Skin science article
Estée Lauder Revitalizing Supreme + Night Versus Estée Lauder Resilience Multi-Effect Tri-Peptide Face And Neck Creme SPF 15
Estée Lauder Revitalizing Supreme + Night Versus Estée Lauder Resilience Multi-Effect Tri-Peptide Face And Neck Creme SPF 15 This anti-aging night moisturizer is formulated around Niacinamide and Moringa Oleifera Seed Extract to soften the look of wrinkles and
Estée Lauder Revitalizing Supreme + Night Versus Estée Lauder Resilience Multi-Effect Tri-Peptide Face And Neck Creme SPF 15
This anti-aging night moisturizer is formulated around Niacinamide and Moringa Oleifera Seed Extract to soften the look of wrinkles and hydrate skin.
This anti-aging day moisturizer is formulated around Acetyl Hexapeptide-8 to soften the look of wrinkles.
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Glycine Soja Oil
Caprylic/Capric/Myristic/Stearic Triglyceride
Glycerin
Prunus Amygdalus Dulcis Oil
Dimethicone
Stearyl Alcohol
Butylene Glycol
Steareth-2
Cocos Nucifera Oil
Vitis Vinifera Seed Oil
Glyceryl Stearate
Niacinamide
Propanediol
Steareth-21
Moringa Oleifera Seed Extract
Limonium Vulgare Flower/Leaf/Stem Extract
Sodium Hyaluronate
Acetyl Hexapeptide-8
Laminaria Digitata Extract
Whey Protein
Acetyl Glucosamine
Opuntia Tuna Fruit Extract
Tocopheryl Acetate
Citrullus Lanatus Fruit Extract
Persea Gratissima Oil
Mangifera Indica Seed Oil
Aminopropyl Ascorbyl Phosphate
Algae Extract
Caffeine
Cucumis Sativus Fruit Extract
Pyrus Malus Fruit Extract
Narcissus Tazetta Bulb Extract
Sigesbeckia Orientalis Extract
Butyrospermum Parkii Butter
Lens Esculenta Fruit Extract
Silybum Marianum Seed Oil
Limnanthes Alba Seed Oil
Hordeum Vulgare Extract
Simmondsia Chinensis Seed Oil
Macadamia Integrifolia Seed Oil
Olea Europaea Fruit Oil
Dextrin Palmitate
Sodium Hydroxide
Carbomer
Behenyl Alcohol
Caprylyl Glycol
Hydroxyethyl Urea
Propylene Glycol Dicaprate
Cholesterol
Isoceteth-20
Lactoperoxidase
Helianthus Annuus Seedcake
Sodium Polyaspartate
Sorbitol
Glucose
Cetyl Alcohol
Myristyl Alcohol
Sodium Lactate
Citric Acid
Sodium PCA
Glucose Oxidase
Potassium Phosphate
Sodium Chloride
Parfum
Disodium EDTA
BHT
Potassium Sorbate
Sodium Benzoate
Phenoxyethanol
CI 19140
CI 14700
CI 77491
CI 77492
Water, Glycine Soja Oil, Caprylic/Capric/Myristic/Stearic Triglyceride, Glycerin, Prunus Amygdalus Dulcis Oil, Dimethicone, Stearyl Alcohol, Butylene Glycol, Steareth-2, Cocos Nucifera Oil, Vitis Vinifera Seed Oil, Glyceryl Stearate, Niacinamide, Propanediol, Steareth-21, Moringa Oleifera Seed Extract, Limonium Vulgare Flower/Leaf/Stem Extract, Sodium Hyaluronate, Acetyl Hexapeptide-8, Laminaria Digitata Extract, Whey Protein, Acetyl Glucosamine, Opuntia Tuna Fruit Extract, Tocopheryl Acetate, Citrullus Lanatus Fruit Extract, Persea Gratissima Oil, Mangifera Indica Seed Oil, Aminopropyl Ascorbyl Phosphate, Algae Extract, Caffeine, Cucumis Sativus Fruit Extract, Pyrus Malus Fruit Extract, Narcissus Tazetta Bulb Extract, Sigesbeckia Orientalis Extract, Butyrospermum Parkii Butter, Lens Esculenta Fruit Extract, Silybum Marianum Seed Oil, Limnanthes Alba Seed