Naturium Multi-Peptide Advanced Serum Versus Eqqualberry Bakuchiol Plumping Serum

Naturium Multi-Peptide Advanced Serum Versus Eqqualberry Bakuchiol Plumping Serum

This anti-aging serum is formulated around Acetyl Hexapeptide-8 and Ferulic Acid to soften the look of wrinkles.

This anti-aging serum is formulated around Bakuchiol and Niacinamide to soften the look of wrinkles and strengthen the skin barrier.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Propanediol

Caprylic/Capric Triglyceride

Isopentyldiol

Ethylhexyl Polyhydroxystearate

Squalane

Tetradecane

Glyceryl Stearate Citrate

Butyrospermum Parkii Butter

Polyglyceryl-3 Stearate

Helianthus Annuus Extract

Oryza Sativa Bran Extract

Mannitol

Phosphatidylcholine

Ferulic Acid

Arginine

Acetyl Hexapeptide-8

Copper Palmitoyl Heptapeptide-14

Palmitoyl Sh-Heptapeptide-12 Sp

Hydrolyzed Collagen

Rosmarinus Officinalis Leaf Extract

Lactic Acid/Glycolic Acid Copolymer

Glycerin

Tocopherol

Pullulan

Lysolecithin

Sclerotium Gum

Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer

Dimethicone

Sodium Phytate

Diglycerin

Hydrogenated Lecithin

Silica

Cetyl Alcohol

Hydroxyacetophenone

Polysorbate 60

Sorbitan Isostearate

Sodium Hydroxide

Sodium Benzoate

Potassium Sorbate

Polyvinyl Alcohol

Decyl Glucoside

Xanthan Gum

Tocopheryl Acetate

Sodium Chloride

Citric Acid

Phenoxyethanol

Water, Propanediol, Caprylic/Capric Triglyceride, Isopentyldiol, Ethylhexyl Polyhydroxystearate, Squalane, Tetradecane, Glyceryl Stearate Citrate, Butyrospermum Parkii Butter, Polyglyceryl-3 Stearate, Helianthus Annuus Extract, Oryza Sativa Bran Extract, Mannitol, Phosphatidylcholine, Ferulic Acid, Arginine, Acetyl Hexapeptide-8, Copper Palmitoyl Heptapeptide-14, Palmitoyl Sh-Heptapeptide-12 Sp, Hydrolyzed Collagen, Rosmarinus Officinalis Leaf Extract, Lactic Acid/Glycolic Acid Copolymer, Glycerin, Tocopherol, Pullulan, Lysolecithin, Sclerotium Gum, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Dimethicone, Sodium Phytate, Diglycerin, Hydrogenated Lecithin, Silica, Cetyl Alcohol, Hydroxyacetophenone, Polysorbate 60, Sorbitan Isostearate, Sodium Hydroxide, Sodium Benzoate, Potassium Sorbate, Polyvinyl Alcohol, Decyl Glucoside, Xanthan Gum, Tocopheryl Acetate, Sodium Chloride, Citric Acid, Phenoxyethanol

