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MediCube Deep Vita C Ampoule Versus Paula's Choice C15 Super Booster

MediCube Deep Vita C Ampoule Versus Paula's Choice C15 Super Booster This brightening ampoule is formulated around Ascorbic Acid and Glutathione to brighten dull-looking skin and fade the look of dark spots. This brightening serum is formulated around Ascorbic

MediCube Deep Vita C Ampoule Versus Paula's Choice C15 Super Booster

This brightening ampoule is formulated around Ascorbic Acid and Glutathione to brighten dull-looking skin and fade the look of dark spots.

This brightening serum is formulated around Ascorbic Acid and Ferulic Acid to brighten dull-looking skin and soften the look of wrinkles.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Ascorbic Acid

Butylene Glycol

Dipropylene Glycol

Propanediol

Dicaprylyl Carbonate

Propylene Glycol Dicaprylate

Isopropyl Oleate

Isopropyl Sorbate

Polysorbate 60

Glutathione

Glycerin

Alpha-Ionol

Glyceryl Stearate

Panthenol

Citric Acid

Chitosan

Pullulan

Sodium Gluconate

Sodium Hyaluronate

Helianthus Annuus Seed Oil

Dimethicone

Ethylhexyl Methoxycinnamate

Cetrimonium Chloride

Sodium Chloride

Vigna Radiata Seed Extract

Citrus Grandis Fruit Extract

Eclipta Prostrata Extract

Glycine Soja Seed Extract

Beta-Carotene

Daucus Carota Sativa Seed Oil

Curcuma Longa Root Extract

Terminalia Ferdinandiana Fruit Extract

Beta-Glucan

Betula Alba Bark Extract

Sophora Flavescens Root Extract

Sodium

Water, Ascorbic Acid, Butylene Glycol, Dipropylene Glycol, Propanediol, Dicaprylyl Carbonate, Propylene Glycol Dicaprylate, Isopropyl Oleate, Isopropyl Sorbate, Polysorbate 60, Glutathione, Glycerin, Alpha-Ionol, Glyceryl Stearate, Panthenol, Citric Acid, Chitosan, Pullulan, Sodium Gluconate, Sodium Hyaluronate, Helianthus Annuus Seed Oil, Dimethicone, Ethylhexyl Methoxycinnamate, Cetrimonium Chloride, Sodium Chloride, Vigna Radiata Seed Extract, Citrus Grandis Fruit Extract, Eclipta Prostrata Extract, Glycine Soja Seed Extract, Beta-Carotene, Daucus Carota Sativa Seed Oil, Curcuma Longa Root Extract, Terminalia Ferdinandiana Fruit Extract, Beta-Glucan, Betula Alba Bark Extract, Sophora Flavescens Root Extract, Sodium

Ethoxydiglycol

Sodium Hydroxide

PPG-26-Buteth-26

PEG-40 Hydrogenated Castor Oil

Bisabolol

Ferulic Acid

Sodium Phytate

Decylene Glycol

Tocopherol

1,2-Hexanediol

Sphingomonas Ferment Extract

Phenoxyethanol

Water, Ascorbic Acid, Dipropylene Glycol, Propanediol, Glycerin, Ethoxydiglycol, Sodium Hydroxide, PPG-26-Buteth-26, PEG-40 Hydrogenated Castor Oil, Bisabolol, Ferulic Acid, Sodium Phytate, Decylene Glycol, Tocopherol, 1,2-Hexanediol, Sphingomonas Ferment Extract, Phenoxyethanol

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Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Ascorbic Acid is is pure Vitamin C and is the biologically active form used directly by skin.

Not only is vitamin C great for your overall health and immune system, but it also has plenty of benefits for your skin. It is best supported by academic literature for:

Topical vitamin C has been shown to help neutralize oxidative stress from UV and pollution, helping to improve photoaging and hyperpigmentation when used consistently.

One clinical study found that using 5% topical vitamin C for six months improved signs of photodamaged skin, both on the surface and in the deeper structural layers of the skin.

While vitamin C doesn’t replace sunscreen, studies show it can boost photoprotection when combined with Vitamin E and ferulic acid. These two ingredients help improve stability and protective effects.

The big downside of this ingredient is formulation difficulty. Vitamin C is prone to oxidation and doesn't penetrate the skin unless formulated correctly. Research found that vitamin C absorbs into the skin best at a low pH (< 3.5) with about 20% being the upper limit for effective absorption.

