Skin science article
IMAGE skincare Vital C Hydrating Anti-Aging Serum Versus Paula's Choice Resist Super Antioxidant Serum
IMAGE skincare Vital C Hydrating Anti-Aging Serum Versus Paula's Choice Resist Super Antioxidant Serum This hydrating serum is formulated around Aloe Barbadensis Leaf Juice and Magnesium Ascorbyl Phosphate to hydrate skin. This anti-aging serum is formulated a
IMAGE skincare Vital C Hydrating Anti-Aging Serum Versus Paula's Choice Resist Super Antioxidant Serum
This hydrating serum is formulated around Aloe Barbadensis Leaf Juice and Magnesium Ascorbyl Phosphate to hydrate skin.
This anti-aging serum is formulated around Tetrahexyldecyl Ascorbate and Palmitoyl Tripeptide-5 to soften the look of wrinkles and brighten dull-looking skin.
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Aloe Barbadensis Leaf Juice
Water
Glycerin
Citrus Aurantium Dulcis Oil
Caprylic/Capric Triglyceride
Limonene
C12-15 Alkyl Benzoate
Cetearyl Olivate
Sorbitan Olivate
Imperata Cylindrica Root Extract
Magnesium Ascorbyl Phosphate
PPG-12/Smdi Copolymer
Tetrahexyldecyl Ascorbate
Glyceryl Stearate
PEG-100 Stearate
Cetyl Alcohol
Dimethicone
Di-PPG-2 Myreth-10 Adipate
Stearic Acid
Phenoxyethanol
Ethylhexyl Methoxycinnamate
Panthenol
Prunus Amygdalus Dulcis Oil
Xanthan Gum
Caprylyl Glycol
Butylene Glycol
Tocopheryl Acetate
Glycine Soja Sterols
Linoleic Acid
Phospholipids
Simmondsia Chinensis Seed Oil
Squalene
Propylene Glycol
Ethylhexylglycerin
Glucosamine Hcl
Hexylene Glycol
Linoleamidopropyl Pg-Dimonium Chloride Phosphate
PEG-8
Pisum Sativum Extract
Citrus Nobilis Peel Oil
Dipotassium Glycyrrhizate
Phyllanthus Emblica Fruit Extract
Stearyl Glycyrrhetinate
Bambusa Vulgaris Leaf/Stem Extract
Tocopherol
Magnesium Aluminum Silicate
Olea Europaea Leaf Extract
Disodium EDTA
Eugenia Caryophyllus Leaf Oil
Yeast Polysaccharides
Sodium Hyaluronate
Glyceryl Polymethacrylate
Carbomer
Eugenol
Ascorbyl Palmitate
Citric Acid
Benzoic Acid
Camellia Sinensis Leaf Extract
Ascorbic Acid
Sodium Lactate
Polysorbate 20
Acrylates/C10-30 Alkyl Acrylate Crosspolymer
Spiraea Ulmaria Flower Extract
Taurine
Corallina Officinalis Extract
Vitis Vinifera Seed Extract
Centella Asiatica Flower/Leaf/Stem Extract
Centella Asiatica Extract
Potassium Sorbate
BHT
Acetyl Hexapeptide-8
Darutoside
Palmitoyl Pentapeptide-4
Arginine
Leucine
Lysine
Sodium Benzoate
Valine
Palmitoyl Tripeptide-1
Aloe Barbadensis Leaf Juice, Water, Glycerin, Citrus Aurantium Dulcis Oil, Caprylic/Capric Triglyceride, Limonene, C12-15 Alkyl Benzoate, Cetearyl Olivate, Sorbitan Olivate, Imperata Cylindrica Root Extract, Magnesium Ascorbyl Phosphate, PPG-12/Smdi Copolymer, Tetrahexyldecyl Ascorbate, Glyceryl Stearate, PEG-100 Stearate, Cetyl Alcohol, Dimethicone, Di-PPG-2 Myreth-10 Adipate, Stearic Acid, Phenoxyethanol, Ethylhexyl Methoxycinnamate, Panthenol, Prunus Amygdalus Dulcis Oil, Xanthan Gum, Caprylyl Glycol, Butylene Glycol, Tocopheryl Acetate, Glycine Soja Sterols, Linoleic Acid, Phospholipids, Simmondsia Chinensis Seed Oil, Squalene, Propylene Glycol, Ethylhexylglycerin, Glucosamine