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Skin science article

Coxir Intensive EGF Peptide Mask Pack Versus Laneige Water Sleeping Mask

Coxir Intensive EGF Peptide Mask Pack Versus Laneige Water Sleeping Mask This anti-aging moisturizer is formulated around Niacinamide and Sh-Oligopeptide-1 to soften the look of wrinkles. This hydrating overnight mask is formulated around Ceramide AP and Squal

Coxir Intensive EGF Peptide Mask Pack Versus Laneige Water Sleeping Mask

This anti-aging moisturizer is formulated around Niacinamide and Sh-Oligopeptide-1 to soften the look of wrinkles.

This hydrating overnight mask is formulated around Ceramide AP and Squalane to hydrate skin and strengthen the skin barrier.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Glycerin

Paraffinum Liquidum

Butylene Glycol

Dipropylene Glycol

Caprylic/Capric Triglyceride

Sodium Hyaluronate

Butylene Glycol Dicaprylate/Dicaprate

Polyglyceryl-3 Methylglucose Distearate

Niacinamide

Glyceryl Acrylate/Acrylic Acid Copolymer

Propylene Glycol

1,2-Hexanediol

Cetearyl Alcohol

Polysorbate 60

Cyclomethicone

Macadamia Integrifolia Seed Oil

Butyrospermum Parkii Butter

Betaine

Panax Ginseng Root Extract

Acanthopanax Senticosus Root Extract

Punica Granatum Fruit Extract

Carthamus Tinctorius Flower Extract

Panax Ginseng Callus Culture Extract

Hydrolyzed Collagen

Ganoderma Lucidum Extract

Grifola Frondosa Extract

Phellinus Linteus Extract

Fomes Officinalis Extract

Sarcodon Aspratus Extract

Trametes Versicolor Extract

Inonotus Obliquus Extract

Agaricus Blazei Extract

Tricholoma Matsutake Extract

Propolis Extract

Hydrogenated Lecithin

Sh-Oligopeptide-1

Copper Tripeptide-1

Dimethicone

Arachidyl Alcohol

Behenyl Alcohol

Arachidyl Glucoside

Polysorbate 20

Stearic Acid

Phenoxyethanol

Arginine

Carbomer

Panthenol

Allantoin

Tocopheryl Acetate

Adenosine

Disodium EDTA

Xanthan Gum

Ethylhexylglycerin

Parfum

Water, Glycerin, Paraffinum Liquidum, Butylene Glycol, Dipropylene Glycol, Caprylic/Capric Triglyceride, Sodium Hyaluronate, Butylene Glycol Dicaprylate/Dicaprate, Polyglyceryl-3 Methylglucose Distearate, Niacinamide, Glyceryl Acrylate/Acrylic Acid Copolymer, Propylene Glycol, 1,2-Hexanediol, Cetearyl Alcohol, Polysorbate 60, Cyclomethicone, Macadamia Integrifolia Seed Oil, Butyrospermum Parkii Butter, Betaine, Panax Ginseng Root Extract, Acanthopanax Senticosus Root Extract, Punica Granatum Fruit Extract, Carthamus Tinctorius Flower Extract, Panax Ginseng Callus Culture Extract, Hydrolyzed Collagen, Ganoderma Lucidum Extract, Grifola Frondosa Extract, Phellinus Linteus Extract, Fomes Officinalis Extract, Sarcodon Aspratus Extract, Trametes Versicolor Extract, Inonotus Obliquus Extract, Agaricus Blazei Extract, Tricholoma Matsutake Extract, Propolis Extract, Hydrogenated Lecithin, Sh-Oligopeptide-1, Copper Tripeptide-1, Dimethicone, Arachidyl Alcohol, Behenyl Alcohol, Arachidyl Glucoside, Polysorbate 20, Stearic Acid, Phenoxyethanol, Arginine, Carbomer, Panthenol, Allantoin, Tocopheryl Acetate, Adenosine, Disodium EDTA, Xanthan Gum, Ethylhexylglycerin, Parfum

Methyl Trimethicone

Ceramide AP

Squalane

Phenyl Trimethicone

PCA Dimethicone

Caprylyl Methicone

Ammonium Acryloyldimethyltaurate/Vp Copolymer

Lactobacillus Ferment Lysate

Propanediol

Tromethamine

Acrylates/C10-30 Alkyl Acrylate Crosspolymer

Glyceryl Caprylate

Raffinose

Stearyl Behenate

Malachite Extract

Inulin Lauryl Carbamate

Tryptophan

Hydroxypropyl Bispalmitamide Mea

Beta-Glucan

Limonene

Saururus Chinensis Extract

Acorus Gramineus Extract

Linalool

Tocopherol

Water, Butylene Glycol, Glycerin, Methyl Trimethicone, Ceramide AP, 1,2-Hexanediol, Squalane, Phenyl Trimethicone, PCA Dimethicone, Caprylyl Methicone, Ammonium Acryloyldimethyltaurate/Vp Copolymer, Lactobacillus Ferment Lysate, Carbomer, Propanediol, Tromethamine, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Glyceryl Caprylate, Ethylhexylglycerin, Disodium EDTA, Raffinose, Stearyl Behenate, Malachite Extract, Parfum, Polyglyceryl-3 Methylglucose Distearate, Inulin Lauryl Carbamate, Niacinamide, Tryptophan, Hydroxypropyl Bispalmitamide Mea, Beta-Glucan, Limonene, Saururus Chinensis Extract, Acorus Gramineus Extract, Linalool, Tocopherol

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Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse.

