Peptide Skincare & BeautySkin science and ingredient guides

Skin science article

Paula's Choice Resist Advanced Replenishing Toner Versus The Ordinary Natural Moisturizing Factors + Beta Glucan

Paula's Choice Resist Advanced Replenishing Toner Versus The Ordinary Natural Moisturizing Factors + Beta Glucan This barrier-repair toner is formulated around Linoleic Acid and Phospholipids to strengthen the skin barrier and hydrate skin. This barrier-repair

Paula's Choice Resist Advanced Replenishing Toner Versus The Ordinary Natural Moisturizing Factors + Beta Glucan

This barrier-repair toner is formulated around Linoleic Acid and Phospholipids to strengthen the skin barrier and hydrate skin.

This barrier-repair moisturizer is formulated around Beta-Glucan to strengthen the skin barrier and hydrate skin.

What's inside

Key Ingredients

Benefits

Concerns

No concerns

Ingredients Side-by-side

Water

Cyclopentasiloxane

Glycerin

Glycereth-26

Polysorbate 20

Dimethiconol

Linoleic Acid

Oleic Acid

Linolenic Acid

Phospholipids

Carnosine

Epigallocatechin Gallate

Genistein

Sodium Hyaluronate

Sphingolipids

Ferulic Acid

Laurdimonium Hydroxypropyl Hydrolyzed Soy Protein

Glycyrrhiza Glabra Root Extract

Acetyl Glucosamine

Quercetin

Oenothera Biennis Oil

Beta Vulgaris Root Extract

Cucurbita Pepo Seed Extract

Lecithin

Caprylic/Capric Triglyceride

Hydrolyzed Corn Starch

Hydrogenated Lecithin

Palmitic Acid

Butylene Glycol

Acrylates/C10-30 Alkyl Acrylate Crosspolymer

Xanthan Gum

Laureth-23

Laureth-4

Aminomethyl Propanol

Disodium EDTA

Sodium Benzoate

Ethylhexylglycerin

Phenoxyethanol

Chlorphenesin

Benzoic Acid

Sorbic Acid

Water, Cyclopentasiloxane, Glycerin, Glycereth-26, Polysorbate 20, Dimethiconol, Linoleic Acid, Oleic Acid, Linolenic Acid, Phospholipids, Carnosine, Epigallocatechin Gallate, Genistein, Sodium Hyaluronate, Sphingolipids, Ferulic Acid, Laurdimonium Hydroxypropyl Hydrolyzed Soy Protein, Glycyrrhiza Glabra Root Extract, Acetyl Glucosamine, Quercetin, Oenothera Biennis Oil, Beta Vulgaris Root Extract, Cucurbita Pepo Seed Extract, Lecithin, Caprylic/Capric Triglyceride, Hydrolyzed Corn Starch, Hydrogenated Lecithin, Palmitic Acid, Butylene Glycol, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Xanthan Gum, Laureth-23, Laureth-4, Aminomethyl Propanol, Disodium EDTA, Sodium Benzoate, Ethylhexylglycerin, Phenoxyethanol, Chlorphenesin, Benzoic Acid, Sorbic Acid

PPG-24-Glycereth-24

Propanediol

Betaine

Beta-Glucan

Arginine

Glycine

Alanine

Serine

Proline

Threonine

Glutamic Acid

Lysine Hcl

Glucose

Maltose

Fructose

Trehalose

Xylitol

Anhydroxylitol

Xylitylglucoside

Sodium PCA

PCA

Sodium Lactate

Urea

Allantoin

Pentylene Glycol

Sodium Hydroxide

Sodium Chloride

Sodium Citrate

Citric Acid

Tocopherol

P-Anisic Acid

Water, PPG-24-Glycereth-24, Propanediol, Betaine, Beta-Glucan, Arginine, Glycine, Alanine, Serine, Proline, Threonine, Glutamic Acid, Lysine Hcl, Glucose, Maltose, Fructose, Trehalose, Xylitol, Anhydroxylitol, Xylitylglucoside, Sodium PCA, PCA, Sodium Lactate, Urea, Allantoin, Sodium Hyaluronate, Phospholipids, Sphingolipids, Glycerin, Pentylene Glycol, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Sodium Hydroxide, Sodium Chloride, Sodium Citrate, Citric Acid, Tocopherol, P-Anisic Acid, Aminomethyl Propanol, Phenoxyethanol, Chlorphenesin

Reviews

Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Acrylates/C10-30 Alkyl Acrylate Crosspolymer is a synthetic polymer. It is used to thicken, emulsify, and improve the texture of products.

