Skin science article
SkinCeuticals Sérum A.G.E. Interrupter Ultra Versus SkinCeuticals P-Tiox Wrinkle Modulating Peptide Serum
SkinCeuticals Sérum A.G.E. Interrupter Ultra Versus SkinCeuticals P-Tiox Wrinkle Modulating Peptide Serum This anti-aging serum is formulated around Ectoin and Adenosine to soften the look of wrinkles and strengthen the skin barrier. This anti-aging serum is f
SkinCeuticals Sérum A.G.E. Interrupter Ultra Versus SkinCeuticals P-Tiox Wrinkle Modulating Peptide Serum
This anti-aging serum is formulated around Ectoin and Adenosine to soften the look of wrinkles and strengthen the skin barrier.
This anti-aging serum is formulated around Dipeptide Diaminobutyroyl Benzylamide Diacetate and Acetyl Hexapeptide-8 to soften the look of wrinkles and refine skin texture.
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Propylene Glycol
Hydroxypropyl Tetrahydropyrantriol
Glycerin
Dimethicone
Cetearyl Isononanoate
Isohexadecane
PEG/PPG/Polybutylene Glycol-8/5/3 Glycerin
Diisopropyl Sebacate
Vp/Va Copolymer
Hydroxyacetophenone
Phenoxyethanol
Polysilicone-11
Cellulose
Hydrogenated Lecithin
Xanthan Gum
Propanediol
Acrylates/C10-30 Alkyl Acrylate Crosspolymer
Caprylyl Glycol
Panthenol
Rhamnose
Ectoin
Cassia Alata Leaf Extract
Maltodextrin
Sorbitol
Vaccinium Myrtillus Fruit Extract
Sodium Hydroxide
Adenosine
Trisodium Ethylenediamine Disuccinate
Punica Granatum Fruit Extract
Gentiana Lutea Root Extract
Hydrolyzed Soy Protein
Sodium Benzoate
Potassium Sorbate
Citric Acid
Parfum
Water, Propylene Glycol, Hydroxypropyl Tetrahydropyrantriol, Glycerin, Dimethicone, Cetearyl Isononanoate, Isohexadecane, PEG/PPG/Polybutylene Glycol-8/5/3 Glycerin, Diisopropyl Sebacate, Vp/Va Copolymer, Hydroxyacetophenone, Phenoxyethanol, Polysilicone-11, Cellulose, Hydrogenated Lecithin, Xanthan Gum, Propanediol, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Caprylyl Glycol, Panthenol, Rhamnose, Ectoin, Cassia Alata Leaf Extract, Maltodextrin, Sorbitol, Vaccinium Myrtillus Fruit Extract, Sodium Hydroxide, Adenosine, Trisodium Ethylenediamine Disuccinate, Punica Granatum Fruit Extract, Gentiana Lutea Root Extract, Hydrolyzed Soy Protein, Sodium Benzoate, Potassium Sorbate, Citric Acid, Parfum
Niacinamide
Gluconolactone
Butylene Glycol
Alcohol Denat.
Pentylene Glycol
Methyl Gluceth-20
Potassium Hydroxide
Hydroxyethylcellulose
Salicylic Acid
Chlorphenesin
Phytic Acid
Laminaria Digitata Extract
Dipeptide Diaminobutyroyl Benzylamide Diacetate
Acetyl Hexapeptide-8
Water, Niacinamide, Gluconolactone, Butylene Glycol, PEG/PPG/Polybutylene Glycol-8/5/3 Glycerin, Alcohol Denat., Pentylene Glycol, Methyl Gluceth-20, Glycerin, Potassium Hydroxide, Hydroxyethylcellulose, Salicylic Acid, Chlorphenesin, Phytic Acid, Adenosine, Sodium Benzoate, Laminaria Digitata Extract, Dipeptide Diaminobutyroyl Benzylamide Diacetate, Acetyl Hexapeptide-8
Reviews
Be the first to review
Alternatives
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Adenosine is a purine nucleoside that your body already makes in every cell. In skincare, it acts mainly as a skin conditioning and anti-aging agent.
The way it works is fairly well mapped out:
Your skin has cells called fibroblasts that build collagen (the stuff that keeps skin firm and smooth). Adenosine basically flips a switch on these cells that tells them to get to work making more collagen and other proteins. These cells slow down on their own as skin ages, so Adenosine helps give them a little nudge to keep going.
The clinical backing is pretty solid too.
A blind, randomized, placebo-controlled trial of 126 women aged 45-65 tested a 0.1% cream twice daily and found real improvements in crow's feet and frown lines using a precise 3D skin-mapping technique; these changes showed up by week 3 and held at 2 months.
A later study using Adenosine-loaded dissolving microneedle patches reported gains in wrinkle depth, dermal density, elasticity, and hydration.
On concentrations, South Korea's Ministry of Food and Drug Safety has set 0.04% as the approved functional anti-wrinkle level. You'll typically see this ingredient used somewhere in the 0.04-0.1% range since it works at low doses.
This ingredient has been found safe for cosmetics with the data showing no irritation or sensitization.
Overall, this is a great ingredient for any anti-aging routine and has no photosensitizing effect, so it suits both AM and PM use.
Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
This ingredient is a water-soluble emollient and is derived from glycerin. It also has surfactant properties and can help dissolve oils or actives in water-based products.
According to the manufacturer, this ingredient:
Moisturizes without stickiness or greasiness.
Improves the penetration of water-based ingredients while reducing penetration of oil-based ones to help balance delivery in formulations
Sodium Benzoate is a preservative. It's used in both cosmetic and food products to inhibit the growth of mold and bacteria. It is typically produced synthetically.
Both the US FDA and EU Health Committee have approved the use of sodium benzoate. In the US, levels of 0.1% (of the total product) are allowed.
Sodium benzoate works as a preservative by inhibiting the growth of bacteria inside of cells. It prevents the cell from fermenting a type of sugar using an enzyme called phosphofructokinase.
It is the salt of benzoic acid. Foods containing sodium benzoate include soda, salad dressings, condiments, fruit juices, wines, and snack foods.
Studies for using ascorbic acid and sodium benzoate in cosmetics are lacking, especially in skincare routines with multiple steps.
We always recommend speaking with a professional, such as a dermatologist, if you have any concerns.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!