ReVive Skincare Fermitif™ Neck Renewal Serum Firming Treatment Versus Educated Mess Freeze Frame Peptide Serum Concentrate

ReVive Skincare Fermitif™ Neck Renewal Serum Firming Treatment Versus Educated Mess Freeze Frame Peptide Serum Concentrate

This anti-aging treatment is formulated around Niacinamide and 3-O-Ethyl Ascorbic Acid to soften the look of wrinkles and refine skin texture.

This anti-aging serum is formulated around Resveratrol and Palmitoyl Pentapeptide-4 to soften the look of wrinkles and refine skin texture.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Glycerin

Niacinamide

Biosaccharide Gum-4

Cocoglycerides

Propanediol

Isododecane

Pentylene Glycol

Dimethicone

3-O-Ethyl Ascorbic Acid

Oligopeptide-20

Acetyl Hexapeptide-8

Oligopeptide-24

Pentapeptide-4

Heptapeptide-15 Palmitate

D-Arginyl Tyrosinyl Ornithinyl Phenylalanine

Copper Heptapeptide-14 Pantothenate

Caesalpinia Spinosa Fruit Extract

Tocopherol

Glycyrrhiza Glabra Root Extract

Camellia Sinensis Leaf Extract

Avena Sativa Kernel Oil

Allantoin

Kappaphycus Alvarezii Extract

Tocopheryl Acetate

Algin

Pichia Ferment Lysate Filtrate

Alpha-Glucan Oligosaccharide

Pullulan

Hydrolyzed Jojoba Esters

Sodium Oleate

Glycine Soja Oil

Hydrogenated Lecithin

Parfum

Lactic Acid/Glycolic Acid Copolymer

Hydrogenated Phosphatidylcholine

Ubiquinone

Dextran

Acrylates/Dimethicone Copolymer

Ethylhexylglycerin

Acrylates/C10-30 Alkyl Acrylate Crosspolymer

Maltodextrin

Phenoxyethanol

Potassium Hydroxide

Sodium Stearoyl Glutamate

Sodium Phytate

Disodium EDTA

Potassium Sorbate

Polyvinyl Alcohol

Water, Glycerin, Niacinamide, Biosaccharide Gum-4, Cocoglycerides, Propanediol, Isododecane, Pentylene Glycol, Dimethicone, 3-O-Ethyl Ascorbic Acid, Oligopeptide-20, Acetyl Hexapeptide-8, Oligopeptide-24, Pentapeptide-4, Heptapeptide-15 Palmitate, D-Arginyl Tyrosinyl Ornithinyl Phenylalanine, Copper Heptapeptide-14 Pantothenate, Caesalpinia Spinosa Fruit Extract, Tocopherol, Glycyrrhiza Glabra Root Extract, Camellia Sinensis Leaf Extract, Avena Sativa Kernel Oil, Allantoin, Kappaphycus Alvarezii Extract, Tocopheryl Acetate, Algin, Pichia Ferment Lysate Filtrate, Alpha-Glucan Oligosaccharide, Pullulan, Hydrolyzed Jojoba Esters, Sodium Oleate, Glycine Soja Oil, Hydrogenated Lecithin, Parfum, Lactic Acid/Glycolic Acid Copolymer, Hydrogenated Phosphatidylcholine, Ubiquinone, Dextran, Acrylates/Dimethicone Copolymer, Ethylhexylglycerin, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Maltodextrin, Phenoxyethanol, Potassium Hydroxide, Sodium Stearoyl Glutamate, Sodium Phytate, Disodium EDTA, Potassium Sorbate, Polyvinyl Alcohol

Acetamidoethoxyethanol

Propylene Glycol

Sodium Acrylates Crosspolymer-2

Cyclopentasiloxane

Polysorbate 20

1,2-Hexanediol

Menthyl Lactate

Resveratrol

Palmitoyl Pentapeptide-4

Palmitoyl Tetrapeptide-50

Palmitoyl Hexapeptide-52

Palmitoyl Heptapeptide-18

Diamond Powder

Methylglucoside Phosphate

Copper Lysinate/Prolinate

Sodium Hyaluronate

Xanthan Gum

Dimethicone Crosspolymer

Polyacrylate Crosspolymer-6

Hydroxyacetophenone

Glyceryl Caprylate

Phenylpropanol

Caprylyl Glycol

Water, Glycerin, Acetamidoethoxyethanol, Propylene Glycol, Sodium Acrylates Crosspolymer-2, Cyclopentasiloxane, Polysorbate 20, 1,2-Hexanediol, Menthyl Lactate, Resveratrol, Palmitoyl Pentapeptide-4, Palmitoyl Tetrapeptide-50, Heptapeptide-15 Palmitate, Palmitoyl Hexapeptide-52, Palmitoyl Heptapeptide-18, Diamond Powder, Methylglucoside Phosphate, Copper Lysinate/Prolinate, Sodium Hyaluronate, Lactic Acid/Glycolic Acid Copolymer, Polyvinyl Alcohol, Xanthan Gum, Dimethicone Crosspolymer, Dimethicone, Polyacrylate Crosspolymer-6, Hydroxyacetophenone, Glyceryl Caprylate, Phenylpropanol, Phenoxyethanol, Caprylyl Glycol

Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Dimethicone is a type of synthetic silicone created from natural materials such as quartz. It is also known as polydimethylsiloxane.

What it does:

Dimethicone comes in different viscosities:

Depending on the viscosity, dimethicone has different properties.

Ingredients lists don't always show which type is used, so we recommend reaching out to the brand if you have questions about the viscosity.

This ingredient is unlikely to cause irritation because it does not get absorbed into skin. However, people with silicone allergies should be careful about using this ingredient.

Note: Dimethicone may contribute to pilling. This is because it is not oil or water soluble, so pilling may occur when layered with products. When mixed with heavy oils in a formula, the outcome is also quite greasy.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Heptapeptide-15 Palmitate is a synthetic targeting peptide. It's made up of seven amino acids with a palmitic acid tail attached.

This fatty acid attachment increases the molecule's hydrophobicity, improves stability, reduces enzyme degradation, and enhances its ability to cross the skin's lipid barrier (this is a common challenge for peptides).

As a targeting peptide, it sits on the outer shell of an encapsulated ingredient system and seeks out receptors on collagen and elastin producing cells in skin.

Once it binds, the cell internalizes the capsule and releases the active payload inside; it essentially acts as a GPS guiding ingredients to the right place.

It also mimicks the skin's natural growth factors to support skin firmness by upping production of collagen, elastin, glycosaminoglycans (GAGs).

Most of the evidence for this ingredient comes from manufacturer in vitro data, so independent clinical trials are still limited. However, the underlying mechanism is well-supported by the broader cosmetic peptide literature.

Fungal acne note: Usually a palmitic acid component can feed Malassezia in unbound form, but here is is covalently bonded to the peptide. This means it is very difficult for Malassezia to access, and therefore very unlikely to cause fungal acne.

This ingredient is a combination of two AHAs, lactic acid and glycolic acid. It has exfoliating properties

Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).

It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.

On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.

Another perk of this ingredient is that it stays functional across a wide pH range (3-10).

You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.

Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.

Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.

Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.

We don't have a description for Polyvinyl Alcohol yet.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

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