Skin science article
La Roche-Posay Effaclar Duo (+) Corrective Unclogging Care Versus D'Alba Peptide No Sebum Repair Cream
La Roche-Posay Effaclar Duo (+) Corrective Unclogging Care Versus D'Alba Peptide No Sebum Repair Cream This acne moisturizer is formulated around Niacinamide and Zinc PCA to clear breakouts and refine the look of pores. This oil-control moisturizer is formulat
La Roche-Posay Effaclar Duo (+) Corrective Unclogging Care Versus D'Alba Peptide No Sebum Repair Cream
This acne moisturizer is formulated around Niacinamide and Zinc PCA to clear breakouts and refine the look of pores.
This oil-control moisturizer is formulated around Niacinamide and Acetyl Hexapeptide-8 to balance excess oil and strengthen the skin barrier.
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Glycerin
Dimethicone
Isocetyl Stearate
Niacinamide
Isopropyl Lauroyl Sarcosinate
Silica
Ammonium Polyacryloyldimethyl Taurate
Methyl Methacrylate Crosspolymer
Potassium Cetyl Phosphate
Sorbitan Oleate
Zinc PCA
Glyceryl Stearate Se
Isohexadecane
Sodium Hydroxide
Myristyl Myristate
2-Oleamido-1,3-Octadecanediol
Aluminum Starch Octenylsuccinate
Mannose
Poloxamer 338
Disodium EDTA
Capryloyl Salicylic Acid
Caprylyl Glycol
Vitreoscilla Ferment
Xanthan Gum
Polysorbate 80
Acrylamide/Sodium Acryloyldimethyltaurate Copolymer
Salicylic Acid
Piroctone Olamine
Parfum
Water, Glycerin, Dimethicone, Isocetyl Stearate, Niacinamide, Isopropyl Lauroyl Sarcosinate, Silica, Ammonium Polyacryloyldimethyl Taurate, Methyl Methacrylate Crosspolymer, Potassium Cetyl Phosphate, Sorbitan Oleate, Zinc PCA, Glyceryl Stearate Se, Isohexadecane, Sodium Hydroxide, Myristyl Myristate, 2-Oleamido-1,3-Octadecanediol, Aluminum Starch Octenylsuccinate, Mannose, Poloxamer 338, Disodium EDTA, Capryloyl Salicylic Acid, Caprylyl Glycol, Vitreoscilla Ferment, Xanthan Gum, Polysorbate 80, Acrylamide/Sodium Acryloyldimethyltaurate Copolymer, Salicylic Acid, Piroctone Olamine, Parfum
Butylene Glycol
Caprylic/Capric Triglyceride
Squalane
1,2-Hexanediol
Cetearyl Olivate
Sorbitan Olivate
Cetearyl Alcohol
Cetearyl Glucoside
Carbomer
Hydroxypropyl Methylcellulose
Artemisia Annua Extract
Nelumbo Nucifera Flower Extract
Oryza Sativa Extract
Saccharomyces Ferment
Arginine
Octyldodecanol
Panthenol
Melaleuca Alternifolia Leaf Extract
Helianthus Annuus Seed Oil
Lavandula Angustifolia Oil
Pullulan
Tuber Magnatum Extract
Calamine
Centella Asiatica Extract
Dipotassium Glycyrrhizate
Tocopheryl Acetate
Ethylhexylglycerin
Adenosine
Sodium Hyaluronate
Hydrogenated Lecithin
Pentylene Glycol
Ceramide NP
Polygonum Cuspidatum Root Extract
Scutellaria Baicalensis Root Extract
Biosaccharide Gum-1
Alkanna Tinctoria Root Extract
Betaine Salicylate
Camellia Sinensis Leaf Extract
Glycyrrhiza Glabra Root Extract
Chamomilla Recutita Flower Extract
Porphyridium Cruentum Extract
Rosmarinus Officinalis Leaf Extract
Glucose
Sodium Hyaluronate Crosspolymer
Acetyl Hexapeptide-8
Hydrolyzed Hyaluronic Acid
Hyaluronic Acid
Tocopherol
Hydrolyzed Sodium Hyaluronate
Water, Butylene Glycol, Glycerin, Caprylic/Capric Triglyceride, Squalane, 1,2-Hexanediol, Niacinamide, Cetearyl Olivate, Sorbitan Olivate, Dimethicone, Cetearyl Alcohol, Cetearyl Glucoside, Carbomer, Hydroxypropyl Methylcellulose, Artemisia Annua Extract, Nelumbo Nucifera Flower Extract, Oryza Sativa Extract, Saccharomyces Ferment, Arginine, Octyldodecanol, Panthenol, Melaleuca Alternifolia Leaf Extract, Helianthus Annuus Seed Oil, Lavandula Angustifolia Oil, Pullulan, Tuber Magnatum Extract, Calamine, Centella Asiatica Extract, Dipotassium Glycyrrhizate, Tocopheryl Acetate, Ethylhexylglycerin, Adenosine, Sodium Hyaluronate, Hydrogenated Lecithin, Pentylene Glycol, Ceramide NP, Polygonum Cuspidatum Root Extract, Scutellaria Baicalensis Root Extract, Biosaccharide Gum-1, Alkanna Tinctoria Root Extract, Caprylyl Glycol, Betaine Salicylate, Camellia Sinensis Leaf Extract, Glycyrrhiza Glabra Root Extract, Chamomilla Recutita Flower Extract, Porphyridium Cruentum Extract, Rosmarinus Officinalis Leaf Extract, Glucose, Sodium Hyaluronate Crosspolymer, Acetyl Hexapeptide-8, Hydrolyzed Hyaluronic Acid, Hyaluronic Acid, Tocopherol, Hydrolyzed Sodium Hyaluronate
