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Hanasui Power Bright Expert Serum Versus SkinMedica TNS® Advanced+ Serum

Hanasui Power Bright Expert Serum Versus SkinMedica TNS® Advanced+ Serum This brightening serum is formulated around Niacinamide and Glycyrrhiza Glabra Root Extract to brighten dull-looking skin and fade the look of dark spots. What's inside Key Ingredients Be

Hanasui Power Bright Expert Serum Versus SkinMedica TNS® Advanced+ Serum

This brightening serum is formulated around Niacinamide and Glycyrrhiza Glabra Root Extract to brighten dull-looking skin and fade the look of dark spots.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Niacinamide

Glycerin

Hydroxyethyl Urea

Betaine

Methyl Gluceth-20

Ethoxydiglycol

Propanediol

Phenoxyethanol

Cyclopentasiloxane

Biosaccharide Gum-1

Butylene Glycol

Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer

Polyacrylate Crosspolymer-6

Ethylhexyl Cocoate

Allantoin

Pisum Sativum Extract

Dimethiconol

Ethylhexylglycerin

Disodium EDTA

Tocopheryl Acetate

Sodium Hyaluronate

Chenopodium Quinoa Seed Extract

Glycyrrhiza Glabra Root Extract

Dimethylmethoxy Chromanyl Palmitate

Water, Niacinamide, Glycerin, Hydroxyethyl Urea, Betaine, Methyl Gluceth-20, Ethoxydiglycol, Propanediol, Phenoxyethanol, Cyclopentasiloxane, Biosaccharide Gum-1, Butylene Glycol, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Polyacrylate Crosspolymer-6, Ethylhexyl Cocoate, Allantoin, Pisum Sativum Extract, Dimethiconol, Ethylhexylglycerin, Disodium EDTA, Tocopheryl Acetate, Sodium Hyaluronate, Chenopodium Quinoa Seed Extract, Glycyrrhiza Glabra Root Extract, Dimethylmethoxy Chromanyl Palmitate

Pentylene Glycol

Human Neonatal Fibroblast Conditioned Media

Glycereth-7 Triacetate

Shea Butter Ethyl Esters

Lactococcus Ferment Lysate

Whey Protein

Chlorella Vulgaris Extract

Saccharide Isomerate

Dimer Tripeptide-43

Vitis Vinifera Flower Cell Extract

Pyrus Malus Fruit Extract

Hydroxyacetophenone

Xanthan Gum

Polyacrylate-13

Polyisobutene

Sclerotium Gum

PEG-12 Dimethicone

Lecithin

Pullulan

Sodium Citrate

Polysorbate 20

Aminomethyl Propanol

Water, Pentylene Glycol, Human Neonatal Fibroblast Conditioned Media, Glycereth-7 Triacetate, Shea Butter Ethyl Esters, Glycerin, Ethoxydiglycol, Lactococcus Ferment Lysate, Whey Protein, Chlorella Vulgaris Extract, Saccharide Isomerate, Dimer Tripeptide-43, Vitis Vinifera Flower Cell Extract, Pyrus Malus Fruit Extract, Hydroxyacetophenone, Tocopheryl Acetate, Propanediol, Xanthan Gum, Polyacrylate Crosspolymer-6, Polyacrylate-13, Polyisobutene, Sclerotium Gum, PEG-12 Dimethicone, Lecithin, Pullulan, Butylene Glycol, Sodium Citrate, Polysorbate 20, Aminomethyl Propanol, Disodium EDTA, Phenoxyethanol, Ethylhexylglycerin

Reviews

Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.

Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.

Disodium EDTA is a chelating agent. It grabs onto and deactivates metal ions that sneak into your products from water, packaging, or air.

This ingredient mainly works behind the scenes and helps with:

On top of that, this ingredient can counteract the effects of hard water by binding to the minerals in it.

One thing worth knowing is that Disodium EDTA has been shown to be a mild penetration enhancer. It can help other ingredients absorb into skin more effectively which can be a double-edged sword (great for actives, but can also make the active too strong if you have sensitive skin).

Clinical patch testing showed no significant skin irritation at typical use concentrations and minimal dermal absorption.

You'll most likely see this ingredient near the end of an ingredient list. It's typically found in concentrations less than 1%.

Ethoxydiglycol (aka Diethylene Glycol Monoethyl Ether) is one of the cosmetic world's quiet problem solvers.

In a formula, it is a solvent that dissolves tricky ingredients that don't want to mix in and helps spread ingredients evenly across your skin without leaving a greasy or sticky feeling

This makes it great for hard-to-dissolve actives like vitamin C, benzoyl peroxide, and self-tanner DHA.

It also has mild humectant and penetration enhancer abilities so it can help some actives absorb a little deeper.

