coconut Acid, Sodium Isethionate, Stearyl Alcohol, Allantoin, Chrysanthemum Parthenium Extract, Camellia Sinensis Leaf Extract, Glycyrrhiza Glabra Root Extract, Aloe Barbadensis Leaf Juice, Tocopherol, Hydrogenated Palm Glycerides Citrate, Phenoxyethanol, Disodium Cocoamphodiacetate, Sodium PCA, Hydroxypropyl Methylcellulose, Coco-Glucoside, Glyceryl Oleate, Sodium Chloride, Disodium EDTA, Citric Acid, Potassium Sorbate, Sodium Benzoate, Maltodextrin, Tetrasodium EDTA

Reviews

Be the first to review

Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Allantoin is a soothing ingredient known for its protective and moisturizing properties; it's basically a quiet workhorse ingredient you can find in a huge range of cosmetics.

Though it can be derived from the comfrey plant, allantoin is produced synthetically for cosmetic products to ensure purity.

Research shows it can encourage your skin cells to turn over and renew by stimulating keratinocyte and fibroblast proliferation.

It also has mild keratolytic properties to help loosen and shed dead skin cells without being harsh.

Studies also suggest allantoin can help calm inflammation by dialing down some of the chemical signals your skin sends out when it is irritated.

This ingredient is typically used in the 0.1-0.5% range, and the FDA recognizes it as a skin protectant in OTC products up to 2%.

Overall, allantoin is a wonderful addition to most routines; it is stable across a wide pH range (~4-8), works well with other ingredients, and is considered non-sensitizing/non-irritating.

Fun fact: Allantoin is naturally occurring in comfrey root, beets, chamomile, and wheat sprouts. Our bodies even produce it as a byproduct of uric acid metabolism.

Aloe Barbadensis Leaf Juice is the filtered, stabilized liquid pressed from the inner gel of the aloe vera leaf.

In cosmetics, it shows up as either soothing active or a water-replacement base. It is roughly 98-99% water and the last 1-2% is an interesting mix of polysaccharides, amino acids, vitamins, minerals, and enzymes.

The polysaccharides do most of the work: they bind water at the skin surface for a light, non-greasy hydration boost. And one of the polysaccharides, glycomannan, is linked to fibroblast stimulation + collagen synthesis. This is also why aloe has such a long track record in wound and burn healing.

This ingredient is also calming with anti-inflammatory and mild antimicrobial activity, making it a great pick for sensitive, irritated, or post-sun skin.

Realistic expectations matter though; the solid evidence is mostly limited to hydration, soothing, and wound support. Deeper claims about anti-aging or sun protection are not well backed, and science reviews note it does not prevent radiation-induced skin injury.

Because it plays well with almost everything, it's commonly used as a base alongside other actives like niacinamide or vitamin C.

Typical usage concentrations range from 0.5% (where hydration benefits already show up) all the way to 90%+ (where it replaces water as the main base).

The safety for this ingredient is well-establish as well. Overall, this is a great supporting ingredient for those who want a boost in hydration.

Camellia Sinensis Leaf Extract (tea extract) is one of the most well-researched plant extracts in skincare with an impressive resume.

Black tea, green tea, and oolong tea are all harvested from the Camellia Sinensis plant.

Studies show green tea extract and its catechins (like epigallocatechin gallate (EGCG)) help your skin cells product energy more efficiently and reducing the number of free-radicals that can damage your skin from the inside.

In lab-grown skin models, this translated to younger, healthier, and stronger skin.

There's also good sun protection data; researchers saw less DNA damage and redness on human skin when green tea was applied before UVB exposure. And the more they applied, the better the protection.

Needless to say, this ingredient shouldn't replace your sunscreen. But it is a great supportive ingredient that you can already find in many sunscreens and antioxidant serums.

A 2009 study found a 2% green tea lotion was effective for mild-to-moderate acne thanks to its anti-inflammatory and mild antimicrobial activity.

The quality of the extract matters a lot here:

Good extracts contain 50-90% catechins while lower quality ones are mostly there for marketing. We recommend reaching out to the brand if you have questions about the quality or source of their ingredients.

Human Repeated Insult Patch Testing showed no irritation or sensitization at use concentrations (0.86% in leave-on products and up to 30% as leaf water).

Coco-Glucoside is a surfactant, or a cleansing ingredient. It is made from glucose and coconut oil.

Surfactants help gather dirt, oil, and other pollutants from your skin to be rinsed away.

This ingredient is considered gentle and non-comedogenic. However, it may still be irritating for some.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Glyceryl Oleate is the monoester of glycerin and oleic acid. It is a skin-conditioning emollient that also helps form emulsions.

What makes glyceryl oleate special is its "re-fatting" effect.

When you wash your hair and skin with a surfactant-based cleanser, the surfactants grab onto everything. This includes your skin's natural lipids, or the fats that live in your skin barrier and sebum. Once you rinse these surfactants away, it leaves your skin feeling tight, dry, and clean (in a not-good way).

Re-fatting is essentially putting some of these lipids back. Glyceryl oleate deposits a thin layer of emollient lipids back on the skin or hair surface reduce some of the barrier damage.

Also, glyceryl oleate isn't a foreign molecule to your skin. It's chemically identical to something your skin already produces and manages naturally. This is why it tends to be well-tolerated with low risk of irritation.

Typical use levels range from 0.5-5%.

Glyceryl Oleate has a function of "perfuming" in the CosIng database. This just means that the ingredient has some scent character that can contribute to the product's overall smell.

