Skinfix Barrier+ Triple Lipid + Collagen + Niacinamide Activating Serum Versus Naturium Multi-Peptide Advanced Serum

Skinfix Barrier+ Triple Lipid + Collagen + Niacinamide Activating Serum Versus Naturium Multi-Peptide Advanced Serum

This barrier-repair serum is formulated around Niacinamide and Ceramide NP to strengthen the skin barrier and soften the look of wrinkles.

This anti-aging serum is formulated around Acetyl Hexapeptide-8 and Ferulic Acid to soften the look of wrinkles.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Caprylyl Caprylate/Caprate

Propanediol

Jojoba Oil/Macadamia Seed Oil Esters

Niacinamide

Glycerin

Ammonium Acryloyldimethyltaurate/Vp Copolymer

Squalene

Macadamia Integrifolia Seed Oil

Amylopectin

Lecithin

Phytosteryl Macadamiate

Collagen Amino Acids

Lithothamnion Calcareum Extract

Sodium Hyaluronate

Oligopeptide-3

Oligopeptide-2

Oligopeptide-1

Hexapeptide-11

Folic Acid

Bacillus/Soybean Ferment Extract

Lactic Acid

Phospholipids

Ceramide NP

Phytosterols

Phytosphingosine

Ceramide AP

Cholesterol

Myrica Cerifera Fruit Extract

Akebia Quinata Stem Extract

Prunus Lannesiana Flower Extract

Saccharomyces Lysate

Lactobacillus Ferment Lysate

Tripeptide-1

Ceramide EOP

Polyglutamic Acid

Tocopheryl Acetate

Tocopherol

Butylene Glycol

Caprylyl Glycol

Sodium Lauroyl Lactylate

Ethylhexylglycerin

Hexylene Glycol

Pentylene Glycol

Acetyl Glutamine

Trisodium Ethylenediamine Disuccinate

Leuconostoc/Radish Root Ferment Filtrate

Sodium Benzoate

Hydroxyacetophenone

Xanthan Gum

Potassium Sorbate

Carbomer

1,2-Hexanediol

Dextran

Phenoxyethanol

Water, Caprylyl Caprylate/Caprate, Propanediol, Jojoba Oil/Macadamia Seed Oil Esters, Niacinamide, Glycerin, Ammonium Acryloyldimethyltaurate/Vp Copolymer, Squalene, Macadamia Integrifolia Seed Oil, Amylopectin, Lecithin, Phytosteryl Macadamiate, Collagen Amino Acids, Lithothamnion Calcareum Extract, Sodium Hyaluronate, Oligopeptide-3, Oligopeptide-2, Oligopeptide-1, Hexapeptide-11, Folic Acid, Bacillus/Soybean Ferment Extract, Lactic Acid, Phospholipids, Ceramide NP, Phytosterols, Phytosphingosine, Ceramide AP, Cholesterol, Myrica Cerifera Fruit Extract, Akebia Quinata Stem Extract, Prunus Lannesiana Flower Extract, Saccharomyces Lysate, Lactobacillus Ferment Lysate, Tripeptide-1, Ceramide EOP, Polyglutamic Acid, Tocopheryl Acetate, Tocopherol, Butylene Glycol, Caprylyl Glycol, Sodium Lauroyl Lactylate, Ethylhexylglycerin, Hexylene Glycol, Pentylene Glycol, Acetyl Glutamine, Trisodium Ethylenediamine Disuccinate, Leuconostoc/Radish Root Ferment Filtrate, Sodium Benzoate, Hydroxyacetophenone, Xanthan Gum, Potassium Sorbate, Carbomer, 1,2-Hexanediol, Dextran, Phenoxyethanol

Caprylic/Capric Triglyceride

Isopentyldiol

Ethylhexyl Polyhydroxystearate

Squalane

Tetradecane

Glyceryl Stearate Citrate

Butyrospermum Parkii Butter

Polyglyceryl-3 Stearate

Helianthus Annuus Extract

Oryza Sativa Bran Extract

Mannitol

Phosphatidylcholine

Ferulic Acid

Arginine

Acetyl Hexapeptide-8

Copper Palmitoyl Heptapeptide-14

Palmitoyl Sh-Heptapeptide-12 Sp

Hydrolyzed Collagen

Rosmarinus Officinalis Leaf Extract

Lactic Acid/Glycolic Acid Copolymer

Pullulan

Lysolecithin

Sclerotium Gum

Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer

Dimethicone

Sodium Phytate

Diglycerin

Hydrogenated Lecithin

Silica

Cetyl Alcohol

Polysorbate 60

Sorbitan Isostearate

Sodium Hydroxide

Polyvinyl Alcohol

Decyl Glucoside

Sodium Chloride

Citric Acid

Water, Propanediol, Caprylic/Capric Triglyceride, Isopentyldiol, Ethylhexyl Polyhydroxystearate, Squalane, Tetradecane, Glyceryl Stearate Citrate, Butyrospermum Parkii Butter, Polyglyceryl-3 Stearate, Helianthus Annuus Extract, Oryza Sativa Bran Extract, Mannitol, Phosphatidylcholine, Ferulic Acid, Arginine, Acetyl Hexapeptide-8, Copper Palmitoyl Heptapeptide-14, Palmitoyl Sh-Heptapeptide-12 Sp, Hydrolyzed Collagen, Rosmarinus Officinalis Leaf Extract, Lactic Acid/Glycolic Acid Copolymer, Glycerin, Tocopherol, Pullulan, Lysolecithin, Sclerotium Gum, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Dimethicone, Sodium Phytate, Diglycerin, Hydrogenated Lecithin, Silica, Cetyl Alcohol, Hydroxyacetophenone, Polysorbate 60, Sorbitan Isostearate, Sodium Hydroxide, Sodium Benzoate, Potassium Sorbate, Polyvinyl Alcohol, Decyl Glucoside, Xanthan Gum, Tocopheryl Acetate, Sodium Chloride, Citric Acid, Phenoxyethanol

Reviews

Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Hydroxyacetophenone is a small phenolic molecule that earns its place in a formulas as an antioxidant and preservative booster.