It is a:

Humectant, drawing moisture into the skin

Emollient, helping to soften skin

Solvent, dispersing and stabilizing formulas

Preservative booster, enhancing the antimicrobial activity of other preservatives

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.

Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.

Carbomer is a synthetic thickening and gelling agent. It's basically the ingredient that gives a lot of serums, gels, creams, and sunscreens their smooth, non-sticky texture.

Although legally permitted at very high levels, carbomers are normally used at concentrations below 1%.

It also needs to be neutralized to actually thicken, and because it is a large molecule, it doesn't really penetrate the skin barrier.

Allergy-wise, the risk is very low. Clinical studies show carbomers have low potential for skin irritation/sensitization even at concentrations up to 100%.

A 2024 UK study patch-tested 1,302 patients and found true allergy to the parent group of carbomer to be rare with no confirmed relevant reactions.

Disodium EDTA is a chelating agent. It grabs onto and deactivates metal ions that sneak into your products from water, packaging, or air.

This ingredient mainly works behind the scenes and helps with:

On top of that, this ingredient can counteract the effects of hard water by binding to the minerals in it.

One thing worth knowing is that Disodium EDTA has been shown to be a mild penetration enhancer. It can help other ingredients absorb into skin more effectively which can be a double-edged sword (great for actives, but can also make the active too strong if you have sensitive skin).

Clinical patch testing showed no significant skin irritation at typical use concentrations and minimal dermal absorption.

You'll most likely see this ingredient near the end of an ingredient list. It's typically found in concentrations less than 1%.

Ethylhexylglycerin is created from glycerin. It is a multitasker ingredient that:

The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.

Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Niacinamide is a multitasking form of vitamin B3 that strengthens the skin barrier, reduces pores and dark spots, regulates oil, and improves signs of aging.

And the best part? It's gentle and well-tolerated by most skin types, including sensitive and reactive skin.

You might have heard of "niacin flush", or the reddening of skin that causes itchiness. Niacinamide has not been found to cause this.

In very rare cases, some individuals may not be able to tolerate niacinamide at all or experience an allergic reaction to it.

If you are experiencing flaking, irritation, and dryness with this ingredient, be sure to double check all your products as this ingredient can be found in all categories of skincare.

When incorporating niacinamide into your routine, look out for concentration amounts. Typically, 5% niacinamide provides benefits such as fading dark spots. However, if you have sensitive skin, it is better to begin with a smaller concentration.

When you apply niacinamide to your skin, your body converts it into nicotinamide adenine dinucleotide (NAD). NAD is an essential coenzyme that is already found in your cells as "fuel" and powers countless biological processes.

In your skin, NAD helps repair cell damage, produce new healthy cells, support collagen production, strengthen the skin barrier, and fight environmental stressors (like UV and pollution).

Our natural NAD levels start to decline with age, leading to slower skin repair, visible aging, and a weaker skin barrier. By providing your skin niacinamide, you're recharging your skin's NAD levels. This leads to stronger, healthier, and younger looking skin.

Another name for vitamin B3 is nicotinamide. This vitamin is water-soluble and our bodies don't store it. We obtain Vitamin B3 from either food or skincare. Meat, fish, wheat, yeast, and leafy greens contain vitamin B3.

The type of niacinamide used in skincare is synthetically created.

Parfum is a catch-all term for an ingredient or more that is used to give a scent to products.

Also called "fragrance", this ingredient can be a blend of hundreds of chemicals or plant oils. This means every product with "fragrance" or "parfum" in the ingredients list is a different mixture.

For instance, Habanolide is a proprietary trade name for a specific aroma chemical. When used as a fragrance ingredient in cosmetics, most aroma chemicals fall under the broad labeling category of “FRAGRANCE” or “PARFUM” according to EU and US regulations.

The term 'parfum' or 'fragrance' is not regulated in many countries. In many cases, it is up to the brand to define this term.

For instance, many brands choose to label themselves as "fragrance-free" because they are not using synthetic fragrances. However, their products may still contain ingredients such as essential oils that are considered a fragrance by INCI standards.

One example is Calendula flower extract. Calendula is an essential oil that still imparts a scent or 'fragrance'.

Depending on the blend, the ingredients in the mixture can cause allergies and sensitivities on the skin. Some ingredients that are known EU allergens include linalool and citronellol.

Parfum can also be used to mask or cover an unpleasant scent.

The bottom line is: not all fragrances/parfum/ingredients are created equally. If you are worried about fragrances, we recommend taking a closer look at an ingredient. And of course, we always recommend speaking with a professional.

Polyglyceryl-3 Methylglucose Distearate is a plant-derived emulsifier whose only job is to keep the oily and watery parts of a formula blended so it doesn't separate into layers.

It's compatible with a wide-range of active ingredients and especially good at making emulsions survive heat/freeze cycles.

Typical use concentrations range from 2-3% and it works across a pH of 4.5-8.5.

This ingredient has been found safe to use in cosmetics and has a low irritation profile.

Because it's build on stearic acid, it may not be fungal acne safe. Stearic acid is a C18 fatty acid that falls within the range (C11-24) that Malassezia can feed on.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

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