The scent of this ingredient is described as "waxy".

As an ester of oleic acid, this ingredient may not be fungal acne safe. This is because oleic acid falls into the carbon-chain length that Malassezia can use as a substrate.

Glycyrrhiza Glabra Root Extract is an extract of the roots of Licorice. It has been found to have several benefits such as skin hydrating, conditioning, and soothing.

One component, glabridin, has extra potent antioxidant and soothing properties. It has also been found to block pigmentation from UVB rays in guinea pigs.

Licorice Root also contains a flavonoid. Flavonoids are a natural substance from in plants. Flavonoids also have antioxidant properties.

Another component, glycyrrhizin, has been found to have anti-inflammatory and antimicrobial benefits. This may make licorice root extract effective at treating acne. However, more research is needed to support this.

Liquiritin is one of the flavone compounds found in licorice. It has been found to help lighten skin by preventing tyrosinase from reacting with tyrosine. When the two react, protein is converted to melanin. Melanin is the substance in your body that gives your features pigmentation.

Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).

It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.

On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.

Another perk of this ingredient is that it stays functional across a wide pH range (3-10).

You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.

Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.

Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.

Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.

Potassium Sorbate is a preservative used to prevent yeast and mold in products. It is commonly found in both cosmetic and food products.

This ingredient comes from potassium salt derived from sorbic acid. Sorbic acid is a natural antibiotic and effective against fungus.

Both potassium sorbate and sorbic acid can be found in baked goods, cheeses, dried meats, dried fruit, ice cream, pickles, wine, yogurt, and more.

You'll often find this ingredient used with other preservatives.

Sodium Benzoate is a preservative. It's used in both cosmetic and food products to inhibit the growth of mold and bacteria. It is typically produced synthetically.

Both the US FDA and EU Health Committee have approved the use of sodium benzoate. In the US, levels of 0.1% (of the total product) are allowed.

Sodium benzoate works as a preservative by inhibiting the growth of bacteria inside of cells. It prevents the cell from fermenting a type of sugar using an enzyme called phosphofructokinase.

It is the salt of benzoic acid. Foods containing sodium benzoate include soda, salad dressings, condiments, fruit juices, wines, and snack foods.

Studies for using ascorbic acid and sodium benzoate in cosmetics are lacking, especially in skincare routines with multiple steps.

We always recommend speaking with a professional, such as a dermatologist, if you have any concerns.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

Similar Comparisons

The reference edit

Ingredients, questions
& further reading.

Connected source records selected through this article’s public topic index.

01

Formula cabinet

Ingredients & structured notes

Ingredient index

Ingredients Explained

  1. 01These ingredients are found in both products.
  2. 02Ingredients higher up in an ingredient list are typically present in a larger amount.
  3. 033-O-Ethyl Ascorbic Acid is one of the most popular "stable" vitamin C derivatives in skincare.
  4. 04Plain ascorbic acid is fantastic but notoriously fragile; it browns, oxidizes, and loses potency fast. So attaching an ethyl group to the third carbon of the molecule gives it some cool perks:
  5. 05In a formula, it does the 3 classic vitamin C jobs: it acts as an antioxidant, helps brighten skin tone by inhibiting tyrosinase, and supports collagen.
  6. 06The evidence is reasonably solid for a cosmetic ingredient; Liao and colleagues (2018) showed it's significantly more stable than ascorbic acid while still being effective.
  7. 07A 2021 study by Zerbinati and colleagues tested a serum with 30% 3-O-ethyl-l-ascorbic acid and 1% lactic acid significantly increased collagen production, reduced UVB-induced DNA damage, and decreased melanin on a reconstructed pigmented skin model.
  8. 08Typical real world usage sits around 0.5-5% (and 1-2% is common for daily serums).
  9. 09Amounts up to 30% have been shown to be non-irritating on human skin samples, but two isolated cases reported allergic contact dermatitis so a patch test is sensible if you have reactive skin.
  10. 10Citric Acid is an alpha hydroxy acid (AHA) naturally found in citrus fruits like oranges, lemons, and limes.
  11. 11Like other AHAs, citric acid can exfoliate skin by breaking down the bonds that hold dead skin cells together. This helps reveal smoother and brighter skin underneath.
  12. 12However, this exfoliating effect only happens at high concentrations (20%) which can be hard to find in cosmetic products.
  13. 13Due to this, citric acid is usually included in small amounts as a pH adjuster. This helps keep products slightly more acidic and compatible with skin's natural pH.
  14. 14In skincare formulas, citric acid can:
  15. 15While it can provide some skin benefits, research shows lactic acid and glycolic acid are generally more effective and less irritating exfoliants.
  16. 16Most citric acid used in skincare today is made by fermenting sugars (usually from molasses). This synthetic version is identical to the natural citrus form but easier to stabilize and use in formulations.
  17. 17Rosacea skin has a lower threshold for acids generally, with 62.5% of rosacea subjects in one study reacting to lactic acid in a sting test. This is why we mark citric acid as a potential rosacea trigger.
  18. 18However, this ingredient shows up as a pH adjuster or chelator at roughly 0.1-1% in many products. These low levels are unlikely to be an issue for rosacea skin and becomes a potential trigger at exfoliating concentrations (20%). Because everybody's…
  19. 19Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
  20. 20Topically, glycerin does several things at once:
Source · skinsort.com
02

Product index

Related product references

03

Comparison edit

Read side by side