Oil, Hordeum Vulgare Extract, Simmondsia Chinensis Seed Oil, Macadamia Integrifolia Seed Oil, Olea Europaea Fruit Oil, Dextrin Palmitate, Sodium Hydroxide, Carbomer, Behenyl Alcohol, Caprylyl Glycol, Hydroxyethyl Urea, Propylene Glycol Dicaprate, Cholesterol, Isoceteth-20, Lactoperoxidase, Helianthus Annuus Seedcake, Sodium Polyaspartate, Sorbitol, Glucose, Cetyl Alcohol, Myristyl Alcohol, Sodium Lactate, Citric Acid, Sodium PCA, Glucose Oxidase, Potassium Phosphate, Sodium Chloride, Parfum, Disodium EDTA, BHT, Potassium Sorbate, Sodium Benzoate, Phenoxyethanol, CI 19140, CI 14700, CI 77491, CI 77492
Neopentyl Glycol Diheptanoate
Ethylhexyl Salicylate
Butyl Methoxydibenzoylmethane
Octocrylene
Butyloctyl Salicylate
Pentaerythrityl Tetraethylhexanoate
Polyethylene
Di-C12-15 Alkyl Fumarate
Petrolatum
Hydrogenated Lecithin
Hydrogenated Polyisobutene
Octyldodecyl Myristate
Hexyldecyl Stearate
Cucumis Melo Fruit Extract
Polygonum Aviculare Extract
Myrtus Communis Leaf Extract
Tetradecyl Aminobutyroylvalylaminobutyric Urea Trifluoroacetate
Propylene Glycol Dicaprylate
Artemia Extract
C12-16 Alcohols
Trehalose
Ethylhexylglycerin
PEG-100 Stearate
Palmitic Acid
Glycine Soja Sterols
Isohexadecane
Polymethyl Methacrylate
Trifluoroacetyl Tripeptide-2
Zinc PCA
Polysilicone-11
Polysorbate 80
Faex Extract
Potato Starch Modified
Decarboxy Carnosine Hcl
Xanthan Gum
Potassium Sulfate
Acrylamide/Sodium Acryloyldimethyltaurate Copolymer
Dextran
Hexylene Glycol
Mica
CI 77891
Water, Neopentyl Glycol Diheptanoate, Ethylhexyl Salicylate, Butyl Methoxydibenzoylmethane, Octocrylene, Cetyl Alcohol, Glycerin, Butyloctyl Salicylate, Pentaerythrityl Tetraethylhexanoate, Polyethylene, Di-C12-15 Alkyl Fumarate, Petrolatum, Hydrogenated Lecithin, Butylene Glycol, Propanediol, Hydrogenated Polyisobutene, Octyldodecyl Myristate, Hexyldecyl Stearate, Behenyl Alcohol, Cucumis Melo Fruit Extract, Polygonum Aviculare Extract, Myrtus Communis Leaf Extract, Laminaria Digitata Extract, Acetyl Hexapeptide-8, Tetradecyl Aminobutyroylvalylaminobutyric Urea Trifluoroacetate, Lactoperoxidase, Glucose Oxidase, Cholesterol, Propylene Glycol Dicaprylate, Aminopropyl Ascorbyl Phosphate, Sodium Hyaluronate, Glucose, Algae Extract, Artemia Extract, Acetyl Glucosamine, Sigesbeckia Orientalis Extract, Glyceryl Stearate, Persea Gratissima Oil, Dimethicone, C12-16 Alcohols, Trehalose, Ethylhexylglycerin, PEG-100 Stearate, Caffeine, Palmitic Acid, Glycine Soja Sterols, Caprylyl Glycol, Isohexadecane, Polymethyl Methacrylate, Trifluoroacetyl Tripeptide-2, Tocopheryl Acetate, Zinc PCA, Polysilicone-11, Polysorbate 80, Faex Extract, Potato Starch Modified, Decarboxy Carnosine Hcl, Xanthan Gum, Parfum, Sodium Hydroxide, Potassium Sulfate, Acrylamide/Sodium Acryloyldimethyltaurate Copolymer, Dextran, Hexylene Glycol, Disodium EDTA, BHT, Potassium Sorbate, Phenoxyethanol, CI 14700, Mica, CI 77891
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Alternatives
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Acetyl Glucosamine is an antioxidant and humectant. It is an amino acid sugar and is naturally found in our skin.
