Skin science article
Naturium Multi-Peptide Moisturizer Versus Bliss Drench & Quench For Dry Skin Rich Water Cream For All-Day Moisture
Naturium Multi-Peptide Moisturizer Versus Bliss Drench & Quench For Dry Skin Rich Water Cream For All-Day Moisture This anti-aging moisturizer is formulated around Palmitoyl Tripeptide-5 and Palmitoyl Tripeptide-1 to soften the look of wrinkles. What's inside
Naturium Multi-Peptide Moisturizer Versus Bliss Drench & Quench For Dry Skin Rich Water Cream For All-Day Moisture
This anti-aging moisturizer is formulated around Palmitoyl Tripeptide-5 and Palmitoyl Tripeptide-1 to soften the look of wrinkles.
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Glycerin
Dimethicone
Simmondsia Chinensis Seed Oil
Squalane
Glyceryl Stearate
Cetyl Alcohol
Niacinamide
Stearyl Alcohol
Palmitoyl Tripeptide-5
Pantolactone
Palmitoyl Tripeptide-1
Palmitoyl Tetrapeptide-7
Hydrolyzed Plukenetia Volubilis Seed Extract
Dunaliella Salina Extract
Sodium Hyaluronate
3-O-Ethyl Ascorbic Acid
Panthenol
Caryodendron Orinocense Seed Oil
Honokiol
Magnolol
Palmitic Acid
Sorbitan Oleate
Aluminum Starch Octenylsuccinate
Hydroxyacetophenone
Stearic Acid
Acrylamide/Sodium Acryloyldimethyltaurate Copolymer
Polyglyceryl-6 Laurate
1,2-Hexanediol
Boron Nitride
Caprylyl Glycol
Polyglyceryl-10 Oleate
Isohexadecane
Butylene Glycol
Chlorphenesin
Acrylates/C10-30 Alkyl Acrylate Crosspolymer
Tocopheryl Acetate
Polysorbate 80
Sorbitan Palmitate
Sodium Hydroxide
Sodium Benzoate
Carbomer
Sodium Lactate
Phenoxyethanol
Polysorbate 20
Citric Acid
Ethylhexylglycerin
Potassium Sorbate
Water, Glycerin, Dimethicone, Simmondsia Chinensis Seed Oil, Squalane, Glyceryl Stearate, Cetyl Alcohol, Niacinamide, Stearyl Alcohol, Palmitoyl Tripeptide-5, Pantolactone, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Hydrolyzed Plukenetia Volubilis Seed Extract, Dunaliella Salina Extract, Sodium Hyaluronate, 3-O-Ethyl Ascorbic Acid, Panthenol, Caryodendron Orinocense Seed Oil, Honokiol, Magnolol, Palmitic Acid, Sorbitan Oleate, Aluminum Starch Octenylsuccinate, Hydroxyacetophenone, Stearic Acid, Acrylamide/Sodium Acryloyldimethyltaurate Copolymer, Polyglyceryl-6 Laurate, 1,2-Hexanediol, Boron Nitride, Caprylyl Glycol, Polyglyceryl-10 Oleate, Isohexadecane, Butylene Glycol, Chlorphenesin, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Tocopheryl Acetate, Polysorbate 80, Sorbitan Palmitate, Sodium Hydroxide, Sodium Benzoate, Carbomer, Sodium Lactate, Phenoxyethanol, Polysorbate 20, Citric Acid, Ethylhexylglycerin, Potassium Sorbate
Cyclopentasiloxane
Propanediol
Saccharide Isomerate
Caprylic/Capric Triglyceride
Tocopherol
Tetrahexyldecyl Ascorbate
Sodium Hyaluronate Crosspolymer
Hydrolyzed Sodium Hyaluronate
Sodium Acetylated Hyaluronate
Glycine Soja Oil
Helianthus Annuus Seed Oil
Passiflora Edulis Seed Oil
Chamomilla Recutita Flower Extract
Passiflora Incarnata Fruit Extract
Rosa Centifolia Flower Extract
Silybum Marianum Extract
Ahnfeltiopsis Concinna Extract
Commiphora Myrrha Resin Extract
Amylopectin
Ceramide Ng
Sodium Levulinate
Caprylyl Methicone
Methyl Palmitate
Hydrogenated Polyisobutene
Silica
Pentylene Glycol
Propylene Glycol
PEG-10 Dimethicone
Dimethicone/Vinyl Dimethicone Crosspolymer
Sodium Citrate
Sodium Dehydroacetate
Sodium Chloride
Benzyl Alcohol
Water, Cyclopentasiloxane, Glycerin, Dimethicone, Propanediol, Saccharide Isomerate, Caprylic/Capric Triglyceride, Tocopherol, Tetrahexyldecyl Ascorbate, Sodium Hyaluronate, Sodium Hyaluronate Crosspolymer, Hydrolyzed Sodium Hyaluronate, Sodium Acetylated Hyaluronate, Glycine Soja Oil, Helianthus Annuus Seed Oil, Passiflora Edulis Seed Oil, Chamomilla Recutita Flower Extract, Passiflora Incarnata Fruit Extract, Rosa Centifolia Flower Extract, Silybum Marianum Extract, Ahnfeltiopsis Concinna Extract, Commiphora Myrrha Resin Extract, Amylopectin, Ceramide Ng, Sodium Levulinate, Caprylyl Methicone, Methyl Palmitate, Hydrogenated Polyisobutene, Silica, Pentylene Glycol, Propylene Glycol, PEG-10 Dimethicone, Dimethicone/Vinyl Dimethicone Crosspolymer, Sodium Citrate, Phenoxyethanol, Ethylhexylglycerin, Potassium Sorbate, Sodium Benzoate, Sodium Dehydroacetate, Chlorphenesin, Citric Acid, Sodium Chloride, Benzyl Alcohol
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Alternatives
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Chlorphenesin is a synthetic preservative. It helps protect a product against bacteria in order to extend shelf life. In most cases, Chlorphenesin is paired with other preservatives such as phenoxyethanol and caprylyl glycol.
