Ingredient or product comparison
Best GHK-Cu Dosage for Anti-Aging: Dosing Comparison
0.5–1mg Mild stimulation. Decorin upregulation without significant MMP activation Minimal First-time users, skin maintenance phase post-correction Once daily, morning Safe starting point but may underwhelm users seeking visible correction within 8 weeks 1.5–2m
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- 0.5–1mg
- Mild stimulation. Decorin upregulation without significant MMP activation
- Minimal
- First-time users, skin maintenance phase post-correction
- Once daily, morning
- Safe starting point but may underwhelm users seeking visible correction within 8 weeks
- 1.5–2mg
- 60–70% increase in Type I collagen production, lysyl oxidase activation
- Low if pulsed (5 days on, 2 off)
- Primary anti-aging protocol for skin elasticity and wound healing
- Once daily, morning or split AM/PM
- Optimal balance. Clinically supported, minimal oxidative risk, visible outcomes within 6–8 weeks
- 2.5–3mg
- Peak receptor occupancy. No additional collagen benefit vs 2mg
- Moderate if continuous dosing
- Advanced protocols for tissue repair post-injury or surgical healing
- Once daily, morning only
- Upper therapeutic limit. Exceeding this dose provides no added collagen synthesis but increases copper load
- 3.5mg+
- Receptor saturation. Excess copper catalyses oxidative stress
- High
- Not recommended for anti-aging
- Not applicable
- Doses above 3mg daily offer zero therapeutic advantage and elevate pro-oxidant activity