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Skin science article

The INKEY List Alpha Arbutin Serum Versus Topicals Faded Brightening + Clearing Serum

The INKEY List Alpha Arbutin Serum Versus Topicals Faded Brightening + Clearing Serum This brightening serum is formulated around Alpha-Arbutin to fade the look of dark spots and brighten dull-looking skin. This brightening serum is formulated around Niacinami

The INKEY List Alpha Arbutin Serum Versus Topicals Faded Brightening + Clearing Serum

This brightening serum is formulated around Alpha-Arbutin to fade the look of dark spots and brighten dull-looking skin.

This brightening serum is formulated around Niacinamide and Tranexamic Acid to fade the look of dark spots and brighten dull-looking skin.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Butylene Glycol

Propanediol

Glycerin

Alpha-Arbutin

Dicaprylyl Carbonate

Caprylic/Capric Triglyceride

Phenoxyethanol

Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer

Caprylyl Glycol

Squalane

Phospholipids

Glycine Soja Oil

Carbomer

Polysorbate 60

Sodium Phytate

Glycolipids

Sorbitan Isostearate

Leuconostoc/Radish Root Ferment Filtrate

Sodium Hydroxide

Glycine Soja Sterols

Hyaluronic Acid

Tocopherol

Water, Butylene Glycol, Propanediol, Glycerin, Alpha-Arbutin, Dicaprylyl Carbonate, Caprylic/Capric Triglyceride, Phenoxyethanol, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Caprylyl Glycol, Squalane, Phospholipids, Glycine Soja Oil, Carbomer, Polysorbate 60, Sodium Phytate, Glycolipids, Sorbitan Isostearate, Leuconostoc/Radish Root Ferment Filtrate, Sodium Hydroxide, Glycine Soja Sterols, Hyaluronic Acid, Tocopherol

Niacinamide

Butyrospermum Parkii Butter

Tranexamic Acid

Glyceryl Stearate

Arbutin

Simmondsia Chinensis Seed Oil

Behenyl Alcohol

Glyceryl Behenate

Kojic Acid

Oxidized Glutathione

Ceteareth-20

Lecithin

Sclerotium Gum

Zinc Ricinoleate

Arginine Hcl

Azelaic Acid

Ceteareth-12

Cetearyl Alcohol

Cetyl Palmitate

Tetrahydroxypropyl Ethylenediamine

Curcuma Longa Root Extract

Sodium Lauroyl Sarcosinate

Trisodium Ethylenediamine Disuccinate

Phytic Acid

Allantoin

Dimethylmethoxy Chromanyl Palmitate

Ethylhexylglycerin

Centella Asiatica Leaf Extract

Melatonin

Glycyrrhiza Glabra Root Extract

Water, Caprylic/Capric Triglyceride, Glycerin, Niacinamide, Butyrospermum Parkii Butter, Tranexamic Acid, Glyceryl Stearate, Arbutin, Simmondsia Chinensis Seed Oil, Behenyl Alcohol, Glyceryl Behenate, Kojic Acid, Oxidized Glutathione, Phenoxyethanol, Ceteareth-20, Lecithin, Sclerotium Gum, Zinc Ricinoleate, Arginine Hcl, Azelaic Acid, Squalane, Ceteareth-12, Cetearyl Alcohol, Cetyl Palmitate, Tetrahydroxypropyl Ethylenediamine, Curcuma Longa Root Extract, Sodium Lauroyl Sarcosinate, Trisodium Ethylenediamine Disuccinate, Phytic Acid, Allantoin, Dimethylmethoxy Chromanyl Palmitate, Ethylhexylglycerin, Centella Asiatica Leaf Extract, Melatonin, Glycyrrhiza Glabra Root Extract

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Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Caprylic/Capric Triglyceride (aka MCT Oil) is a lightweight emollient, solvent, and texture enhancer. It is considered a skin-softener by helping to prevent moisture loss.

Though it behaves like an oil, it is not technically one due to its chemical composition. One perk of this ingredient is that it is very stable, resistant to oxidation, and unlikely to go rancid.

In practice, that translates to a long shelf life and a consistently elegant skin feel.

While there is an assumption Caprylic Triglyceride can clog pores due to it being derived from coconut oil, there is no research supporting this. Just patch test if you have concerns.