The cool thing about this ingredient? It helps the skin produce hyaluronic acid and boost hydration. It also has antioxidant benefits to protect skin cells.
When paired with niacinamide, Acetyl Glucosamine has been shown to be effective at reducing discoloration.
Acetyl Hexapeptide-8 (also known as Argireline) is a synthetic hexapeptide that is often called a "topical Botox alternative".
It works by mimicking how Botox relaxes muscles; it interferes with the signaling process that tells your facial muscles to contract. This can help soften expression lines like forehead wrinkles or crow's feet over time.
The comparison to Botox does have limits because the molecule is water-loving and relatively large.
Acetyl Hexapeptide-8 has a hard time absorbing deeply enough through the skin's outer barrier to actually reach the muscles.
So whether it truly works the way Botox does at a biological level is still up for debate, but early clinical outcomes are fairly encouraging.
A 12 week human study of a multi-ingredient regimen containing this ingredient saw:
While some studies have observed improvements in wrinkle appearance, it is important to note that more consistent results are seen in multi-ingredient formulations (vs just Acetyl Hexapeptide-8 alone).
Some research studies also used higher concentrations (up to 10%) while this ingredient is usually found in concentrations up to 0.005% in leave-on formulations.
Algae Extract is a confusing name. This is because algae is an informal term for a group of 30,000 aquatic organisms that can photosynthesize.
The term 'algae extract' can refer to any one, or a blend of, the 30,000 types.
Algae is rich in antioxidants. Antioxidants help fight free-radicals. Free-radicals are molecules that may damage your skin cells, such as pollution.
Algae can also help with soothing and hydrating skin.
Many different types of algae have different benefits.
Aminopropyl Ascorbyl Phosphate (AAP) is a form of Vitamin C. AAP was made as a more stable alternative to Ascorbic Acid by combining Ascorbic Acid (pure Vitamin C) with 3-aminoproply dehydrogen phosphate.
As a type of Vitamin C, it has antioxidant properties. Antioxidants help fight free-radical molecules, or molecules that may damage your skin cells.
AAP has been shown to help reduce signs of hyperigmentation and age-spots.
AAP is water soluble.
Vitamin C can help to reduce redness, improve skin texture, reduce the effects of aging, and reduce the visibility of dark spots.
Read more about other types of Vitamin C:
Behenyl Alcohol is a type of fatty alcohol (these are different from the drying, solvent alcohols).
Fatty Alcohols have hydrating properties and are most often used as an emollient or to thicken a product. They are usually derived from natural fats and oils; behenyl alcohol is derived from the fats of vegetable oils.
Emollients help keep your skin soft and hydrated by creating a film that traps moisture in.
In 2000, Behenyl Alcohol was approved by the US as medicine to reduce the duration of cold sores.
BHT is a synthetic antioxidant and preservative.
As an antioxidant, it helps your body fight off free-radicals. Free-radicals are molecules that may damage your skin cells.
As a preservative, it is used to stabilize products and prevent them from degrading. Specifically, BHT prevents degradation from oxidation.
The concerns related to BHT come from oral studies; this ingredient is currently allowed for use by both the FDA and EU.
However, it was recently restricted for use in the UK as of April 2024.
Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:
Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.
Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.
Caffeine is a naturally occurring plant compound found in coffee beans, tea leaves, cocoa pods, and guarana.
As an antioxidant, caffeine protects your skin from free radical damage caused by UV exposure and envionrmnetal stressors.
Early research also shows that caffeine can help calm redness, soothe irritated skin, and support hair growth by stimulating microcirculation in the scalp.
You might have seen eye creams marketing caffeine as a depuffing ingredient. This is because it is a vasoconstrictor meaning it can temporarily constrict blood vessels, though clinical evidence for this specific use is still limited.
Most skincare products contain this ingredient at concentrations between 1-6%. It is able to penetrate skin easily regardless of skin type or thickness.
