Peptide Skincare & BeautySkin science and ingredient guides

Skin science article

COSRX The 6 Peptide Skin Booster Serum Versus Pyunkang Yul Calming Moisture Mist

COSRX The 6 Peptide Skin Booster Serum Versus Pyunkang Yul Calming Moisture Mist This anti-aging serum is formulated around Niacinamide and Acetyl Hexapeptide-8 to soften the look of wrinkles and strengthen the skin barrier. This calming toner is formulated ar

COSRX The 6 Peptide Skin Booster Serum Versus Pyunkang Yul Calming Moisture Mist

This anti-aging serum is formulated around Niacinamide and Acetyl Hexapeptide-8 to soften the look of wrinkles and strengthen the skin barrier.

This calming toner is formulated around Panthenol and Allantoin to calm redness and hydrate skin.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Dipropylene Glycol

Glycerin

Pentylene Glycol

1,2-Hexanediol

Niacinamide

Acetyl Hexapeptide-8

Copper Tripeptide-1

Sh-Polypeptide-121

Dipeptide Diaminobutyroyl Benzylamide Diacetate

Oligopeptide-68

Palmitoyl Tripeptide-8

Allantoin

Sodium Hyaluronate

Acetyl Glucosamine

Serine

Alanine

Glycine

Threonine

Arginine

Proline

Betaine

Sodium PCA

Sodium Lactate

PCA

Glutamic Acid

Lysine Hcl

Tocopherol

Dextran

Glycine Soja Oil

Hydrogenated Lecithin

Ammonium Acryloyldimethyltaurate/Vp Copolymer

Polyacrylate Crosspolymer-6

Butylene Glycol

Xanthan Gum

Ethylhexylglycerin

Adenosine

Polyquaternium-51

Disodium EDTA

Citric Acid

Caprylyl Glycol

T-Butyl Alcohol

Potassium Sorbate

Sodium Oleate

Water, Dipropylene Glycol, Glycerin, Pentylene Glycol, 1,2-Hexanediol, Niacinamide, Acetyl Hexapeptide-8, Copper Tripeptide-1, Sh-Polypeptide-121, Dipeptide Diaminobutyroyl Benzylamide Diacetate, Oligopeptide-68, Palmitoyl Tripeptide-8, Allantoin, Sodium Hyaluronate, Acetyl Glucosamine, Serine, Alanine, Glycine, Threonine, Arginine, Proline, Betaine, Sodium PCA, Sodium Lactate, PCA, Glutamic Acid, Lysine Hcl, Tocopherol, Dextran, Glycine Soja Oil, Hydrogenated Lecithin, Ammonium Acryloyldimethyltaurate/Vp Copolymer, Polyacrylate Crosspolymer-6, Butylene Glycol, Xanthan Gum, Ethylhexylglycerin, Adenosine, Polyquaternium-51, Disodium EDTA, Citric Acid, Caprylyl Glycol, T-Butyl Alcohol, Potassium Sorbate, Sodium Oleate

