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Clearstem Skincare Hydraglow Stem Cell Moisturizer Versus Paula's Choice Barrier Repair Advanced Moisturizer

Clearstem Skincare Hydraglow Stem Cell Moisturizer Versus Paula's Choice Barrier Repair Advanced Moisturizer This anti-aging moisturizer is formulated around Squalane and Bakuchiol to soften the look of wrinkles and hydrate skin. This barrier-repair moisturize

Clearstem Skincare Hydraglow Stem Cell Moisturizer Versus Paula's Choice Barrier Repair Advanced Moisturizer

This anti-aging moisturizer is formulated around Squalane and Bakuchiol to soften the look of wrinkles and hydrate skin.

This barrier-repair moisturizer is formulated around Ceramide Ag and Ceramide NP to strengthen the skin barrier and hydrate skin.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Squalane

Propanediol

Cannabis Sativa Seed Oil

Punica Granatum Seed Oil

Polyglyceryl-6 Distearate

Glycerin

Cetyl Alcohol

Raphanus Sativus Seed Extract

Bakuchiol

Aloe Barbadensis Leaf Extract

Hyaluronic Acid

Jojoba Esters

Olibanum

Camellia Sinensis Extract

Sodium Cocoyl/Stearoyl (Alanine/Arginine/Asparagine/Aspartic Acid/Glutamic Acid/Glutamine/Glycine/Histidine/Isoleucine/Leucine/Lysine/Phenylalanine/Proline/Serine/Threonine/Tyrosine/Valine)

Phenylalanine

Argania Spinosa Sprout Cell Extract

Curcuma Longa Root Extract

Tanacetum Annuum Flower Oil

Lactobacillus Ferment

Diglucosyl Gallic Acid

Thioctic Acid

Lactic Acid

Xanthan Gum

Caprylyl Glycol

Ethylhexylglycerin

Water, Squalane, Propanediol, Cannabis Sativa Seed Oil, Punica Granatum Seed Oil, Polyglyceryl-6 Distearate, Glycerin, Cetyl Alcohol, Raphanus Sativus Seed Extract, Bakuchiol, Aloe Barbadensis Leaf Extract, Hyaluronic Acid, Jojoba Esters, Olibanum, Camellia Sinensis Extract, Sodium Cocoyl/Stearoyl (Alanine/Arginine/Asparagine/Aspartic Acid/Glutamic Acid/Glutamine/Glycine/Histidine/Isoleucine/Leucine/Lysine/Phenylalanine/Proline/Serine/Threonine/Tyrosine/Valine), Phenylalanine, Argania Spinosa Sprout Cell Extract, Curcuma Longa Root Extract, Tanacetum Annuum Flower Oil, Lactobacillus Ferment, Diglucosyl Gallic Acid, Thioctic Acid, Lactic Acid, Xanthan Gum, Caprylyl Glycol, Ethylhexylglycerin

2,3-Butanediol

Dicaprylyl Carbonate

Glyceryl Stearate

Cocoglycerides

Ceramide Ag

Ceramide NP

Hydroxyacetophenone

Sodium Hyaluronate

Ceramide EOP

Ceramide Ng

Ceramide AP

Adenosine

Tocopherol

Butyrospermum Parkii Butter

Palmitoyl Tripeptide-5

Hexylene Glycol

Trehalose

Cholesterol

Sodium Phytate

Urea

Hydrogenated Lecithin

Citrullus Lanatus Seed Oil

Sodium PCA

Polyquaternium-51

Triacetin

Sodium Polyacrylate

Ethylhexyl Stearate

Phenoxyethanol

Sodium Stearoyl Glutamate

Water, 2,3-Butanediol, Dicaprylyl Carbonate, Glycerin, Glyceryl Stearate, Cocoglycerides, Ceramide Ag, Ceramide NP, Hydroxyacetophenone, Sodium Hyaluronate, Ceramide EOP, Ceramide Ng, Ceramide AP, Adenosine, Tocopherol, Butyrospermum Parkii Butter, Palmitoyl Tripeptide-5, Hexylene Glycol, Trehalose, Cholesterol, Squalane, Sodium Phytate, Urea, Hydrogenated Lecithin, Citrullus Lanatus Seed Oil, Caprylyl Glycol, Sodium PCA, Polyquaternium-51, Triacetin, Sodium Polyacrylate, Xanthan Gum, Ethylhexyl Stearate, Phenoxyethanol, Sodium Stearoyl Glutamate, Ethylhexylglycerin

Reviews

Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Caprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created.

Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin.

Because it is not a free-fatty acid, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on).

Ethylhexylglycerin is created from glycerin. It is a multitasker ingredient that:

The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.

Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Squalane is the hydrogenated and shelf-stable form of squalene (a lipid that naturally occurs in human sebum).