Just so you know, a very small number of case reports describe caffeine-induced allergy. This ingredient is generally well-tolerated, non-irritating, and non-sensitizing for the majority of people.
Caprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created.
Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin.
Because it is not a free-fatty acid, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on).
Cetyl Alcohol is a fatty alcohol. Fatty Alcohols are most often used as an emollient or to thicken a product.
Its main roles are:
Though it has "alcohol" in the name, it is not related to denatured alcohol or ethyl alcohol.
The FDA allows products labeled "alcohol-free" to have fatty alcohols.
This ingredient may not be fungal acne safe. It is a primary fatty alcohol with a chain length above 12 carbons. A study from 2019 show Malassezia can feed on fatty alcohols in this range, so it may trigger fungal acne in those prone to it.
Cholesterol is a lipid that is naturally found in human skin and is one of the three key components of your skin barrier. In skincare, it is an emollient and barrier-repairing ingredient.
It works by fitting directly into the lipid layers of skin to help restore structure and reduce transepidermal water loss (TEWL).
This is a great ingredient for dry, compromised, or aging skin; our skin starts to produce less cholesterol with age.
Research shows cholesterol works best in combination with ceramides and fatty acids, the other two major components in your skin barrier.
Cholesterol is also a well-establish penetration enhancer and can help other actives absorb more effectively.
Cosmetic-grade cholesterol is usually derived from lanolin but plant and synthetic options also exist. We recommend reaching out to the brand if you have questions about their source of cholesterol.
Ci 14700, also known as Red No. 4, is a synthetic red dye derived from petroleum. It is water soluble.
Dimethicone is a type of synthetic silicone created from natural materials such as quartz. It is also known as polydimethylsiloxane.
What it does:
Dimethicone comes in different viscosities:
Depending on the viscosity, dimethicone has different properties.
Ingredients lists don't always show which type is used, so we recommend reaching out to the brand if you have questions about the viscosity.
This ingredient is unlikely to cause irritation because it does not get absorbed into skin. However, people with silicone allergies should be careful about using this ingredient.
Note: Dimethicone may contribute to pilling. This is because it is not oil or water soluble, so pilling may occur when layered with products. When mixed with heavy oils in a formula, the outcome is also quite greasy.
Disodium EDTA is a chelating agent. It grabs onto and deactivates metal ions that sneak into your products from water, packaging, or air.
This ingredient mainly works behind the scenes and helps with:
On top of that, this ingredient can counteract the effects of hard water by binding to the minerals in it.
One thing worth knowing is that Disodium EDTA has been shown to be a mild penetration enhancer. It can help other ingredients absorb into skin more effectively which can be a double-edged sword (great for actives, but can also make the active too strong if you have sensitive skin).
Clinical patch testing showed no significant skin irritation at typical use concentrations and minimal dermal absorption.
You'll most likely see this ingredient near the end of an ingredient list. It's typically found in concentrations less than 1%.
Glucose is a simple sugar (a monosaccharide). In skincare, it is mostly a humectant and skin conditioning agent.
Mechanistically, it has multiple hydroxyl groups that hydrogen-bond to water. This pulls moisture into the upper layers of skin to keep the surface soft and hydrated.
It's worth knowing sugars are already a natural component of the skin's NMF (natural moisturizing factor) so it's a molecule that your stratum corneum is well-acquainted with.
Just so you know, glucose is hydrophilic (water-loving) and the stratum corneum is a strong barrier to hydrophilic compounds. This just means penetration is slow and most of the action is happening on the surface.
Gram-to-gram, glucose is not as efficient as a humectant as glycerin. This is why you'll likely see glycose paired with stronger humectants for a bigger hydration payoff.
In skincare, glucose is typically derived from corn or other starch sources.
We don't have a description for Glucose Oxidase yet.
Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Glyceryl Stearate is made by reacting glycerin with stearic acid (typically sourced from plant oils like palm or coconut). It's an emulsifier, emollient, and mild occlusive.
Emulsifiers help ingredients like oil and water stay mixed so your formula stays nicely blended and uniform in texture.
This ingredient is typically used in concentrations between 1-10%. Studies have found it to be non-sensitizing, non-phototoxic, and non-photoallergenic.
