Skin science article
COSRX Balancium Comfort Ceramide Cream Versus Coxir Intensive EGF Peptide Mask Pack
COSRX Balancium Comfort Ceramide Cream Versus Coxir Intensive EGF Peptide Mask Pack This barrier-repair moisturizer is formulated around Centella Asiatica Leaf Water and Ceramide NP to strengthen the skin barrier and calm redness. This anti-aging moisturizer i
COSRX Balancium Comfort Ceramide Cream Versus Coxir Intensive EGF Peptide Mask Pack
This barrier-repair moisturizer is formulated around Centella Asiatica Leaf Water and Ceramide NP to strengthen the skin barrier and calm redness.
This anti-aging moisturizer is formulated around Niacinamide and Sh-Oligopeptide-1 to soften the look of wrinkles.
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Centella Asiatica Leaf Water
Butylene Glycol
Glycerin
Helianthus Annuus Seed Oil
Caprylic/Capric Triglyceride
Cetearyl Alcohol
Betaine
1,2-Hexanediol
Cetearyl Olivate
Elaeis Guineensis Oil
Ceramide NP
Sorbitan Olivate
Hydrogenated Lecithin
Triethylhexanoin
Beeswax
Elaeis Guineensis Kernel Oil
Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer
Ethylhexylglycerin
Cyclohexasiloxane
Cassia Obtusifolia Seed Extract
Sucrose Distearate
Dipropylene Glycol
Panthenol
Niacinamide
Dimethicone/Vinyl Dimethicone Crosspolymer
Glyceryl Stearate
Xanthan Gum
Sodium Hyaluronate
Limonene
Citrus Aurantium Bergamia Fruit Oil
Asiaticoside
Asiatic Acid
Madecassic Acid
Linalool
Centella Asiatica Leaf Water, Butylene Glycol, Glycerin, Helianthus Annuus Seed Oil, Caprylic/Capric Triglyceride, Cetearyl Alcohol, Betaine, 1,2-Hexanediol, Cetearyl Olivate, Elaeis Guineensis Oil, Ceramide NP, Sorbitan Olivate, Hydrogenated Lecithin, Triethylhexanoin, Beeswax, Elaeis Guineensis Kernel Oil, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Ethylhexylglycerin, Cyclohexasiloxane, Cassia Obtusifolia Seed Extract, Sucrose Distearate, Dipropylene Glycol, Panthenol, Niacinamide, Dimethicone/Vinyl Dimethicone Crosspolymer, Glyceryl Stearate, Xanthan Gum, Sodium Hyaluronate, Limonene, Citrus Aurantium Bergamia Fruit Oil, Asiaticoside, Asiatic Acid, Madecassic Acid, Linalool
Water
Paraffinum Liquidum
Butylene Glycol Dicaprylate/Dicaprate
Polyglyceryl-3 Methylglucose Distearate
Glyceryl Acrylate/Acrylic Acid Copolymer
Propylene Glycol
Polysorbate 60
Cyclomethicone
Macadamia Integrifolia Seed Oil
Butyrospermum Parkii Butter
Panax Ginseng Root Extract
Acanthopanax Senticosus Root Extract
Punica Granatum Fruit Extract
Carthamus Tinctorius Flower Extract
Panax Ginseng Callus Culture Extract
Hydrolyzed Collagen
Ganoderma Lucidum Extract
Grifola Frondosa Extract
Phellinus Linteus Extract
Fomes Officinalis Extract
Sarcodon Aspratus Extract
Trametes Versicolor Extract
Inonotus Obliquus Extract
Agaricus Blazei Extract
Tricholoma Matsutake Extract
Propolis Extract
Sh-Oligopeptide-1
Copper Tripeptide-1
Dimethicone
Arachidyl Alcohol
Behenyl Alcohol
Arachidyl Glucoside
Polysorbate 20
Stearic Acid
Phenoxyethanol
Arginine
Carbomer
Allantoin
Tocopheryl Acetate
Adenosine
Disodium EDTA
Parfum
Water, Glycerin, Paraffinum Liquidum, Butylene Glycol, Dipropylene Glycol, Caprylic/Capric Triglyceride, Sodium Hyaluronate, Butylene Glycol Dicaprylate/Dicaprate, Polyglyceryl-3 Methylglucose Distearate, Niacinamide, Glyceryl Acrylate/Acrylic Acid Copolymer, Propylene Glycol, 1,2-Hexanediol, Cetearyl Alcohol, Polysorbate 60, Cyclomethicone, Macadamia Integrifolia Seed Oil, Butyrospermum Parkii Butter, Betaine, Panax Ginseng Root Extract, Acanthopanax Senticosus Root Extract, Punica Granatum Fruit Extract, Carthamus Tinctorius Flower Extract, Panax Ginseng Callus Culture Extract, Hydrolyzed Collagen, Ganoderma Lucidum Extract, Grifola Frondosa Extract, Phellinus Linteus Extract, Fomes Officinalis Extract, Sarcodon Aspratus Extract, Trametes Versicolor Extract, Inonotus Obliquus Extract, Agaricus Blazei Extract, Tricholoma Matsutake Extract, Propolis Extract, Hydrogenated Lecithin, Sh-Oligopeptide-1, Copper Tripeptide-1, Dimethicone, Arachidyl Alcohol, Behenyl Alcohol, Arachidyl Glucoside, Polysorbate 20, Stearic Acid, Phenoxyethanol, Arginine, Carbomer, Panthenol, Allantoin, Tocopheryl Acetate, Adenosine, Disodium EDTA, Xanthan Gum, Ethylhexylglycerin, Parfum
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Alternatives
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse.
