Ingredient or product comparison
GHK-Cu Dosing Across Wound Types: Comparison
Superficial epidermal (abrasions, minor burns) 200–300 µg/mL Twice daily days 0–5, once daily days 6–14 7–14 days Cost-effective for rapid re-epithelialization; minimal scar risk justifies lower concentration Partial-thickness dermal (donor sites, deep lacerat
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- Superficial epidermal (abrasions, minor burns)
- 200–300 µg/mL
- Twice daily days 0–5, once daily days 6–14
- 7–14 days
- Cost-effective for rapid re-epithelialization; minimal scar risk justifies lower concentration
- Partial-thickness dermal (donor sites, deep lacerations)
- 500–750 µg/mL
- Twice daily days 0–5, once daily days 6–21
- 14–21 days
- Sweet spot for collagen synthesis stimulation; prevents hypertrophic scarring when applied consistently
- Full-thickness wounds (surgical incisions, third-degree burns)
- 1–2 mg/mL
- Twice daily days 0–10, once daily days 11–30
- 21–45 days
- Highest concentration justified by depth; essential during matrix remodelling window (days 7–21)
- Chronic non-healing wounds (diabetic ulcers, pressure sores)
- 2–5 mg/mL in hydrogel
- Once daily continuously until closure
- 8–16 weeks
- Requires sustained high-dose to overcome senescent cell phenotype; hydrogel carrier critical for penetration
- Post-surgical aesthetic (facelift, blepharoplasty)
- 300–500 µg/mL
- Once daily days 1–30
- 30–60 days
- Moderate concentration balances healing speed with scar minimization; aesthetic outcomes justify extended treatment
- The bottom line: match concentration to tissue depth, not wound surface area. A 10 cm² superficial abrasion requires less peptide per application than a 2 cm² full-thickness punch biopsy site.