Fractionated coconut oil and MCT Oil are both listed as Caprylic/Capric Triglyceride according to INCI. This is because INCI names are based on the ingredient’s final chemical composition and not its marketing name or source.

This ingredient is treated as the gold standard fungal acne safe oil. Even though it is coconut derived, the problematic lauric acid is stripped out.

This leaves just caprylic (C8) and capric (C10) acid. These chain lengths actually trend antifungal; a 2020 study found caprylic acid was enough to disrupt Malassezia furfur cell membrane, with a caprylic acid derivative damaging membrane structures at concentrations as low as 0.2%.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).

It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.

On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.

Another perk of this ingredient is that it stays functional across a wide pH range (3-10).

You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.

Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.

Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.

Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.

Squalane is the hydrogenated and shelf-stable form of squalene (a lipid that naturally occurs in human sebum).

It is an emollient and skin conditioning agent that is able to integrate seamlessly into the skin's lipid barrier without clogging pores.

This is due to how structurally similar it is to what your skin already produces.

Though it is mostly an emollient that helps soften and hydrate skin, it also has some humectant and occlusive action. Humectants help the skin retain moisture while occlusives seal it in, making squalane a triple-threat moisturizer.

Research shows it has antioxidant capabilities that help protect against stressors like UV exposure, specifically UVA induced oxidative stress. This study also found that it supports collagen biosynthesis in human dermal fibroblasts.

No clinical study has reported significant adverse effects and irritation reactions are very rare from this ingredient (even at 100% concentration).

Overall, it's a fantastic ingredient for hydration and is suitable for all skin types.

This depends on the source. Squalane can be derived from both plants and animals. Most squalane used in skincare comes from plants.

Please note: the source of squalane is only known if disclosed by the brand. We recommend reaching out to the brand if you have any questions about their squalane.

Read more about squalene with an "e".

Though squalane is often called an oil, it’s technically not one. It is a hydrocarbon, meaning it is only made of carbon and hydrogen. True oils are triglycerides and made of fatty acids and glycerol.

The term “oil-free” isn’t regulated so companies can define it however they want. Some exclude all oils, while others just avoid mineral oil or comedogenic oils.

Squalane has a comedogenic rating of 1 from the original 1972 study that tested raw ingredients under occlusion on rabbit ears. This system is not standardized or peer-reviewed, and using the raw ingredients is very different from how diluted cosmetic formulations are used on human skin.

A comedogenic rating of 1 means it is "unlikely to clog pores" according to the original rating system.

The overall formula of a product matters more than the individual ingredients on whether or not it will cause clogged pores.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

Similar Comparisons

The reference edit

Ingredients, questions
& further reading.

Connected source records selected through this article’s public topic index.

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Formula cabinet

Ingredients & structured notes

Ingredient index

Ingredients Explained

  1. 01These ingredients are found in both products.
  2. 02Ingredients higher up in an ingredient list are typically present in a larger amount.
  3. 03Ethylhexylglycerin is created from glycerin. It is a multitasker ingredient that:
  4. 04The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure …
  5. 05Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.
  6. 06Panthenol is a common ingredient that helps hydrate and soothe the skin. It is found naturally in our skin and hair.
  7. 07There are two forms of panthenol: D and L.
  8. 08D-panthenol is also known as dexpanthenol. Most cosmetics use dexpanthenol or a mixture of D and L-panthenol.
  9. 09Panthenol is famous due to its ability to go deeper into the skin's layers. Using this ingredient has numerous pros (and no cons):
  10. 10Like hyaluronic acid, panthenol is a humectant. Humectants are able to bind and hold large amounts of water to keep skin hydrated.
  11. 11This ingredient works well for wound healing. It works by increasing tissue in the wound and helps close open wounds.
  12. 12Once oxidized, panthenol converts to pantothenic acid. Panthothenic acid is found in all living cells.
  13. 13This ingredient is also referred to as pro-vitamin B5.
  14. 14Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).
  15. 15It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.
  16. 16On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.
  17. 17Another perk of this ingredient is that it stays functional across a wide pH range (3-10).
  18. 18You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.
  19. 19Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.
  20. 20Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.
Source · skinsort.com
02

Product index

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Comparison edit

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