Perricone MD High Potency Growth Factor Firming & Lifting Serum Versus SkinMedica TNS® Advanced+ Serum

Perricone MD High Potency Growth Factor Firming & Lifting Serum Versus SkinMedica TNS® Advanced+ Serum

This anti-aging serum is formulated around Niacinamide and Retinol to soften the look of wrinkles and refine skin texture.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Butylene Glycol

Heptyl Undecylenate

Lecithin

Alcohol Denat.

Polymethyl Methacrylate

Niacinamide

Pentaerythrityl Adipate/Caprate/Caprylate/Heptanoate

Phosphatidylcholine

Ascorbyl Palmitate

Hydrolyzed Egg Shell Membrane

Tricaprylin

Retinol

Tocopherol

BHT

Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer

Dipropylene Glycol

Acrylates/C10-30 Alkyl Acrylate Crosspolymer

Cetearyl Alcohol

Stearic Acid

Caprylyl Glycol

Glyceryl Stearate

PEG-100 Stearate

Spermidine

Sodium Polyacrylate

Phenoxyethanol

Parfum

Limonene

Linalool

Hydroxycitronellal

Citronellol

Benzyl Alcohol

Geraniol

Water, Butylene Glycol, Heptyl Undecylenate, Lecithin, Alcohol Denat., Polymethyl Methacrylate, Niacinamide, Pentaerythrityl Adipate/Caprate/Caprylate/Heptanoate, Phosphatidylcholine, Ascorbyl Palmitate, Hydrolyzed Egg Shell Membrane, Tricaprylin, Retinol, Tocopherol, BHT, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Dipropylene Glycol, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Cetearyl Alcohol, Stearic Acid, Caprylyl Glycol, Glyceryl Stearate, PEG-100 Stearate, Spermidine, Sodium Polyacrylate, Phenoxyethanol, Parfum, Limonene, Linalool, Hydroxycitronellal, Citronellol, Benzyl Alcohol, Geraniol

Pentylene Glycol

Human Neonatal Fibroblast Conditioned Media

Glycereth-7 Triacetate

Shea Butter Ethyl Esters

Glycerin

Ethoxydiglycol

Lactococcus Ferment Lysate

Whey Protein

Chlorella Vulgaris Extract

Saccharide Isomerate

Dimer Tripeptide-43

Vitis Vinifera Flower Cell Extract

Pyrus Malus Fruit Extract

Hydroxyacetophenone

Tocopheryl Acetate

Propanediol

Xanthan Gum

Polyacrylate Crosspolymer-6

Polyacrylate-13

Polyisobutene

Sclerotium Gum

PEG-12 Dimethicone

Pullulan

Sodium Citrate

Polysorbate 20

Aminomethyl Propanol

Disodium EDTA

Ethylhexylglycerin

Water, Pentylene Glycol, Human Neonatal Fibroblast Conditioned Media, Glycereth-7 Triacetate, Shea Butter Ethyl Esters, Glycerin, Ethoxydiglycol, Lactococcus Ferment Lysate, Whey Protein, Chlorella Vulgaris Extract, Saccharide Isomerate, Dimer Tripeptide-43, Vitis Vinifera Flower Cell Extract, Pyrus Malus Fruit Extract, Hydroxyacetophenone, Tocopheryl Acetate, Propanediol, Xanthan Gum, Polyacrylate Crosspolymer-6, Polyacrylate-13, Polyisobutene, Sclerotium Gum, PEG-12 Dimethicone, Lecithin, Pullulan, Butylene Glycol, Sodium Citrate, Polysorbate 20, Aminomethyl Propanol, Disodium EDTA, Phenoxyethanol, Ethylhexylglycerin

Reviews

Be the first to review

Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.

Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.

Lecithin is a term for a group of substances found in the cell membranes of plants, animals, and humans. They are made up of phospholipids.

Thanks to its amphiphilic structure (water-loving head and oil-loving tail), it is a true multitasker:

It plays well with most ingredients and is typically used at 0.1-1%. However, concentrations up to 50% have been reported in moisturizers.

Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).

It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.

On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.

Another perk of this ingredient is that it stays functional across a wide pH range (3-10).

You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.

Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.

Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.

Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

Similar Comparisons