Chlorphenesin is a biocide. This means it is able to help fight the microorganisms on our skin. It is also able to fight odor-releasing bacteria.
Chlorphenesin is soluble in both water and glycerin.
Studies show Chlorphenesin is easily absorbed by our skin. You should speak with a skincare professional if you have concerns about using Chlorphenesin.
Citric Acid is an alpha hydroxy acid (AHA) naturally found in citrus fruits like oranges, lemons, and limes.
Like other AHAs, citric acid can exfoliate skin by breaking down the bonds that hold dead skin cells together. This helps reveal smoother and brighter skin underneath.
However, this exfoliating effect only happens at high concentrations (20%) which can be hard to find in cosmetic products.
Due to this, citric acid is usually included in small amounts as a pH adjuster. This helps keep products slightly more acidic and compatible with skin's natural pH.
In skincare formulas, citric acid can:
While it can provide some skin benefits, research shows lactic acid and glycolic acid are generally more effective and less irritating exfoliants.
Most citric acid used in skincare today is made by fermenting sugars (usually from molasses). This synthetic version is identical to the natural citrus form but easier to stabilize and use in formulations.
Rosacea skin has a lower threshold for acids generally, with 62.5% of rosacea subjects in one study reacting to lactic acid in a sting test. This is why we mark citric acid as a potential rosacea trigger.
However, this ingredient shows up as a pH adjuster or chelator at roughly 0.1-1% in many products. These low levels are unlikely to be an issue for rosacea skin and becomes a potential trigger at exfoliating concentrations (20%). Because everybody's skin is unique, we recommend a patch test if you are unsure.
Dimethicone is a type of synthetic silicone created from natural materials such as quartz. It is also known as polydimethylsiloxane.
What it does:
Dimethicone comes in different viscosities:
Depending on the viscosity, dimethicone has different properties.
Ingredients lists don't always show which type is used, so we recommend reaching out to the brand if you have questions about the viscosity.
This ingredient is unlikely to cause irritation because it does not get absorbed into skin. However, people with silicone allergies should be careful about using this ingredient.
Note: Dimethicone may contribute to pilling. This is because it is not oil or water soluble, so pilling may occur when layered with products. When mixed with heavy oils in a formula, the outcome is also quite greasy.
Ethylhexylglycerin is created from glycerin. It is a multitasker ingredient that:
The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.
Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.
Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).
It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.
On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.
Another perk of this ingredient is that it stays functional across a wide pH range (3-10).
You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.
Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.
Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.
Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.
Potassium Sorbate is a preservative used to prevent yeast and mold in products. It is commonly found in both cosmetic and food products.
This ingredient comes from potassium salt derived from sorbic acid. Sorbic acid is a natural antibiotic and effective against fungus.
Both potassium sorbate and sorbic acid can be found in baked goods, cheeses, dried meats, dried fruit, ice cream, pickles, wine, yogurt, and more.
You'll often find this ingredient used with other preservatives.
Sodium Benzoate is a preservative. It's used in both cosmetic and food products to inhibit the growth of mold and bacteria. It is typically produced synthetically.
Both the US FDA and EU Health Committee have approved the use of sodium benzoate. In the US, levels of 0.1% (of the total product) are allowed.
Sodium benzoate works as a preservative by inhibiting the growth of bacteria inside of cells. It prevents the cell from fermenting a type of sugar using an enzyme called phosphofructokinase.
It is the salt of benzoic acid. Foods containing sodium benzoate include soda, salad dressings, condiments, fruit juices, wines, and snack foods.
Studies for using ascorbic acid and sodium benzoate in cosmetics are lacking, especially in skincare routines with multiple steps.
We always recommend speaking with a professional, such as a dermatologist, if you have any concerns.
Sodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity.
In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface.
Interestingly, the size of the molecule affects its behavior:
Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.
Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.
You'll typically see concentrations between 0.1-2% for this ingredient.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!