It is a:
Humectant, drawing moisture into the skin
Emollient, helping to soften skin
Solvent, dispersing and stabilizing formulas
Preservative booster, enhancing the antimicrobial activity of other preservatives
Betaine is a humectant. Like hyaluronic acid, it helps attract and retain moisture in the skin. It’s known for being gentle and for helping the skin maintain balanced hydration.
Betaine is mainly used to improve hydration and support calmer skin. It helps skin cells regulate water balance because it functions as an osmolyte.
Some studies suggest betaine may support making skin tone more even.
Fun fact: Betaine naturally exists in the skin and the body. In cosmetic products, it can be either plant-derived (most commonly from sugar beets) or synthetically produced for consistency and stability.
Betaine is also known as trimethylglycine.
Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:
Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.
Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.
Caprylic/Capric Triglyceride (aka MCT Oil) is a lightweight emollient, solvent, and texture enhancer. It is considered a skin-softener by helping to prevent moisture loss.
Though it behaves like an oil, it is not technically one due to its chemical composition. One perk of this ingredient is that it is very stable, resistant to oxidation, and unlikely to go rancid.
In practice, that translates to a long shelf life and a consistently elegant skin feel.
While there is an assumption Caprylic Triglyceride can clog pores due to it being derived from coconut oil, there is no research supporting this. Just patch test if you have concerns.
Fractionated coconut oil and MCT Oil are both listed as Caprylic/Capric Triglyceride according to INCI. This is because INCI names are based on the ingredient’s final chemical composition and not its marketing name or source.
This ingredient is treated as the gold standard fungal acne safe oil. Even though it is coconut derived, the problematic lauric acid is stripped out.
This leaves just caprylic (C8) and capric (C10) acid. These chain lengths actually trend antifungal; a 2020 study found caprylic acid was enough to disrupt Malassezia furfur cell membrane, with a caprylic acid derivative damaging membrane structures at concentrations as low as 0.2%.
Cetearyl alcohol is a waxy mixture of two fatty alcohols: cetyl alcohol and stearyl alcohol. It is an emollient and emulsifier.
Despite having "alcohol" in its name, it has nothing to do with drying solvent alcohols; the FDA also allows "alcohol-free" products to contain fatty alcohols like this ingredient.
It plays several roles in a formula:
Typical use levels for this ingredient sit around 1-10% and the Cosmetic Ingredient Review Expert Panel has affirmed safety at concentrations up to 25% in leave-on products.
Multiple assessments have found it to be non-irritating and non-sensitizing to most people.
However, there have been some cases of allergic contact dermatitis in patients with chronically compromised skin barriers.
Cetearyl alcohol has a comedogenic rating of 2 and irritancy rating of 1. Both of these numbers come from the 1989 study that used rabbit ears; a "2" means mildly comedogenic and a "1" means low irritancy.
Here's the catch: rabbit skin is more sensitive than human skin and throws a lot of false positives. A 1996 reappraisal found that ingredients rated 1-2 in the rabbit ear tests are generally safe for humans.
Remember comedogenic ratings are unable to assess the entire formula of a product or how it will react on your skin. Just be sure to patch test if you are unsure about certain ingredients.
