Skin science article
Naturium Multi-Peptide Advanced Serum Versus PURITO Centella Unscented Serum
Naturium Multi-Peptide Advanced Serum Versus PURITO Centella Unscented Serum This anti-aging serum is formulated around Acetyl Hexapeptide-8 and Ferulic Acid to soften the look of wrinkles. This calming serum is formulated around Centella Asiatica Extract and
Naturium Multi-Peptide Advanced Serum Versus PURITO Centella Unscented Serum
This anti-aging serum is formulated around Acetyl Hexapeptide-8 and Ferulic Acid to soften the look of wrinkles.
This calming serum is formulated around Centella Asiatica Extract and Niacinamide to calm redness and strengthen the skin barrier.
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Propanediol
Caprylic/Capric Triglyceride
Isopentyldiol
Ethylhexyl Polyhydroxystearate
Squalane
Tetradecane
Glyceryl Stearate Citrate
Butyrospermum Parkii Butter
Polyglyceryl-3 Stearate
Helianthus Annuus Extract
Oryza Sativa Bran Extract
Mannitol
Phosphatidylcholine
Ferulic Acid
Arginine
Acetyl Hexapeptide-8
Copper Palmitoyl Heptapeptide-14
Palmitoyl Sh-Heptapeptide-12 Sp
Hydrolyzed Collagen
Rosmarinus Officinalis Leaf Extract
Lactic Acid/Glycolic Acid Copolymer
Glycerin
Tocopherol
Pullulan
Lysolecithin
Sclerotium Gum
Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer
Dimethicone
Sodium Phytate
Diglycerin
Hydrogenated Lecithin
Silica
Cetyl Alcohol
Hydroxyacetophenone
Polysorbate 60
Sorbitan Isostearate
Sodium Hydroxide
Sodium Benzoate
Potassium Sorbate
Polyvinyl Alcohol
Decyl Glucoside
Xanthan Gum
Tocopheryl Acetate
Sodium Chloride
Citric Acid
Phenoxyethanol
Water, Propanediol, Caprylic/Capric Triglyceride, Isopentyldiol, Ethylhexyl Polyhydroxystearate, Squalane, Tetradecane, Glyceryl Stearate Citrate, Butyrospermum Parkii Butter, Polyglyceryl-3 Stearate, Helianthus Annuus Extract, Oryza Sativa Bran Extract, Mannitol, Phosphatidylcholine, Ferulic Acid, Arginine, Acetyl Hexapeptide-8, Copper Palmitoyl Heptapeptide-14, Palmitoyl Sh-Heptapeptide-12 Sp, Hydrolyzed Collagen, Rosmarinus Officinalis Leaf Extract, Lactic Acid/Glycolic Acid Copolymer, Glycerin, Tocopherol, Pullulan, Lysolecithin, Sclerotium Gum, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Dimethicone, Sodium Phytate, Diglycerin, Hydrogenated Lecithin, Silica, Cetyl Alcohol, Hydroxyacetophenone, Polysorbate 60, Sorbitan Isostearate, Sodium Hydroxide, Sodium Benzoate, Potassium Sorbate, Polyvinyl Alcohol, Decyl Glucoside, Xanthan Gum, Tocopheryl Acetate, Sodium Chloride, Citric Acid, Phenoxyethanol
Centella Asiatica Extract 49%
Dipropylene Glycol
Niacinamide
Butylene Glycol
1,2-Hexanediol
Glycereth-26
Ceramide NP
Sodium Hyaluronate
Asiaticoside
Asiatic Acid
Madecassic Acid
Palmitoyl Hexapeptide-12
Palmitoyl Tripeptide-1
Palmitoyl Tetrapeptide-7
Palmitoyl Dipeptide-10
Carbomer
Hydrolyzed Jojoba Esters
Caprylyl Glycol
Polyglyceryl-10 Myristate
Panthenol
Polyglyceryl-10 Laurate
Camellia Sinensis Leaf Extract
Pancratium Maritimum Extract
Dipotassium Glycyrrhizate
Disodium EDTA
Adenosine
Centella Asiatica Extract 49%, Water, Glycerin, Dipropylene Glycol, Niacinamide, Butylene Glycol, 1,2-Hexanediol, Glycereth-26, Ceramide NP, Sodium Hyaluronate, Asiaticoside, Asiatic Acid, Madecassic Acid, Palmitoyl Hexapeptide-12, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Palmitoyl Dipeptide-10, Carbomer, Arginine, Sclerotium Gum, Hydrolyzed Jojoba Esters, Caprylyl Glycol, Polyglyceryl-10 Myristate, Panthenol, Polyglyceryl-10 Laurate, Hydrogenated Lecithin, Camellia Sinensis Leaf Extract, Pancratium Maritimum Extract, Dipotassium Glycyrrhizate, Disodium EDTA, Adenosine
Reviews
Alternatives
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Arginine is a semi-essential amino acid. This just means our bodies can product a bit on its own, but sometimes needs a little boost from food sources.
It is a part of your skin's natural moisturizing factor (NMF), or the water-loving molecules in your outermost layer of skin (stratum corneum) that keeps everything hydrated and happy.
Here's an interesting thing about Arginine: your skin converts it into urea through the Krebs-Henseleit urea cycle. Urea is one of the most effective humectants your skin naturally produces.
A clinical study showed applying 2.5% arginine hydrochloride to atopic dermatitis skin showed significant urea levels in the stratum corneum and improved moisture in just four weeks.
Arginine is also a precursor to nitric oxide; nitric oxide improves microcirculation and supports wound healing and collagen synthesis.
One study found that an amino acid complex containing Arginine reduced skin irritation, improved hydration, and accelerated skin repair in clinical / in-vivo studies.
Arginine itself is an amino acid and not a fatty acid, oil, or ester. On its own, it's not a direct food source for Malassezia, or the yeast that causes fungal acne.
Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Hydrogenated Lecithin is a more stable version of lecithin.
It's made by taking lecithin (a phospholipid commonly found in soybeans and egg yolks) and hydrogenating it. This just means the unsaturated fatty acids are turned into saturated ones so they don't go bad as easily.
This ingredient is an emollient, emulsifier, and penetration enhancer. As an emollient, it helps soften and hydrate skin by trapping moisture within. As an emulsifier, it prevents oil and water ingredients from separating.
Hydrogenated Lecithin can form tiny spherical structures made of phospholipid bilayers called liposomes. These liposomes are able to capture compounds inside their structure and deliver them through the skin barrier.
Because phospholipids are a natural component of our cell membranes, this ingredient is inherently compatible with skin.
A 2021 study found lecithin-based surfactants were less harsh and more tolerable comared to Sodium Lauryl Sulfate (SLS).
Sclerotium Gum is a natural sugar-based fiber made by fermenting a fungus called Sclerotium rolfsii. It's often used as the plant-friendly alternative for synthetic thickeners like carbomer.
In skincare, it works as a thickener, gel former, and stabilizer that keeps heavy ingredients suspended so a product does not separate.
It is non-ionic and forms a triple helix in solution. This is just a fancy way of saying it builds a smooth, cushiony, and non-sticky gel that feels silkier than many other gums.
Another perk of this ingredient is that it is very sturdy and holds up across a wide pH range (~2-11). It's also good at resisting heat and hydrolysis.
Since it holds water at the skin surface, it can provide some light hydration as well.
Typical use levels are around 0.25-2%; formulators usually use 0.2-0.5% to thicken lotions and up to 2% for a firmer gel base.
This ingredient has been found safe in cosmetics with no meaningful evidence of skin sensitization.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!