Skin science article
Paula's Choice Ceramide-Enriched Firming Eye Cream Versus Paula's Choice C5 Super Boost Eye Cream
Paula's Choice Ceramide-Enriched Firming Eye Cream Versus Paula's Choice C5 Super Boost Eye Cream This anti-aging eye moisturizer is formulated around Ceramide Ns and Palmitoyl Tripeptide-5 to soften the look of wrinkles and strengthen the skin barrier. This b
Paula's Choice Ceramide-Enriched Firming Eye Cream Versus Paula's Choice C5 Super Boost Eye Cream
This anti-aging eye moisturizer is formulated around Ceramide Ns and Palmitoyl Tripeptide-5 to soften the look of wrinkles and strengthen the skin barrier.
This brightening eye moisturizer is formulated around Ascorbyl Glucoside and 3-O-Ethyl Ascorbic Acid to brighten dull-looking skin and soften the look of wrinkles.
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Neopentyl Glycol Diheptanoate
Cetyl Alcohol
Butylene Glycol
Glycerin
Glyceryl Stearate
PEG-100 Stearate
Ammonium Acryloyldimethyltaurate/Vp Copolymer
Ascorbyl Glucoside
Potassium Cetyl Phosphate
Sodium Ascorbyl Phosphate
Bis-Diglyceryl Polyacyladipate-2
Polyglyceryl-10 Dioleate
Tetrahexyldecyl Ascorbate
Ceramide Ns
Ceramide EOP
Ceramide AP
Ceramide Eos
Ceramide NP
Palmitoyl Tripeptide-5
Acetyl Tetrapeptide-5
Caprooyl Phytosphingosine
Caprooyl Sphingosine
Cholesterol
Squalane
Retinol
Vitis Vinifera Seed Extract
Glycyrrhiza Glabra Root Extract
Punica Granatum Fruit Extract
Dunaliella Salina Extract
Pongamia Glabra Seed Oil
Tocopheryl Acetate
Allantoin
Bisabolol
Carnosine
Panthenol
Sodium PCA
Pullulan
Glyceryl Ascorbate
Behenic Acid
Dimethicone
Sodium Citrate
Sodium Polyacrylate
Caprylyl Glycol
Ethylhexyl Stearate
Ceteareth-25
Sodium Hydroxide
Trideceth-6
Propyl Gallate
Polysorbate 20
Disodium EDTA
Mica
Phenoxyethanol
Chlorphenesin
Sodium Benzoate
Water, Neopentyl Glycol Diheptanoate, Cetyl Alcohol, Butylene Glycol, Glycerin, Glyceryl Stearate, PEG-100 Stearate, Ammonium Acryloyldimethyltaurate/Vp Copolymer, Ascorbyl Glucoside, Potassium Cetyl Phosphate, Sodium Ascorbyl Phosphate, Bis-Diglyceryl Polyacyladipate-2, Polyglyceryl-10 Dioleate, Tetrahexyldecyl Ascorbate, Ceramide Ns, Ceramide EOP, Ceramide AP, Ceramide Eos, Ceramide NP, Palmitoyl Tripeptide-5, Acetyl Tetrapeptide-5, Caprooyl Phytosphingosine, Caprooyl Sphingosine, Cholesterol, Squalane, Retinol, Vitis Vinifera Seed Extract, Glycyrrhiza Glabra Root Extract, Punica Granatum Fruit Extract, Dunaliella Salina Extract, Pongamia Glabra Seed Oil, Tocopheryl Acetate, Allantoin, Bisabolol, Carnosine, Panthenol, Sodium PCA, Pullulan, Glyceryl Ascorbate, Behenic Acid, Dimethicone, Sodium Citrate, Sodium Polyacrylate, Caprylyl Glycol, Ethylhexyl Stearate, Ceteareth-25, Sodium Hydroxide, Trideceth-6, Propyl Gallate, Polysorbate 20, Disodium EDTA, Mica, Phenoxyethanol, Chlorphenesin, Sodium Benzoate
Dicaprylyl Carbonate
Triheptanoin
3-O-Ethyl Ascorbic Acid
Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer
Arachidyl Alcohol
Cetearyl Alcohol
C13-15 Alkane
Ascorbyl Palmitate
Sh-Polypeptide-121
Acetyl Hexapeptide-8
Hyaluronic Acid
Zerumbone
Bacillus Ferment
Tocopherol
Butyrospermum Parkii Butter Unsaponifiables
Oryza Sativa Bran Extract
Rosmarinus Officinalis Leaf Extract
Helianthus Annuus Seed Oil
Helianthus Annuus Seed Extract
Hydrogenated Lecithin
Cetearyl Olivate
Sorbitan Olivate
Behenyl Alcohol
Arachidyl Glucoside
Propanediol
Sodium Phytate
Citric Acid
Sodium Metabisulfite
Ethylhexylglycerin
Hexylene Glycol
Water, Dicaprylyl Carbonate, Glycerin, Triheptanoin, Ascorbyl Glucoside, 3-O-Ethyl Ascorbic Acid, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Arachidyl Alcohol, Cetearyl Alcohol, C13-15 Alkane, Ascorbyl Palmitate, Sh-Polypeptide-121, Acetyl Hexapeptide-8, Hyaluronic Acid, Zerumbone, Bacillus Ferment, Tocopherol, Tocopheryl Acetate, Butyrospermum Parkii Butter Unsaponifiables, Oryza Sativa Bran Extract, Rosmarinus Officinalis Leaf Extract, Helianthus Annuus Seed Oil, Helianthus Annuus Seed Extract, Hydrogenated Lecithin, Cetearyl Olivate, Sorbitan Olivate, Behenyl Alcohol, Arachidyl Glucoside, Propanediol, Butylene Glycol, Cetyl Alcohol, Sodium Phytate, Sodium Citrate, Citric Acid, Sodium Metabisulfite, Phenoxyethanol, Caprylyl Glycol, Ethylhexylglycerin, Hexylene Glycol, Sodium Hydroxide
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Alternatives
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Ascorbyl Glucoside (AA-2G) is one of the most stable vitamin C derivatives out there.