Skin levels can saturate after repeated application; this means your skin won’t keep absorbing more once it’s full of vitamin C. This is why more isn’t always better with vitamin C and why very high concentrations don’t necessarily give extra benefits.

Ascorbic acid generally works well with many skincare ingredients but can be irritating when combined with other active ingredients. Strong oxidizing acne treatments like benzoyl peroxide can reduce the effectiveness of vitamin C if they are used at the same time; they are often recommended for use at different times of day.

Read more about other types of Vitamin C:

Foods rich with vitamin C include oranges, strawberries, broccoli, bell peppers, and more. When consuming Vitamin C, your skin receives a portion of the nutrients.

Dipropylene Glycol is a synthetically created humectant, stabilizer, and solvent.

This ingredient helps:

Dipropylene glycol is technically an alcohol, but it belongs to the glycol family (often considered part of the ‘good’ alcohols). This means it is hydrating and gentle on skin unlike drying solvent alcohols like denatured alcohol.

As a masking agent, Dipropylene Glycol can be used to cover the smell of other ingredients. However, it does not have a scent.

Studies show Dipropylene Glycol is considered safe to use in skincare.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Propanediol is an all-star ingredient. It softens, hydrates, and smooths the skin.

It’s often used to:

Propanediol is not likely to cause sensitivity and considered safe to use. It is derived from corn or petroleum with a clear color and no scent.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

Similar Comparisons

The reference edit

Ingredients, questions
& further reading.

Connected source records selected through this article’s public topic index.

01

Formula cabinet

Ingredients & structured notes

Ingredient index

Ingredients Explained

  1. 01These ingredients are found in both products.
  2. 02Ingredients higher up in an ingredient list are typically present in a larger amount.
  3. 03Caprylic/Capric Triglyceride (aka MCT Oil) is a lightweight emollient, solvent, and texture enhancer. It is considered a skin-softener by helping to prevent moisture loss.
  4. 04Though it behaves like an oil, it is not technically one due to its chemical composition. One perk of this ingredient is that it is very stable, resistant to oxidation, and unlikely to go rancid.
  5. 05In practice, that translates to a long shelf life and a consistently elegant skin feel.
  6. 06While there is an assumption Caprylic Triglyceride can clog pores due to it being derived from coconut oil, there is no research supporting this. Just patch test if you have concerns.
  7. 07Fractionated coconut oil and MCT Oil are both listed as Caprylic/Capric Triglyceride according to INCI. This is because INCI names are based on the ingredient’s final chemical composition and not its marketing name or source.
  8. 08This ingredient is treated as the gold standard fungal acne safe oil. Even though it is coconut derived, the problematic lauric acid is stripped out.
  9. 09This leaves just caprylic (C8) and capric (C10) acid. These chain lengths actually trend antifungal; a 2020 study found caprylic acid was enough to disrupt Malassezia furfur cell membrane, with a caprylic acid derivative damaging membrane structures…
  10. 10Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
  11. 11Topically, glycerin does several things at once:
  12. 12Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
  13. 13Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
  14. 14This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
  15. 15Just know very high concentrations (>40%) can feel tacky in low humidity.
  16. 16Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
  17. 17Hydroxyacetophenone is a small phenolic molecule that earns its place in a formulas as an antioxidant and preservative booster.
  18. 18As a phenol, it is able to neutralize free radicals to protect both the product and the skin from oxidative stress.
  19. 19Though it can't kill microbes on its own, it works as a good supporting agent when combined with other preservatives like Phenoxyethanol or 1,2-Hexanediol.
  20. 20This ingredient naturally occurs as piceol in Norwegian spruce needles (~0.4-1.1% dry weight and in cloudberries). Though the cosmetic-grade material is synthesized for purity and consistency.
Source · skinsort.com
02

Product index

Related product references

Product

Paula's Choice BHA 9 Treatment

Paula's Choice BHA 9 Treatment Paula's Choice BHA 9 Treatment ingredients explained: Propylene Glycol⁠, PEG-75 Stearate⁠, PEG-8⁠, Water⁠, Salicylic Acid⁠, Glycerin⁠, Avena Sativa (Oat) Kern…

Source: incidecoder.comView reference →
03

Comparison edit

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