Peptide Skincare & BeautySkin science and ingredient guides

Skin science article

Mary Kay TimeWise Repair Volu-Firm® Advanced Lifting Serum Versus The Ordinary Argireline Solution 10%

Mary Kay TimeWise Repair Volu-Firm® Advanced Lifting Serum Versus The Ordinary Argireline Solution 10% This anti-aging serum is formulated around Tripeptide-1 to soften the look of wrinkles. This anti-aging serum is formulated around Acetyl Hexapeptide-8 to so

Mary Kay TimeWise Repair Volu-Firm® Advanced Lifting Serum Versus The Ordinary Argireline Solution 10%

This anti-aging serum is formulated around Tripeptide-1 to soften the look of wrinkles.

This anti-aging serum is formulated around Acetyl Hexapeptide-8 to soften the look of wrinkles.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Cyclopentasiloxane

Water

Silica

Glycerin

PEG-10 Dimethicone

Dimethicone

Polymethylsilsesquioxane

Polysilicone-11

Pentylene Glycol

Hdi/Trimethylol Hexyllactone Crosspolymer

Phenoxyethanol

Butylene Glycol

Ammonium Acryloyldimethyltaurate/Vp Copolymer

Vp/Va Copolymer

Polysorbate 40

Sorbitol

Mica

Caprylyl Glycol

Chlorphenesin

Alpinia Galanga Leaf Extract

Menthyl Lactate

Hydroxypropyl Cyclodextrin

Sodium Chloride

Secale Cereale Seed Extract

Centella Asiatica Meristem Cell Culture

Cyclohexasiloxane

Disodium EDTA

Triethanolamine

Dihydroxy Methylchromone

Pisum Sativum Extract

Schisandra Chinensis Fruit Extract

Xanthan Gum

Caprylic Acid

Caprylic/Capric Triglyceride

Sodium Citrate

Tin Oxide

Iodopropynyl Butylcarbamate

Cyclodextrin

Maltodextrin

Alteromonas Ferment Filtrate

Tocopherol

Dextran

Tripeptide-1

CI 77891

Cyclopentasiloxane, Water, Silica, Glycerin, PEG-10 Dimethicone, Dimethicone, Polymethylsilsesquioxane, Polysilicone-11, Pentylene Glycol, Hdi/Trimethylol Hexyllactone Crosspolymer, Phenoxyethanol, Butylene Glycol, Ammonium Acryloyldimethyltaurate/Vp Copolymer, Vp/Va Copolymer, Polysorbate 40, Sorbitol, Mica, Caprylyl Glycol, Chlorphenesin, Alpinia Galanga Leaf Extract, Menthyl Lactate, Hydroxypropyl Cyclodextrin, Sodium Chloride, Secale Cereale Seed Extract, Centella Asiatica Meristem Cell Culture, Cyclohexasiloxane, Disodium EDTA, Triethanolamine, Dihydroxy Methylchromone, Pisum Sativum Extract, Schisandra Chinensis Fruit Extract, Xanthan Gum, Caprylic Acid, Caprylic/Capric Triglyceride, Sodium Citrate, Tin Oxide, Iodopropynyl Butylcarbamate, Cyclodextrin, Maltodextrin, Alteromonas Ferment Filtrate, Tocopherol, Dextran, Tripeptide-1, CI 77891

Propanediol

Acetyl Hexapeptide-8

Trisodium Ethylenediamine Disuccinate

Gellan Gum

Isoceteth-20

Dimethyl Isosorbide

Potassium Sorbate

Water, Propanediol, Acetyl Hexapeptide-8, Trisodium Ethylenediamine Disuccinate, Gellan Gum, Sodium Chloride, Isoceteth-20, Dimethyl Isosorbide, Potassium Sorbate, Phenoxyethanol, Chlorphenesin

Reviews

Be the first to review

Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Chlorphenesin is a synthetic preservative. It helps protect a product against bacteria in order to extend shelf life. In most cases, Chlorphenesin is paired with other preservatives such as phenoxyethanol and caprylyl glycol.

Chlorphenesin is a biocide. This means it is able to help fight the microorganisms on our skin. It is also able to fight odor-releasing bacteria.

Chlorphenesin is soluble in both water and glycerin.

Studies show Chlorphenesin is easily absorbed by our skin. You should speak with a skincare professional if you have concerns about using Chlorphenesin.

Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).

It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.

On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.

Another perk of this ingredient is that it stays functional across a wide pH range (3-10).

You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.

Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.

Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.

Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.

Chances are, you eat sodium chloride every day. Sodium Chloride is also known as table salt. This ingredient has many purposes in skincare: thickener, emulsifier, and exfoliator.

You'll most likely find this ingredient in cleansers where it is used to create a gel-like texture. As an emulsifier, it also prevents ingredients from separating.

You might see people debate whether Sodium Chloride is comedogenic, but there actually haven't been any comedogenic tests done on it. Either way, the overall formulation of a product matters a lot more than any single ingredient.

You might see this ingredient used in scrubs as a primary exfoliating ingredient.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

Similar Comparisons

The reference edit

Ingredients, questions
& further reading.

Connected source records selected through this article’s public topic index.

01

Formula cabinet

Ingredients & structured notes

Ingredient index

Ingredients Explained

  1. 01These ingredients are found in both products.
  2. 02Ingredients higher up in an ingredient list are typically present in a larger amount.
  3. 031,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse.
  4. 04It is a:
  5. 05Humectant, drawing moisture into the skin
  6. 06Emollient, helping to soften skin
  7. 07Solvent, dispersing and stabilizing formulas
  8. 08Preservative booster, enhancing the antimicrobial activity of other preservatives
  9. 09Acrylates/C10-30 Alkyl Acrylate Crosspolymer is a synthetic polymer. It is used to thicken, emulsify, and improve the texture of products.
  10. 10As an emulsifier, it helps stabilize oil-in-water emulsions to give products an elegant feel when applied.
  11. 11It can also form a thin protective film on skin. One study found that a formula using this polymer helped slow down how quickly other ingredients (like DEET) were absorbed through skin.
  12. 12A 2024 study of over 1,300 patients confirmed that sensitization to this ingredient is rare. It is also non-mutagenic and has a clean track record.
  13. 13Dimethicone is a type of synthetic silicone created from natural materials such as quartz. It is also known as polydimethylsiloxane.
  14. 14What it does:
  15. 15Dimethicone comes in different viscosities:
  16. 16Depending on the viscosity, dimethicone has different properties.
  17. 17Ingredients lists don't always show which type is used, so we recommend reaching out to the brand if you have questions about the viscosity.
  18. 18This ingredient is unlikely to cause irritation because it does not get absorbed into skin. However, people with silicone allergies should be careful about using this ingredient.
  19. 19Note: Dimethicone may contribute to pilling. This is because it is not oil or water soluble, so pilling may occur when layered with products. When mixed with heavy oils in a formula, the outcome is also quite greasy.
  20. 20Disodium EDTA is a chelating agent. It grabs onto and deactivates metal ions that sneak into your products from water, packaging, or air.
Source · skinsort.com
02

Product index

Related product references

Product

Equate Beauty Eye Lifting Serum

Equate Beauty Eye Lifting Serum Equate Beauty Eye Lifting Serum ingredients explained: Water, Dimethicone, Dimethicone Crosspolymer, Glycerin, Niacinamide, Butylene Glycol, Carbomer, Polyso…

Source: incidecoder.comView reference →
03

Comparison edit

Read side by side