Peptide Skincare & BeautySkin science and ingredient guides

Skin science article

L'adria Eye Patches Versus MEDI-PEEL Hyaluron Dark Benone Peptide 9 Ampoule Eye Patch

L'adria Eye Patches Versus MEDI-PEEL Hyaluron Dark Benone Peptide 9 Ampoule Eye Patch This calming eye mask is formulated around Caffeine and Avena Sativa Kernel Extract to calm redness and hydrate skin. This anti-aging eye mask is formulated around Sodium Hya

L'adria Eye Patches Versus MEDI-PEEL Hyaluron Dark Benone Peptide 9 Ampoule Eye Patch

This calming eye mask is formulated around Caffeine and Avena Sativa Kernel Extract to calm redness and hydrate skin.

This anti-aging eye mask is formulated around Sodium Hyaluronate and Acetyl Hexapeptide-8 to soften the look of wrinkles and hydrate skin.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Sorbitol

Glycerin

Chondrus Crispus Powder

Potassium Chloride

Glucomannan

Allantoin

Caffeine

Avena Sativa Kernel Extract

Dipotassium Glycyrrhizate

Niacinamide

Trehalose

Sodium Hyaluronate

Hydroxyacetophenone

Hydroxyethylcellulose

1,2-Hexanediol

Xanthan Gum

Cellulose Gum

Pentylene Glycol

Butylene Glycol

CI 42090

Water, Sorbitol, Glycerin, Chondrus Crispus Powder, Potassium Chloride, Glucomannan, Allantoin, Caffeine, Avena Sativa Kernel Extract, Dipotassium Glycyrrhizate, Niacinamide, Trehalose, Sodium Hyaluronate, Hydroxyacetophenone, Hydroxyethylcellulose, 1,2-Hexanediol, Xanthan Gum, Cellulose Gum, Pentylene Glycol, Butylene Glycol, CI 42090