As an emulsifier, it helps stabilize oil-in-water emulsions to give products an elegant feel when applied.

It can also form a thin protective film on skin. One study found that a formula using this polymer helped slow down how quickly other ingredients (like DEET) were absorbed through skin.

A 2024 study of over 1,300 patients confirmed that sensitization to this ingredient is rare. It is also non-mutagenic and has a clean track record.

Aminomethyl Propanol is used to adjust the pH of products. It is also used as a base to create other organic compounds. Having a balanced pH is important for protecting your skin.

Aminomethyl propanol is safe to use in cosmetics up to 1%. It is soluble in water.

Chlorphenesin is a synthetic preservative. It helps protect a product against bacteria in order to extend shelf life. In most cases, Chlorphenesin is paired with other preservatives such as phenoxyethanol and caprylyl glycol.

Chlorphenesin is a biocide. This means it is able to help fight the microorganisms on our skin. It is also able to fight odor-releasing bacteria.

Chlorphenesin is soluble in both water and glycerin.

Studies show Chlorphenesin is easily absorbed by our skin. You should speak with a skincare professional if you have concerns about using Chlorphenesin.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).

It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.

On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.

Another perk of this ingredient is that it stays functional across a wide pH range (3-10).

You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.

Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.

Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.

Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.

Phospholipids are a family of skin-identical lipids that makeup the structural backbone of every cell membrane in your body.

In cosmetics, they function as skin conditioning agents with emulsifier and surfactant properties. They're typically sourced from soybean or sunflower lecithin (or sometimes egg yolk or marine sources).

Because they mirror the lipids naturally found in the deeper layers of your skin, topical phospholipids help reinforce the lipid matrix, reduce transepidermal water loss, and leave skin feeling conditioned.

They're also used to form liposomes, or tiny self-assembling vesible used to stabilize actives like vitamin c or retinol. This helps these ingredients integrate into the upper layers of skin more easily.

Phospholipids are compatible with everything and the CIR Expert Panel has concluded them to be safe at current use levels.

Some types of phospholipids include:

Sodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity.

In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface.

Interestingly, the size of the molecule affects its behavior:

Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.

Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.

You'll typically see concentrations between 0.1-2% for this ingredient.

Sphingolipids are a major class of lipids in cell membranes. This ingredient has emollient, skin conditioning, and skin protecting properties.

Certain ceramides are considered sphingolipids (Ceramide NS and Ceramid AP), but not all sphingolipids are ceramides.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

Similar Comparisons

The reference edit

Ingredients, questions
& further reading.

Connected source records selected through this article’s public topic index.

01

Formula cabinet

Ingredients & structured notes

Ingredient index

Ingredients Side-by-side

  1. 01Water
  2. 02Cyclopentasiloxane
  3. 03Octyldodecyl Neopentanoate
  4. 04Vinyl Dimethicone/Methicone Silsesquioxane Crosspolymer
  5. 05Glycerin
  6. 06Sodium Ascorbyl Phosphate
  7. 07Cetyl Alcohol
  8. 08Niacinamide
  9. 09Dimethicone
  10. 10Cetearyl Alcohol
  11. 11Butylene Glycol
  12. 12Glyceryl Stearate
  13. 13PEG-100 Stearate
  14. 14Adenosine
  15. 15Epigallocatechin Gallate
  16. 16Glucose Oxidase
  17. 17Lactoperoxidase
  18. 18Boerhavia Diffusa Root Extract
  19. 19Cocos Nucifera Fruit Extract
  20. 20Lactobacillus
Source · skinsort.com
02

Product index

Related product references

Product

Paula's Choice Shine Stopper

Paula's Choice Shine Stopper Paula's Choice Shine Stopper ingredients explained: Aqua, Methyl Methacrylate/Glycol Dimethacrylate Crosspolymer (Film-Forming Agent/Absorbent Polymer), Capryli…

Source: incidecoder.comView reference →
03

Comparison edit

Read side by side