The penetration boost is backed by lab research: studies using human skin samples found it improved how well an active dissolves into the upper layer of skin rather than tearing down your skin barrier. Reviews of its mechanism also describe it interacting gently with the lipids and water in your outermost layer of skin.

Just know this penetration-enhancing effect is not universal. It helps a lot in some formulas and did very little in others (so the benefit really depends on the specific product).

Safety-wise, the evidence is reassuring. The Cosmetic Ingredient Review Expert Panel reviewed it and concluded it's safe for use in cosmetics and recognized it as non-irritating, non-sensitizing, and non-comedogenic in skincare.

Typical leave-on skincare usage lands around 1-10%. The EU has sets caps of 2.6% in non-spray products, 10% in rinse-offs, 7% in oxidative hair dye, and 5% in non-oxidative hair dye.

Ethylhexylglycerin is created from glycerin. It is a multitasker ingredient that:

The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.

Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).

It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.

On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.

Another perk of this ingredient is that it stays functional across a wide pH range (3-10).

You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.

Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.

Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.

Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.

Polyacrylate Crosspolymer-6 is a texture enhancer and pH adjuster.

It is be used to thicken water-based products and create a gel-texture with a velvet feel.

One manufacturer claims this ingredient to have a pH range of 2-8 and to be biodegradable.

This ingredient is also known as Sepimax Zen.

Propanediol is an all-star ingredient. It softens, hydrates, and smooths the skin.

It’s often used to:

Propanediol is not likely to cause sensitivity and considered safe to use. It is derived from corn or petroleum with a clear color and no scent.

Tocopheryl Acetate is a stable, shelf-friendly form of vitamin E.

Formulators love it because plain vitamin E oxidizes quickly once it hits air. This acetate version stays stable and resists going off, helping to extend a product's shelf life.

It's actually inactive on its own and works like a slow-release "storage" form; the enzymes in your skin called esterases gradually convert it into active vitamin E over time.

One in vivo study showed 5% of the acetate in the living layer of the epidermis converted to vitamin E after 5 days of application. This study also found the skin gained protection against UV damage even though the conversion was slow and small.

Once converted, vitamin E acts as a skin's main fat-soluble antioxidant that fights free radicals to protect skin from damage.

Topical vitamin E generally boosts the skin's photoprotection, and it reduced UV-damage in animal models.

This ingredient has some brightening potential but it's more of a prevention ingredient than spot-fader. Cell studies show it can slow down melanin production but it's worth noting that it's not the most powerful brightener out there.

Overall, it has a pretty solid safety profile and has been found to be non-irritating and non-comedogenic. Allergic reactions may happen but stay rare due to how widely the ingredient gets used.

The concentration will vary depending on the formula; industry data shows 0.1% in baby lotions, 3% in lipsticks, and 5% in foot powders. You can also find this ingredient at 100% in a pure vitamin E oil.

Most leave-on skincare keeps it at the lower end, often between 0.5-1%.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

Similar Comparisons

The reference edit

Ingredients, questions
& further reading.

Connected source records selected through this article’s public topic index.

01

Formula cabinet

Ingredients & structured notes

Ingredient index

Ingredients Side-by-side

  1. 01Water
  2. 02Pentylene Glycol
  3. 03Human Neonatal Fibroblast Conditioned Media
  4. 04Glycereth-7 Triacetate
  5. 05Shea Butter Ethyl Esters
  6. 06Glycerin
  7. 07Ethoxydiglycol
  8. 08Lactococcus Ferment Lysate
  9. 09Whey Protein
  10. 10Chlorella Vulgaris Extract
  11. 11Saccharide Isomerate
  12. 12Dimer Tripeptide-43
  13. 13Vitis Vinifera Flower Cell Extract
  14. 14Pyrus Malus Fruit Extract
  15. 15Hydroxyacetophenone
  16. 16Tocopheryl Acetate
  17. 17Propanediol
  18. 18Xanthan Gum
  19. 19Polyacrylate Crosspolymer-6
  20. 20Polyacrylate-13
Source · skinsort.com
02

Product index

Related product references

Product

SkinMedica Tns Advanced+ Serum

SkinMedica Tns Advanced+ Serum SkinMedica Tns Advanced+ Serum ingredients explained: Water/Aqua/Eau, Pentylene Glycol, Human Fibroblast Conditioned Media, Glycereth-7 Triacetate, Shea Butte…

Source: incidecoder.comView reference →

Product

SkinMedica Tns Advanced+ Serum

SkinMedica Tns Advanced+ Serum SkinMedica Tns Advanced+ Serum ingredients explained: Aqua/Water/Eau, Pentylene Glycol, Human Fibroblast Conditioned Media, Glycereth-7 Triacetate, Shea Butte…

Source: incidecoder.comView reference →
03

Comparison edit

Read side by side