Butylene Glycol

Cetyl Ethylhexanoate

1,2-Hexanediol

Niacinamide

Pentaerythrityl Tetrabehenate

Diethoxyethyl Succinate

Betaine

Ceramide NP

Melia Azadirachta Flower Extract

Hydroxyethyl Urea

Bakuchiol

Cetearyl Alcohol

Coccinia Indica Fruit Extract

Panthenol

Carbomer

Tromethamine

Allantoin

Ethylhexylglycerin

2,3-Butanediol

Adenosine

Disodium EDTA

Lavandula Angustifolia Oil

Sodium Carboxymethyl Beta-Glucan

Glyceryl Stearate

Dipropylene Glycol

Citrus Aurantium Bergamia Fruit Oil

Sodium Hyaluronate

Rubus Fruticosus Fruit Extract

Vaccinium Macrocarpon Fruit Extract

Vaccinium Angustifolium Fruit Extract

Rubus Idaeus Fruit Extract

Sambucus Nigra Fruit Extract

Sodium Lactate

Polyglyceryl-10 Laurate

Ceramide Ns

Ceramide As

Ceramide AP

Cholesterol

Salvia Officinalis Oil

Polysorbate 20

Octyldodecanol

Polyglyceryl-4 Caprate

Methylpropanediol

Hydrolyzed Hyaluronic Acid

Hydrolyzed Sodium Hyaluronate

Hyaluronic Acid

Hydroxypropyltrimonium Hyaluronate

Potassium Hyaluronate

Astaxanthin

Pentylene Glycol

Sodium Hyaluronate Crosspolymer

Palmitoyl Tripeptide-1

Soluble Collagen

Sodium Acetylated Hyaluronate

Copper Tripeptide-1

Palmitoyl Tetrapeptide-7

Oligopeptide-32

Oligopeptide-29

Ceramide EOP

Acetyl Tetrapeptide-2

Acetyl Tetrapeptide-3

Acetyl Octapeptide-3

Palmitoyl Pentapeptide-4

Oligopeptide-6

Hexapeptide-9

Nonapeptide-1

Limonene

Linalool

Water, Butylene Glycol, Glycerin, Cetyl Ethylhexanoate, 1,2-Hexanediol, Niacinamide, Hydrogenated Lecithin, Pentaerythrityl Tetrabehenate, Diethoxyethyl Succinate, Betaine, Ceramide NP, Melia Azadirachta Flower Extract, Hydroxyethyl Urea, Bakuchiol, Cetearyl Alcohol, Squalane, Coccinia Indica Fruit Extract, Panthenol, Carbomer, Butyrospermum Parkii Butter, Tromethamine, Xanthan Gum, Allantoin, Ethylhexylglycerin, 2,3-Butanediol, Adenosine, Disodium EDTA, Lavandula Angustifolia Oil, Sodium Carboxymethyl Beta-Glucan, Glyceryl Stearate, Dipropylene Glycol, Citrus Aurantium Bergamia Fruit Oil, Sodium Hyaluronate, Rubus Fruticosus Fruit Extract, Vaccinium Macrocarpon Fruit Extract, Vaccinium Angustifolium Fruit Extract, Rubus Idaeus Fruit Extract, Sambucus Nigra Fruit Extract, Sodium Lactate, Polyglyceryl-10 Laurate, Ceramide Ns, Ceramide As, Ceramide AP, Cholesterol, Salvia Officinalis Oil, Polysorbate 20, Octyldodecanol, Polyglyceryl-4 Caprate, Methylpropanediol, Hydrolyzed Hyaluronic Acid, Hydrolyzed Sodium Hyaluronate, Hyaluronic Acid, Hydroxypropyltrimonium Hyaluronate, Potassium Hyaluronate, Astaxanthin, Pentylene Glycol, Sodium Hyaluronate Crosspolymer, Palmitoyl Tripeptide-1, Soluble Collagen, Sodium Acetylated Hyaluronate, Copper Tripeptide-1, Palmitoyl Tetrapeptide-7, Oligopeptide-32, Oligopeptide-29, Acetyl Hexapeptide-8, Ceramide EOP, Acetyl Tetrapeptide-2, Acetyl Tetrapeptide-3, Acetyl Octapeptide-3, Palmitoyl Pentapeptide-4, Oligopeptide-6, Hexapeptide-9, Nonapeptide-1, Limonene, Linalool

Reviews

Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Acetyl Hexapeptide-8 (also known as Argireline) is a synthetic hexapeptide that is often called a "topical Botox alternative".

It works by mimicking how Botox relaxes muscles; it interferes with the signaling process that tells your facial muscles to contract. This can help soften expression lines like forehead wrinkles or crow's feet over time.

The comparison to Botox does have limits because the molecule is water-loving and relatively large.

Acetyl Hexapeptide-8 has a hard time absorbing deeply enough through the skin's outer barrier to actually reach the muscles.

So whether it truly works the way Botox does at a biological level is still up for debate, but early clinical outcomes are fairly encouraging.