Hcl, Hexylene Glycol, Linoleamidopropyl Pg-Dimonium Chloride Phosphate, PEG-8, Pisum Sativum Extract, Citrus Nobilis Peel Oil, Dipotassium Glycyrrhizate, Phyllanthus Emblica Fruit Extract, Stearyl Glycyrrhetinate, Bambusa Vulgaris Leaf/Stem Extract, Tocopherol, Magnesium Aluminum Silicate, Olea Europaea Leaf Extract, Disodium EDTA, Eugenia Caryophyllus Leaf Oil, Yeast Polysaccharides, Sodium Hyaluronate, Glyceryl Polymethacrylate, Carbomer, Eugenol, Ascorbyl Palmitate, Citric Acid, Benzoic Acid, Camellia Sinensis Leaf Extract, Ascorbic Acid, Sodium Lactate, Polysorbate 20, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Spiraea Ulmaria Flower Extract, Taurine, Corallina Officinalis Extract, Vitis Vinifera Seed Extract, Centella Asiatica Flower/Leaf/Stem Extract, Centella Asiatica Extract, Potassium Sorbate, BHT, Acetyl Hexapeptide-8, Darutoside, Palmitoyl Pentapeptide-4, Arginine, Leucine, Lysine, Sodium Benzoate, Valine, Palmitoyl Tripeptide-1
Cyclopentasiloxane
Palmitoyl Tripeptide-5
Ceramide NP
Tocotrienols
Ubiquinone
Thioctic Acid
Ferulic Acid
Beta-Glucan
Superoxide Dismutase
Epigallocatechin Gallate
Ergothioneine
Glutathione
Xanthophylls
Glycine Soja Seed Extract
Arctostaphylos Uva Ursi Leaf Extract
Lupinus Albus Seed Extract
Curcuma Longa Root
Elaeis Guineensis Oil
Cyclopentasiloxane, Dimethicone, Tetrahexyldecyl Ascorbate, Palmitoyl Tripeptide-5, Ceramide NP, Tocotrienols, Tocopherol, Ubiquinone, Thioctic Acid, Tocopheryl Acetate, Magnesium Ascorbyl Phosphate, Ferulic Acid, Beta-Glucan, Superoxide Dismutase, Epigallocatechin Gallate, Ergothioneine, Glutathione, Xanthophylls, Glycine Soja Seed Extract, Glycerin, Arctostaphylos Uva Ursi Leaf Extract, Lupinus Albus Seed Extract, Curcuma Longa Root, Elaeis Guineensis Oil, Phenoxyethanol
Reviews
Be the first to review
Alternatives
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Dimethicone is a type of synthetic silicone created from natural materials such as quartz. It is also known as polydimethylsiloxane.
What it does:
Dimethicone comes in different viscosities:
Depending on the viscosity, dimethicone has different properties.
Ingredients lists don't always show which type is used, so we recommend reaching out to the brand if you have questions about the viscosity.
This ingredient is unlikely to cause irritation because it does not get absorbed into skin. However, people with silicone allergies should be careful about using this ingredient.
Note: Dimethicone may contribute to pilling. This is because it is not oil or water soluble, so pilling may occur when layered with products. When mixed with heavy oils in a formula, the outcome is also quite greasy.
Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Magnesium Ascorbyl Phosphate (MAP) is a water-soluble form of Vitamin C. It is used in skincare because it tends to be more formulation friendly than pure vitamin C (ascorbic acid).
According to research, MAP has three major benefits:
While MAP is gentler on the skin than ascorbic acid, it is thought to be less easily absorbed into the skin.