Propanediol

Trehalose

Hydroxyacetophenone

Panthenol

C12-14 Pareth-12

Sodium Citrate

Gluconolactone

Centella Asiatica Extract

Hamamelis Virginiana Extract

Melaleuca Alternifolia Leaf Extract

Salix Alba Bark Extract

Polyglyceryl-10 Myristate

Bambusa Vulgaris Extract

Caprylic/Capric Triglyceride

Ethylhexyl Palmitate

Cetyl Ethylhexanoate

Lonicera Japonica Flower Extract

Hydrolyzed Hyaluronic Acid

Hydroxypropyltrimonium Hyaluronate

Sodium Hyaluronate Crosspolymer

Sodium Acetylated Hyaluronate

Water, Propanediol, Dipropylene Glycol, Trehalose, Butylene Glycol, Caprylyl Glycol, Hydroxyacetophenone, Pentylene Glycol, Panthenol, C12-14 Pareth-12, Sodium Citrate, Ethylhexylglycerin, Citric Acid, Disodium EDTA, Allantoin, Gluconolactone, Centella Asiatica Extract, Hamamelis Virginiana Extract, Melaleuca Alternifolia Leaf Extract, Salix Alba Bark Extract, Polyglyceryl-10 Myristate, 1,2-Hexanediol, Bambusa Vulgaris Extract, Caprylic/Capric Triglyceride, Ethylhexyl Palmitate, Cetyl Ethylhexanoate, Lonicera Japonica Flower Extract, Sodium Hyaluronate, Hydrolyzed Hyaluronic Acid, Hydroxypropyltrimonium Hyaluronate, Sodium Hyaluronate Crosspolymer, Sodium Acetylated Hyaluronate

Reviews

Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse.

It is a:

Humectant, drawing moisture into the skin

Emollient, helping to soften skin

Solvent, dispersing and stabilizing formulas

Preservative booster, enhancing the antimicrobial activity of other preservatives

Allantoin is a soothing ingredient known for its protective and moisturizing properties; it's basically a quiet workhorse ingredient you can find in a huge range of cosmetics.

Though it can be derived from the comfrey plant, allantoin is produced synthetically for cosmetic products to ensure purity.

Research shows it can encourage your skin cells to turn over and renew by stimulating keratinocyte and fibroblast proliferation.

It also has mild keratolytic properties to help loosen and shed dead skin cells without being harsh.

Studies also suggest allantoin can help calm inflammation by dialing down some of the chemical signals your skin sends out when it is irritated.

This ingredient is typically used in the 0.1-0.5% range, and the FDA recognizes it as a skin protectant in OTC products up to 2%.

Overall, allantoin is a wonderful addition to most routines; it is stable across a wide pH range (~4-8), works well with other ingredients, and is considered non-sensitizing/non-irritating.

Fun fact: Allantoin is naturally occurring in comfrey root, beets, chamomile, and wheat sprouts. Our bodies even produce it as a byproduct of uric acid metabolism.

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.

Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.

Caprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created.

Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin.

Because it is not a free-fatty acid, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on).

Citric Acid is an alpha hydroxy acid (AHA) naturally found in citrus fruits like oranges, lemons, and limes.

Like other AHAs, citric acid can exfoliate skin by breaking down the bonds that hold dead skin cells together. This helps reveal smoother and brighter skin underneath.

However, this exfoliating effect only happens at high concentrations (20%) which can be hard to find in cosmetic products.

Due to this, citric acid is usually included in small amounts as a pH adjuster. This helps keep products slightly more acidic and compatible with skin's natural pH.

In skincare formulas, citric acid can:

While it can provide some skin benefits, research shows lactic acid and glycolic acid are generally more effective and less irritating exfoliants.

Most citric acid used in skincare today is made by fermenting sugars (usually from molasses). This synthetic version is identical to the natural citrus form but easier to stabilize and use in formulations.

Rosacea skin has a lower threshold for acids generally, with 62.5% of rosacea subjects in one study reacting to lactic acid in a sting test. This is why we mark citric acid as a potential rosacea trigger.

However, this ingredient shows up as a pH adjuster or chelator at roughly 0.1-1% in many products. These low levels are unlikely to be an issue for rosacea skin and becomes a potential trigger at exfoliating concentrations (20%). Because everybody's skin is unique, we recommend a patch test if you are unsure.

Dipropylene Glycol is a synthetically created humectant, stabilizer, and solvent.

This ingredient helps:

Dipropylene glycol is technically an alcohol, but it belongs to the glycol family (often considered part of the ‘good’ alcohols). This means it is hydrating and gentle on skin unlike drying solvent alcohols like denatured alcohol.

As a masking agent, Dipropylene Glycol can be used to cover the smell of other ingredients. However, it does not have a scent.

Studies show Dipropylene Glycol is considered safe to use in skincare.

