Skin science article
Naturium Multi-Peptide Advanced Serum Versus The Ordinary Matrixyl 10% + HA
Naturium Multi-Peptide Advanced Serum Versus The Ordinary Matrixyl 10% + HA This anti-aging serum is formulated around Acetyl Hexapeptide-8 and Ferulic Acid to soften the look of wrinkles. This anti-aging serum is formulated around Palmitoyl Tripeptide-1 and P
Naturium Multi-Peptide Advanced Serum Versus The Ordinary Matrixyl 10% + HA
This anti-aging serum is formulated around Acetyl Hexapeptide-8 and Ferulic Acid to soften the look of wrinkles.
This anti-aging serum is formulated around Palmitoyl Tripeptide-1 and Palmitoyl Tetrapeptide-7 to soften the look of wrinkles and refine skin texture.
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Propanediol
Caprylic/Capric Triglyceride
Isopentyldiol
Ethylhexyl Polyhydroxystearate
Squalane
Tetradecane
Glyceryl Stearate Citrate
Butyrospermum Parkii Butter
Polyglyceryl-3 Stearate
Helianthus Annuus Extract
Oryza Sativa Bran Extract
Mannitol
Phosphatidylcholine
Ferulic Acid
Arginine
Acetyl Hexapeptide-8
Copper Palmitoyl Heptapeptide-14
Palmitoyl Sh-Heptapeptide-12 Sp
Hydrolyzed Collagen
Rosmarinus Officinalis Leaf Extract
Lactic Acid/Glycolic Acid Copolymer
Glycerin
Tocopherol
Pullulan
Lysolecithin
Sclerotium Gum
Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer
Dimethicone
Sodium Phytate
Diglycerin
Hydrogenated Lecithin
Silica
Cetyl Alcohol
Hydroxyacetophenone
Polysorbate 60
Sorbitan Isostearate
Sodium Hydroxide
Sodium Benzoate
Potassium Sorbate
Polyvinyl Alcohol
Decyl Glucoside
Xanthan Gum
Tocopheryl Acetate
Sodium Chloride
Citric Acid
Phenoxyethanol
Water, Propanediol, Caprylic/Capric Triglyceride, Isopentyldiol, Ethylhexyl Polyhydroxystearate, Squalane, Tetradecane, Glyceryl Stearate Citrate, Butyrospermum Parkii Butter, Polyglyceryl-3 Stearate, Helianthus Annuus Extract, Oryza Sativa Bran Extract, Mannitol, Phosphatidylcholine, Ferulic Acid, Arginine, Acetyl Hexapeptide-8, Copper Palmitoyl Heptapeptide-14, Palmitoyl Sh-Heptapeptide-12 Sp, Hydrolyzed Collagen, Rosmarinus Officinalis Leaf Extract, Lactic Acid/Glycolic Acid Copolymer, Glycerin, Tocopherol, Pullulan, Lysolecithin, Sclerotium Gum, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Dimethicone, Sodium Phytate, Diglycerin, Hydrogenated Lecithin, Silica, Cetyl Alcohol, Hydroxyacetophenone, Polysorbate 60, Sorbitan Isostearate, Sodium Hydroxide, Sodium Benzoate, Potassium Sorbate, Polyvinyl Alcohol, Decyl Glucoside, Xanthan Gum, Tocopheryl Acetate, Sodium Chloride, Citric Acid, Phenoxyethanol
Butylene Glycol
Palmitoyl Tripeptide-1
Palmitoyl Tetrapeptide-7
Palmitoyl Tripeptide-38
Sodium Hyaluronate
Hydroxypropyl Cyclodextrin
PPG-26-Buteth-26
PEG-40 Hydrogenated Castor Oil
Polyacrylate Crosspolymer-6
Trisodium Ethylenediamine Disuccinate
Carbomer
Polysorbate 20
Ethoxydiglycol
Chlorphenesin
Water, Glycerin, Butylene Glycol, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Palmitoyl Tripeptide-38, Sodium Hyaluronate, Hydroxypropyl Cyclodextrin, PPG-26-Buteth-26, PEG-40 Hydrogenated Castor Oil, Polyacrylate Crosspolymer-6, Trisodium Ethylenediamine Disuccinate, Carbomer, Polysorbate 20, Ethoxydiglycol, Phenoxyethanol, Chlorphenesin
Reviews
Alternatives
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).
It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.
On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.
Another perk of this ingredient is that it stays functional across a wide pH range (3-10).
You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.
Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.
Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.
Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!