Peptide Skincare & BeautySkin science and ingredient guides

Skin science article

Slurp Hyaluid Versus Naturium Multi-Peptide Advanced Serum

Slurp Hyaluid Versus Naturium Multi-Peptide Advanced Serum This hydrating serum is formulated around Sodium Hyaluronate and Niacinamide to hydrate skin and strengthen the skin barrier. This anti-aging serum is formulated around Acetyl Hexapeptide-8 and Ferulic

Slurp Hyaluid Versus Naturium Multi-Peptide Advanced Serum

This hydrating serum is formulated around Sodium Hyaluronate and Niacinamide to hydrate skin and strengthen the skin barrier.

This anti-aging serum is formulated around Acetyl Hexapeptide-8 and Ferulic Acid to soften the look of wrinkles.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Erythritol

1,2-Hexanediol

Propanediol

Sodium Hyaluronate

Caesalpinia Spinosa Fruit Extract

Chlorphenesin

Niacinamide

Betaine

Allantoin

Kappaphycus Alvarezii Extract

Hydrolyzed Collagen

Asiaticoside

Glycerin

Adenosine

Xylitylglucoside

Ethylhexylglycerin

Anhydroxylitol

Butylene Glycol

Dextrin

Xylitol

3-O-Ethyl Ascorbic Acid

Panthenol

Hydrolyzed Elastin

Glucose

Pentylene Glycol

Cynanchum Atratum Extract

Sodium Chloride

Madecassoside

Sodium Deoxycholate

Disodium Phosphate

Sodium Phosphate

Hydroxypropyltrimonium Hyaluronate

Sr-(Oligopeptide-91 Clostridium Botulinum Polypeptide-1)

Polysorbate 20

Sodium Acetylated Hyaluronate

Hydrolyzed Hyaluronic Acid

Lecithin

Phosphatidylcholine

Acetyl Hexapeptide-8

Palmitoyl Tripeptide-1

Hyaluronic Acid

Sodium Hyaluronate Crosspolymer

Copper Tripeptide-1

Hydrolyzed Sodium Hyaluronate

Potassium Hyaluronate

Sh-Oligopeptide-2

Sh-Polypeptide-1

Sh-Polypeptide-2

Erythritol, 1,2-Hexanediol, Propanediol, Sodium Hyaluronate, Caesalpinia Spinosa Fruit Extract, Chlorphenesin, Niacinamide, Betaine, Allantoin, Kappaphycus Alvarezii Extract, Hydrolyzed Collagen, Asiaticoside, Glycerin, Adenosine, Xylitylglucoside, Ethylhexylglycerin, Anhydroxylitol, Butylene Glycol, Dextrin, Xylitol, 3-O-Ethyl Ascorbic Acid, Panthenol, Hydrolyzed Elastin, Glucose, Pentylene Glycol, Cynanchum Atratum Extract, Sodium Chloride, Madecassoside, Sodium Deoxycholate, Disodium Phosphate, Sodium Phosphate, Hydroxypropyltrimonium Hyaluronate, Sr-(Oligopeptide-91 Clostridium Botulinum Polypeptide-1), Polysorbate 20, Sodium Acetylated Hyaluronate, Hydrolyzed Hyaluronic Acid, Lecithin, Phosphatidylcholine, Acetyl Hexapeptide-8, Palmitoyl Tripeptide-1, Hyaluronic Acid, Sodium Hyaluronate Crosspolymer, Copper Tripeptide-1, Hydrolyzed Sodium Hyaluronate, Potassium Hyaluronate, Sh-Oligopeptide-2, Sh-Polypeptide-1, Sh-Polypeptide-2

