Skin science article
SKIN1004 Tone Brightening Tone-up Sunscreen SPF50+ PA++++ Versus D'Alba Peptide No Sebum Repair Cream
SKIN1004 Tone Brightening Tone-up Sunscreen SPF50+ PA++++ Versus D'Alba Peptide No Sebum Repair Cream This hybrid sunscreen covers the full UV range and blocks ~98% of UVB at SPF 50. This oil-control moisturizer is formulated around Niacinamide and Acetyl Hexa
SKIN1004 Tone Brightening Tone-up Sunscreen SPF50+ PA++++ Versus D'Alba Peptide No Sebum Repair Cream
This hybrid sunscreen covers the full UV range and blocks ~98% of UVB at SPF 50.
This oil-control moisturizer is formulated around Niacinamide and Acetyl Hexapeptide-8 to balance excess oil and strengthen the skin barrier.
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Dibutyl Adipate
Titanium Dioxide
Propanediol
Caprylic/Capric Triglyceride
Centella Asiatica Extract
C12-15 Alkyl Benzoate
Diethylamino Hydroxybenzoyl Hexyl Benzoate
Ethylhexyl Triazone
Niacinamide
Caprylyl Methicone
Diethylhexyl Butamido Triazone
1,2-Hexanediol
Pentylene Glycol
Corchorus Olitorius Leaf Extract
Hordeum Vulgare Sprout Extract
Nymphaea Alba Flower Extract
Sodium Hyaluronate
Coco-Caprylate/Caprate
Glycerin
Polyhydroxystearic Acid
Dimethicone/Vinyl Dimethicone Crosspolymer
Vp/Eicosene Copolymer
Dimethiconol
Trisiloxane
Stearic Acid
Alumina
Sodium Polyacryloyldimethyl Taurate
Polyacrylate Crosspolymer-6
Hydroxypropyl Methylcellulose Stearoxy Ether
Dicaprylyl Carbonate
Ethylhexylglycerin
Xanthan Gum
Triethoxycaprylylsilane
Adenosine
Sodium Polyacrylate
Madecassoside
Pvm/Ma Copolymer
Polyether-1
T-Butyl Alcohol
Tranexamic Acid
Dipropylene Glycol
Sodium Palmitoyl Proline
Butylene Glycol
CI 77492
CI 77491
Water, Dibutyl Adipate, Titanium Dioxide, Propanediol, Caprylic/Capric Triglyceride, Centella Asiatica Extract, C12-15 Alkyl Benzoate, Diethylamino Hydroxybenzoyl Hexyl Benzoate, Ethylhexyl Triazone, Niacinamide, Caprylyl Methicone, Diethylhexyl Butamido Triazone, 1,2-Hexanediol, Pentylene Glycol, Corchorus Olitorius Leaf Extract, Hordeum Vulgare Sprout Extract, Nymphaea Alba Flower Extract, Sodium Hyaluronate, Coco-Caprylate/Caprate, Glycerin, Polyhydroxystearic Acid, Dimethicone/Vinyl Dimethicone Crosspolymer, Vp/Eicosene Copolymer, Dimethiconol, Trisiloxane, Stearic Acid, Alumina, Sodium Polyacryloyldimethyl Taurate, Polyacrylate Crosspolymer-6, Hydroxypropyl Methylcellulose Stearoxy Ether, Dicaprylyl Carbonate, Ethylhexylglycerin, Xanthan Gum, Triethoxycaprylylsilane, Adenosine, Sodium Polyacrylate, Madecassoside, Pvm/Ma Copolymer, Polyether-1, T-Butyl Alcohol, Tranexamic Acid, Dipropylene Glycol, Sodium Palmitoyl Proline, Butylene Glycol, CI 77492, CI 77491
Squalane
Cetearyl Olivate
Sorbitan Olivate
Dimethicone
Cetearyl Alcohol
Cetearyl Glucoside
Carbomer
Hydroxypropyl Methylcellulose
Artemisia Annua Extract
Nelumbo Nucifera Flower Extract
Oryza Sativa Extract
Saccharomyces Ferment
Arginine
Octyldodecanol
Panthenol
Melaleuca Alternifolia Leaf Extract
Helianthus Annuus Seed Oil
Lavandula Angustifolia Oil
Pullulan
Tuber Magnatum Extract
Calamine
Dipotassium Glycyrrhizate
Tocopheryl Acetate
Hydrogenated Lecithin
Ceramide NP
Polygonum Cuspidatum Root Extract
Scutellaria Baicalensis Root Extract
Biosaccharide Gum-1
Alkanna Tinctoria Root Extract
Caprylyl Glycol
Betaine Salicylate
Camellia Sinensis Leaf Extract
Glycyrrhiza Glabra Root Extract
Chamomilla Recutita Flower Extract
Porphyridium Cruentum Extract
Rosmarinus Officinalis Leaf Extract
Glucose
Sodium Hyaluronate Crosspolymer
Acetyl Hexapeptide-8
Hydrolyzed Hyaluronic Acid
Hyaluronic Acid
Tocopherol
Hydrolyzed Sodium Hyaluronate
