Peptide Skincare & BeautySkin science and ingredient guides

Ingredient or product comparison

Naturium Retinaldehyde Cream Serum 0.05% Versus One Thing Peptide Retinal Serum

Naturium Retinaldehyde Cream Serum 0.05% Versus One Thing Peptide Retinal Serum Detailed comparison of Naturium Retinaldehyde Cream Serum 0.05% versus One Thing Peptide Retinal Serum. This anti-aging serum is formulated around Retinal to soften the look of wri

This source-based comparison does not add ratings or recommend a winner.

Naturium Retinaldehyde Cream Serum 0.05% Versus One Thing Peptide Retinal Serum Detailed comparison of Naturium Retinaldehyde Cream Serum 0.05% versus One Thing Peptide Retinal Serum. This anti-aging serum is formulated around Retinal to soften the look of wrinkles and refine skin texture. This anti-aging serum is formulated around Niacinamide and Palmitoyl Tripeptide-5 to soften the look of wrinkles and refine skin texture. Water Glycerin Propanediol Triheptanoin C13-15 Alkane Coco-Caprylate/Caprate Carbomer Faex Extract Apricot Kernel Oil Polyglyceryl-6 Esters Soy Amino Acids Punica Granatum Seed Extract Cetyl Diglyceryl Tris(Trimethylsiloxy)Silylethyl Dimethicone Hydrolyzed Yeast Extract Olivine Extract Dilinoleic Acid/Butanediol Copolymer Cellulose Phenoxyethanol Sorbitan Oleate Sodium Metabisulfite Retinal Guanosine Uracil Polyacrylate Crosspolymer-6 C9-12 Alkane Caprylyl Glycol Polyglyceryl-10 Dipalmitate Dipropylene Glycol Sodium Hydroxide Glyceryl Polyacrylate Tocopherol Pvm/Ma Copolymer Adenosine Phosphate Castor Oil/Ipdi Copolymer Potassium Sorbate Hexadecene Sodium Benzoate T-Butyl Alcohol Water, Glycerin, Propanediol, Triheptanoin, C13-15 Alkane, Coco-Caprylate/Caprate, Carbomer, Faex Extract, Apricot Kernel Oil Polyglyceryl-6 Esters, Soy Amino Acids, Punica Granatum Seed Extract, Cetyl Diglyceryl Tris(Trimethylsiloxy)Silylethyl Dimethicone, Hydrolyzed Yeast Extract, Olivine Extract, Dilinoleic Acid/Butanediol Copolymer, Cellulose, Phenoxyethanol, Sorbitan Oleate, Sodium Metabisulfite, Retinal, Guanosine, Uracil, Polyacrylate Crosspolymer-6, C9-12 Alkane, Caprylyl Glycol, Polyglyceryl-10 Dipalmitate, Dipropylene Glycol, Sodium Hydroxide, Glyceryl Polyacrylate, Tocopherol, Pvm/Ma Copolymer, Adenosine Phosphate, Castor Oil/Ipdi Copolymer, Potassium Sorbate, Hexadecene, Sodium Benzoate, T-Butyl Alcohol Butylene Glycol Niacinamide Caprylic/Capric Triglyceride Cetyl Ethylhexanoate Vinyldimethicone Glyceryl Polymethacrylate 1,2-Hexanediol Betaine C14-22 Alcohols Cetearyl Olivate Glyceryl Stearate Hydroxyacetophenone Propylene Glycol Sorbitan Olivate Acrylates/C10-30 Alkyl Acrylate Crosspolymer Tromethamine C12-20 Alkyl Glucoside Ethylhexylglycerin Adenosine Hydrolyzed Gardenia Florida Extract Hydrolyzed Malt Extract Hydrolyzed Viola Tricolor Extract Sodium Polyacrylate Dextrin Disodium EDTA Sodium Polyacryloyldimethyl Taurate Gardenia Florida Fruit Extract Hyaluronic Acid Hydrolyzed Hyaluronic Acid Sodium Hyaluronate Hydrogenated Polydecene Hydrogenated Lecithin Polyglyceryl-10 Oleate Sodium Lactate Trideceth-10 Palmitoyl Tripeptide-5 Polysorbate 20 Sodium Ascorbyl Phosphate Palmitoyl Tripeptide-1 Palmitoyl Tetrapeptide-7 Copper Tripeptide-1 Palmitoyl Pentapeptide-4 Acetyl Hexapeptide-8 Macadamia Ternifolia Seed Oil Phosphatidylcholine Cholesterol Phytosteryl/Behenyl/Octyldodecyl Lauroyl Glutamate Aluminum/Magnesium Hydroxide Stearate Brassica Campestris Sterols Potassium Cetyl Phosphate Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate Water, Butylene Glycol, Niacinamide, Caprylic/Capric Triglyceride, Dipropylene Glycol, Cetyl Ethylhexanoate, Propanediol, Vinyldimethicone, Glycerin, Glyceryl Polymethacrylate, 1,2-Hexanediol, Betaine, C14-22 Alcohols, Cetearyl Olivate, Glyceryl Stearate, Hydroxyacetophenone, Propylene Glycol, Sorbitan Olivate, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Tromethamine, C12-20 Alkyl Glucoside, Ethylhexylglycerin, Polyacryla These ingredients are found in both products. Ingredients higher up in an ingredient list are typically present in a larger amount. Carbomer is a synthetic thickening and gelling agent. It's basically the ingredient that gives a lot of serums, gels, creams, and sunscreens their smooth, non-sticky texture. Although legally permitted at very high levels, carbomers are normally used at concentrations below 1%. It also needs to be neutralized to actually thicken, and because it is a large molecule, it doesn't really penetrate the skin barrier. Allergy-wise, the risk is very low. Clinical studies show carbomers have low potential for skin irritation/sensitization even at concentrations up to 100%. A 2024 UK study patch-tested 1,302 patients and found true allergy to the parent group of carbomer to be rare with no confirmed relevant reactions. Dipropylene Glycol is a synthetically created humectant, stabilizer, and solvent. This ingredient helps: Dipropylene glycol is technically an alcohol, but it belongs to the glycol family (often considered part of the ‘good’ alcohols). This means it is hydrating and gentle on skin unlike drying solvent alcohols like denatured alcohol. As a masking agent, Dipropylene Glycol can be used to cover the smell of other ingredients. However, it does not have a scent. Studies show Dipropylene Glycol is considered safe to use in skincare. Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum. Topically, glycerin does several things at once: Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3. Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin. This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products. Just know very high concentrations (>40%) can feel tacky in low humidity. Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine. Polyacrylate Crosspolymer-6 is a texture enhancer and pH adjuster. It is be used to thicken water-based products and create a gel-texture with a velvet feel. One manufacturer claims this ingredient to have a pH range of 2-8 and to be biodegradable. This ingredient is also known as Sepimax Zen. Propanediol is an all-star ingredient. It softens, hydrates, and smooths the skin. It’s often used to: Propanediol is not likely to cause sensitivity and considered safe to use. It is derived from corn or petroleum with a clear color and no scent. Retinal (aka retinaldehyde) is a form of retinoid that formulators use mainly as an antiaging and skin-renewing active. What makes it special is it