It's made by attaching a glucose molecule to ascorbic acid; this glucose "cap" shields the vitamin C from air, light, heat, and metal ions that normally cause pure ascorbic acid to oxidize.
Once on your skin, the enzyme alpha-glucosidase snips off the glucose and gradually releases active ascorbic acid right where it's needed. Basically, it behaves like a slow-release pro-vitamin C with less of a stinging that high-strength ascorbic acid can cause.
The research supports the classic vitamin C benefits as well. In lab and human studies, AA-2G slowed down the skin's production of melanin (the pigment behind dark spots) and helped shield skin cells against sun damage better than ascorbyl phosphate.
These studies also showed AA-2G released vitamin C over a longer period.
A frequently cited manufacturer trial found that a 2% AA-2G face cream significantly improved wrinkle depth and skin roughness after 45 days.
And in 2009, a clinical trial showed it meaningfully lightened dark patches on the gums compared to a placebo.
There's also collagen-synthesis support (since vitamin C is a required cofactor for that) and an antioxidant effect too.
Typical usage is usually between 0.5-5% and most studies/products land around 2%.
AA-2G performs best when formulated at a mildly acidic pH (~5-7) which is much gentler than the pH that pure vitamin C demands (~2.5-3.5).
Just one thing worth knowing: the in-skin conversation rate is only about 55-60% by weight. So a 5% AA-2G product delivers roughly 2.75-3% of actual active vitamin C. On top of that, skin absorption is relatively low because the ingredient is water-soluble.
Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:
Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.
Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.
Caprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created.
Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin.
Because it is not a free-fatty acid, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on).
Cetyl Alcohol is a fatty alcohol. Fatty Alcohols are most often used as an emollient or to thicken a product.
Its main roles are:
Though it has "alcohol" in the name, it is not related to denatured alcohol or ethyl alcohol.
The FDA allows products labeled "alcohol-free" to have fatty alcohols.
This ingredient may not be fungal acne safe. It is a primary fatty alcohol with a chain length above 12 carbons. A study from 2019 show Malassezia can feed on fatty alcohols in this range, so it may trigger fungal acne in those prone to it.
Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).
It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.
On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.
Another perk of this ingredient is that it stays functional across a wide pH range (3-10).
You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.
Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.
Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.
Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.
Sodium Citrate is the sodium salts of citric acid. In skincare, it is used to alter pH levels and acts as a preservative.
Its main functions are to maintain the pH of a product and neutralize metal ions.
The acidity of our skin is maintained by our glands and skin biome; normal pH level of skin is slightly acidic (~4.75-5.5).
Being slightly acidic allows our skin to create an "acid mantle". This acid mantle is a thin barrier that protects our skin from bacteria and contaminants.
Sodium Hydroxide is also known as lye or caustic soda. It is used to adjust the pH of products; many ingredients require a specific pH to be effective.
In small amounts, sodium hydroxide is considered safe to use. However, large amounts may cause chemical burns due to its high alkaline.
Your skin has a natural pH and acid mantle. This acid mantle helps prevent harmful bacteria from breaking through. The acid mantle also helps keep your skin hydrated.
"Alkaline" refers to a high pH level. A low pH level would be considered acidic.
Tocopheryl Acetate is a stable, shelf-friendly form of vitamin E.
Formulators love it because plain vitamin E oxidizes quickly once it hits air. This acetate version stays stable and resists going off, helping to extend a product's shelf life.
It's actually inactive on its own and works like a slow-release "storage" form; the enzymes in your skin called esterases gradually convert it into active vitamin E over time.
One in vivo study showed 5% of the acetate in the living layer of the epidermis converted to vitamin E after 5 days of application. This study also found the skin gained protection against UV damage even though the conversion was slow and small.
Once converted, vitamin E acts as a skin's main fat-soluble antioxidant that fights free radicals to protect skin from damage.
Topical vitamin E generally boosts the skin's photoprotection, and it reduced UV-damage in animal models.
This ingredient has some brightening potential but it's more of a prevention ingredient than spot-fader. Cell studies show it can slow down melanin production but it's worth noting that it's not the most powerful brightener out there.
Overall, it has a pretty solid safety profile and has been found to be non-irritating and non-comedogenic. Allergic reactions may happen but stay rare due to how widely the ingredient gets used.
The concentration will vary depending on the formula; industry data shows 0.1% in baby lotions, 3% in lipsticks, and 5% in foot powders. You can also find this ingredient at 100% in a pure vitamin E oil.
Most leave-on skincare keeps it at the lower end, often between 0.5-1%.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!