Ingredient or product comparison
Best GHK-Cu Dosage for Wound Healing: Comparison
Superficial epidermal (first-degree) 0.5–1mg once daily Topical to wound bed 5–10 days 20–30% faster re-epithelialization Low bioavailability but sufficient for keratinocyte migration Partial-thickness dermal (second-degree) 1–1.5mg once daily Topical or subcu
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- Superficial epidermal (first-degree)
- 0.5–1mg once daily
- Topical to wound bed
- 5–10 days
- 20–30% faster re-epithelialization
- Low bioavailability but sufficient for keratinocyte migration
- Partial-thickness dermal (second-degree)
- 1–1.5mg once daily
- Topical or subcutaneous near margin
- 10–18 days
- 25–35% faster closure, reduced scar formation
- Subcutaneous preferred if wound exudate is heavy
- Full-thickness dermal (third-degree)
- 1.5–2.5mg once daily
- Subcutaneous 2–5mm from wound edge
- 21–35 days
- 30–40% increased granulation tissue, improved tensile strength
- Peak dosing during proliferative phase (days 3–14)
- Chronic non-healing ulcers
- 2–3mg divided twice daily
- Subcutaneous, avoid necrotic tissue
- 28–56 days minimum
- 35–50% reduction in wound area, variable by underlying pathology
- MMP activity degrades peptide faster; split dosing maintains levels
- Post-surgical incisions
- 1–2mg once daily
- Subcutaneous along incision line
- 14–21 days
- Reduced hypertrophic scarring, 15–20% faster return to baseline tensile strength
- Begin on post-op day 2 once hemostasis confirmed