Water

Caprylic/Capric Triglyceride

Isopentyldiol

Ethylhexyl Polyhydroxystearate

Squalane

Tetradecane

Glyceryl Stearate Citrate

Butyrospermum Parkii Butter

Polyglyceryl-3 Stearate

Helianthus Annuus Extract

Oryza Sativa Bran Extract

Mannitol

Ferulic Acid

Arginine

Copper Palmitoyl Heptapeptide-14

Palmitoyl Sh-Heptapeptide-12 Sp

Rosmarinus Officinalis Leaf Extract

Lactic Acid/Glycolic Acid Copolymer

Tocopherol

Pullulan

Lysolecithin

Sclerotium Gum

Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer

Dimethicone

Sodium Phytate

Diglycerin

Hydrogenated Lecithin

Silica

Cetyl Alcohol

Hydroxyacetophenone

Polysorbate 60

Sorbitan Isostearate

Sodium Hydroxide

Sodium Benzoate

Potassium Sorbate

Polyvinyl Alcohol

Decyl Glucoside

Xanthan Gum

Tocopheryl Acetate

Citric Acid

Phenoxyethanol

Water, Propanediol, Caprylic/Capric Triglyceride, Isopentyldiol, Ethylhexyl Polyhydroxystearate, Squalane, Tetradecane, Glyceryl Stearate Citrate, Butyrospermum Parkii Butter, Polyglyceryl-3 Stearate, Helianthus Annuus Extract, Oryza Sativa Bran Extract, Mannitol, Phosphatidylcholine, Ferulic Acid, Arginine, Acetyl Hexapeptide-8, Copper Palmitoyl Heptapeptide-14, Palmitoyl Sh-Heptapeptide-12 Sp, Hydrolyzed Collagen, Rosmarinus Officinalis Leaf Extract, Lactic Acid/Glycolic Acid Copolymer, Glycerin, Tocopherol, Pullulan, Lysolecithin, Sclerotium Gum, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Dimethicone, Sodium Phytate, Diglycerin, Hydrogenated Lecithin, Silica, Cetyl Alcohol, Hydroxyacetophenone, Polysorbate 60, Sorbitan Isostearate, Sodium Hydroxide, Sodium Benzoate, Potassium Sorbate, Polyvinyl Alcohol, Decyl Glucoside, Xanthan Gum, Tocopheryl Acetate, Sodium Chloride, Citric Acid, Phenoxyethanol

Reviews

Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Acetyl Hexapeptide-8 (also known as Argireline) is a synthetic hexapeptide that is often called a "topical Botox alternative".

It works by mimicking how Botox relaxes muscles; it interferes with the signaling process that tells your facial muscles to contract. This can help soften expression lines like forehead wrinkles or crow's feet over time.

The comparison to Botox does have limits because the molecule is water-loving and relatively large.

Acetyl Hexapeptide-8 has a hard time absorbing deeply enough through the skin's outer barrier to actually reach the muscles.

So whether it truly works the way Botox does at a biological level is still up for debate, but early clinical outcomes are fairly encouraging.

A 12 week human study of a multi-ingredient regimen containing this ingredient saw:

While some studies have observed improvements in wrinkle appearance, it is important to note that more consistent results are seen in multi-ingredient formulations (vs just Acetyl Hexapeptide-8 alone).

Some research studies also used higher concentrations (up to 10%) while this ingredient is usually found in concentrations up to 0.005% in leave-on formulations.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Hydrolyzed Collagen is Collagen (usually sourced from fish, bovine, or porcine byproducts) that's been broken down into smaller peptides. This makes it water-soluble and easy to blend into formulations.

In a formula, it works mainly as a skin-conditioning and moisturizing agent.

The small peptides and amino acids (including Natural Moisturizing Factor components like Hydroxyproline, Serine, and Aspartic Acid) help the surface of the skin hold onto water, feel softer, and look temporarily plumper.

This ingredient also has mild film-forming and antioxidant properties with research showing the antioxidant effect is stronger the lower the molecular weight of the peptides.

It's worth being realistic here:

Topically applied Hydrolyzed Collagen conditions the upper layers of skin rather than rebuilding the structural collagen deep in your dermis (the wrinkle-and-firmness benefits people associate with Collagen mostly come from oral supplements in studies, not topicals).

However, recent lab and skin-model work on Hydrolyzed Fish Collagen has shown promising effects on cell viability and wound healing when used as an active.

Typical concentrations range from 0.2-2%, but the percentage can go much higher in rinse-off or hair products (sometimes even above 50%).

Clinical studies on this ingredient showed no irritation, sensitization, or phototoxicity.

If you are looking for vegan collagen, it usually goes by a different INCI name like hydrolyzed soy protein. Vegan collagen is derived from yeast, bacteria, or plant sources.

The results are varied.

A study from 2021 found hydrolyzed collagen increased elasticity and improved wrinkles in 1,125 participants between age 20 and 70. Another study found increased skin thickness in participants between the ages of 45 to 59.