As a phenol, it is able to neutralize free radicals to protect both the product and the skin from oxidative stress.

Though it can't kill microbes on its own, it works as a good supporting agent when combined with other preservatives like Phenoxyethanol or 1,2-Hexanediol.

This ingredient naturally occurs as piceol in Norwegian spruce needles (~0.4-1.1% dry weight and in cloudberries). Though the cosmetic-grade material is synthesized for purity and consistency.

You'll usually see it used at low levels and suppliers recommend up to 1% added to a water phase.

Safety testing was done at concentrations like 0.05% in SPF products and 0.5% in a Human Repeated Insult Patch Test. The safety evidence is assuring; this ingredient is safe for cosmetics in current use and also holds safety status as a food flavoring as well.

An honest caveat: the "soothing" and "anti-inflammatory" claims come mostly from supplier marketing rather than published clinical trials. The Cosmetic Ingredient Review's own literature search found no useful efficacy studies on this ingredient.

So the antioxidant and preservative-boosting roles are the well supported ones while the calming benefit is plausible but thinly evidenced.

Overall, this is a well-tolerated, low-irritation multitasker that quietly helps a formula stay fresh and stable.

Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).

It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.

On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.

Another perk of this ingredient is that it stays functional across a wide pH range (3-10).

You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.

Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.

Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.

Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.

Potassium Sorbate is a preservative used to prevent yeast and mold in products. It is commonly found in both cosmetic and food products.

This ingredient comes from potassium salt derived from sorbic acid. Sorbic acid is a natural antibiotic and effective against fungus.

Both potassium sorbate and sorbic acid can be found in baked goods, cheeses, dried meats, dried fruit, ice cream, pickles, wine, yogurt, and more.

You'll often find this ingredient used with other preservatives.

Propanediol is an all-star ingredient. It softens, hydrates, and smooths the skin.

It’s often used to:

Propanediol is not likely to cause sensitivity and considered safe to use. It is derived from corn or petroleum with a clear color and no scent.

Sodium Benzoate is a preservative. It's used in both cosmetic and food products to inhibit the growth of mold and bacteria. It is typically produced synthetically.

Both the US FDA and EU Health Committee have approved the use of sodium benzoate. In the US, levels of 0.1% (of the total product) are allowed.

Sodium benzoate works as a preservative by inhibiting the growth of bacteria inside of cells. It prevents the cell from fermenting a type of sugar using an enzyme called phosphofructokinase.

It is the salt of benzoic acid. Foods containing sodium benzoate include soda, salad dressings, condiments, fruit juices, wines, and snack foods.

Studies for using ascorbic acid and sodium benzoate in cosmetics are lacking, especially in skincare routines with multiple steps.

We always recommend speaking with a professional, such as a dermatologist, if you have any concerns.

Tocopherol is a fat-soluble antioxidant known as Vitamin E.

You'll find this ingredient in the vast majority of skincare (for good reason). It works to neutralize free radicals, or unstable molecules generated by UV exposure, pollution, and other environmental stressors, before they can cause oxidative damage to your skin cells.

Topically applied tocopherol has been shown to protect against UV damage by ramping up the skin's own natural defense enzymes.

It also acts as a skin conditioning agent; some studies show that regular topical use can improve the skin's water-binding capacity over 2-4 weeks.

This ingredient is especially loved for being a team player. When combined with Vitamin C, the photoprotective effect of both ingredients roughly doubles and the combo also helps reduce UV-induced DNA damage.

This ingredient has some brightening potential but it's more of a prevention ingredient than spot-fader. Cell studies show it can slow down melanin production but it's worth noting that it's not the most powerful brightener out there.

In formulations, it also serves as a stabilizer that helps protect other oxidation-prone ingredients from degrading.

Concentrations usually range from 0.1-1% in most leave-on products.

Tocopheryl Acetate is a stable, shelf-friendly form of vitamin E.

Formulators love it because plain vitamin E oxidizes quickly once it hits air. This acetate version stays stable and resists going off, helping to extend a product's shelf life.

It's actually inactive on its own and works like a slow-release "storage" form; the enzymes in your skin called esterases gradually convert it into active vitamin E over time.

One in vivo study showed 5% of the acetate in the living layer of the epidermis converted to vitamin E after 5 days of application. This study also found the skin gained protection against UV damage even though the conversion was slow and small.

Once converted, vitamin E acts as a skin's main fat-soluble antioxidant that fights free radicals to protect skin from damage.

Topical vitamin E generally boosts the skin's photoprotection, and it reduced UV-damage in animal models.

Overall, it has a pretty solid safety profile and has been found to be non-irritating and non-comedogenic. Allergic reactions may happen but stay rare due to how widely the ingredient gets used.

The concentration will vary depending on the formula; industry data shows 0.1% in baby lotions, 3% in lipsticks, and 5% in foot powders. You can also find this ingredient at 100% in a pure vitamin E oil.

Most leave-on skincare keeps it at the lower end, often between 0.5-1%.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.

On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.

Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.

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