Carrageenan

Hydrolyzed Collagen

Hydrolyzed Hyaluronic Acid

Sodium Acetylated Hyaluronate

Hydroxypropyltrimonium Hyaluronate

Potassium Hyaluronate

Sodium Hyaluronate Crosspolymer

Hyaluronic Acid

Pearl Extract

Polysorbate 80

Tocopheryl Acetate

Ubiquinone

Acetyl Hexapeptide-8

Copper Tripeptide-1

Oligopeptide-29

Oligopeptide-32

Palmitoyl Pentapeptide-4

Palmitoyl Tripeptide-1

Palmitoyl Tetrapeptide-7

Glyceryl Polymethacrylate

Propylene Glycol

Palmitoyl Oligopeptide

Palmitoyl Tripeptide-5

Propanediol

Cocos Nucifera Fruit Extract

Pinus Sylvestris Leaf Extract

Ricinus Communis Seed Oil

Butyrospermum Parkii Butter

Betaine

Ceratonia Siliqua Gum

Sucrose

Cyamopsis Tetragonoloba Gum

Calcium Chloride

Calcium Lactate

Caprylic/Capric Triglyceride

Sorbitan Caprylate

PEG-60 Hydrogenated Castor Oil

Diamond Powder

Titanium Dioxide

Oleth-10

Triethoxycaprylylsilane

Polysorbate 60

Simethicone

Methyl Methacrylate Crosspolymer

Aluminum Hydroxide

Synthetic Fluorphlogopite

Arginine

Disodium EDTA

Chlorphenesin

Ethyl Hexanediol

Ethylhexylglycerin

Parfum

Water, Glycerin, Carrageenan, Butylene Glycol, Hydrolyzed Collagen, Sodium Hyaluronate, Hydrolyzed Hyaluronic Acid, Sodium Acetylated Hyaluronate, Hydroxypropyltrimonium Hyaluronate, Potassium Hyaluronate, Sodium Hyaluronate Crosspolymer, Hyaluronic Acid, Pearl Extract, Polysorbate 80, Tocopheryl Acetate, Ubiquinone, Acetyl Hexapeptide-8, Copper Tripeptide-1, Oligopeptide-29, Oligopeptide-32, Palmitoyl Pentapeptide-4, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Glyceryl Polymethacrylate, Propylene Glycol, Palmitoyl Oligopeptide, Palmitoyl Tripeptide-5, Propanediol, Pentylene Glycol, Cocos Nucifera Fruit Extract, Pinus Sylvestris Leaf Extract, Ricinus Communis Seed Oil, Butyrospermum Parkii Butter, Betaine, Allantoin, Dipotassium Glycyrrhizate, Ceratonia Siliqua Gum, Sucrose, Cyamopsis Tetragonoloba Gum, Cellulose Gum, Potassium Chloride, Calcium Chloride, Calcium Lactate, Caprylic/Capric Triglyceride, Sorbitan Caprylate, PEG-60 Hydrogenated Castor Oil, Diamond Powder, Titanium Dioxide, Oleth-10, Triethoxycaprylylsilane, Polysorbate 60, Simethicone, Methyl Methacrylate Crosspolymer, Aluminum Hydroxide, Synthetic Fluorphlogopite, Arginine, Disodium EDTA, Chlorphenesin, Ethyl Hexanediol, 1,2-Hexanediol, Ethylhexylglycerin, Parfum

Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse.

It is a:

Humectant, drawing moisture into the skin

Emollient, helping to soften skin

Solvent, dispersing and stabilizing formulas

Preservative booster, enhancing the antimicrobial activity of other preservatives

Allantoin is a soothing ingredient known for its protective and moisturizing properties; it's basically a quiet workhorse ingredient you can find in a huge range of cosmetics.

Though it can be derived from the comfrey plant, allantoin is produced synthetically for cosmetic products to ensure purity.

Research shows it can encourage your skin cells to turn over and renew by stimulating keratinocyte and fibroblast proliferation.

It also has mild keratolytic properties to help loosen and shed dead skin cells without being harsh.

Studies also suggest allantoin can help calm inflammation by dialing down some of the chemical signals your skin sends out when it is irritated.

This ingredient is typically used in the 0.1-0.5% range, and the FDA recognizes it as a skin protectant in OTC products up to 2%.

Overall, allantoin is a wonderful addition to most routines; it is stable across a wide pH range (~4-8), works well with other ingredients, and is considered non-sensitizing/non-irritating.

Fun fact: Allantoin is naturally occurring in comfrey root, beets, chamomile, and wheat sprouts. Our bodies even produce it as a byproduct of uric acid metabolism.

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.

Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.

Cellulose Gum is a water-soluble polymer that comes from cellulose. It is used to change the texture of a product and to help stabilize emulsions.

As an emulsifier, cellulose gum specifically thicken the texture of water-based products.

This ingredient is considered hypoallergenic and non-toxic. Cellulose Gum can be found in cosmetics, food, and other household goods such as paper products.

Dipotassium Glycyrrhizate comes from licorice root.

Extracts of licorice have demonstrated to have antibacterial, anti‐inflammatory, antiviral, antioxidant properties.

One component, glabridin, has extra potent antioxidant and soothing properties. It has also been found to block pigmentation from UVB rays in guinea pigs.

Licorice Root also contains a flavonoid. Flavonoids are a natural substance from in plants. Flavonoids also have antioxidant properties.

Another component, glycyrrhizin, has been found to have anti-inflammatory and antimicrobial benefits. This may make licorice root extract effective at treating acne. However, more research is needed to support this.

Liquiritin is one of the flavone compounds found in licorice. It has been found to help lighten skin by preventing tyrosinase from reacting with tyrosine. When the two react, protein is converted to melanin. Melanin is the substance in your body that gives your features pigmentation.

Licorice root is native to Southern Europe and Asia. It has been used in traditional Chinese medicine to help with respiratory issues.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Pentylene Glycol (1,2-pentanediol) is a multitasking little diol with three main roles in a formula:

Research on alkanediols (the family pentylene glycol belongs to) show they work by disrupting microbial cell membranes. This disruption helps the primary preservative system in a product work more effectively at lower doses.

On the safety side, the Cosmetic Ingredient Review Expert Panel has concluded this ingredient to be safe as used in current cosmetic practices + concentrations.

Typical use levels in a formula run about 1-5%.

We don't have a description for Potassium Chloride yet.

Sodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity.

In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface.

Interestingly, the size of the molecule affects its behavior:

Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.

Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.

You'll typically see concentrations between 0.1-2% for this ingredient.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

Similar Comparisons

The reference edit

Ingredients, questions
& further reading.

Connected source records selected through this article’s public topic index.

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Formula cabinet

Ingredients & structured notes

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Product index

Related product references

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Comparison edit

Read side by side