Skin science article
The INKEY List Retinol Eye Cream Versus Pacifica Wake Up Beautiful Retinoid Serum
The INKEY List Retinol Eye Cream Versus Pacifica Wake Up Beautiful Retinoid Serum This anti-aging eye moisturizer is formulated around Retinol and Sodium Hyaluronate to soften the look of wrinkles and refine skin texture. This anti-aging serum is formulated ar
The INKEY List Retinol Eye Cream Versus Pacifica Wake Up Beautiful Retinoid Serum
This anti-aging eye moisturizer is formulated around Retinol and Sodium Hyaluronate to soften the look of wrinkles and refine skin texture.
This anti-aging serum is formulated around Hydroxypinacolone Retinoate to soften the look of wrinkles and refine skin texture.
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Caprylic/Capric Triglyceride
Glycerin
Butylene Glycol
Pentaerythrityl Distearate
Shea Butter Ethyl Esters
Cetearyl Olivate
Phenoxyethanol
Benzyl Alcohol
Sorbitan Olivate
Acrylates/C10-30 Alkyl Acrylate Crosspolymer
Sodium Hydroxide
Sodium Hyaluronate
Sodium Stearoyl Glutamate
Copernicia Cerifera Cera
Propanediol
Glycogen
Sodium Gluconate
Retinol
Polysorbate 20
Ethylhexylglycerin
Dehydroacetic Acid
Citric Acid
Helianthus Annuus Seed Oil
1,2-Hexanediol
Caprylyl Glycol
Disodium Cocoamphodiacetate
Tocopherol
Xanthan Gum
Ethyl Ferulate
Humulus Lupulus Extract
Water, Caprylic/Capric Triglyceride, Glycerin, Butylene Glycol, Pentaerythrityl Distearate, Shea Butter Ethyl Esters, Cetearyl Olivate, Phenoxyethanol, Benzyl Alcohol, Sorbitan Olivate, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Sodium Hydroxide, Sodium Hyaluronate, Sodium Stearoyl Glutamate, Copernicia Cerifera Cera, Propanediol, Glycogen, Sodium Gluconate, Retinol, Polysorbate 20, Ethylhexylglycerin, Dehydroacetic Acid, Citric Acid, Helianthus Annuus Seed Oil, 1,2-Hexanediol, Caprylyl Glycol, Disodium Cocoamphodiacetate, Tocopherol, Xanthan Gum, Ethyl Ferulate, Humulus Lupulus Extract
Hydroxypinacolone Retinoate
Rosa Centifolia Flower Extract
Calendula Officinalis Flower Extract
Chamomilla Recutita Flower Extract
Ganoderma Lucidum Extract
Trametes Versicolor Extract
Chenopodium Quinoa Seed Extract
Melatonin
Oryza Sativa Bran Extract
Helianthus Annuus Extract
Rosmarinus Officinalis Leaf Extract
Linoleic Acid
Phytosterols
Phospholipids
Jojoba Esters
Acacia Senegal Gum
Dimethyl Isosorbide
Methylheptylglycerin
Caprylhydroxamic Acid
Water, Propanediol, Helianthus Annuus Seed Oil, Cetearyl Olivate, Sorbitan Olivate, Hydroxypinacolone Retinoate, Rosa Centifolia Flower Extract, Calendula Officinalis Flower Extract, Chamomilla Recutita Flower Extract, Ganoderma Lucidum Extract, Trametes Versicolor Extract, Chenopodium Quinoa Seed Extract, Melatonin, Oryza Sativa Bran Extract, Helianthus Annuus Extract, Rosmarinus Officinalis Leaf Extract, Tocopherol, Glycerin, Linoleic Acid, Phytosterols, Phospholipids, Jojoba Esters, Caprylic/Capric Triglyceride, Sodium Hyaluronate, Xanthan Gum, Acacia Senegal Gum, Sodium Gluconate, Dimethyl Isosorbide, Methylheptylglycerin, Caprylhydroxamic Acid, Caprylyl Glycol, Citric Acid
Reviews
Alternatives
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Caprylic/Capric Triglyceride (aka MCT Oil) is a lightweight emollient, solvent, and texture enhancer. It is considered a skin-softener by helping to prevent moisture loss.
Though it behaves like an oil, it is not technically one due to its chemical composition. One perk of this ingredient is that it is very stable, resistant to oxidation, and unlikely to go rancid.
In practice, that translates to a long shelf life and a consistently elegant skin feel.
While there is an assumption Caprylic Triglyceride can clog pores due to it being derived from coconut oil, there is no research supporting this. Just patch test if you have concerns.
Fractionated coconut oil and MCT Oil are both listed as Caprylic/Capric Triglyceride according to INCI. This is because INCI names are based on the ingredient’s final chemical composition and not its marketing name or source.
This ingredient is treated as the gold standard fungal acne safe oil. Even though it is coconut derived, the problematic lauric acid is stripped out.
This leaves just caprylic (C8) and capric (C10) acid. These chain lengths actually trend antifungal; a 2020 study found caprylic acid was enough to disrupt Malassezia furfur cell membrane, with a caprylic acid derivative damaging membrane structures at concentrations as low as 0.2%.
Caprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created.
Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin.
Because it is not a free-fatty acid, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on).
Cetearyl Olivate is a plant-derived emulsifier and texture enhancer. It helps keep the oil and water phases from separating so your formulas stay stable.