This ingredient is not fungal acne safe. Cetearyl alcohol is a fatty alcohol with chain lengths that fall within the range that Malassezia can metabolize.
A 2019 study has also observed Malassezia growth in the presence of this ingredient, confirming it to be not-fungal acne safe.
Dipropylene Glycol is a synthetically created humectant, stabilizer, and solvent.
This ingredient helps:
Dipropylene glycol is technically an alcohol, but it belongs to the glycol family (often considered part of the ‘good’ alcohols). This means it is hydrating and gentle on skin unlike drying solvent alcohols like denatured alcohol.
As a masking agent, Dipropylene Glycol can be used to cover the smell of other ingredients. However, it does not have a scent.
Studies show Dipropylene Glycol is considered safe to use in skincare.
Ethylhexylglycerin is created from glycerin. It is a multitasker ingredient that:
The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.
Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.
Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Hydrogenated Lecithin is a more stable version of lecithin.
It's made by taking lecithin (a phospholipid commonly found in soybeans and egg yolks) and hydrogenating it. This just means the unsaturated fatty acids are turned into saturated ones so they don't go bad as easily.
This ingredient is an emollient, emulsifier, and penetration enhancer. As an emollient, it helps soften and hydrate skin by trapping moisture within. As an emulsifier, it prevents oil and water ingredients from separating.
Hydrogenated Lecithin can form tiny spherical structures made of phospholipid bilayers called liposomes. These liposomes are able to capture compounds inside their structure and deliver them through the skin barrier.
Because phospholipids are a natural component of our cell membranes, this ingredient is inherently compatible with skin.
A 2021 study found lecithin-based surfactants were less harsh and more tolerable comared to Sodium Lauryl Sulfate (SLS).
Niacinamide is a multitasking form of vitamin B3 that strengthens the skin barrier, reduces pores and dark spots, regulates oil, and improves signs of aging.
And the best part? It's gentle and well-tolerated by most skin types, including sensitive and reactive skin.
You might have heard of "niacin flush", or the reddening of skin that causes itchiness. Niacinamide has not been found to cause this.
In very rare cases, some individuals may not be able to tolerate niacinamide at all or experience an allergic reaction to it.
If you are experiencing flaking, irritation, and dryness with this ingredient, be sure to double check all your products as this ingredient can be found in all categories of skincare.
When incorporating niacinamide into your routine, look out for concentration amounts. Typically, 5% niacinamide provides benefits such as fading dark spots. However, if you have sensitive skin, it is better to begin with a smaller concentration.
When you apply niacinamide to your skin, your body converts it into nicotinamide adenine dinucleotide (NAD). NAD is an essential coenzyme that is already found in your cells as "fuel" and powers countless biological processes.
In your skin, NAD helps repair cell damage, produce new healthy cells, support collagen production, strengthen the skin barrier, and fight environmental stressors (like UV and pollution).
Our natural NAD levels start to decline with age, leading to slower skin repair, visible aging, and a weaker skin barrier. By providing your skin niacinamide, you're recharging your skin's NAD levels. This leads to stronger, healthier, and younger looking skin.
Another name for vitamin B3 is nicotinamide. This vitamin is water-soluble and our bodies don't store it. We obtain Vitamin B3 from either food or skincare. Meat, fish, wheat, yeast, and leafy greens contain vitamin B3.
The type of niacinamide used in skincare is synthetically created.
Panthenol is a common ingredient that helps hydrate and soothe the skin. It is found naturally in our skin and hair.
There are two forms of panthenol: D and L.
D-panthenol is also known as dexpanthenol. Most cosmetics use dexpanthenol or a mixture of D and L-panthenol.
Panthenol is famous due to its ability to go deeper into the skin's layers. Using this ingredient has numerous pros (and no cons):
Like hyaluronic acid, panthenol is a humectant. Humectants are able to bind and hold large amounts of water to keep skin hydrated.
This ingredient works well for wound healing. It works by increasing tissue in the wound and helps close open wounds.
Once oxidized, panthenol converts to pantothenic acid. Panthothenic acid is found in all living cells.
This ingredient is also referred to as pro-vitamin B5.
Sodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity.
In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface.
Interestingly, the size of the molecule affects its behavior:
Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.
Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.
You'll typically see concentrations between 0.1-2% for this ingredient.
Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.
On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.
Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.