In a well-known absorption study, pure vitamin C increased skin vitamin C levels when formulated correctly, but derivatives like MAP did not in that experiment. This suggests MAP may not always convert into active vitamin C in the skin.
Due to MAP's stability up to a pH level of 7, it is more stable to air and sunlight exposure than ascorbic acid. The best pH range for MAP is between 5 and 6.
Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).
It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.
On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.
Another perk of this ingredient is that it stays functional across a wide pH range (3-10).
You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.
Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.
Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.
Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.
Tetrahexyldecyl Ascorbate (THD) is a stable and oil-soluble form of Vitamin C.
THD is special in that it has the ability to travel deeper into skin than traditional ascorbic acid while maintaining the same skin benefits (double win!).
Because it’s oil-soluble, THD dives deep into your skin’s fatty layers (think ceramides and cholesterol) to fight off the kind of free radicals that mess with your skin barrier. This makes it a great pair with water-based vitamin C (ascorbic acid) that mainly works on the surface.
Even at just 0.1%, THD is already showing great antioxidant activity. When used up to 2%, it helps keep your skin happy and calm, especially when it’s stressed from pollution or sun.
Want to fade dark spots or tackle hyperpigmentation? You’ll want 5% or more. Pairing it with brightening buddies like niacinamide or licorice root gives even better results. One study even used 30% THD with other brighteners and saw real results on stubborn discoloration, even in melasma-prone skin.
A note on THD: It’s has a slightly silky, oily texture and usually shows up colorless or pale yellow (though the exact shade can vary by supplier).
While you can sneak it into water-based formulas, it really shines when paired with silicones or oils, which help your skin soak it up better.
THD is pretty stable, but it’s still vulnerable to degradation like ascorbic acid. Too much light or heat (above 113°F / 45°C) can break it down over time. Go for dark and opaque packaging that keeps it safe and shady!
Read more about other types of Vitamin C:
Tocopherol is a fat-soluble antioxidant known as Vitamin E.
You'll find this ingredient in the vast majority of skincare (for good reason). It works to neutralize free radicals, or unstable molecules generated by UV exposure, pollution, and other environmental stressors, before they can cause oxidative damage to your skin cells.
Topically applied tocopherol has been shown to protect against UV damage by ramping up the skin's own natural defense enzymes.
It also acts as a skin conditioning agent; some studies show that regular topical use can improve the skin's water-binding capacity over 2-4 weeks.
This ingredient is especially loved for being a team player. When combined with Vitamin C, the photoprotective effect of both ingredients roughly doubles and the combo also helps reduce UV-induced DNA damage.
This ingredient has some brightening potential but it's more of a prevention ingredient than spot-fader. Cell studies show it can slow down melanin production but it's worth noting that it's not the most powerful brightener out there.
In formulations, it also serves as a stabilizer that helps protect other oxidation-prone ingredients from degrading.
Concentrations usually range from 0.1-1% in most leave-on products.
Tocopheryl Acetate is a stable, shelf-friendly form of vitamin E.
Formulators love it because plain vitamin E oxidizes quickly once it hits air. This acetate version stays stable and resists going off, helping to extend a product's shelf life.
It's actually inactive on its own and works like a slow-release "storage" form; the enzymes in your skin called esterases gradually convert it into active vitamin E over time.
One in vivo study showed 5% of the acetate in the living layer of the epidermis converted to vitamin E after 5 days of application. This study also found the skin gained protection against UV damage even though the conversion was slow and small.
Once converted, vitamin E acts as a skin's main fat-soluble antioxidant that fights free radicals to protect skin from damage.
Topical vitamin E generally boosts the skin's photoprotection, and it reduced UV-damage in animal models.
Overall, it has a pretty solid safety profile and has been found to be non-irritating and non-comedogenic. Allergic reactions may happen but stay rare due to how widely the ingredient gets used.
The concentration will vary depending on the formula; industry data shows 0.1% in baby lotions, 3% in lipsticks, and 5% in foot powders. You can also find this ingredient at 100% in a pure vitamin E oil.
Most leave-on skincare keeps it at the lower end, often between 0.5-1%.