You'll likely see it combined with Sorbitan Olivate (together sold as the trade name Olivem 1000). This combination generates a liquid crystal structure that closely resemble the lipid organization of the stratum corneum.
These "skin-like" liquid crystals improve skin barrier integrity and promote the delivery of actives into the skin.
This ingredient is well-tolerated and has no significant sensitization data.
Because it is derived from the fatty acids in olive oil, this ingredient may not be fungal acne safe.
Citric Acid is an alpha hydroxy acid (AHA) naturally found in citrus fruits like oranges, lemons, and limes.
Like other AHAs, citric acid can exfoliate skin by breaking down the bonds that hold dead skin cells together. This helps reveal smoother and brighter skin underneath.
However, this exfoliating effect only happens at high concentrations (20%) which can be hard to find in cosmetic products.
Due to this, citric acid is usually included in small amounts as a pH adjuster. This helps keep products slightly more acidic and compatible with skin's natural pH.
In skincare formulas, citric acid can:
While it can provide some skin benefits, research shows lactic acid and glycolic acid are generally more effective and less irritating exfoliants.
Most citric acid used in skincare today is made by fermenting sugars (usually from molasses). This synthetic version is identical to the natural citrus form but easier to stabilize and use in formulations.
Rosacea skin has a lower threshold for acids generally, with 62.5% of rosacea subjects in one study reacting to lactic acid in a sting test. This is why we mark citric acid as a potential rosacea trigger.
However, this ingredient shows up as a pH adjuster or chelator at roughly 0.1-1% in many products. These low levels are unlikely to be an issue for rosacea skin and becomes a potential trigger at exfoliating concentrations (20%). Because everybody's skin is unique, we recommend a patch test if you are unsure.
Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Helianthus Annuus Seed Oil is a plant oil derived from the seeds of a sunflower.
It is rich in fatty acids, primarily linoleic acid and oleic acid. This gives it emollient and skin conditioning properties.
The reason this ingredient is so effective is because it forms a thin film on the skin that reduces transepidermal water loss (TEWL) while supplying linoleic acid to the stratum corneum to improve barrier strength.
The high linoleic acid content is particularly noteworthy for acne-prone skin.
Research suggests that acne-prone skin tends to be deficient in linoleic acid in sebum. Topical application may help replenish this to support a healthier follicular environment and less comedone-promoting sebum.
One randomized study found sunflower seed oil preserved skin barrier integrity in adult volunteers with and without atopic dermatitis (outperforming olive oil).
This ingredient is well-studied, gentle, and an effective emollient suitable for most skin types.
On fungal acne: This ingredient may not be Fungal acne (Malassezia folliculitis) safe. This is because it contains fatty acids with carbon chain lengths in the C11-C24 range.
Propanediol is an all-star ingredient. It softens, hydrates, and smooths the skin.
It’s often used to:
Propanediol is not likely to cause sensitivity and considered safe to use. It is derived from corn or petroleum with a clear color and no scent.
This is the synthetic salt of gluconic acid, a form of PHA and mild exfoliant.
It is mainly used to stabilize oil and butter formulations from going bad. Sodium gluconate is a humectant, pH regulator, and chelating agent.
Chelating agents help neutralize unwanted metals from affecting the formulation.
Sodium gluconate is water-soluble.
Sodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity.
In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface.
Interestingly, the size of the molecule affects its behavior:
Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.
Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.
You'll typically see concentrations between 0.1-2% for this ingredient.
Sorbitan Olivate is created from the fatty acids in olive oil and sorbitol.
This ingredient is an oil in water emulsifier. It helps stabilize a product by preventing oils and waters from separating. Sorbitan Olivate also helps hydrate the skin.
This ingredient is also known as part of Olivem 1000, with Cetearyl Olivate being the other part.
According to a manufacturer, this ingredient helps preserve the natural microbiome of skin. Having a healthy microbiome helps keep our skin healthy and protects against harmful bacteria.
Please note, having a healthy microbiome is different from fungal acne; a healthy microbiome includes small amounts of yeast that normally live on your skin without causing problems.
Fungal acne happens when one type of yeast (Malassezia) grows out of control. This is usually because it's feeding on certain oils or fatty acids. Due to the olive oil base, this ingredient may not be fungal acne safe.
Tocopherol is a fat-soluble antioxidant known as Vitamin E.
You'll find this ingredient in the vast majority of skincare (for good reason). It works to neutralize free radicals, or unstable molecules generated by UV exposure, pollution, and other environmental stressors, before they can cause oxidative damage to your skin cells.
Topically applied tocopherol has been shown to protect against UV damage by ramping up the skin's own natural defense enzymes.
It also acts as a skin conditioning agent; some studies show that regular topical use can improve the skin's water-binding capacity over 2-4 weeks.
This ingredient is especially loved for being a team player. When combined with Vitamin C, the photoprotective effect of both ingredients roughly doubles and the combo also helps reduce UV-induced DNA damage.
This ingredient has some brightening potential but it's more of a prevention ingredient than spot-fader. Cell studies show it can slow down melanin production but it's worth noting that it's not the most powerful brightener out there.
In formulations, it also serves as a stabilizer that helps protect other oxidation-prone ingredients from degrading.
Concentrations usually range from 0.1-1% in most leave-on products.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!
Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.
On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.
Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.