Water, Butylene Glycol, Glycerin, Caprylic/Capric Triglyceride, Squalane, 1,2-Hexanediol, Niacinamide, Cetearyl Olivate, Sorbitan Olivate, Dimethicone, Cetearyl Alcohol, Cetearyl Glucoside, Carbomer, Hydroxypropyl Methylcellulose, Artemisia Annua Extract, Nelumbo Nucifera Flower Extract, Oryza Sativa Extract, Saccharomyces Ferment, Arginine, Octyldodecanol, Panthenol, Melaleuca Alternifolia Leaf Extract, Helianthus Annuus Seed Oil, Lavandula Angustifolia Oil, Pullulan, Tuber Magnatum Extract, Calamine, Centella Asiatica Extract, Dipotassium Glycyrrhizate, Tocopheryl Acetate, Ethylhexylglycerin, Adenosine, Sodium Hyaluronate, Hydrogenated Lecithin, Pentylene Glycol, Ceramide NP, Polygonum Cuspidatum Root Extract, Scutellaria Baicalensis Root Extract, Biosaccharide Gum-1, Alkanna Tinctoria Root Extract, Caprylyl Glycol, Betaine Salicylate, Camellia Sinensis Leaf Extract, Glycyrrhiza Glabra Root Extract, Chamomilla Recutita Flower Extract, Porphyridium Cruentum Extract, Rosmarinus Officinalis Leaf Extract, Glucose, Sodium Hyaluronate Crosspolymer, Acetyl Hexapeptide-8, Hydrolyzed Hyaluronic Acid, Hyaluronic Acid, Tocopherol, Hydrolyzed Sodium Hyaluronate
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Alternatives
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse.
It is a:
Humectant, drawing moisture into the skin
Emollient, helping to soften skin
Solvent, dispersing and stabilizing formulas
Preservative booster, enhancing the antimicrobial activity of other preservatives
Adenosine is a purine nucleoside that your body already makes in every cell. In skincare, it acts mainly as a skin conditioning and anti-aging agent.
The way it works is fairly well mapped out:
Your skin has cells called fibroblasts that build collagen (the stuff that keeps skin firm and smooth). Adenosine basically flips a switch on these cells that tells them to get to work making more collagen and other proteins. These cells slow down on their own as skin ages, so Adenosine helps give them a little nudge to keep going.
The clinical backing is pretty solid too.
A blind, randomized, placebo-controlled trial of 126 women aged 45-65 tested a 0.1% cream twice daily and found real improvements in crow's feet and frown lines using a precise 3D skin-mapping technique; these changes showed up by week 3 and held at 2 months.
A later study using Adenosine-loaded dissolving microneedle patches reported gains in wrinkle depth, dermal density, elasticity, and hydration.
On concentrations, South Korea's Ministry of Food and Drug Safety has set 0.04% as the approved functional anti-wrinkle level. You'll typically see this ingredient used somewhere in the 0.04-0.1% range since it works at low doses.
This ingredient has been found safe for cosmetics with the data showing no irritation or sensitization.
Overall, this is a great ingredient for any anti-aging routine and has no photosensitizing effect, so it suits both AM and PM use.
Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:
Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.
Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.
Caprylic/Capric Triglyceride (aka MCT Oil) is a lightweight emollient, solvent, and texture enhancer. It is considered a skin-softener by helping to prevent moisture loss.
Though it behaves like an oil, it is not technically one due to its chemical composition. One perk of this ingredient is that it is very stable, resistant to oxidation, and unlikely to go rancid.
In practice, that translates to a long shelf life and a consistently elegant skin feel.
While there is an assumption Caprylic Triglyceride can clog pores due to it being derived from coconut oil, there is no research supporting this. Just patch test if you have concerns.
Fractionated coconut oil and MCT Oil are both listed as Caprylic/Capric Triglyceride according to INCI. This is because INCI names are based on the ingredient’s final chemical composition and not its marketing name or source.
This ingredient is treated as the gold standard fungal acne safe oil. Even though it is coconut derived, the problematic lauric acid is stripped out.
This leaves just caprylic (C8) and capric (C10) acid. These chain lengths actually trend antifungal; a 2020 study found caprylic acid was enough to disrupt Malassezia furfur cell membrane, with a caprylic acid derivative damaging membrane structures at concentrations as low as 0.2%.
Centella Asiatica Extract (Centella) is one of the most researched botanical extracts in skincare with decades of studies backing its effects on inflammation, collagen, and the skin barrier.
