Peptide Skincare & BeautySkin science and ingredient guides

Skin science article

Olay Super Serum Versus Medik8 Liquid Peptides

Olay Super Serum Versus Medik8 Liquid Peptides This smoothing serum is formulated around Niacinamide and Lactic Acid to refine skin texture and brighten dull-looking skin. This anti-aging serum is formulated around Carnosine and Palmitoyl Tripeptide-5 to softe

Olay Super Serum Versus Medik8 Liquid Peptides

This smoothing serum is formulated around Niacinamide and Lactic Acid to refine skin texture and brighten dull-looking skin.

This anti-aging serum is formulated around Carnosine and Palmitoyl Tripeptide-5 to soften the look of wrinkles and refine skin texture.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Glycerin

Dimethicone

Niacinamide

Lactic Acid

Polyacrylate Crosspolymer-6

Palmitoyl Pentapeptide-4

3-O-Ethyl Ascorbic Acid

Sodium Hyaluronate

Tocopheryl Acetate

Panthenol

Trehalose

PEG-11 Methyl Ether Dimethicone

Sodium Lactate

Mica

Titanium Dioxide

Sodium Benzoate

Parfum

Water, Glycerin, Dimethicone, Niacinamide, Lactic Acid, Polyacrylate Crosspolymer-6, Palmitoyl Pentapeptide-4, 3-O-Ethyl Ascorbic Acid, Sodium Hyaluronate, Tocopheryl Acetate, Panthenol, Trehalose, PEG-11 Methyl Ether Dimethicone, Sodium Lactate, Mica, Titanium Dioxide, Sodium Benzoate, Parfum

Butylene Glycol

Inulin

Alpha-Glucan Oligosaccharide

Carnosine

Carbomer

Polysorbate 20

Caprylyl Glycol

Phenoxyethanol

Hydroxypropyl Cyclodextrin

Dunaliella Salina Extract

Ethylhexylglycerin

Citric Acid

Palmitoyl Tripeptide-5

Acetyl Hexapeptide-8

Tetrapeptide-21

Pentapeptide-18

Palmitoyl Tripeptide-1

Pantolactone

Palmitoyl Tripeptide-38

Palmitoyl Tetrapeptide-7

Glyceryl Caprylate

Lactic Acid/Glycolic Acid Copolymer

Polyvinyl Alcohol

Phenylpropanol

Copper Palmitoyl Heptapeptide-14

Heptapeptide-15 Palmitate

Potassium Sorbate

Xanthan Gum

Water, Glycerin, Butylene Glycol, Inulin, Sodium Hyaluronate, Panthenol, Alpha-Glucan Oligosaccharide, Carnosine, Carbomer, Polysorbate 20, Caprylyl Glycol, Phenoxyethanol, Hydroxypropyl Cyclodextrin, Dunaliella Salina Extract, Ethylhexylglycerin, Citric Acid, Palmitoyl Tripeptide-5, Sodium Benzoate, Acetyl Hexapeptide-8, Tetrapeptide-21, Pentapeptide-18, Palmitoyl Tripeptide-1, Pantolactone, Palmitoyl Tripeptide-38, Palmitoyl Tetrapeptide-7, Glyceryl Caprylate, Lactic Acid/Glycolic Acid Copolymer, Polyvinyl Alcohol, Phenylpropanol, Copper Palmitoyl Heptapeptide-14, Heptapeptide-15 Palmitate, Potassium Sorbate, Xanthan Gum

Reviews

Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Panthenol is a common ingredient that helps hydrate and soothe the skin. It is found naturally in our skin and hair.

There are two forms of panthenol: D and L.

D-panthenol is also known as dexpanthenol. Most cosmetics use dexpanthenol or a mixture of D and L-panthenol.

Panthenol is famous due to its ability to go deeper into the skin's layers. Using this ingredient has numerous pros (and no cons):

Like hyaluronic acid, panthenol is a humectant. Humectants are able to bind and hold large amounts of water to keep skin hydrated.

This ingredient works well for wound healing. It works by increasing tissue in the wound and helps close open wounds.

Once oxidized, panthenol converts to pantothenic acid. Panthothenic acid is found in all living cells.

This ingredient is also referred to as pro-vitamin B5.

Sodium Benzoate is a preservative. It's used in both cosmetic and food products to inhibit the growth of mold and bacteria. It is typically produced synthetically.

Both the US FDA and EU Health Committee have approved the use of sodium benzoate. In the US, levels of 0.1% (of the total product) are allowed.

Sodium benzoate works as a preservative by inhibiting the growth of bacteria inside of cells. It prevents the cell from fermenting a type of sugar using an enzyme called phosphofructokinase.

It is the salt of benzoic acid. Foods containing sodium benzoate include soda, salad dressings, condiments, fruit juices, wines, and snack foods.

Studies for using ascorbic acid and sodium benzoate in cosmetics are lacking, especially in skincare routines with multiple steps.

We always recommend speaking with a professional, such as a dermatologist, if you have any concerns.

Sodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity.

In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface.

Interestingly, the size of the molecule affects its behavior:

Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.

Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.

You'll typically see concentrations between 0.1-2% for this ingredient.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

Similar Comparisons

The reference edit

Ingredients, questions
& further reading.

Connected source records selected through this article’s public topic index.

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Formula cabinet

Ingredients & structured notes

Ingredient index

Ingredients Explained

  1. 01These ingredients are found in both products.
  2. 02Ingredients higher up in an ingredient list are typically present in a larger amount.
  3. 03Carnosine is a dipeptide made from two amino acids.
  4. 04This ingredient helps:
  5. 05Glycation is the process of sugars binding to and damaging proteins. Too much sugar in our skin can lead to damaged collagen, contributing to factors of aging.
  6. 06Carnosine is water-soluble and is not able to travel deeper layers of skin. This leads to some doubt about whether it can boost collagen in skin, since collagen is located in the deeper layers of skin.
  7. 07Fun fact: Carnosine can be naturally found in our muscles and brain.
  8. 08Citric Acid is an alpha hydroxy acid (AHA) naturally found in citrus fruits like oranges, lemons, and limes.
  9. 09Like other AHAs, citric acid can exfoliate skin by breaking down the bonds that hold dead skin cells together. This helps reveal smoother and brighter skin underneath.
  10. 10However, this exfoliating effect only happens at high concentrations (20%) which can be hard to find in cosmetic products.
  11. 11Due to this, citric acid is usually included in small amounts as a pH adjuster. This helps keep products slightly more acidic and compatible with skin's natural pH.
  12. 12In skincare formulas, citric acid can:
  13. 13While it can provide some skin benefits, research shows lactic acid and glycolic acid are generally more effective and less irritating exfoliants.
  14. 14Most citric acid used in skincare today is made by fermenting sugars (usually from molasses). This synthetic version is identical to the natural citrus form but easier to stabilize and use in formulations.
  15. 15Rosacea skin has a lower threshold for acids generally, with 62.5% of rosacea subjects in one study reacting to lactic acid in a sting test. This is why we mark citric acid as a potential rosacea trigger.
  16. 16However, this ingredient shows up as a pH adjuster or chelator at roughly 0.1-1% in many products. These low levels are unlikely to be an issue for rosacea skin and becomes a potential trigger at exfoliating concentrations (20%). Because everybody's…
  17. 17Ethylhexylglycerin is created from glycerin. It is a multitasker ingredient that:
  18. 18The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure …
  19. 19Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.
  20. 20Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Source · skinsort.com
02

Product index

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Comparison edit

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