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Alternatives
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Caprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created.
Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin.
Because it is not a free-fatty acid, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on).
Dimethicone is a type of synthetic silicone created from natural materials such as quartz. It is also known as polydimethylsiloxane.
What it does:
Dimethicone comes in different viscosities:
Depending on the viscosity, dimethicone has different properties.
Ingredients lists don't always show which type is used, so we recommend reaching out to the brand if you have questions about the viscosity.
This ingredient is unlikely to cause irritation because it does not get absorbed into skin. However, people with silicone allergies should be careful about using this ingredient.
Note: Dimethicone may contribute to pilling. This is because it is not oil or water soluble, so pilling may occur when layered with products. When mixed with heavy oils in a formula, the outcome is also quite greasy.
Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Niacinamide is a multitasking form of vitamin B3 that strengthens the skin barrier, reduces pores and dark spots, regulates oil, and improves signs of aging.
And the best part? It's gentle and well-tolerated by most skin types, including sensitive and reactive skin.
You might have heard of "niacin flush", or the reddening of skin that causes itchiness. Niacinamide has not been found to cause this.
In very rare cases, some individuals may not be able to tolerate niacinamide at all or experience an allergic reaction to it.
If you are experiencing flaking, irritation, and dryness with this ingredient, be sure to double check all your products as this ingredient can be found in all categories of skincare.
When incorporating niacinamide into your routine, look out for concentration amounts. Typically, 5% niacinamide provides benefits such as fading dark spots. However, if you have sensitive skin, it is better to begin with a smaller concentration.
When you apply niacinamide to your skin, your body converts it into nicotinamide adenine dinucleotide (NAD). NAD is an essential coenzyme that is already found in your cells as "fuel" and powers countless biological processes.
In your skin, NAD helps repair cell damage, produce new healthy cells, support collagen production, strengthen the skin barrier, and fight environmental stressors (like UV and pollution).
Our natural NAD levels start to decline with age, leading to slower skin repair, visible aging, and a weaker skin barrier. By providing your skin niacinamide, you're recharging your skin's NAD levels. This leads to stronger, healthier, and younger looking skin.
Another name for vitamin B3 is nicotinamide. This vitamin is water-soluble and our bodies don't store it. We obtain Vitamin B3 from either food or skincare. Meat, fish, wheat, yeast, and leafy greens contain vitamin B3.
The type of niacinamide used in skincare is synthetically created.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!