Disodium EDTA is a chelating agent. It grabs onto and deactivates metal ions that sneak into your products from water, packaging, or air.

This ingredient mainly works behind the scenes and helps with:

On top of that, this ingredient can counteract the effects of hard water by binding to the minerals in it.

One thing worth knowing is that Disodium EDTA has been shown to be a mild penetration enhancer. It can help other ingredients absorb into skin more effectively which can be a double-edged sword (great for actives, but can also make the active too strong if you have sensitive skin).

Clinical patch testing showed no significant skin irritation at typical use concentrations and minimal dermal absorption.

You'll most likely see this ingredient near the end of an ingredient list. It's typically found in concentrations less than 1%.

Ethylhexylglycerin is created from glycerin. It is a multitasker ingredient that:

The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.

Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.

Pentylene Glycol (1,2-pentanediol) is a multitasking little diol with three main roles in a formula:

Research on alkanediols (the family pentylene glycol belongs to) show they work by disrupting microbial cell membranes. This disruption helps the primary preservative system in a product work more effectively at lower doses.

On the safety side, the Cosmetic Ingredient Review Expert Panel has concluded this ingredient to be safe as used in current cosmetic practices + concentrations.

Typical use levels in a formula run about 1-5%.

Sodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity.

In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface.

Interestingly, the size of the molecule affects its behavior:

Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.

Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.

You'll typically see concentrations between 0.1-2% for this ingredient.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

Similar Comparisons

The reference edit

Ingredients, questions
& further reading.

Connected source records selected through this article’s public topic index.

01

Formula cabinet

Ingredients & structured notes

Ingredient index

Ingredients Explained

  1. 01These ingredients are found in both products.
  2. 02Ingredients higher up in an ingredient list are typically present in a larger amount.
  3. 031,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse.
  4. 04It is a:
  5. 05Humectant, drawing moisture into the skin
  6. 06Emollient, helping to soften skin
  7. 07Solvent, dispersing and stabilizing formulas
  8. 08Preservative booster, enhancing the antimicrobial activity of other preservatives
  9. 09Alanine is an amino acid and is already found in the human body. Our skin uses alanine to build collagen, elastin, and keratin.
  10. 10Allantoin is a soothing ingredient known for its protective and moisturizing properties; it's basically a quiet workhorse ingredient you can find in a huge range of cosmetics.
  11. 11Though it can be derived from the comfrey plant, allantoin is produced synthetically for cosmetic products to ensure purity.
  12. 12Research shows it can encourage your skin cells to turn over and renew by stimulating keratinocyte and fibroblast proliferation.
  13. 13It also has mild keratolytic properties to help loosen and shed dead skin cells without being harsh.
  14. 14Studies also suggest allantoin can help calm inflammation by dialing down some of the chemical signals your skin sends out when it is irritated.
  15. 15This ingredient is typically used in the 0.1-0.5% range, and the FDA recognizes it as a skin protectant in OTC products up to 2%.
  16. 16Overall, allantoin is a wonderful addition to most routines; it is stable across a wide pH range (~4-8), works well with other ingredients, and is considered non-sensitizing/non-irritating.
  17. 17Fun fact: Allantoin is naturally occurring in comfrey root, beets, chamomile, and wheat sprouts. Our bodies even produce it as a byproduct of uric acid metabolism.
  18. 18Arginine is a semi-essential amino acid. This just means our bodies can product a bit on its own, but sometimes needs a little boost from food sources.
  19. 19It is a part of your skin's natural moisturizing factor (NMF), or the water-loving molecules in your outermost layer of skin (stratum corneum) that keeps everything hydrated and happy.
  20. 20Here's an interesting thing about Arginine: your skin converts it into urea through the Krebs-Henseleit urea cycle. Urea is one of the most effective humectants your skin naturally produces.
Source · skinsort.com
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Product index

Related product references

Product

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Source: incidecoder.comView reference →
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Comparison edit

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