Skin science article
MediCube Deep Vita C Ampoule Versus Paula's Choice C15 Super Booster
MediCube Deep Vita C Ampoule Versus Paula's Choice C15 Super Booster This brightening ampoule is formulated around Ascorbic Acid and Glutathione to brighten dull-looking skin and fade the look of dark spots. This brightening serum is formulated around Ascorbic
MediCube Deep Vita C Ampoule Versus Paula's Choice C15 Super Booster
This brightening ampoule is formulated around Ascorbic Acid and Glutathione to brighten dull-looking skin and fade the look of dark spots.
This brightening serum is formulated around Ascorbic Acid and Ferulic Acid to brighten dull-looking skin and soften the look of wrinkles.
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Ascorbic Acid
Butylene Glycol
Dipropylene Glycol
Propanediol
Dicaprylyl Carbonate
Propylene Glycol Dicaprylate
Isopropyl Oleate
Isopropyl Sorbate
Polysorbate 60
Glutathione
Glycerin
Alpha-Ionol
Glyceryl Stearate
Panthenol
Citric Acid
Chitosan
Pullulan
Sodium Gluconate
Sodium Hyaluronate
Helianthus Annuus Seed Oil
Dimethicone
Ethylhexyl Methoxycinnamate
Cetrimonium Chloride
Sodium Chloride
Vigna Radiata Seed Extract
Citrus Grandis Fruit Extract
Eclipta Prostrata Extract
Glycine Soja Seed Extract
Beta-Carotene
Daucus Carota Sativa Seed Oil
Curcuma Longa Root Extract
Terminalia Ferdinandiana Fruit Extract
Beta-Glucan
Betula Alba Bark Extract
Sophora Flavescens Root Extract
Sodium
Water, Ascorbic Acid, Butylene Glycol, Dipropylene Glycol, Propanediol, Dicaprylyl Carbonate, Propylene Glycol Dicaprylate, Isopropyl Oleate, Isopropyl Sorbate, Polysorbate 60, Glutathione, Glycerin, Alpha-Ionol, Glyceryl Stearate, Panthenol, Citric Acid, Chitosan, Pullulan, Sodium Gluconate, Sodium Hyaluronate, Helianthus Annuus Seed Oil, Dimethicone, Ethylhexyl Methoxycinnamate, Cetrimonium Chloride, Sodium Chloride, Vigna Radiata Seed Extract, Citrus Grandis Fruit Extract, Eclipta Prostrata Extract, Glycine Soja Seed Extract, Beta-Carotene, Daucus Carota Sativa Seed Oil, Curcuma Longa Root Extract, Terminalia Ferdinandiana Fruit Extract, Beta-Glucan, Betula Alba Bark Extract, Sophora Flavescens Root Extract, Sodium
Ethoxydiglycol
Sodium Hydroxide
PPG-26-Buteth-26
PEG-40 Hydrogenated Castor Oil
Bisabolol
Ferulic Acid
Sodium Phytate
Decylene Glycol
Tocopherol
1,2-Hexanediol
Sphingomonas Ferment Extract
Phenoxyethanol
Water, Ascorbic Acid, Dipropylene Glycol, Propanediol, Glycerin, Ethoxydiglycol, Sodium Hydroxide, PPG-26-Buteth-26, PEG-40 Hydrogenated Castor Oil, Bisabolol, Ferulic Acid, Sodium Phytate, Decylene Glycol, Tocopherol, 1,2-Hexanediol, Sphingomonas Ferment Extract, Phenoxyethanol
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Alternatives
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Ascorbic Acid is is pure Vitamin C and is the biologically active form used directly by skin.
Not only is vitamin C great for your overall health and immune system, but it also has plenty of benefits for your skin. It is best supported by academic literature for:
Topical vitamin C has been shown to help neutralize oxidative stress from UV and pollution, helping to improve photoaging and hyperpigmentation when used consistently.
One clinical study found that using 5% topical vitamin C for six months improved signs of photodamaged skin, both on the surface and in the deeper structural layers of the skin.
While vitamin C doesn’t replace sunscreen, studies show it can boost photoprotection when combined with Vitamin E and ferulic acid. These two ingredients help improve stability and protective effects.
The big downside of this ingredient is formulation difficulty. Vitamin C is prone to oxidation and doesn't penetrate the skin unless formulated correctly. Research found that vitamin C absorbs into the skin best at a low pH (< 3.5) with about 20% being the upper limit for effective absorption.
Skin levels can saturate after repeated application; this means your skin won’t keep absorbing more once it’s full of vitamin C. This is why more isn’t always better with vitamin C and why very high concentrations don’t necessarily give extra benefits.
Ascorbic acid generally works well with many skincare ingredients but can be irritating when combined with other active ingredients. Strong oxidizing acne treatments like benzoyl peroxide can reduce the effectiveness of vitamin C if they are used at the same time; they are often recommended for use at different times of day.
Read more about other types of Vitamin C:
Foods rich with vitamin C include oranges, strawberries, broccoli, bell peppers, and more. When consuming Vitamin C, your skin receives a portion of the nutrients.
Dipropylene Glycol is a synthetically created humectant, stabilizer, and solvent.
This ingredient helps:
Dipropylene glycol is technically an alcohol, but it belongs to the glycol family (often considered part of the ‘good’ alcohols). This means it is hydrating and gentle on skin unlike drying solvent alcohols like denatured alcohol.
As a masking agent, Dipropylene Glycol can be used to cover the smell of other ingredients. However, it does not have a scent.
Studies show Dipropylene Glycol is considered safe to use in skincare.
Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Propanediol is an all-star ingredient. It softens, hydrates, and smooths the skin.
It’s often used to:
Propanediol is not likely to cause sensitivity and considered safe to use. It is derived from corn or petroleum with a clear color and no scent.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!