Naturium Multi-Peptide Moisturizer Versus Isntree C-Niacin Toning Cream

Naturium Multi-Peptide Moisturizer Versus Isntree C-Niacin Toning Cream

This anti-aging moisturizer is formulated around Palmitoyl Tripeptide-5 and Palmitoyl Tripeptide-1 to soften the look of wrinkles.

This brightening moisturizer is formulated around Hippophae Rhamnoides Fruit Extract and Niacinamide to brighten dull-looking skin and fade the look of dark spots.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Glycerin

Dimethicone

Simmondsia Chinensis Seed Oil

Squalane

Glyceryl Stearate

Cetyl Alcohol

Niacinamide

Stearyl Alcohol

Palmitoyl Tripeptide-5

Pantolactone

Palmitoyl Tripeptide-1

Palmitoyl Tetrapeptide-7

Hydrolyzed Plukenetia Volubilis Seed Extract

Dunaliella Salina Extract

Sodium Hyaluronate

3-O-Ethyl Ascorbic Acid

Panthenol

Caryodendron Orinocense Seed Oil

Honokiol

Magnolol

Palmitic Acid

Sorbitan Oleate

Aluminum Starch Octenylsuccinate

Hydroxyacetophenone

Stearic Acid

Acrylamide/Sodium Acryloyldimethyltaurate Copolymer

Polyglyceryl-6 Laurate

1,2-Hexanediol

Boron Nitride

Caprylyl Glycol

Polyglyceryl-10 Oleate

Isohexadecane

Butylene Glycol

Chlorphenesin

Acrylates/C10-30 Alkyl Acrylate Crosspolymer

Tocopheryl Acetate

Polysorbate 80

Sorbitan Palmitate

Sodium Hydroxide

Sodium Benzoate

Carbomer

Sodium Lactate

Phenoxyethanol

Polysorbate 20

Citric Acid

Ethylhexylglycerin

Potassium Sorbate

Water, Glycerin, Dimethicone, Simmondsia Chinensis Seed Oil, Squalane, Glyceryl Stearate, Cetyl Alcohol, Niacinamide, Stearyl Alcohol, Palmitoyl Tripeptide-5, Pantolactone, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Hydrolyzed Plukenetia Volubilis Seed Extract, Dunaliella Salina Extract, Sodium Hyaluronate, 3-O-Ethyl Ascorbic Acid, Panthenol, Caryodendron Orinocense Seed Oil, Honokiol, Magnolol, Palmitic Acid, Sorbitan Oleate, Aluminum Starch Octenylsuccinate, Hydroxyacetophenone, Stearic Acid, Acrylamide/Sodium Acryloyldimethyltaurate Copolymer, Polyglyceryl-6 Laurate, 1,2-Hexanediol, Boron Nitride, Caprylyl Glycol, Polyglyceryl-10 Oleate, Isohexadecane, Butylene Glycol, Chlorphenesin, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Tocopheryl Acetate, Polysorbate 80, Sorbitan Palmitate, Sodium Hydroxide, Sodium Benzoate, Carbomer, Sodium Lactate, Phenoxyethanol, Polysorbate 20, Citric Acid, Ethylhexylglycerin, Potassium Sorbate

Hippophae Rhamnoides Fruit Extract

Pentylene Glycol

Ethylhexyl Palmitate

Caprylic/Capric Triglyceride

Moringa Oleifera Seed Oil

Lycium Barbarum Fruit Extract

Euterpe Oleracea Fruit Extract

Myrciaria Dubia Fruit Extract

Hippophae Rhamnoides Oil

Beta-Glucan

Olea Europaea Fruit Oil

Carthamus Tinctorius Seed Oil

Phytosphingosine

Polyacrylic Acid

Cyanocobalamin

Sodium Ascorbyl Phosphate

Biotin

Pyridoxine

Glyceryl Arachidonate

Mangifera Indica Seed Butter

Sodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer

Ceramide NP

Argania Spinosa Kernel Oil

Macadamia Ternifolia Seed Oil

Polyglyceryl-10 Stearate

Hydroxypropyl Guar

Glyceryl Acrylate/Acrylic Acid Copolymer

Arginine

Sucrose Distearate

Pvm/Ma Copolymer

Disodium EDTA

Thiamine Hcl

Hydrogenated Lecithin

Glyceryl Linolenate

Ethyl Hexanediol

Retinyl Palmitate

Hippophae Rhamnoides Fruit Extract, Butylene Glycol, Pentylene Glycol, Water, 1,2-Hexanediol, Niacinamide, Ethylhexyl Palmitate, Caprylic/Capric Triglyceride, Moringa Oleifera Seed Oil, Lycium Barbarum Fruit Extract, Euterpe Oleracea Fruit Extract, Myrciaria Dubia Fruit Extract, Hippophae Rhamnoides Oil, Beta-Glucan, Olea Europaea Fruit Oil, Carthamus Tinctorius Seed Oil, Phytosphingosine, Polyacrylic Acid, Cyanocobalamin, Sodium Ascorbyl Phosphate, Biotin, Pyridoxine, Glyceryl Arachidonate, Mangifera Indica Seed Butter, Sodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Isohexadecane, Ceramide NP, Argania Spinosa Kernel Oil, Macadamia Ternifolia Seed Oil, Polyglyceryl-10 Stearate, Hydroxypropyl Guar, Panthenol, Carbomer, Glyceryl Acrylate/Acrylic Acid Copolymer, Arginine, Sucrose Distearate, Pvm/Ma Copolymer, Disodium EDTA, Glycerin, Thiamine Hcl, Hydrogenated Lecithin, Tocopheryl Acetate, Glyceryl Linolenate, Polysorbate 80, Ethyl Hexanediol, Retinyl Palmitate

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Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse.