A close cousin of this ingredient is Glyceryl Stearate SE ("self-emulsifying"). This just has a small amount of sodium or potassium stearate added so it can emulsify without a co-emulsifier.
Since this ingredient is an ester of a C18 fatty acid, it may not be fungal acne safe. The Malassezia yeast can potentially metabolize within the C11-C24 range.
Fun fact: The human body also creates Glyceryl Stearate naturally.
We don't have a description for Lactoperoxidase yet.
Laminaria Digitata Extract comes from the big brown seaweed (or kelp) that grows in the North Atlantic. In skincare, it's mostly used as a skin protectant and conditioning agent.
The most interesting stuff inside is mostly just sugars and minerals: fucoidan (a sulfated polysaccharide), laminarin (a beta-glucan), alginates, and phlorotannins (seaweed polyphenols).
Any antioxidant and soothing claims mostly come from those polysaccharides; crude laminarin and fucoidan from Laminaria digitata do show antioxidant and anti-inflammatory activity in lab assays.
Just know that the lab assays are test-tube work on isolated compounds and not clinical trials on the finished extract.
Realistically, this ingredient is a nice-feeling and hydrating skin conditioner (not really an active).
Safety-wise, it's one of the better documented seaweeds and safe to be used in cosmetics according to the CIR Expert Panel.
Industry surveys find that usage concentrations run can be found up to 5% in bubble baths and leave-on usage is more likely 0.1-3%.
The risk of allergy is also quite low as human repeat insult patch tests (under 5% and blends containing 8-12%) came back non-irritating and non-sensitizing. Rabbit studies came back negative too, though one trade mixture at 1.5-2.5% in water + propylene glycol did cause moderate irritation at 30 minutes.
Reported seaweed allergies in the literature are almost all occupational (people handling wet kelp) or from a totally unrelated blue/green alga.
At this time, there's actually no published comedogenicity test on it and the evidence that does exist points away from clogging.
Laminaria Digitata Extract has never been run through the rabbit ear assay or the Mills & Kligman human model and it isn't in Fulton's 1989 list of tested comedogenic ratings.
The CIR's brown algae review pulled every published and unpublished study industry had on 82 seaweed ingredients and found no comedogenicity data for any of them.
So any number you see online was assigned by a person and not actually measured.
In 2012, Capitanio et al. ran an 8-week double-blind, vehicle-controlled trial in 60 people with mild acne using a Laminaria digitata-derived oligosaccharide complexed with 0.1% zinc pyrrolidone.
They found comedones, papules and pustules dropped significantly more in the active group than the vehicle group at 2, 4 and 8 weeks.
Caveats for this study: a Laminaria digitata-derived oligosaccharide is just fraction and not the plain extract, and the zinc is likely doing real work. Still, the study found comedones went down in acne-prone skin.
This fits mechanistically. Comedogenesis is largely a lipid story and this is water-soluble polysaccharides, minerals, and polyphenols. There's nothing really to plug a follicle with.
The real caveat is the carrier: some supplier versions come dispersed in caprylic/capric triglycerides.
The 0-5 scale comes from applying ingredients to the inside of an albino rabbit's ear. Rabbit follicles are far more reactive than human ones so it over-predicts. Even petrolatum was reassigned as non-comedogenic by the original scientist, Kligman.
Here are three more problems of comedogenic ratings:
Parfum is a catch-all term for an ingredient or more that is used to give a scent to products.
Also called "fragrance", this ingredient can be a blend of hundreds of chemicals or plant oils. This means every product with "fragrance" or "parfum" in the ingredients list is a different mixture.
For instance, Habanolide is a proprietary trade name for a specific aroma chemical. When used as a fragrance ingredient in cosmetics, most aroma chemicals fall under the broad labeling category of “FRAGRANCE” or “PARFUM” according to EU and US regulations.
The term 'parfum' or 'fragrance' is not regulated in many countries. In many cases, it is up to the brand to define this term.
For instance, many brands choose to label themselves as "fragrance-free" because they are not using synthetic fragrances. However, their products may still contain ingredients such as essential oils that are considered a fragrance by INCI standards.