A 12 week human study of a multi-ingredient regimen containing this ingredient saw:

While some studies have observed improvements in wrinkle appearance, it is important to note that more consistent results are seen in multi-ingredient formulations (vs just Acetyl Hexapeptide-8 alone).

Some research studies also used higher concentrations (up to 10%) while this ingredient is usually found in concentrations up to 0.005% in leave-on formulations.

This ingredient is also known as shea butter. It is a plant-derived extract from the nuts of the Africa shea tree and one of the most well-studied emollients.

Because it has a high concentration of fatty acids (primarily oleic, stearic, and linoleic) it is able to form a protective barrier on the skin's surface. This helps seal in moisture and prevents transepidermal water loss (TEWL).

In vitro research found an increase in skin hydration by 58% and a decrease in TEWL by 37.8% after 24 hours of applying this ingredient (pretty impressive for a single ingredient!).

Besides hydration, shea butter also contains triterpenes that have anti-inflammatory potential. In particule, lupeol cinnamate has shown the highest anti-inflammatory activity in vivo.

Shea butter also contains vitamins A and E which may contribute to antioxidant activity.

While Shea Butter has an SPF rating of about 3-4, it is not a sunscreen replacement.

This ingredient may not be fungal acne safe because its fatty acids fall within the C11-C24 range that the Malassezia yeast can metabolize.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Hydrogenated Lecithin is a more stable version of lecithin.

It's made by taking lecithin (a phospholipid commonly found in soybeans and egg yolks) and hydrogenating it. This just means the unsaturated fatty acids are turned into saturated ones so they don't go bad as easily.

This ingredient is an emollient, emulsifier, and penetration enhancer. As an emollient, it helps soften and hydrate skin by trapping moisture within. As an emulsifier, it prevents oil and water ingredients from separating.

Hydrogenated Lecithin can form tiny spherical structures made of phospholipid bilayers called liposomes. These liposomes are able to capture compounds inside their structure and deliver them through the skin barrier.

Because phospholipids are a natural component of our cell membranes, this ingredient is inherently compatible with skin.

A 2021 study found lecithin-based surfactants were less harsh and more tolerable comared to Sodium Lauryl Sulfate (SLS).

Squalane is the hydrogenated and shelf-stable form of squalene (a lipid that naturally occurs in human sebum).

It is an emollient and skin conditioning agent that is able to integrate seamlessly into the skin's lipid barrier without clogging pores.

This is due to how structurally similar it is to what your skin already produces.

Though it is mostly an emollient that helps soften and hydrate skin, it also has some humectant and occlusive action. Humectants help the skin retain moisture while occlusives seal it in, making squalane a triple-threat moisturizer.

Research shows it has antioxidant capabilities that help protect against stressors like UV exposure, specifically UVA induced oxidative stress. This study also found that it supports collagen biosynthesis in human dermal fibroblasts.

No clinical study has reported significant adverse effects and irritation reactions are very rare from this ingredient (even at 100% concentration).

Overall, it's a fantastic ingredient for hydration and is suitable for all skin types.

This depends on the source. Squalane can be derived from both plants and animals. Most squalane used in skincare comes from plants.

Please note: the source of squalane is only known if disclosed by the brand. We recommend reaching out to the brand if you have any questions about their squalane.

Read more about squalene with an "e".

Though squalane is often called an oil, it’s technically not one. It is a hydrocarbon, meaning it is only made of carbon and hydrogen. True oils are triglycerides and made of fatty acids and glycerol.

The term “oil-free” isn’t regulated so companies can define it however they want. Some exclude all oils, while others just avoid mineral oil or comedogenic oils.

Squalane has a comedogenic rating of 1 from the original 1972 study that tested raw ingredients under occlusion on rabbit ears. This system is not standardized or peer-reviewed, and using the raw ingredients is very different from how diluted cosmetic formulations are used on human skin.

A comedogenic rating of 1 means it is "unlikely to clog pores" according to the original rating system.

The overall formula of a product matters more than the individual ingredients on whether or not it will cause clogged pores.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.

On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.

Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.

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