However, It is difficult to prove that oral collagen will end up working on your skin. Many of the studies using hydrolyzed collagen also add several vitamins and nutrients into the test mixture as well.

Further studies are needed at this time.

Phosphatidylcholine (PC) is a type of phospholipid, a class of molecule that makes up our own cell membranes.

It has a glycerol backbone, two fatty acid tails (mostly linoleic, palmitic, and oleic), and a phosphate-choline head group.

In skincare, PC pulls double duty:

The linoleic acid it carries gets incorporated into skin ceramides and helps reinforce the lipid matrix.

Interestingly, it can help top of the omega-6 fatty acid that's often low in acne-prone and atopic skin. There's a sizeable body of literature that supports its use in dry, barrier-impaired, and breakout-prone skin.

There are two kinds of PC you'll see on ingredient lists.

Use levels range from <1% as a liposomal carrier and between 20-40% in lamellar matrix sytems.

Propanediol is an all-star ingredient. It softens, hydrates, and smooths the skin.

It’s often used to:

Propanediol is not likely to cause sensitivity and considered safe to use. It is derived from corn or petroleum with a clear color and no scent.

Chances are, you eat sodium chloride every day. Sodium Chloride is also known as table salt. This ingredient has many purposes in skincare: thickener, emulsifier, and exfoliator.

You'll most likely find this ingredient in cleansers where it is used to create a gel-like texture. As an emulsifier, it also prevents ingredients from separating.

You might see people debate whether Sodium Chloride is comedogenic, but there actually haven't been any comedogenic tests done on it. Either way, the overall formulation of a product matters a lot more than any single ingredient.

You might see this ingredient used in scrubs as a primary exfoliating ingredient.

Similar Comparisons

The reference edit

Ingredients, questions
& further reading.

Connected source records selected through this article’s public topic index.

01

Formula cabinet

Ingredients & structured notes

Ingredient index

Ingredients Explained

  1. 01These ingredients are found in both products.
  2. 02Ingredients higher up in an ingredient list are typically present in a larger amount.
  3. 03Cetyl Alcohol is a fatty alcohol. Fatty Alcohols are most often used as an emollient or to thicken a product.
  4. 04Its main roles are:
  5. 05Though it has "alcohol" in the name, it is not related to denatured alcohol or ethyl alcohol.
  6. 06The FDA allows products labeled "alcohol-free" to have fatty alcohols.
  7. 07This ingredient may not be fungal acne safe. It is a primary fatty alcohol with a chain length above 12 carbons. A study from 2019 show Malassezia can feed on fatty alcohols in this range, so it may trigger fungal acne in those prone to it.
  8. 08Citric Acid is an alpha hydroxy acid (AHA) naturally found in citrus fruits like oranges, lemons, and limes.
  9. 09Like other AHAs, citric acid can exfoliate skin by breaking down the bonds that hold dead skin cells together. This helps reveal smoother and brighter skin underneath.
  10. 10However, this exfoliating effect only happens at high concentrations (20%) which can be hard to find in cosmetic products.
  11. 11Due to this, citric acid is usually included in small amounts as a pH adjuster. This helps keep products slightly more acidic and compatible with skin's natural pH.
  12. 12In skincare formulas, citric acid can:
  13. 13While it can provide some skin benefits, research shows lactic acid and glycolic acid are generally more effective and less irritating exfoliants.
  14. 14Most citric acid used in skincare today is made by fermenting sugars (usually from molasses). This synthetic version is identical to the natural citrus form but easier to stabilize and use in formulations.
  15. 15Rosacea skin has a lower threshold for acids generally, with 62.5% of rosacea subjects in one study reacting to lactic acid in a sting test. This is why we mark citric acid as a potential rosacea trigger.
  16. 16However, this ingredient shows up as a pH adjuster or chelator at roughly 0.1-1% in many products. These low levels are unlikely to be an issue for rosacea skin and becomes a potential trigger at exfoliating concentrations (20%). Because everybody's…
  17. 17Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
  18. 18Topically, glycerin does several things at once:
  19. 19Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
  20. 20Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
Source · skinsort.com
02

Product index

Related product references

Product

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Source: incidecoder.comView reference →
03

Comparison edit

Read side by side