Skin science article
Slurp Hyaluid Versus Naturium Multi-Peptide Advanced Serum
Slurp Hyaluid Versus Naturium Multi-Peptide Advanced Serum This hydrating serum is formulated around Sodium Hyaluronate and Niacinamide to hydrate skin and strengthen the skin barrier. This anti-aging serum is formulated around Acetyl Hexapeptide-8 and Ferulic
Slurp Hyaluid Versus Naturium Multi-Peptide Advanced Serum
This hydrating serum is formulated around Sodium Hyaluronate and Niacinamide to hydrate skin and strengthen the skin barrier.
This anti-aging serum is formulated around Acetyl Hexapeptide-8 and Ferulic Acid to soften the look of wrinkles.
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Erythritol
1,2-Hexanediol
Propanediol
Sodium Hyaluronate
Caesalpinia Spinosa Fruit Extract
Chlorphenesin
Niacinamide
Betaine
Allantoin
Kappaphycus Alvarezii Extract
Hydrolyzed Collagen
Asiaticoside
Glycerin
Adenosine
Xylitylglucoside
Ethylhexylglycerin
Anhydroxylitol
Butylene Glycol
Dextrin
Xylitol
3-O-Ethyl Ascorbic Acid
Panthenol
Hydrolyzed Elastin
Glucose
Pentylene Glycol
Cynanchum Atratum Extract
Sodium Chloride
Madecassoside
Sodium Deoxycholate
Disodium Phosphate
Sodium Phosphate
Hydroxypropyltrimonium Hyaluronate
Sr-(Oligopeptide-91 Clostridium Botulinum Polypeptide-1)
Polysorbate 20
Sodium Acetylated Hyaluronate
Hydrolyzed Hyaluronic Acid
Lecithin
Phosphatidylcholine
Acetyl Hexapeptide-8
Palmitoyl Tripeptide-1
Hyaluronic Acid
Sodium Hyaluronate Crosspolymer
Copper Tripeptide-1
Hydrolyzed Sodium Hyaluronate
Potassium Hyaluronate
Sh-Oligopeptide-2
Sh-Polypeptide-1
Sh-Polypeptide-2
Erythritol, 1,2-Hexanediol, Propanediol, Sodium Hyaluronate, Caesalpinia Spinosa Fruit Extract, Chlorphenesin, Niacinamide, Betaine, Allantoin, Kappaphycus Alvarezii Extract, Hydrolyzed Collagen, Asiaticoside, Glycerin, Adenosine, Xylitylglucoside, Ethylhexylglycerin, Anhydroxylitol, Butylene Glycol, Dextrin, Xylitol, 3-O-Ethyl Ascorbic Acid, Panthenol, Hydrolyzed Elastin, Glucose, Pentylene Glycol, Cynanchum Atratum Extract, Sodium Chloride, Madecassoside, Sodium Deoxycholate, Disodium Phosphate, Sodium Phosphate, Hydroxypropyltrimonium Hyaluronate, Sr-(Oligopeptide-91 Clostridium Botulinum Polypeptide-1), Polysorbate 20, Sodium Acetylated Hyaluronate, Hydrolyzed Hyaluronic Acid, Lecithin, Phosphatidylcholine, Acetyl Hexapeptide-8, Palmitoyl Tripeptide-1, Hyaluronic Acid, Sodium Hyaluronate Crosspolymer, Copper Tripeptide-1, Hydrolyzed Sodium Hyaluronate, Potassium Hyaluronate, Sh-Oligopeptide-2, Sh-Polypeptide-1, Sh-Polypeptide-2
Water
Caprylic/Capric Triglyceride
Isopentyldiol
Ethylhexyl Polyhydroxystearate
Squalane
Tetradecane
Glyceryl Stearate Citrate
Butyrospermum Parkii Butter
Polyglyceryl-3 Stearate
Helianthus Annuus Extract
Oryza Sativa Bran Extract
Mannitol
Ferulic Acid
Arginine
Copper Palmitoyl Heptapeptide-14
Palmitoyl Sh-Heptapeptide-12 Sp
Rosmarinus Officinalis Leaf Extract
Lactic Acid/Glycolic Acid Copolymer
Tocopherol
Pullulan
Lysolecithin
Sclerotium Gum
Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer
Dimethicone
Sodium Phytate
Diglycerin
Hydrogenated Lecithin
Silica
Cetyl Alcohol
Hydroxyacetophenone
Polysorbate 60
Sorbitan Isostearate
Sodium Hydroxide
Sodium Benzoate
Potassium Sorbate
Polyvinyl Alcohol
Decyl Glucoside
Xanthan Gum
Tocopheryl Acetate
Citric Acid
Phenoxyethanol
Water, Propanediol, Caprylic/Capric Triglyceride, Isopentyldiol, Ethylhexyl Polyhydroxystearate, Squalane, Tetradecane, Glyceryl Stearate Citrate, Butyrospermum Parkii Butter, Polyglyceryl-3 Stearate, Helianthus Annuus Extract, Oryza Sativa Bran Extract, Mannitol, Phosphatidylcholine, Ferulic Acid, Arginine, Acetyl Hexapeptide-8, Copper Palmitoyl Heptapeptide-14, Palmitoyl Sh-Heptapeptide-12 Sp, Hydrolyzed Collagen, Rosmarinus Officinalis Leaf Extract, Lactic Acid/Glycolic Acid Copolymer, Glycerin, Tocopherol, Pullulan, Lysolecithin, Sclerotium Gum, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Dimethicone, Sodium Phytate, Diglycerin, Hydrogenated Lecithin, Silica, Cetyl Alcohol, Hydroxyacetophenone, Polysorbate 60, Sorbitan Isostearate, Sodium Hydroxide, Sodium Benzoate, Potassium Sorbate, Polyvinyl Alcohol, Decyl Glucoside, Xanthan Gum, Tocopheryl Acetate, Sodium Chloride, Citric Acid, Phenoxyethanol
Reviews
Alternatives
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Acetyl Hexapeptide-8 (also known as Argireline) is a synthetic hexapeptide that is often called a "topical Botox alternative".