That research keeps pointing back to the same four triterpenoid saponins: Asiaticoside, Madecassoside, Asiatic Acid, and Madecassic Acid.
These compounds allow centella to dial back inflammation, encourage the skin to build and hold onto collagen, support the barrier and hydration, and bring solid antioxidant activity to protect against signs of aging.
Centella also carries a nice supporting cast of Vitamin A, vitamin C, several B vitamins, and amino acids. Put it all together and you get an ingredient that soothes, hydrates, and protects, all at once.
Most of centella's magic comes from the four big compounds (Asiaticoside, Madecassoside, Asiatic Acid, and Madecassic Acid). These are the actives doing the heavy lifting in almost every centella study.
Here is the short version of what they do in the skin:
So it is not just soothing for the sake of soothing. Centella calms the skin AND helps it rebuild.
Just FYI, not all centella on an ingredient list is the same. What you are getting actually depends on the extract:
Fun fact on the ratios: the leaves tend to be richest in Madecassoside and Asiaticoside, and lower in the two acids. The exact amounts shift with where the plant is grown and how it is processed. This means purity really does vary brand to brand.
Centella is one of the most easygoing actives out there.
It layers well with basically everything: niacinamide, hyaluronic acid, peptides, and vitamin C, and also pairs nicely with stronger actives like retinoids and exfoliating acids where it can help take the edge off irritation.
On the safety side, centella and its triterpenes are classified as weak sensitizers, meaning allergic reactions are possible but uncommon.
Patch tests at 1% and 5% came back negative in test panels, and creams at typical use levels did not cause allergic reactions across large groups of people.
But as with any new active, a patch test is still a smart move for very reactive skin.
Centella is widely used because it is effective at low percentages. For context, human safety testing found no meaningful irritation from creams containing centella extract at everyday use levels (the tested amounts were well under 1%).
The irritancy threshold in animal testing was also above 30% (so real-world formulas sit far below anything concerning).
In collagen lab studies, higher concentrations drove more collagen synthesis, so serums built around centella tend to feature it more prominently.
Bottom line: you will find centella working nicely anywhere from a fraction of a percent up to hero-ingredient levels depending on whether it is a supporting soother or the main event.
Fun fact: Centella has been used as a medicine and in food for many centuries. As a medicine, it is used to treat burns, scratches, and wounds.
Ethylhexylglycerin is created from glycerin. It is a multitasker ingredient that:
The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.
Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.
Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Niacinamide is a multitasking form of vitamin B3 that strengthens the skin barrier, reduces pores and dark spots, regulates oil, and improves signs of aging.
And the best part? It's gentle and well-tolerated by most skin types, including sensitive and reactive skin.
You might have heard of "niacin flush", or the reddening of skin that causes itchiness. Niacinamide has not been found to cause this.
In very rare cases, some individuals may not be able to tolerate niacinamide at all or experience an allergic reaction to it.
If you are experiencing flaking, irritation, and dryness with this ingredient, be sure to double check all your products as this ingredient can be found in all categories of skincare.
When incorporating niacinamide into your routine, look out for concentration amounts. Typically, 5% niacinamide provides benefits such as fading dark spots. However, if you have sensitive skin, it is better to begin with a smaller concentration.
When you apply niacinamide to your skin, your body converts it into nicotinamide adenine dinucleotide (NAD). NAD is an essential coenzyme that is already found in your cells as "fuel" and powers countless biological processes.
In your skin, NAD helps repair cell damage, produce new healthy cells, support collagen production, strengthen the skin barrier, and fight environmental stressors (like UV and pollution).
Our natural NAD levels start to decline with age, leading to slower skin repair, visible aging, and a weaker skin barrier. By providing your skin niacinamide, you're recharging your skin's NAD levels. This leads to stronger, healthier, and younger looking skin.
Another name for vitamin B3 is nicotinamide. This vitamin is water-soluble and our bodies don't store it. We obtain Vitamin B3 from either food or skincare. Meat, fish, wheat, yeast, and leafy greens contain vitamin B3.
The type of niacinamide used in skincare is synthetically created.
Pentylene Glycol (1,2-pentanediol) is a multitasking little diol with three main roles in a formula:
Research on alkanediols (the family pentylene glycol belongs to) show they work by disrupting microbial cell membranes. This disruption helps the primary preservative system in a product work more effectively at lower doses.
On the safety side, the Cosmetic Ingredient Review Expert Panel has concluded this ingredient to be safe as used in current cosmetic practices + concentrations.
Typical use levels in a formula run about 1-5%.
Sodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity.
In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface.
Interestingly, the size of the molecule affects its behavior:
Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.
Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.
You'll typically see concentrations between 0.1-2% for this ingredient.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!