It is a:

Humectant, drawing moisture into the skin

Emollient, helping to soften skin

Solvent, dispersing and stabilizing formulas

Preservative booster, enhancing the antimicrobial activity of other preservatives

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.

Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.

Carbomer is a synthetic thickening and gelling agent. It's basically the ingredient that gives a lot of serums, gels, creams, and sunscreens their smooth, non-sticky texture.

Although legally permitted at very high levels, carbomers are normally used at concentrations below 1%.

It also needs to be neutralized to actually thicken, and because it is a large molecule, it doesn't really penetrate the skin barrier.

Allergy-wise, the risk is very low. Clinical studies show carbomers have low potential for skin irritation/sensitization even at concentrations up to 100%.

A 2024 UK study patch-tested 1,302 patients and found true allergy to the parent group of carbomer to be rare with no confirmed relevant reactions.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Isohexadecane is added to enhance texture, emulsify, and to help cleanse. It is an isoparrafin. It is a component of petrolatum.

Due to its large size, Isohexadecane is not absorbed by the skin. Instead, it sits on top and acts as an emollient. Emollients help keep your skin soft and smooth by trapping moisture within.

Isohexadecane is often used in products designed to help oily skin. It is lightweight and non-greasy while helping to moisturize. When mixed with silicones, it gives a product a silky feel.

Niacinamide is a multitasking form of vitamin B3 that strengthens the skin barrier, reduces pores and dark spots, regulates oil, and improves signs of aging.

And the best part? It's gentle and well-tolerated by most skin types, including sensitive and reactive skin.

You might have heard of "niacin flush", or the reddening of skin that causes itchiness. Niacinamide has not been found to cause this.

In very rare cases, some individuals may not be able to tolerate niacinamide at all or experience an allergic reaction to it.

If you are experiencing flaking, irritation, and dryness with this ingredient, be sure to double check all your products as this ingredient can be found in all categories of skincare.

When incorporating niacinamide into your routine, look out for concentration amounts. Typically, 5% niacinamide provides benefits such as fading dark spots. However, if you have sensitive skin, it is better to begin with a smaller concentration.

When you apply niacinamide to your skin, your body converts it into nicotinamide adenine dinucleotide (NAD). NAD is an essential coenzyme that is already found in your cells as "fuel" and powers countless biological processes.

In your skin, NAD helps repair cell damage, produce new healthy cells, support collagen production, strengthen the skin barrier, and fight environmental stressors (like UV and pollution).

Our natural NAD levels start to decline with age, leading to slower skin repair, visible aging, and a weaker skin barrier. By providing your skin niacinamide, you're recharging your skin's NAD levels. This leads to stronger, healthier, and younger looking skin.

Another name for vitamin B3 is nicotinamide. This vitamin is water-soluble and our bodies don't store it. We obtain Vitamin B3 from either food or skincare. Meat, fish, wheat, yeast, and leafy greens contain vitamin B3.

The type of niacinamide used in skincare is synthetically created.

Panthenol is a common ingredient that helps hydrate and soothe the skin. It is found naturally in our skin and hair.

There are two forms of panthenol: D and L.

D-panthenol is also known as dexpanthenol. Most cosmetics use dexpanthenol or a mixture of D and L-panthenol.

Panthenol is famous due to its ability to go deeper into the skin's layers. Using this ingredient has numerous pros (and no cons):

Like hyaluronic acid, panthenol is a humectant. Humectants are able to bind and hold large amounts of water to keep skin hydrated.

This ingredient works well for wound healing. It works by increasing tissue in the wound and helps close open wounds.

Once oxidized, panthenol converts to pantothenic acid. Panthothenic acid is found in all living cells.

This ingredient is also referred to as pro-vitamin B5.

Polysorbate 80 is a synthetic surfactant and emulsifier derived from sorbitol and oleic acid.

It reduces the surface tension between oil and water phases to help them stay mixed and stable in a formulation. In other words, it prevents your formulas from separating into an oily mess.

The CIR Expert Panel has evaluated the scientific data and found this ingredient to be safe, non-irritating, and non-sensitizing at concentrations up to 5% (it's even approved by the FDA as an OTC eye drop ingredient).

Tocopheryl Acetate is a stable, shelf-friendly form of vitamin E.

Formulators love it because plain vitamin E oxidizes quickly once it hits air. This acetate version stays stable and resists going off, helping to extend a product's shelf life.

It's actually inactive on its own and works like a slow-release "storage" form; the enzymes in your skin called esterases gradually convert it into active vitamin E over time.

One in vivo study showed 5% of the acetate in the living layer of the epidermis converted to vitamin E after 5 days of application. This study also found the skin gained protection against UV damage even though the conversion was slow and small.

Once converted, vitamin E acts as a skin's main fat-soluble antioxidant that fights free radicals to protect skin from damage.

Topical vitamin E generally boosts the skin's photoprotection, and it reduced UV-damage in animal models.

This ingredient has some brightening potential but it's more of a prevention ingredient than spot-fader. Cell studies show it can slow down melanin production but it's worth noting that it's not the most powerful brightener out there.

Overall, it has a pretty solid safety profile and has been found to be non-irritating and non-comedogenic. Allergic reactions may happen but stay rare due to how widely the ingredient gets used.

The concentration will vary depending on the formula; industry data shows 0.1% in baby lotions, 3% in lipsticks, and 5% in foot powders. You can also find this ingredient at 100% in a pure vitamin E oil.

Most leave-on skincare keeps it at the lower end, often between 0.5-1%.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

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