It works by mimicking how Botox relaxes muscles; it interferes with the signaling process that tells your facial muscles to contract. This can help soften expression lines like forehead wrinkles or crow's feet over time.
The comparison to Botox does have limits because the molecule is water-loving and relatively large.
Acetyl Hexapeptide-8 has a hard time absorbing deeply enough through the skin's outer barrier to actually reach the muscles.
So whether it truly works the way Botox does at a biological level is still up for debate, but early clinical outcomes are fairly encouraging.
A 12 week human study of a multi-ingredient regimen containing this ingredient saw:
While some studies have observed improvements in wrinkle appearance, it is important to note that more consistent results are seen in multi-ingredient formulations (vs just Acetyl Hexapeptide-8 alone).
Some research studies also used higher concentrations (up to 10%) while this ingredient is usually found in concentrations up to 0.005% in leave-on formulations.
Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Hydrolyzed Collagen is Collagen (usually sourced from fish, bovine, or porcine byproducts) that's been broken down into smaller peptides. This makes it water-soluble and easy to blend into formulations.
In a formula, it works mainly as a skin-conditioning and moisturizing agent.
The small peptides and amino acids (including Natural Moisturizing Factor components like Hydroxyproline, Serine, and Aspartic Acid) help the surface of the skin hold onto water, feel softer, and look temporarily plumper.
This ingredient also has mild film-forming and antioxidant properties with research showing the antioxidant effect is stronger the lower the molecular weight of the peptides.
It's worth being realistic here:
Topically applied Hydrolyzed Collagen conditions the upper layers of skin rather than rebuilding the structural collagen deep in your dermis (the wrinkle-and-firmness benefits people associate with Collagen mostly come from oral supplements in studies, not topicals).
However, recent lab and skin-model work on Hydrolyzed Fish Collagen has shown promising effects on cell viability and wound healing when used as an active.
Typical concentrations range from 0.2-2%, but the percentage can go much higher in rinse-off or hair products (sometimes even above 50%).
Clinical studies on this ingredient showed no irritation, sensitization, or phototoxicity.
If you are looking for vegan collagen, it usually goes by a different INCI name like hydrolyzed soy protein. Vegan collagen is derived from yeast, bacteria, or plant sources.
The results are varied.
A study from 2021 found hydrolyzed collagen increased elasticity and improved wrinkles in 1,125 participants between age 20 and 70. Another study found increased skin thickness in participants between the ages of 45 to 59.
However, It is difficult to prove that oral collagen will end up working on your skin. Many of the studies using hydrolyzed collagen also add several vitamins and nutrients into the test mixture as well.
Further studies are needed at this time.
Phosphatidylcholine (PC) is a type of phospholipid, a class of molecule that makes up our own cell membranes.
It has a glycerol backbone, two fatty acid tails (mostly linoleic, palmitic, and oleic), and a phosphate-choline head group.
In skincare, PC pulls double duty:
The linoleic acid it carries gets incorporated into skin ceramides and helps reinforce the lipid matrix.
Interestingly, it can help top of the omega-6 fatty acid that's often low in acne-prone and atopic skin. There's a sizeable body of literature that supports its use in dry, barrier-impaired, and breakout-prone skin.
There are two kinds of PC you'll see on ingredient lists.
Use levels range from <1% as a liposomal carrier and between 20-40% in lamellar matrix sytems.
Propanediol is an all-star ingredient. It softens, hydrates, and smooths the skin.
It’s often used to:
Propanediol is not likely to cause sensitivity and considered safe to use. It is derived from corn or petroleum with a clear color and no scent.
Chances are, you eat sodium chloride every day. Sodium Chloride is also known as table salt. This ingredient has many purposes in skincare: thickener, emulsifier, and exfoliator.
You'll most likely find this ingredient in cleansers where it is used to create a gel-like texture. As an emulsifier, it also prevents ingredients from separating.
You might see people debate whether Sodium Chloride is comedogenic, but there actually haven't been any comedogenic tests done on it. Either way, the overall formulation of a product matters a lot more than any single ingredient.
You might see this ingredient used in scrubs as a primary exfoliating ingredient.