One example is Calendula flower extract. Calendula is an essential oil that still imparts a scent or 'fragrance'.
Depending on the blend, the ingredients in the mixture can cause allergies and sensitivities on the skin. Some ingredients that are known EU allergens include linalool and citronellol.
Parfum can also be used to mask or cover an unpleasant scent.
The bottom line is: not all fragrances/parfum/ingredients are created equally. If you are worried about fragrances, we recommend taking a closer look at an ingredient. And of course, we always recommend speaking with a professional.
This ingredient is also known as Avocado oil. It's the cold-pressed oil from the flesh of the avocado fruit packed with fatty acids (mostly oleic acid).
The rich fatty acid profile allows it to function as a skin conditioning agent and emollient; it helps soften and smooth skin while reducing water loss.
Preclinical research has found that topical avocado oil increased collagen synthesis and reduced inflammation during wound healing, giving it some skin-repairing credibility.
The unsaponifiable fraction of the oil is also interesting: studies on avocado unsaponifiables showed that it helped skin produce more collagen and other structural compounds that support healing.
The CIR Expert Panel has found this ingredient to be non-irritating in formulations.
It's a great ingredient for dry or compromised skin. Just know it may not be fungal acne safe. This is because the oleic acid content falls within the range that Malassezia can use as a food source.
Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).
It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.
On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.
Another perk of this ingredient is that it stays functional across a wide pH range (3-10).
You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.
Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.
Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.
Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.
Potassium Sorbate is a preservative used to prevent yeast and mold in products. It is commonly found in both cosmetic and food products.
This ingredient comes from potassium salt derived from sorbic acid. Sorbic acid is a natural antibiotic and effective against fungus.
Both potassium sorbate and sorbic acid can be found in baked goods, cheeses, dried meats, dried fruit, ice cream, pickles, wine, yogurt, and more.
You'll often find this ingredient used with other preservatives.
Propanediol is an all-star ingredient. It softens, hydrates, and smooths the skin.
It’s often used to:
Propanediol is not likely to cause sensitivity and considered safe to use. It is derived from corn or petroleum with a clear color and no scent.
We don't have a description for Sigesbeckia Orientalis Extract yet.
Sodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity.
In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface.
Interestingly, the size of the molecule affects its behavior:
Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.
Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.
You'll typically see concentrations between 0.1-2% for this ingredient.
Sodium Hydroxide is also known as lye or caustic soda. It is used to adjust the pH of products; many ingredients require a specific pH to be effective.
In small amounts, sodium hydroxide is considered safe to use. However, large amounts may cause chemical burns due to its high alkaline.
Your skin has a natural pH and acid mantle. This acid mantle helps prevent harmful bacteria from breaking through. The acid mantle also helps keep your skin hydrated.
"Alkaline" refers to a high pH level. A low pH level would be considered acidic.
Tocopheryl Acetate is a stable, shelf-friendly form of vitamin E.
Formulators love it because plain vitamin E oxidizes quickly once it hits air. This acetate version stays stable and resists going off, helping to extend a product's shelf life.
It's actually inactive on its own and works like a slow-release "storage" form; the enzymes in your skin called esterases gradually convert it into active vitamin E over time.
One in vivo study showed 5% of the acetate in the living layer of the epidermis converted to vitamin E after 5 days of application. This study also found the skin gained protection against UV damage even though the conversion was slow and small.
Once converted, vitamin E acts as a skin's main fat-soluble antioxidant that fights free radicals to protect skin from damage.
Topical vitamin E generally boosts the skin's photoprotection, and it reduced UV-damage in animal models.
This ingredient has some brightening potential but it's more of a prevention ingredient than spot-fader. Cell studies show it can slow down melanin production but it's worth noting that it's not the most powerful brightener out there.
Overall, it has a pretty solid safety profile and has been found to be non-irritating and non-comedogenic. Allergic reactions may happen but stay rare due to how widely the ingredient gets used.
The concentration will vary depending on the formula; industry data shows 0.1% in baby lotions, 3% in lipsticks, and 5% in foot powders. You can also find this ingredient at 100% in a pure vitamin E oil.
Most leave-on skincare keeps it at the lower end, often between 0.5-1%.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!