It is an emollient and skin conditioning agent that is able to integrate seamlessly into the skin's lipid barrier without clogging pores.

This is due to how structurally similar it is to what your skin already produces.

Though it is mostly an emollient that helps soften and hydrate skin, it also has some humectant and occlusive action. Humectants help the skin retain moisture while occlusives seal it in, making squalane a triple-threat moisturizer.

Research shows it has antioxidant capabilities that help protect against stressors like UV exposure, specifically UVA induced oxidative stress. This study also found that it supports collagen biosynthesis in human dermal fibroblasts.

No clinical study has reported significant adverse effects and irritation reactions are very rare from this ingredient (even at 100% concentration).

Overall, it's a fantastic ingredient for hydration and is suitable for all skin types.

This depends on the source. Squalane can be derived from both plants and animals. Most squalane used in skincare comes from plants.

Please note: the source of squalane is only known if disclosed by the brand. We recommend reaching out to the brand if you have any questions about their squalane.

Read more about squalene with an "e".

Though squalane is often called an oil, it’s technically not one. It is a hydrocarbon, meaning it is only made of carbon and hydrogen. True oils are triglycerides and made of fatty acids and glycerol.

The term “oil-free” isn’t regulated so companies can define it however they want. Some exclude all oils, while others just avoid mineral oil or comedogenic oils.

Squalane has a comedogenic rating of 1 from the original 1972 study that tested raw ingredients under occlusion on rabbit ears. This system is not standardized or peer-reviewed, and using the raw ingredients is very different from how diluted cosmetic formulations are used on human skin.

A comedogenic rating of 1 means it is "unlikely to clog pores" according to the original rating system.

The overall formula of a product matters more than the individual ingredients on whether or not it will cause clogged pores.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.

On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.

Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.

Similar Comparisons

The reference edit

Ingredients, questions
& further reading.

Connected source records selected through this article’s public topic index.

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Formula cabinet

Ingredients & structured notes

Ingredient index

Ingredients Explained

  1. 01These ingredients are found in both products.
  2. 02Ingredients higher up in an ingredient list are typically present in a larger amount.
  3. 03This ingredient is a preservative and often used for it's anti-static properties. You'll most likely see this ingredient in hair conditioners.
  4. 04It does not cause irritation or sensitization in leave-on products at 1-5%.
  5. 05Citric Acid is an alpha hydroxy acid (AHA) naturally found in citrus fruits like oranges, lemons, and limes.
  6. 06Like other AHAs, citric acid can exfoliate skin by breaking down the bonds that hold dead skin cells together. This helps reveal smoother and brighter skin underneath.
  7. 07However, this exfoliating effect only happens at high concentrations (20%) which can be hard to find in cosmetic products.
  8. 08Due to this, citric acid is usually included in small amounts as a pH adjuster. This helps keep products slightly more acidic and compatible with skin's natural pH.
  9. 09In skincare formulas, citric acid can:
  10. 10While it can provide some skin benefits, research shows lactic acid and glycolic acid are generally more effective and less irritating exfoliants.
  11. 11Most citric acid used in skincare today is made by fermenting sugars (usually from molasses). This synthetic version is identical to the natural citrus form but easier to stabilize and use in formulations.
  12. 12Rosacea skin has a lower threshold for acids generally, with 62.5% of rosacea subjects in one study reacting to lactic acid in a sting test. This is why we mark citric acid as a potential rosacea trigger.
  13. 13However, this ingredient shows up as a pH adjuster or chelator at roughly 0.1-1% in many products. These low levels are unlikely to be an issue for rosacea skin and becomes a potential trigger at exfoliating concentrations (20%). Because everybody's…
  14. 14Disodium EDTA is a chelating agent. It grabs onto and deactivates metal ions that sneak into your products from water, packaging, or air.
  15. 15This ingredient mainly works behind the scenes and helps with:
  16. 16On top of that, this ingredient can counteract the effects of hard water by binding to the minerals in it.
  17. 17One thing worth knowing is that Disodium EDTA has been shown to be a mild penetration enhancer. It can help other ingredients absorb into skin more effectively which can be a double-edged sword (great for actives, but can also make the active too st…
  18. 18Clinical patch testing showed no significant skin irritation at typical use concentrations and minimal dermal absorption.
  19. 19You'll most likely see this ingredient near the end of an ingredient list. It's typically found in concentrations less than 1%.
  20. 20Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).
Source · skinsort.com
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Product index

Related product references

Product

Paula's Choice Defense Moisturiser

Paula's Choice Defense Moisturiser Paula's Choice Defense Moisturiser ingredients explained: Aqua, Glycerin, Ethylhexyl Palmitate, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copo…

Source: incidecoder.comView reference →
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Comparison edit

Read side by side